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Papers by Alfarghal Mohamad

Research paper thumbnail of Identification of vestibular loss in children with sensorineural hearing loss using the balance subset of the BOT-2 test

The Egyptian Journal of Otolaryngology, Oct 23, 2023

Background Vestibular loss in children with sensorineural hearing loss (SNHL) is quite high. Desp... more Background Vestibular loss in children with sensorineural hearing loss (SNHL) is quite high. Despite the high prevalence of vestibular loss and balance impairment in children with SNHL, they are rarely assessed by clinicians and therefore are commonly undiagnosed. The purpose of the study was to evaluate the balance subset of the Bruininks-Oseretsky Test (BOT-2) as a tool to identify vestibular loss in children with SNHL and to determine its predictive values for vestibular loss. Methods The study included 210 children allocated into 4 groups: group 1 (control healthy children), group II (children with SNHL but without vestibular loss), group III (children with SNHL and unilateral vestibular loss), and group IV (children with SNHL and bilateral vestibular loss). Caloric test, video head impulse test (vHIT), and cervical vestibular evoked myogenic potential (c-VEMP) test were used for vestibular assessment in children with SNHL and to allocate them accordingly into one of the aforementioned groups. Scores of the balance subset of the BOT-2 were compared among the three groups and compared to the control healthy children. Results 21.4% of children with SNHL but without vestibular loss have balance deficit revealed by the balance subset of the BOT-2, reflecting its better sensitivity for detecting balance deficit than the physiologic vestibular tests. Children with unilateral or bilateral vestibular loss (groups III and IV) showed a more significant balance deficit than children without vestibular loss (group II). The worst balance score was found in children with bilateral vestibular loss. The positive predictive value of the BOT-2 for peripheral vestibular loss in children with SNHL was 88%. Conclusion The balance subset of the BOT-2 has particularly good predictive values for vestibular loss in children with SNHL. The test is a simple, easy, fast office test which does not require any costly equipment.

Research paper thumbnail of Chronic symptoms in patients with unilateral vestibular hypofunction: systematic review and meta-analysis

Frontiers in Neurology

ObjectiveTo systematically evaluate the full spectrum of self-reported chronic symptoms in patien... more ObjectiveTo systematically evaluate the full spectrum of self-reported chronic symptoms in patients with unilateral vestibular hypofunction (UVH) and to investigate the effect of interventions on these symptoms.MethodsA systematic review was conducted following the guidelines of the Preferred Reporting Items for Systematic Review and Meta-Analysis Statement (PRISMA). A literature search was performed in Pubmed, Web of Science, Embase, and Scopus to investigate self-reported symptoms and self-report questionnaires in patients with UVH. All original studies ranging from full-text clinical trials to case reports, written in English, German, and French, were included. The frequency of self-reported symptoms was presented. For self-report questionnaires, a meta-analysis was carried out to synthesize scale means by the pre- and post-intervention means and mean changes for studies that investigated interventions.ResultsA total of 2,110 studies were retrieved. Forty-seven studies were inclu...

Research paper thumbnail of The validity of Arabic version of Vestibular Disorder Activities of Daily Living Scale in common episodic vestibular disorders during and in between the attacks: a cross-sectional study

The Egyptian Journal of Otolaryngology

Background Activities of daily living (ADLs) are activities oriented toward taking care of one’s ... more Background Activities of daily living (ADLs) are activities oriented toward taking care of one’s own body independently. Vestibular Disorder Activities of Daily Living Scale (VADL) includes 28 questions designed to specifically assess the effects of different vestibular disorders on activities of daily living and assess the validity and reliability of the Arabic version of VADL and applying it to assess severity of the attacks related to most common episodic vestibular disorders. The Arabic version of VADL was distributed to 52 participants, recruiting two participants per question. The participants filled up the Arabic version of VADL scale, in-between and during the vertigo episodes. Results All participants have been diagnosed as having one of these vestibular disorders benign paroxysmal positional vertigo (BPPV), vestibular migraine, and Meniere’s disease. The reliability analysis was calculated with Cronbach’s alpha score, and it was 0.980, indicating high reliability. There wa...

