Aldo Morra - Academia.edu (original) (raw)

Papers by Aldo Morra

Research paper thumbnail of Coronary MR angiography in the diagnosis of anomalous origin of the coronary arteries: Safe for children

Coronary MR angiography in the diagnosis of anomalous origin of the coronary arteries: Safe for children

Research paper thumbnail of S Kadir, Editor, Teaching atlas of interventional radiology: non-vascular interventional procedures, Thieme, New York, Stuttgart (2006) ISBN 1-58890-056-8 336 pages, 314 illustrations, US$ 119.95

S Kadir, Editor, Teaching atlas of interventional radiology: non-vascular interventional procedures, Thieme, New York, Stuttgart (2006) ISBN 1-58890-056-8 336 pages, 314 illustrations, US$ 119.95

Clin Imag, 2006

Research paper thumbnail of Book reviewB Funaki, J Lorenz, T Van Ha, Teaching Atlas of Vascular and Non-Vascular Interventional Radiology, Thieme, New York/Stuttgart, Philadelphia, PA (2007), 388 pages, 450 illustrations, US$129.95, ISBN: 978-1-58890-625-0

Book reviewB Funaki, J Lorenz, T Van Ha, Teaching Atlas of Vascular and Non-Vascular Interventional Radiology, Thieme, New York/Stuttgart, Philadelphia, PA (2007), 388 pages, 450 illustrations, US$129.95, ISBN: 978-1-58890-625-0

Clinical Imaging, Jul 1, 2008

Research paper thumbnail of Abstract 2005: Coronary Calcium Score by Multislice Computer Tomography Does Not Predict Atherosclerotic Plaques at Risk of Sudden Death in the Young

Abstract 2005: Coronary Calcium Score by Multislice Computer Tomography Does Not Predict Atherosclerotic Plaques at Risk of Sudden Death in the Young

Circulation, Oct 28, 2008

Research paper thumbnail of ECR2008_C-246: CT angiography and 3D post processing in the evaluation of congenital vascular anomalies of the thorax

ECR2008_C-246: CT angiography and 3D post processing in the evaluation of congenital vascular anomalies of the thorax

Research paper thumbnail of High Resolution CT Angiography in Detection of an Aneurysm of the Vein of Galen as a Source of Intracranial Haemorrhage in a Newborn

High Resolution CT Angiography in Detection of an Aneurysm of the Vein of Galen as a Source of Intracranial Haemorrhage in a Newborn

The Neuroradiology Journal, 2011

Cerebral haemorrhage is a rare condition in infants and carries a known poor prognosis. Common ca... more Cerebral haemorrhage is a rare condition in infants and carries a known poor prognosis. Common causes of spontaneous haemorrhage include various vascular venous lesions due to incomplete hydrovenous maturation, among them Galen vein aneurysm may be a very rare cause of cerebral haemorrhage. This report emphasizes the role of multidector CT with high resolution CT angiography in a newborn with cerebral hemorrhage caused by Galen vein aneurysm rupture. MDCT with high resolution CT angiography helps to differentiate the cause of haemorrhage, and to address the appropriate treatment.

Research paper thumbnail of A New Sampling Method for Spleen Stiffness Measurement Based on Quantitative Acoustic Radiation Force Impulse Elastography for Noninvasive Assessment of Esophageal Varices in Newly Diagnosed HCV-Related Cirrhosis

BioMed Research International, 2014

In our study, we evaluated the feasibility of a new sampling method for splenic stiffness (SS) me... more In our study, we evaluated the feasibility of a new sampling method for splenic stiffness (SS) measurement by Quantitative Acoustic Radiation Force Impulse Elastography (Virtual Touch Tissue Quantification (VTTQ)).We measured SS in 54 patients with HCV-related cirrhosis of whom 28 with esophageal varices (EV), 27 with Chronic Hepatitis C (CHC) F1–F3, and 63 healthy controls. VTTQ-SS was significantly higher among cirrhotic patients with EV (3.37 m/s) in comparison with controls (2.19 m/s,P<0.001), CHC patients (2.37 m/s,P<0.001), and cirrhotic patients without EV (2.7 m/s,P<0.001). Moreover, VTTQ-SS was significantly higher among cirrhotic patients without EV in comparison with both controls (P<0.001) and CHC patients (P<0.01). The optimal VTTQ-SS cut-off value for predicting EV was 3.1 m/s (AUROC = 0.96, sensitivity 96.4%, specificity 88.5%, positive predictive value 90%, negative predictive value 96%, positive likelihood ratio 8.36, and negative likelihood ratio 0.0...

