Alexandru Nicolae Popescu - Academia.edu (original) (raw)
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Papers by Alexandru Nicolae Popescu
The zoonosis according to The Health World Organization, are defined as being “diseases or infect... more The zoonosis according to The Health World Organization, are defined as being “diseases or infections which are naturally transmitted between the vertebrate animal and man” but this definition is still submissive of some wide debates. The close cohabitation of people with their animals in large areas of the world, often in inadequate conditions, continues to favor the zoonotic infections. The dogs and cats population as pets increased in the whole world. The danger of this kind of zoonotic diseases is increasing, but national and local settlements have been promulgated to establish the places where animals can be accepted and to prevent the environment pollution
Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Horticulture, 2008
Alimentary toxiinfections produced by Salmonella from view point of frequency and hygienic-sanita... more Alimentary toxiinfections produced by Salmonella from view point of frequency and hygienic-sanitary implications are on the first place in most of countries. At animals the infection is maintained by recycling the waste from slaughterhouses as food for animals, fecal-oral transmission, and fecal contaminations of eggs. They are widely distributed in nature, with humans and animals being their primary reservoirs. All salmonellae have been placed in two species, S. enterica and S. bongori with 2,500 or so serovars being divided into 5 species or groups, most of which are classified under S. enterica, the type species. The major groups correspond to the following subspecies: group II (S. enterica subsp. salamae), group III a (S. enterica subsp. arizonae), group III b (S. enterica subsp. diarizonae); group IV (S. enterica subsp. houtenae); and group VI (S. enterica subsp. indica). The former group V organisms have been elevated to species status as S. bongori. Objective: Study regarding...
Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Veterinary Medicine, 2008
Leptospirosis is an acute antropozoonosis characterized by fever, shivers, myalgia, meningeal, he... more Leptospirosis is an acute antropozoonosis characterized by fever, shivers, myalgia, meningeal, hepatic and renal disturbances, the disease has an universal dissemination with an sporadic endemic course on which limited epidemies graft, especially during summer and autumn and in rural environment. The disease has also a professional character, occurring especially in those who work with animals or in marshy environments. The males are more frequently affected by it. As for the situation of human leptospirosis in Romania, several particular aspects must be taken into account: the atypical and the subclinical types remain non-diagnosed, because they are not noticed by the patients or are considered to be intercurrent diseases, but they can develop serious latent infections; due to the lack of systematic deratizations, at the level of the entire country, an increase of the number of sporadic cases is registered and consequently also an increase of the number of those with a fatal course.
Scientific Works - University of Agronomical Sciences and Veterinary Medicine, Bucharest. Series C, Veterinary Medicine, 2012
In recent years, a considerable effort was dedicated to researching methylxantine derivatives (MX... more In recent years, a considerable effort was dedicated to researching methylxantine derivatives (MX), because of their effect on the hemorheology, increasing deformability, decreasing the aggregation trend of the red blood cells and the fibrinogen concentration. All of these properties turned MX into a drug eligible to be in peripheral and cerebral vascular disorders. At the same time, the pharmacological profile of MX and their short half-life make it a good candidate for encapsulation of drugs. Lipid nanostructures are a new technology for the encapsulation and delivery of bioactive agents. Because of their biocompatibility and biodegradability, along with their nanosizes, they have potential applications in a vast range of fields. They are able to improve the solubility, bioavailability and stability of bioactive agents, to provide protection of drugs and as well to prevent their unwanted interactions with other molecules, to ensure cellspecific targeting, to minimize adverse effec...
Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Veterinary Medicine, 2010
A number of 103 ownerless dogs, not vaccinated against leptospirosis, accommodated at the testing... more A number of 103 ownerless dogs, not vaccinated against leptospirosis, accommodated at the testing moment in a community shelter in Bucharest, are tested for leptospirosis by the ultramicroscopic agglutination seroreaction with MAR (microagglutination reaction-type) type live antigen. The results revealed that 36,89% of these dogs represent for humans and for domestic and farm animals a potential natural reservoir of infection with microorganisms of the Lesptospira genus. The Canicola serotype was identified in 81,57% of the positive cases and the Icterohaemorrhagiae serotype in 18,43% of the positive cases.