Research paper thumbnail of Benign Paroxysmal Positional Vertigo Involving Multiple Canals

BPPV is the most common cause of peripheral vertigo, with one year prevalence of 1.6%. It is a me... more BPPV is the most common cause of peripheral vertigo, with one year prevalence of 1.6%. It is a mechanical labyrinthine disorder, characterized by recurrent brief, intense vertiginous attacks provoked by head position changes with respect to gravity. Each attack usually lasts for 15 to 60 seconds. It usually has a favorable course that is why it is defined as “Benign”, however it sometimes become a disabling condition which affects the patient’s quality of life.

Research paper thumbnail of Effects of Menstrual Cycles on VOR Gain Functions

Annals of Otology and Neurotology, 2021

Purpose The aim of the present study was to assess the vestibuloocular reflex (VOR) gain function... more Purpose The aim of the present study was to assess the vestibuloocular reflex (VOR) gain function and VOR gain asymmetry during the various phases of the menstrual cycle in young healthy female participants. The study also aimed to characterize the presence or absence of corrective saccades during the various phases of the menstrual cycle. Method Twenty-nine young healthy females participated in the study. The video head impulse test (vHIT) was performed in lateral, left anterior right posterior, and right anterior left posterior plane during the various phases of the menstrual cycle to see the changes in VOR gain function and VOR gain asymmetry ratio changes. Results A repeated measure analysis of variance test did not show any significant main effect for the VOR gain function and VOR gain asymmetry ratio in various phases of the menstrual cycle in all the participants. The result suggested no changes in VOR gain function and VOR asymmetry ratio in healthy females during the menstr...

Research paper thumbnail of Complex Forms of Benign Paroxysmal Positional Vertigo

Research paper thumbnail of Benign Paroxysmal Positional Vertigo Involving Multiple Canals

Global Journal of Otolaryngology, Sep 26, 2017

Research paper thumbnail of Wernicke's Encephalopathy, A Curable Cause of Acute Bilateral Vestibulopathy

Global Journal of Otolaryngology

Research paper thumbnail of Bilateral Conductive Hearing Loss due to Collapsed Ear Canals in a 35 Years Old Female

Journal of Otolaryngology-ENT Research

Research paper thumbnail of Identification of vestibular loss in children with sensorineural hearing loss using the balance subset of the BOT-2 test

The Egyptian Journal of Otolaryngology, Oct 23, 2023

Background Vestibular loss in children with sensorineural hearing loss (SNHL) is quite high. Desp... more Background Vestibular loss in children with sensorineural hearing loss (SNHL) is quite high. Despite the high prevalence of vestibular loss and balance impairment in children with SNHL, they are rarely assessed by clinicians and therefore are commonly undiagnosed. The purpose of the study was to evaluate the balance subset of the Bruininks-Oseretsky Test (BOT-2) as a tool to identify vestibular loss in children with SNHL and to determine its predictive values for vestibular loss. Methods The study included 210 children allocated into 4 groups: group 1 (control healthy children), group II (children with SNHL but without vestibular loss), group III (children with SNHL and unilateral vestibular loss), and group IV (children with SNHL and bilateral vestibular loss). Caloric test, video head impulse test (vHIT), and cervical vestibular evoked myogenic potential (c-VEMP) test were used for vestibular assessment in children with SNHL and to allocate them accordingly into one of the aforementioned groups. Scores of the balance subset of the BOT-2 were compared among the three groups and compared to the control healthy children. Results 21.4% of children with SNHL but without vestibular loss have balance deficit revealed by the balance subset of the BOT-2, reflecting its better sensitivity for detecting balance deficit than the physiologic vestibular tests. Children with unilateral or bilateral vestibular loss (groups III and IV) showed a more significant balance deficit than children without vestibular loss (group II). The worst balance score was found in children with bilateral vestibular loss. The positive predictive value of the BOT-2 for peripheral vestibular loss in children with SNHL was 88%. Conclusion The balance subset of the BOT-2 has particularly good predictive values for vestibular loss in children with SNHL. The test is a simple, easy, fast office test which does not require any costly equipment.