Research paper thumbnail of Protein Supplementation Increases Postexercise Plasma Myostatin Concentration After 8 Weeks of Resistance Training in Young Physically Active Subjects

Journal of Medicinal Food, 2015

Myostatin (MSTN) is a negative regulator of muscle growth even if some studies have shown a count... more Myostatin (MSTN) is a negative regulator of muscle growth even if some studies have shown a counterintuitive positive correlation between MSTN and muscle mass (MM). Our aim was to investigate the influence of 2 months of resistance training (RT) and diets with different protein contents on plasma MSTN, interleukin 1 beta (IL-1b), interleukin 6 (IL-6), tumor necrosis factor alpha (TNF-a), and insulin-like growth factor 1 (IGF-1). Eighteen healthy volunteers were randomly divided in two groups: high protein (HP) and normal protein (NP) groups. Different protein diet contents were 1.8 and 0.85 g of protein$kg bw -1 $day -1 for HP and NP, respectively. Subjects underwent 8 weeks of standardized progressive RT. MSTN, IGF-1, IL-1b, IL-6, and TNF-a were analyzed before and after the first and the last training sessions. Lean body mass, MM, upper-limb muscle area, and strength were measured. Plasma MSTN showed a significant increase (P < .001) after the last training in the HP group compared with NP group and with starting value. IGF-1 plasma concentration showed a positive correlation with MSTN in HP after the last training (r 2 = 0.6456; P = .0295). No significant differences were found between NP and HP for IL-1b, IL-6, TNF-a, and strength and MM or area. These findings suggest a ''paradoxical'' postexercise increase of plasma MSTN after 8 weeks of RT and HP diets. This MSTN elevation correlates positively with IGF-1 plasma level. This double increase of opposite (catabolic/anabolic) mediators could explain the substantial overlapping of MM increases in the two groups.

Research paper thumbnail of Gary P. Siskin, Editor, Interventional radiology in women's health, Thieme, New York/Stuttgart (2009) ISBN 978-1-60406-046-1, p. 288 38 tables, 90 illustrations, US$119.95

Gary P. Siskin, Editor, Interventional radiology in women's health, Thieme, New York/Stuttgart (2009) ISBN 978-1-60406-046-1, p. 288 38 tables, 90 illustrations, US$119.95

Clinical Imaging, 2010

Research paper thumbnail of Metastatic Angiosarcoma of the Kidney: A Case Report with Treatment Approach and Review of the Literature

Journal of Chemotherapy, 2006

Angiosarcomas are rare soft tissue malignancies. Typically they originate from the skin of the sc... more Angiosarcomas are rare soft tissue malignancies. Typically they originate from the skin of the scalp or face, whereas visceral sarcomas are very rare. We report the case of a 67-year-old man affected by a large angiosarcoma of the kidney. After surgical removal, a rapid peritoneal, visceral and cutaneous diffusion developed. Palliative chemotherapy, based on anthracycline and ifosfamide, which are normally used to treat all other high-grade spindle cell sarcomas, was totally inactive. On the basis of these results and of the biological characteristics of these rare neoplasms it is mandatory to develop other therapeutic approaches. Antiangiogenetic agents are of interest for this disease due to the peculiar origin of the cells of these sarcomas.

Research paper thumbnail of Noninvasive evaluation of a fistula between a giant coronary aneurysm and coronary sinus performed via multidetector row computed tomography

Clinical Imaging, 2006

Coronary artery fistula (CAF) is an uncommon anomaly of congenital and rarely iatrogenic etiology... more Coronary artery fistula (CAF) is an uncommon anomaly of congenital and rarely iatrogenic etiology. Most of the patients are asymptomatic, and the anomaly is incidentally recognized during a coronary angiography performed for other reasons. Also, coronary artery aneurysms are rare. We report a case of CAF associated with a giant aneurysm evaluated using multidetector row computed tomography.

Research paper thumbnail of An anatomo-radiological study on the pattern of branching of the left portal vein

An anatomo-radiological study on the pattern of branching of the left portal vein

Italian journal of anatomy and embryology, 2010

Branching anomalies of the left portal vein can be managed safely with new surgical techniques bu... more Branching anomalies of the left portal vein can be managed safely with new surgical techniques but they can represent contraindications for living donor transplantation. Moreover, in children with extrahepatic portal vein obstruction a successful shunting requires detailed ...