Journal of Biotechnology, 2014
The zoonosis according to The Health World Organization, are defined as being “diseases or infect... more The zoonosis according to The Health World Organization, are defined as being “diseases or infections which are naturally transmitted between the vertebrate animal and man” but this definition is still submissive of some wide debates. The close cohabitation of people with their animals in large areas of the world, often in inadequate conditions, continues to favor the zoonotic infections. The dogs and cats population as pets increased in the whole world. The danger of this kind of zoonotic diseases is increasing, but national and local settlements have been promulgated to establish the places where animals can be accepted and to prevent the environment pollution
Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Horticulture, 2008
Alimentary toxiinfections produced by Salmonella from view point of frequency and hygienic-sanita... more Alimentary toxiinfections produced by Salmonella from view point of frequency and hygienic-sanitary implications are on the first place in most of countries. At animals the infection is maintained by recycling the waste from slaughterhouses as food for animals, fecal-oral transmission, and fecal contaminations of eggs. They are widely distributed in nature, with humans and animals being their primary reservoirs. All salmonellae have been placed in two species, S. enterica and S. bongori with 2,500 or so serovars being divided into 5 species or groups, most of which are classified under S. enterica, the type species. The major groups correspond to the following subspecies: group II (S. enterica subsp. salamae), group III a (S. enterica subsp. arizonae), group III b (S. enterica subsp. diarizonae); group IV (S. enterica subsp. houtenae); and group VI (S. enterica subsp. indica). The former group V organisms have been elevated to species status as S. bongori. Objective: Study regarding...
Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Veterinary Medicine, 2008
Leptospirosis is an acute antropozoonosis characterized by fever, shivers, myalgia, meningeal, he... more Leptospirosis is an acute antropozoonosis characterized by fever, shivers, myalgia, meningeal, hepatic and renal disturbances, the disease has an universal dissemination with an sporadic endemic course on which limited epidemies graft, especially during summer and autumn and in rural environment. The disease has also a professional character, occurring especially in those who work with animals or in marshy environments. The males are more frequently affected by it. As for the situation of human leptospirosis in Romania, several particular aspects must be taken into account: the atypical and the subclinical types remain non-diagnosed, because they are not noticed by the patients or are considered to be intercurrent diseases, but they can develop serious latent infections; due to the lack of systematic deratizations, at the level of the entire country, an increase of the number of sporadic cases is registered and consequently also an increase of the number of those with a fatal course.
Scientific Works - University of Agronomical Sciences and Veterinary Medicine, Bucharest. Series C, Veterinary Medicine, 2012
In recent years, a considerable effort was dedicated to researching methylxantine derivatives (MX... more In recent years, a considerable effort was dedicated to researching methylxantine derivatives (MX), because of their effect on the hemorheology, increasing deformability, decreasing the aggregation trend of the red blood cells and the fibrinogen concentration. All of these properties turned MX into a drug eligible to be in peripheral and cerebral vascular disorders. At the same time, the pharmacological profile of MX and their short half-life make it a good candidate for encapsulation of drugs. Lipid nanostructures are a new technology for the encapsulation and delivery of bioactive agents. Because of their biocompatibility and biodegradability, along with their nanosizes, they have potential applications in a vast range of fields. They are able to improve the solubility, bioavailability and stability of bioactive agents, to provide protection of drugs and as well to prevent their unwanted interactions with other molecules, to ensure cellspecific targeting, to minimize adverse effec...
Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Veterinary Medicine, 2010
A number of 103 ownerless dogs, not vaccinated against leptospirosis, accommodated at the testing... more A number of 103 ownerless dogs, not vaccinated against leptospirosis, accommodated at the testing moment in a community shelter in Bucharest, are tested for leptospirosis by the ultramicroscopic agglutination seroreaction with MAR (microagglutination reaction-type) type live antigen. The results revealed that 36,89% of these dogs represent for humans and for domestic and farm animals a potential natural reservoir of infection with microorganisms of the Lesptospira genus. The Canicola serotype was identified in 81,57% of the positive cases and the Icterohaemorrhagiae serotype in 18,43% of the positive cases.
Journal of Biotechnology, 2014