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Research Papers by Alice Branton

Exploring the Therapeutic Potentials of Nonpharmacological Blessing Energy Intervention for the Benefits of Psycho-Mental Impaired Individuals: A Clinical Trial, Mar 12, 2025

Background: In traditional healing systems, life-force energy or subtle human energy fields have ... more Background: In traditional healing systems, life-force energy or subtle human energy fields have been recognized
for millennia. Parallel to conventional therapy, its popularity has grown tremendously in recent years.
Due to limited scientific research on biofield therapies, the authors investigated the potential impact of distant
biofield/blessing energy interventions on individuals with psychological impairments via virtual
methods.
Methods: A total of 119 participants (56 male, 63 female) with one or more psycho-mental symptoms were
enrolled in these randomized, placebo-controlled, double-blind clinical trials. Two remote biofield/blessing
energy interventions, each lasting approximately 5 min, were delivered to 38 subjects in the biofield intervention
group on days 0 and 90. Subjects were assessed using standardized psychological questionnaires, which
employed a validated scoring scale, as well as safety parameters.
Results: Participants in the biofield (blessing) intervention group reported significantly lower levels of perceived
psychological symptoms (fatigue, sleep disturbances, stress, cognitive impairment, and emotional distress)
compared with both naive and sham control groups (p < 0.0001). Biofield intervention was safe and
well-tolerated in all three groups.
Conclusion: Distant biofield/blessing energy healing sessions were found to significantly improve psychological
and mental health, enhance overall well-being, and pose no safety risks. Therefore, further research is needed to
identify key variables for a larger scale intervention study on health outcomes and underlying mechanisms.
Trial registration: Clinical Trials Registry Number—India (CTRI/2022/07/043633).

Alternative Therapies in Health and Medicine, Feb 3, 2025

Background: Biofield therapies like Reiki, blessing, and healing touch are non-invasive technique... more Background: Biofield therapies like Reiki, blessing, and healing touch are non-invasive techniques that aim to enhance well-being—mental, emotional, and physical. They can be conducted both in-person and remotely. However, a literature review found no evidence of distant/remote blessing therapy’s effectiveness in improving mental health symptoms in adults.

Primary Study Objective: To evaluate the safety and effectiveness of non-pharmacological distant blessing (biofield energy healing) therapy for psychological and mental health management.

Methods/Design: One hundred seventeen participants with psychological symptoms were studied. On days 0 and 90, the biofield (blessing) therapy group (n = 38) received two sessions of distant blessing energy therapy, each lasting about 5 minutes. A sham control group (n = 40) received similar treatment from a sham practitioner to nullify the baseline responses, while a control group (n = 39) received no intervention. Participants were assessed using a standard psychological questionnaire and safety parameters.

Setting: A placebo-controlled, three parallel groups, single-center, double-blinded, and randomized controlled trial.

Participants: Adult human subjects (male and female) with one or more psychological symptoms.

Intervention: Distant (remote) biofield energy healing/blessing therapy.

Primary outcome measures: Psychological questionnaires scoring.

Results: Perceived psychological symptoms/scores (fatigue/tiredness, sleep disturbances, stress, cognitive impairment, loss of memory, mental restlessness, emotional trauma, anxiety, depression, confusion, lack of relationships, and social behaviors) were significantly improved in the blessing group compared to control and sham control groups (P < .0001). Study intervention did not show any study-related adverse effects in all three groups throughout the trial.

Conclusion: The findings from this study suggest that distant (remote) blessing therapy/biofield energy healing session(s) significantly improved psychological and mental health-related symptoms without affecting safety concerns and improved overall health and quality of life. Therefore, the present study recommends a larger-scale intervention study to further investigate various health outcomes and this therapy’s underlying mechanisms of action.

Trial registration: The trial was registered in the Clinical Trials Registry – India (Reg. no. CTRI/2022/07/043736) dated 05/07/2022.

Effectiveness of Distant/Remote Blessing Treatment on Cognitive-motor Function: A Randomized Double-blind Placebo-controlled Trial, Jan 16, 2025

"Background Biofield therapies can be administered in person (hands-on treatment) or remotely, an... more "Background
Biofield therapies can be administered in person (hands-on treatment) or remotely, and this study focuses on the latter. A literature review did not find any reports on the effectiveness of remote biofield energy /blessing therapy in enhancing cognition and motor function performance in adults.

Objective
The aim of this study was to examine the effect of distant/remote blessing (biofield energy) therapy on the cognitive and motor functions in adults with self-reported neuropsychological impairments using NIH Toolbox®.