Research paper thumbnail of The paratendineous tissues: an anatomical study of their role in the pathogenesis of tendinopathy

The paratendineous tissues: an anatomical study of their role in the pathogenesis of tendinopathy

Surgical and Radiologic Anatomy, 2013

The aim of this paper was to examine the macroscopic and microscopic characteristics of the parat... more The aim of this paper was to examine the macroscopic and microscopic characteristics of the paratendineous tissues (paratenon, epitenon and endotenon) of the calcaneal tendon to better understand their role in the pathogenesis of &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;quot;tendinopathy&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;quot;. Ten non-embalmed legs from cadavers were used. Histological and immunohistochemical studies were done at the middle third of the tendon. Magnetic resonance images of the hind foot were made in 60 living subjects to analyze the morphological alterations of tendon and paratenon. The paratenon is a thick fibrous layer with few elastic fibers, continuous with the crural fascia, well vascularized and innervated. It forms a sheath around the tendon similar to a synovial layer, but less organized. Indeed, it has no complete epithelium, but only some cells producing hyaluronan, called fasciacytes. Crural fascia and paratenon can be clearly observed by MRI, appearing as homogeneous, low signal intensity bands, sharply defined in the context of subcutaneous tissue in T1-weighted sequences. The mean thickness of the crural fascia was 1.11 mm in healthy subjects and 1.30 mm in patients (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.005). The mean value of paratenon thickness in patients was 1.34 mm, 0.85 in healthy (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.0001). The paratenon is more highly vascularized and innervated than the tendon, supporting the hypothesis that it is the origin of pain in tendinopathy. The imaging study suggests that, an increase in the thickness of the paratenon more than 1.35 mm is predictive of paratendinopathy, even before tendon damage.

Research paper thumbnail of Reversed Gracilis Pedicle Flap for Coverage of a Total Knee Prosthesis*

Journal of Bone and Joint Surgery, 2010

Background.dPoor wound-healing and skin necrosis are potentially devastating complications after ... more Background.dPoor wound-healing and skin necrosis are potentially devastating complications after total knee arthroplasty. Primary soft-tissue coverage with a medial or lateral gastrocnemius transposition flap is Chapter 8eGrafts, Flaps, and Microsurgery / 239

Research paper thumbnail of Anatomico-radiologic study of the distribution of the suboccipital artery of Salmon

Clinical Neurology and Neurosurgery, 2014

Objectives: The frequency of suboccipital injections to treat headaches has increased. The third ... more Objectives: The frequency of suboccipital injections to treat headaches has increased. The third segment of the vertebral artery is located in the suboccipital triangle and its main muscular branch, the suboccipital artery of Salmon (SAS), supplies blood to the suboccipital muscles. The purpose of this study was to radiographically investigate the morphology and territory of distribution of SAS. Patients and methods: Computed tomography angiographs of brains of 50 subjects (25 female, 25 men, mean age 70.2 years) were analyzed. Results: SAS was present in 48% of subjects. The vessel was present bilaterally in 37.1%, and had a mean (SD) luminal diameter of 1.71 (0.34) mm and mean (SD) length of 36.42 (17.1) mm. SAS was found to have two morphologic patterns: (1) a single main trunk with collateral branches (52.6%) and (2) a short common trunk that divided into two branches (48.4%). The SAS supplied the obliquus capitis inferior, semispinalis capitis, and splenius capitis muscles. When the SAS was absent, the suboccipital muscles were supplied by a branch of the occipital artery. No anastomoses were found between the SAS and occipital artery. The suboccipital muscles are vascularized by the SAS and occipital artery. The detailed course of the SAS is important for clinicians and surgeons who perform procedures in the suboccipital region.

