Ajda Ota - Academia.edu (original) (raw)

Papers by Ajda Ota

Research paper thumbnail of Resveratrol-loaded liposomes: Interaction of resveratrol with phospholipids

European Journal of Lipid Science and Technology, 2015

Research paper thumbnail of Biological potential of nanomaterials strongly depends on the suspension media: experimental data on the effects of fullerene C60 on membranes

Protoplasma, Jan 2, 2015

Fullerenes (C60) are some of the most promising carbon nanomaterials to be used for medical appli... more Fullerenes (C60) are some of the most promising carbon nanomaterials to be used for medical applications as drug delivery agents. Computational and experimental studies have proposed their ability to enter cells by penetrating lipid bilayers. The aim of our study was to provide experimental evidence on whether pristine C60 in physiological media could penetrate cell membranes. The effect was tested on phospholipid vesicles (liposomes) composed of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine, and validated on isolated human red blood cells (RBCs). We incubated the liposomes in an aqueous suspension of C60 and dissolved the lipids and C60 together in chloroform and subsequently formatted the liposomes. By differential scanning calorimetry measurements, we assessed the effect of C60 on the phospholipid thermal profile. The latter was not affected after the incubation of liposomes in the C60 suspension; also, a shape transformation of RBCs did not occur. Differently, by dispersing both C...

Research paper thumbnail of Impact of Coenzyme Q10 on the Physical Properties of Model Lipid Membranes

International Journal of Membrane Science and Technology, 2015

Research paper thumbnail of Archaeosomes can efficiently deliver different types of cargo into epithelial cells grown in vitro

Journal of Biotechnology, 2014

Research paper thumbnail of Morphology, Biophysical Properties and Protein-Mediated Fusion of Archaeosomes

Research paper thumbnail of Effect of flavonoid structure on the fluidity of model lipid membranes

Research paper thumbnail of Flavonoids and cell membrane fluidity

Research paper thumbnail of Interactions of p-coumaric, caffeic and ferulic acids and their styrenes with model lipid membranes

Research paper thumbnail of Stability of diether C25,25 liposomes from the hyperthermophilic archaeon Aeropyrum pernix K1

Chemistry and Physics of Lipids, 2011

Research paper thumbnail of Effect of Growth Medium pH of Aeropyrum pernix on Structural Properties and Fluidity of Archaeosomes

Research paper thumbnail of Kaempferol and quercetin interactions with model lipid membranes

Food Research International, 2015

Research paper thumbnail of Resveratrol-loaded liposomes: Interaction of resveratrol with phospholipids

European Journal of Lipid Science and Technology, 2015

Research paper thumbnail of Biological potential of nanomaterials strongly depends on the suspension media: experimental data on the effects of fullerene C60 on membranes

Protoplasma, Jan 2, 2015

Fullerenes (C60) are some of the most promising carbon nanomaterials to be used for medical appli... more Fullerenes (C60) are some of the most promising carbon nanomaterials to be used for medical applications as drug delivery agents. Computational and experimental studies have proposed their ability to enter cells by penetrating lipid bilayers. The aim of our study was to provide experimental evidence on whether pristine C60 in physiological media could penetrate cell membranes. The effect was tested on phospholipid vesicles (liposomes) composed of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine, and validated on isolated human red blood cells (RBCs). We incubated the liposomes in an aqueous suspension of C60 and dissolved the lipids and C60 together in chloroform and subsequently formatted the liposomes. By differential scanning calorimetry measurements, we assessed the effect of C60 on the phospholipid thermal profile. The latter was not affected after the incubation of liposomes in the C60 suspension; also, a shape transformation of RBCs did not occur. Differently, by dispersing both C...

Research paper thumbnail of Impact of Coenzyme Q10 on the Physical Properties of Model Lipid Membranes

International Journal of Membrane Science and Technology, 2015

Research paper thumbnail of Archaeosomes can efficiently deliver different types of cargo into epithelial cells grown in vitro

Journal of Biotechnology, 2014

Research paper thumbnail of Morphology, Biophysical Properties and Protein-Mediated Fusion of Archaeosomes

Research paper thumbnail of Effect of flavonoid structure on the fluidity of model lipid membranes

Research paper thumbnail of Flavonoids and cell membrane fluidity

Research paper thumbnail of Interactions of p-coumaric, caffeic and ferulic acids and their styrenes with model lipid membranes

Research paper thumbnail of Stability of diether C25,25 liposomes from the hyperthermophilic archaeon Aeropyrum pernix K1

Chemistry and Physics of Lipids, 2011

Research paper thumbnail of Effect of Growth Medium pH of Aeropyrum pernix on Structural Properties and Fluidity of Archaeosomes

Research paper thumbnail of Kaempferol and quercetin interactions with model lipid membranes

Food Research International, 2015