Research paper thumbnail of Chronic symptoms in patients with unilateral vestibular hypofunction: systematic review and meta-analysis

Frontiers in Neurology

ObjectiveTo systematically evaluate the full spectrum of self-reported chronic symptoms in patien... more ObjectiveTo systematically evaluate the full spectrum of self-reported chronic symptoms in patients with unilateral vestibular hypofunction (UVH) and to investigate the effect of interventions on these symptoms.MethodsA systematic review was conducted following the guidelines of the Preferred Reporting Items for Systematic Review and Meta-Analysis Statement (PRISMA). A literature search was performed in Pubmed, Web of Science, Embase, and Scopus to investigate self-reported symptoms and self-report questionnaires in patients with UVH. All original studies ranging from full-text clinical trials to case reports, written in English, German, and French, were included. The frequency of self-reported symptoms was presented. For self-report questionnaires, a meta-analysis was carried out to synthesize scale means by the pre- and post-intervention means and mean changes for studies that investigated interventions.ResultsA total of 2,110 studies were retrieved. Forty-seven studies were inclu...

Research paper thumbnail of The validity of Arabic version of Vestibular Disorder Activities of Daily Living Scale in common episodic vestibular disorders during and in between the attacks: a cross-sectional study

The Egyptian Journal of Otolaryngology

Background Activities of daily living (ADLs) are activities oriented toward taking care of one’s ... more Background Activities of daily living (ADLs) are activities oriented toward taking care of one’s own body independently. Vestibular Disorder Activities of Daily Living Scale (VADL) includes 28 questions designed to specifically assess the effects of different vestibular disorders on activities of daily living and assess the validity and reliability of the Arabic version of VADL and applying it to assess severity of the attacks related to most common episodic vestibular disorders. The Arabic version of VADL was distributed to 52 participants, recruiting two participants per question. The participants filled up the Arabic version of VADL scale, in-between and during the vertigo episodes. Results All participants have been diagnosed as having one of these vestibular disorders benign paroxysmal positional vertigo (BPPV), vestibular migraine, and Meniere’s disease. The reliability analysis was calculated with Cronbach’s alpha score, and it was 0.980, indicating high reliability. There wa...

Research paper thumbnail of Benign Paroxysmal Positional Vertigo Involving Multiple Canals

BPPV is the most common cause of peripheral vertigo, with one year prevalence of 1.6%. It is a me... more BPPV is the most common cause of peripheral vertigo, with one year prevalence of 1.6%. It is a mechanical labyrinthine disorder, characterized by recurrent brief, intense vertiginous attacks provoked by head position changes with respect to gravity. Each attack usually lasts for 15 to 60 seconds. It usually has a favorable course that is why it is defined as “Benign”, however it sometimes become a disabling condition which affects the patient’s quality of life.

Research paper thumbnail of Effects of Menstrual Cycles on VOR Gain Functions

Annals of Otology and Neurotology, 2021

Purpose The aim of the present study was to assess the vestibuloocular reflex (VOR) gain function... more Purpose The aim of the present study was to assess the vestibuloocular reflex (VOR) gain function and VOR gain asymmetry during the various phases of the menstrual cycle in young healthy female participants. The study also aimed to characterize the presence or absence of corrective saccades during the various phases of the menstrual cycle. Method Twenty-nine young healthy females participated in the study. The video head impulse test (vHIT) was performed in lateral, left anterior right posterior, and right anterior left posterior plane during the various phases of the menstrual cycle to see the changes in VOR gain function and VOR gain asymmetry ratio changes. Results A repeated measure analysis of variance test did not show any significant main effect for the VOR gain function and VOR gain asymmetry ratio in various phases of the menstrual cycle in all the participants. The result suggested no changes in VOR gain function and VOR asymmetry ratio in healthy females during the menstr...

Research paper thumbnail of Complex Forms of Benign Paroxysmal Positional Vertigo

Research paper thumbnail of Benign Paroxysmal Positional Vertigo Involving Multiple Canals

Global Journal of Otolaryngology, Sep 26, 2017

Research paper thumbnail of Wernicke's Encephalopathy, A Curable Cause of Acute Bilateral Vestibulopathy

Global Journal of Otolaryngology

Research paper thumbnail of Bilateral Conductive Hearing Loss due to Collapsed Ear Canals in a 35 Years Old Female

Journal of Otolaryngology-ENT Research