Research paper thumbnail of The Ankle Retinacula: Morphological Evidence of the Proprioceptive Role of the Fascial System

Cells Tissues Organs, 2010

Study Design: Research report. Objectives: To evaluate the anatomical characteristics of the ankl... more Study Design: Research report. Objectives: To evaluate the anatomical characteristics of the ankle retinacula and their relationship with the fasciae and muscles in healthy subjects and in patients with ankle sprain outcomes. Background: The role of the retinacula in proprioception has begun to emerge, but without clear anatomical bases or descriptions of their possible damage in patients with ankle sprain outcomes. Methods: Dissection, histological and immunohistochemical analysis of 27 legs. An in vivo radiological study by MRI was also performed on 7 healthy volunteers, 17 patients with outcomes of ankle sprain, and 3 amputated legs. Results: The retinacula are thickenings of the deep fascia presenting bone or muscular connections. They are formed of 2–3 layers of parallel collagen fibre bundles, densely packaged with a little loose connective tissue, without elastic fibres but many nervous fibres and corpuscles. By MRI, the retinacula appeared as low-signal-intensity bands with ...

Research paper thumbnail of The clinical role of the gracilis muscle: an example of multidisciplinary collaboration

The clinical role of the gracilis muscle: an example of multidisciplinary collaboration

pelviperineology.com

... ENRICO VIGATO(*) - VERONICA MACCHI(**) - CESARE TIENGO(*) - BRUNO AZZENA(*) ANDREA PORZIONATO... more ... ENRICO VIGATO(*) - VERONICA MACCHI(**) - CESARE TIENGO(*) - BRUNO AZZENA(*) ANDREA PORZIONATO(*) - ALDO MORRA(**** CARLA STECCO(*) - GIUSEPPE DODI ... 12. Juricic M, Vaysse P, Guitard J, Moscovici J. Anatomic bases for use of a gracilis muscle flap. ...

Research paper thumbnail of Vascular and Interventional Imaging: Case Review Series, 2nd ed

American Journal of Roentgenology, 2011

Research paper thumbnail of Anatomical study of renal arterial vasculature and its potential impact on partial nephrectomy

BJUI, Feb 20, 2017

To validate Graves' classification of the intrarenal arteries and to verify the absence of collat... more To validate Graves' classification of the intrarenal arteries and to verify the absence of collateral arterial blood supply between different renal segments, in order to maximize peri-operative and functional outcomes of partial nephrectomy. Materials and Methods The study was performed on 15 normal kidneys sampled from eight unembalmed cadavers. Kidneys with the surrounding perirenal fat tissue were removed en bloc with the abdominal segment of the aorta. The renal artery was injected with acrylic and radiopaque resins, with the specimen suspended in water. CT examination of the injected kidneys was performed to analyse the branches located deeply. After imaging acquisition, the specimens were treated with sodium hydroxide for removal of the parenchyma to obtain vascular casts. Results Ten casts (66.6%) showed the classic subdivision of the main artery into single posterior and anterior branches. With regard to the distribution of the segmental or second-order arteries, only two casts (13%) showed a pattern similar to that described by Graves, characterized by four segmental (secondorder) branches coming from the anterior renal artery (apical, superior, middle and inferior). In the remaining 13 kidneys (87%) a different arterial vascular network was detected. In 10 casts (80%) a single renal segment was vascularized by two or more different branches coming from an artery leading to another segment (multiple vascularization). Multiple vascularization was observed in three (20%) apical segments, five (33%) superior segments, six (40%) middle segments, seven (47%) inferior segments and two (13%) posterior segments. Conclusions This study shows that in the human kidneys the arterial vasculature is frequently different from that described by Graves. Moreover, in a significant percentage of cases, a single renal segment receives two or more branches that originate from an artery leading to another segment.

Research paper thumbnail of Double origin of the superior cerebellar artery associated with homolateral haemorrhagic infarction of cerebellum

Folia Neuropathologica, 2016

The superior cerebellar artery (SCA) shows the least variable course and the lowest incidence of ... more The superior cerebellar artery (SCA) shows the least variable course and the lowest incidence of anatomical variations among cerebellar arteries. In the present study, an 84-year-old woman was affected by a cerebellar infarction which underwent haemorrhagic evolution in the following days. Neuroimaging investigations also showed a probable double origin of the left SCA. Neuropathological examination confirmed the presence of a large haemorrhagic infarction at the level of the superior portion of the left cerebellar hemisphere and vermis. The left SCA arose from two small arteries arising from the left aspect of the basilar artery and joining together after a course of 9 mm. Previous studies have reported the association of cerebrovascular pathologies, such as intracranial aneurysms, with fenestrations and double origins of the posterior inferior cerebellar artery. In the present case, the occurrence of an haemorrhagic infarction in the vascular field of an SCA with double origin is intriguing in suggesting a possible pathophysiological association.

