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Papers by Alan Craft

Research paper thumbnail of Seasonal Variation in Birth and Diagnosis of Cancer in Children and Young People in Northern England, 1968-2005

Epidemiology, Nov 1, 2009

Research paper thumbnail of Are health services in England failing our children?

Research paper thumbnail of Intestinal permeability tests and integrity of the small intestinal mucosa

Archives of Disease in Childhood, Feb 1, 1989

Research paper thumbnail of Covert video surveillance: an important investigative tool or a breach of trust?

Archives of Disease in Childhood, Oct 1, 1999

Research paper thumbnail of Updated investigations of cancer excesses in individuals born or resident in the vicinity of Sellafield and Dounreay

British Journal of Cancer, Jul 22, 2014

Research paper thumbnail of Circumstances surrounding deaths from accidental poisoning 1974-80

Archives of Disease in Childhood, Jul 1, 1983

Research paper thumbnail of CT scans in young people in Northern England: trends and patterns 1993–2002

Pediatric Radiology, May 19, 2011

Research paper thumbnail of The 'grey toddler'. Chloramphenicol toxicity

Archives of Disease in Childhood, Mar 1, 1974

Research paper thumbnail of Height at diagnosis and birth-weight as risk factors for osteosarcoma

Cancer Causes & Control, Apr 5, 2011

Research paper thumbnail of Intestinal permeability in children with Crohn's disease and coeliac disease

Research paper thumbnail of Implications of childhood obesity for adult health: findings from thousand families cohort study

Research paper thumbnail of MSbP and sudden infant death: authors' reply

Research paper thumbnail of Jonathan Pritchard

Research paper thumbnail of P1-97 Demographic analysis of osteosarcoma and ewing sarcoma family of tumours in 0-49 year olds in Great Britain, 1980-2005: a small-area approach

Journal of Epidemiology and Community Health, Aug 1, 2011

Research paper thumbnail of John Duncan Hay

Research paper thumbnail of 038 Survival from childhood and young adult cancer in the north of England, 1968-2005

Journal of Epidemiology and Community Health, Sep 1, 2010

Research paper thumbnail of Low dose continuous infusion doxorubicin in children and young adults

Medical and Pediatric Oncology, 1993

Ten patients (age range 3.2-26.3 yrs) with relapsed or resistant malignancies received a total of... more Ten patients (age range 3.2-26.3 yrs) with relapsed or resistant malignancies received a total of 20 courses of low dose continuous infusion doxorubicin (3 mg/m2/day for 28 days) delivered by portable Graseby infusion pumps via central venous catheters. Each patient received a median dose of 144 mg/m2 (range 87-261). Four patients responded to treatment (1 complete response (CR) and 3 partial response (PR)) and performance status improved in seven patients. Overall toxicity was minimal: WHO Grade 4 anaemia in 2/18 courses, Grade 4 neutropenia in 1/18, Grade 3-4 thrombocytopenia in 3/18, nausea and vomiting of Grades 2 and 4 in 4/20 and 1/20 respectively, and mucositis of Grades 2 and 4 in 2/20 courses each. Cardiac toxicity was assessed using echocardiography, and fractional shortening remained within normal limits in all patients. Low dose continuous infusion doxorubicin is a feasible, well tolerated, ambulatory therapy in children and may be an effective way of delivering doxorubicin with less toxicity, thus enabling the development of more dose intensive regimens.

Research paper thumbnail of Response to: Comment on 'Updated investigations of cancer excesses in individuals born or resident in the vicinity of Sellafield and Dounreay

British Journal of Cancer, Nov 20, 2014

Research paper thumbnail of Letter: Poisoned children

Research paper thumbnail of Letter to the editor: Ominous trend in childhood cancer mortality?

Medical and Pediatric Oncology, 2001

Research paper thumbnail of Seasonal Variation in Birth and Diagnosis of Cancer in Children and Young People in Northern England, 1968-2005

Epidemiology, Nov 1, 2009

Research paper thumbnail of Are health services in England failing our children?

Research paper thumbnail of Intestinal permeability tests and integrity of the small intestinal mucosa

Archives of Disease in Childhood, Feb 1, 1989

Research paper thumbnail of Covert video surveillance: an important investigative tool or a breach of trust?

Archives of Disease in Childhood, Oct 1, 1999

Research paper thumbnail of Updated investigations of cancer excesses in individuals born or resident in the vicinity of Sellafield and Dounreay

British Journal of Cancer, Jul 22, 2014

Research paper thumbnail of Circumstances surrounding deaths from accidental poisoning 1974-80

Archives of Disease in Childhood, Jul 1, 1983

Research paper thumbnail of CT scans in young people in Northern England: trends and patterns 1993–2002

Pediatric Radiology, May 19, 2011

Research paper thumbnail of The 'grey toddler'. Chloramphenicol toxicity

Archives of Disease in Childhood, Mar 1, 1974

Research paper thumbnail of Height at diagnosis and birth-weight as risk factors for osteosarcoma

Cancer Causes & Control, Apr 5, 2011

Research paper thumbnail of Intestinal permeability in children with Crohn's disease and coeliac disease

Research paper thumbnail of Implications of childhood obesity for adult health: findings from thousand families cohort study

Research paper thumbnail of MSbP and sudden infant death: authors' reply

Research paper thumbnail of Jonathan Pritchard

Research paper thumbnail of P1-97 Demographic analysis of osteosarcoma and ewing sarcoma family of tumours in 0-49 year olds in Great Britain, 1980-2005: a small-area approach

Journal of Epidemiology and Community Health, Aug 1, 2011

Research paper thumbnail of John Duncan Hay

Research paper thumbnail of 038 Survival from childhood and young adult cancer in the north of England, 1968-2005

Journal of Epidemiology and Community Health, Sep 1, 2010

Research paper thumbnail of Low dose continuous infusion doxorubicin in children and young adults

Medical and Pediatric Oncology, 1993

Ten patients (age range 3.2-26.3 yrs) with relapsed or resistant malignancies received a total of... more Ten patients (age range 3.2-26.3 yrs) with relapsed or resistant malignancies received a total of 20 courses of low dose continuous infusion doxorubicin (3 mg/m2/day for 28 days) delivered by portable Graseby infusion pumps via central venous catheters. Each patient received a median dose of 144 mg/m2 (range 87-261). Four patients responded to treatment (1 complete response (CR) and 3 partial response (PR)) and performance status improved in seven patients. Overall toxicity was minimal: WHO Grade 4 anaemia in 2/18 courses, Grade 4 neutropenia in 1/18, Grade 3-4 thrombocytopenia in 3/18, nausea and vomiting of Grades 2 and 4 in 4/20 and 1/20 respectively, and mucositis of Grades 2 and 4 in 2/20 courses each. Cardiac toxicity was assessed using echocardiography, and fractional shortening remained within normal limits in all patients. Low dose continuous infusion doxorubicin is a feasible, well tolerated, ambulatory therapy in children and may be an effective way of delivering doxorubicin with less toxicity, thus enabling the development of more dose intensive regimens.

Research paper thumbnail of Response to: Comment on 'Updated investigations of cancer excesses in individuals born or resident in the vicinity of Sellafield and Dounreay

British Journal of Cancer, Nov 20, 2014

Research paper thumbnail of Letter: Poisoned children

Research paper thumbnail of Letter to the editor: Ominous trend in childhood cancer mortality?

Medical and Pediatric Oncology, 2001

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