Research paper thumbnail of Coronary MR angiography in the diagnosis of anomalous origin of the coronary arteries: Safe for children

Coronary MR angiography in the diagnosis of anomalous origin of the coronary arteries: Safe for children

Research paper thumbnail of S Kadir, Editor, Teaching atlas of interventional radiology: non-vascular interventional procedures, Thieme, New York, Stuttgart (2006) ISBN 1-58890-056-8 336 pages, 314 illustrations, US$ 119.95

S Kadir, Editor, Teaching atlas of interventional radiology: non-vascular interventional procedures, Thieme, New York, Stuttgart (2006) ISBN 1-58890-056-8 336 pages, 314 illustrations, US$ 119.95

Clin Imag, 2006

Research paper thumbnail of Book reviewB Funaki, J Lorenz, T Van Ha, Teaching Atlas of Vascular and Non-Vascular Interventional Radiology, Thieme, New York/Stuttgart, Philadelphia, PA (2007), 388 pages, 450 illustrations, US$129.95, ISBN: 978-1-58890-625-0

Book reviewB Funaki, J Lorenz, T Van Ha, Teaching Atlas of Vascular and Non-Vascular Interventional Radiology, Thieme, New York/Stuttgart, Philadelphia, PA (2007), 388 pages, 450 illustrations, US$129.95, ISBN: 978-1-58890-625-0

Clinical Imaging, Jul 1, 2008

Research paper thumbnail of Abstract 2005: Coronary Calcium Score by Multislice Computer Tomography Does Not Predict Atherosclerotic Plaques at Risk of Sudden Death in the Young

Abstract 2005: Coronary Calcium Score by Multislice Computer Tomography Does Not Predict Atherosclerotic Plaques at Risk of Sudden Death in the Young

Circulation, Oct 28, 2008

Research paper thumbnail of ECR2008_C-246: CT angiography and 3D post processing in the evaluation of congenital vascular anomalies of the thorax

ECR2008_C-246: CT angiography and 3D post processing in the evaluation of congenital vascular anomalies of the thorax

Research paper thumbnail of High Resolution CT Angiography in Detection of an Aneurysm of the Vein of Galen as a Source of Intracranial Haemorrhage in a Newborn

High Resolution CT Angiography in Detection of an Aneurysm of the Vein of Galen as a Source of Intracranial Haemorrhage in a Newborn

The Neuroradiology Journal, 2011

Cerebral haemorrhage is a rare condition in infants and carries a known poor prognosis. Common ca... more Cerebral haemorrhage is a rare condition in infants and carries a known poor prognosis. Common causes of spontaneous haemorrhage include various vascular venous lesions due to incomplete hydrovenous maturation, among them Galen vein aneurysm may be a very rare cause of cerebral haemorrhage. This report emphasizes the role of multidector CT with high resolution CT angiography in a newborn with cerebral hemorrhage caused by Galen vein aneurysm rupture. MDCT with high resolution CT angiography helps to differentiate the cause of haemorrhage, and to address the appropriate treatment.

Research paper thumbnail of A New Sampling Method for Spleen Stiffness Measurement Based on Quantitative Acoustic Radiation Force Impulse Elastography for Noninvasive Assessment of Esophageal Varices in Newly Diagnosed HCV-Related Cirrhosis

BioMed Research International, 2014

In our study, we evaluated the feasibility of a new sampling method for splenic stiffness (SS) me... more In our study, we evaluated the feasibility of a new sampling method for splenic stiffness (SS) measurement by Quantitative Acoustic Radiation Force Impulse Elastography (Virtual Touch Tissue Quantification (VTTQ)).We measured SS in 54 patients with HCV-related cirrhosis of whom 28 with esophageal varices (EV), 27 with Chronic Hepatitis C (CHC) F1–F3, and 63 healthy controls. VTTQ-SS was significantly higher among cirrhotic patients with EV (3.37 m/s) in comparison with controls (2.19 m/s,P<0.001), CHC patients (2.37 m/s,P<0.001), and cirrhotic patients without EV (2.7 m/s,P<0.001). Moreover, VTTQ-SS was significantly higher among cirrhotic patients without EV in comparison with both controls (P<0.001) and CHC patients (P<0.01). The optimal VTTQ-SS cut-off value for predicting EV was 3.1 m/s (AUROC = 0.96, sensitivity 96.4%, specificity 88.5%, positive predictive value 90%, negative predictive value 96%, positive likelihood ratio 8.36, and negative likelihood ratio 0.0...

Research paper thumbnail of Protein Supplementation Increases Postexercise Plasma Myostatin Concentration After 8 Weeks of Resistance Training in Young Physically Active Subjects

Journal of Medicinal Food, 2015

Myostatin (MSTN) is a negative regulator of muscle growth even if some studies have shown a count... more Myostatin (MSTN) is a negative regulator of muscle growth even if some studies have shown a counterintuitive positive correlation between MSTN and muscle mass (MM). Our aim was to investigate the influence of 2 months of resistance training (RT) and diets with different protein contents on plasma MSTN, interleukin 1 beta (IL-1b), interleukin 6 (IL-6), tumor necrosis factor alpha (TNF-a), and insulin-like growth factor 1 (IGF-1). Eighteen healthy volunteers were randomly divided in two groups: high protein (HP) and normal protein (NP) groups. Different protein diet contents were 1.8 and 0.85 g of protein$kg bw -1 $day -1 for HP and NP, respectively. Subjects underwent 8 weeks of standardized progressive RT. MSTN, IGF-1, IL-1b, IL-6, and TNF-a were analyzed before and after the first and the last training sessions. Lean body mass, MM, upper-limb muscle area, and strength were measured. Plasma MSTN showed a significant increase (P < .001) after the last training in the HP group compared with NP group and with starting value. IGF-1 plasma concentration showed a positive correlation with MSTN in HP after the last training (r 2 = 0.6456; P = .0295). No significant differences were found between NP and HP for IL-1b, IL-6, TNF-a, and strength and MM or area. These findings suggest a ''paradoxical'' postexercise increase of plasma MSTN after 8 weeks of RT and HP diets. This MSTN elevation correlates positively with IGF-1 plasma level. This double increase of opposite (catabolic/anabolic) mediators could explain the substantial overlapping of MM increases in the two groups.

Research paper thumbnail of Gary P. Siskin, Editor, Interventional radiology in women's health, Thieme, New York/Stuttgart (2009) ISBN 978-1-60406-046-1, p. 288 38 tables, 90 illustrations, US$119.95

Gary P. Siskin, Editor, Interventional radiology in women's health, Thieme, New York/Stuttgart (2009) ISBN 978-1-60406-046-1, p. 288 38 tables, 90 illustrations, US$119.95

Clinical Imaging, 2010

Research paper thumbnail of Metastatic Angiosarcoma of the Kidney: A Case Report with Treatment Approach and Review of the Literature

Journal of Chemotherapy, 2006

Angiosarcomas are rare soft tissue malignancies. Typically they originate from the skin of the sc... more Angiosarcomas are rare soft tissue malignancies. Typically they originate from the skin of the scalp or face, whereas visceral sarcomas are very rare. We report the case of a 67-year-old man affected by a large angiosarcoma of the kidney. After surgical removal, a rapid peritoneal, visceral and cutaneous diffusion developed. Palliative chemotherapy, based on anthracycline and ifosfamide, which are normally used to treat all other high-grade spindle cell sarcomas, was totally inactive. On the basis of these results and of the biological characteristics of these rare neoplasms it is mandatory to develop other therapeutic approaches. Antiangiogenetic agents are of interest for this disease due to the peculiar origin of the cells of these sarcomas.

Research paper thumbnail of Noninvasive evaluation of a fistula between a giant coronary aneurysm and coronary sinus performed via multidetector row computed tomography

Clinical Imaging, 2006

Coronary artery fistula (CAF) is an uncommon anomaly of congenital and rarely iatrogenic etiology... more Coronary artery fistula (CAF) is an uncommon anomaly of congenital and rarely iatrogenic etiology. Most of the patients are asymptomatic, and the anomaly is incidentally recognized during a coronary angiography performed for other reasons. Also, coronary artery aneurysms are rare. We report a case of CAF associated with a giant aneurysm evaluated using multidetector row computed tomography.

Research paper thumbnail of An anatomo-radiological study on the pattern of branching of the left portal vein

An anatomo-radiological study on the pattern of branching of the left portal vein

Italian journal of anatomy and embryology, 2010

Branching anomalies of the left portal vein can be managed safely with new surgical techniques bu... more Branching anomalies of the left portal vein can be managed safely with new surgical techniques but they can represent contraindications for living donor transplantation. Moreover, in children with extrahepatic portal vein obstruction a successful shunting requires detailed ...

Research paper thumbnail of The paratendineous tissues: an anatomical study of their role in the pathogenesis of tendinopathy

The paratendineous tissues: an anatomical study of their role in the pathogenesis of tendinopathy

Surgical and Radiologic Anatomy, 2013

The aim of this paper was to examine the macroscopic and microscopic characteristics of the parat... more The aim of this paper was to examine the macroscopic and microscopic characteristics of the paratendineous tissues (paratenon, epitenon and endotenon) of the calcaneal tendon to better understand their role in the pathogenesis of &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;quot;tendinopathy&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;quot;. Ten non-embalmed legs from cadavers were used. Histological and immunohistochemical studies were done at the middle third of the tendon. Magnetic resonance images of the hind foot were made in 60 living subjects to analyze the morphological alterations of tendon and paratenon. The paratenon is a thick fibrous layer with few elastic fibers, continuous with the crural fascia, well vascularized and innervated. It forms a sheath around the tendon similar to a synovial layer, but less organized. Indeed, it has no complete epithelium, but only some cells producing hyaluronan, called fasciacytes. Crural fascia and paratenon can be clearly observed by MRI, appearing as homogeneous, low signal intensity bands, sharply defined in the context of subcutaneous tissue in T1-weighted sequences. The mean thickness of the crural fascia was 1.11 mm in healthy subjects and 1.30 mm in patients (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.005). The mean value of paratenon thickness in patients was 1.34 mm, 0.85 in healthy (p &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.0001). The paratenon is more highly vascularized and innervated than the tendon, supporting the hypothesis that it is the origin of pain in tendinopathy. The imaging study suggests that, an increase in the thickness of the paratenon more than 1.35 mm is predictive of paratendinopathy, even before tendon damage.

Research paper thumbnail of Reversed Gracilis Pedicle Flap for Coverage of a Total Knee Prosthesis*

Journal of Bone and Joint Surgery, 2010

Background.dPoor wound-healing and skin necrosis are potentially devastating complications after ... more Background.dPoor wound-healing and skin necrosis are potentially devastating complications after total knee arthroplasty. Primary soft-tissue coverage with a medial or lateral gastrocnemius transposition flap is Chapter 8eGrafts, Flaps, and Microsurgery / 239

Research paper thumbnail of Anatomico-radiologic study of the distribution of the suboccipital artery of Salmon

Clinical Neurology and Neurosurgery, 2014

Objectives: The frequency of suboccipital injections to treat headaches has increased. The third ... more Objectives: The frequency of suboccipital injections to treat headaches has increased. The third segment of the vertebral artery is located in the suboccipital triangle and its main muscular branch, the suboccipital artery of Salmon (SAS), supplies blood to the suboccipital muscles. The purpose of this study was to radiographically investigate the morphology and territory of distribution of SAS. Patients and methods: Computed tomography angiographs of brains of 50 subjects (25 female, 25 men, mean age 70.2 years) were analyzed. Results: SAS was present in 48% of subjects. The vessel was present bilaterally in 37.1%, and had a mean (SD) luminal diameter of 1.71 (0.34) mm and mean (SD) length of 36.42 (17.1) mm. SAS was found to have two morphologic patterns: (1) a single main trunk with collateral branches (52.6%) and (2) a short common trunk that divided into two branches (48.4%). The SAS supplied the obliquus capitis inferior, semispinalis capitis, and splenius capitis muscles. When the SAS was absent, the suboccipital muscles were supplied by a branch of the occipital artery. No anastomoses were found between the SAS and occipital artery. The suboccipital muscles are vascularized by the SAS and occipital artery. The detailed course of the SAS is important for clinicians and surgeons who perform procedures in the suboccipital region.

Research paper thumbnail of The Ankle Retinacula: Morphological Evidence of the Proprioceptive Role of the Fascial System

Cells Tissues Organs, 2010

Study Design: Research report. Objectives: To evaluate the anatomical characteristics of the ankl... more Study Design: Research report. Objectives: To evaluate the anatomical characteristics of the ankle retinacula and their relationship with the fasciae and muscles in healthy subjects and in patients with ankle sprain outcomes. Background: The role of the retinacula in proprioception has begun to emerge, but without clear anatomical bases or descriptions of their possible damage in patients with ankle sprain outcomes. Methods: Dissection, histological and immunohistochemical analysis of 27 legs. An in vivo radiological study by MRI was also performed on 7 healthy volunteers, 17 patients with outcomes of ankle sprain, and 3 amputated legs. Results: The retinacula are thickenings of the deep fascia presenting bone or muscular connections. They are formed of 2–3 layers of parallel collagen fibre bundles, densely packaged with a little loose connective tissue, without elastic fibres but many nervous fibres and corpuscles. By MRI, the retinacula appeared as low-signal-intensity bands with ...

Research paper thumbnail of The clinical role of the gracilis muscle: an example of multidisciplinary collaboration

The clinical role of the gracilis muscle: an example of multidisciplinary collaboration

pelviperineology.com

... ENRICO VIGATO(*) - VERONICA MACCHI(**) - CESARE TIENGO(*) - BRUNO AZZENA(*) ANDREA PORZIONATO... more ... ENRICO VIGATO(*) - VERONICA MACCHI(**) - CESARE TIENGO(*) - BRUNO AZZENA(*) ANDREA PORZIONATO(*) - ALDO MORRA(**** CARLA STECCO(*) - GIUSEPPE DODI ... 12. Juricic M, Vaysse P, Guitard J, Moscovici J. Anatomic bases for use of a gracilis muscle flap. ...

Research paper thumbnail of Vascular and Interventional Imaging: Case Review Series, 2nd ed

American Journal of Roentgenology, 2011

Research paper thumbnail of Anatomical study of renal arterial vasculature and its potential impact on partial nephrectomy

BJUI, Feb 20, 2017

To validate Graves' classification of the intrarenal arteries and to verify the absence of collat... more To validate Graves' classification of the intrarenal arteries and to verify the absence of collateral arterial blood supply between different renal segments, in order to maximize peri-operative and functional outcomes of partial nephrectomy. Materials and Methods The study was performed on 15 normal kidneys sampled from eight unembalmed cadavers. Kidneys with the surrounding perirenal fat tissue were removed en bloc with the abdominal segment of the aorta. The renal artery was injected with acrylic and radiopaque resins, with the specimen suspended in water. CT examination of the injected kidneys was performed to analyse the branches located deeply. After imaging acquisition, the specimens were treated with sodium hydroxide for removal of the parenchyma to obtain vascular casts. Results Ten casts (66.6%) showed the classic subdivision of the main artery into single posterior and anterior branches. With regard to the distribution of the segmental or second-order arteries, only two casts (13%) showed a pattern similar to that described by Graves, characterized by four segmental (secondorder) branches coming from the anterior renal artery (apical, superior, middle and inferior). In the remaining 13 kidneys (87%) a different arterial vascular network was detected. In 10 casts (80%) a single renal segment was vascularized by two or more different branches coming from an artery leading to another segment (multiple vascularization). Multiple vascularization was observed in three (20%) apical segments, five (33%) superior segments, six (40%) middle segments, seven (47%) inferior segments and two (13%) posterior segments. Conclusions This study shows that in the human kidneys the arterial vasculature is frequently different from that described by Graves. Moreover, in a significant percentage of cases, a single renal segment receives two or more branches that originate from an artery leading to another segment.

Research paper thumbnail of Double origin of the superior cerebellar artery associated with homolateral haemorrhagic infarction of cerebellum

Folia Neuropathologica, 2016

The superior cerebellar artery (SCA) shows the least variable course and the lowest incidence of ... more The superior cerebellar artery (SCA) shows the least variable course and the lowest incidence of anatomical variations among cerebellar arteries. In the present study, an 84-year-old woman was affected by a cerebellar infarction which underwent haemorrhagic evolution in the following days. Neuroimaging investigations also showed a probable double origin of the left SCA. Neuropathological examination confirmed the presence of a large haemorrhagic infarction at the level of the superior portion of the left cerebellar hemisphere and vermis. The left SCA arose from two small arteries arising from the left aspect of the basilar artery and joining together after a course of 9 mm. Previous studies have reported the association of cerebrovascular pathologies, such as intracranial aneurysms, with fenestrations and double origins of the posterior inferior cerebellar artery. In the present case, the occurrence of an haemorrhagic infarction in the vascular field of an SCA with double origin is intriguing in suggesting a possible pathophysiological association.