Methods
The present study was a randomized, double-blind clinical trial involving 117 participants with self-reported neuropsychological impairments. These participants were stratified into three distinct groups: control, sham control, and blessing/biofield treatment as the intervention. At baseline (day 0), day 90, and day 180, NIH Toolbox® was employed to evaluate all participants’ cognitive and motor function scores.

Results
In the blessing treatment group, language function score (p <0.01), working memory (p <0.0001), and episodic memory (p <0.0001) scores exhibited statistically significant differences compared to both the naïve control and sham control groups. Moreover, in the blessing intervention group, a substantial improvement was observed in locomotion (p <0.0001), standing balance (p <0.01), dexterity (p <0.01), grip strength (p <0.05), and muscle endurance (p <0.05) compared to the naïve control and sham control groups. Importantly, no adverse effects were reported during the study period.

Conclusion
The study outcomes revealed that distant/remote blessing/biofield energy therapy is safe, non-invasive, and less expensive. It enhances cognitive-motor functions in adults with perceived neuropsychological impairments.

Clinical Trial Registration
CTRI/2022/07/043736."

Cannabidiol (CBD) Upregulates Vitamin D3 Receptors (VDRs) Expression That Modulates Cytokines (TNF-α, IL-6), Tissue Elasticity, Cellular Senescence, and Mitochondrial ATP Generation in Human and Rodent Cell Lines, Nov 6, 2023

"""Background Cannabidiol (CBD) is a non-psychoactive cannabinoid derived from Cannabis sativa L.... more """Background
Cannabidiol (CBD) is a non-psychoactive cannabinoid derived from Cannabis sativa L. with very low toxicity for human and a wide variety of therapeutic uses as medicine. The study objective is to evaluate the impact of CBD on vitamin D3 receptor (VDR) protein expressions, tissue elasticity, anti-inflammatory, and anti-senescence activity in human and rodent cell lines.

Methods
Cell viability was estimated by MTT assay. Relative quantification (RQ) of VDR protein expression was measured by RT-PCR. Tissue elasticity was measured by atomic force microscopy (AFM). Cellular senescence and ATP were performed using trypan blue exclusion test and colorimetric assay, respectively.

Results
Cell viability assay data showed CBD was safe and nontoxic upto 7.5 µM. The VDR protein expression was significantly increased by 109.71% (p = 0.013), 236.96% (p ≤ 0.001), 170% (p ≤ 0.001), 100% (p = 0.019), 80% (p = 0.021), 427.27% (p ≤ 0.001), 366.67% (p ≤ 0.001), 56.31% (p = 0.016), and 63.84% (p ≤ 0.001) in MG-63, MDA-MB-231, SH-SY5Y, HEK-293, HT-29, EaHy-926, HepG2, A-549, and C2C12 cells, respectively compared to the normal control group. CBD treatment significantly reduced the levels of TNF-α (46.58%; p ≤ 0.049) and IL-6 (43.61%; p ≤ 0.001) at CBD-5 µM compared to the vehicle control group. Tissue elasticity was significantly (p ≤ 0.001) increased by 37.09% and 49.49% in CBD-2.5 and CBD-5 µM, respectively, compared to the vehicle control group. Significantly (p ≤ 0.001) reduced senescence cells by 39.22% in CBD-5 µM than the vehicle control group. The level of ATP was significantly (p ≤ 0.001) increased by 90.55, 117.06, and 153.54% in CBD-1, CBD-2.5, and CBD-5 µM, respectively, compared to the vehicle control group.

Conclusion
Overall, data suggest that CBD considerably improved VDR protein expression, inflammation, cell growth, tissue elasticity, and enhanced mitochondrial bioenergetics in multiple cell lines. In this study, for the first time, we showed the evidence suggesting that the VDR plays a critical and multifaceted role in various types of human cells."""

Assessment of cognitive–motor functions in adults with perceived neuropsychological problems using NIH toolbox after remote biofield energy treatment as non-pharmacological intervention: A randomized double-blind placebo controlled trial, Sep 13, 2024

Non-pharmacological interventions include physical activity, biofield energy therapy, reiki, Tai ... more Non-pharmacological interventions include physical activity, biofield energy therapy, reiki, Tai chi, and therapeutic touch. However, no reports analyzed the effectiveness of biofield therapy on cognition and motor function performance in adult subjects. The study aimed to investigate the impact of remote biofield energy healing therapy on cognition and motor functioning in adults with self-perceived neuropsychological impairments. This was a randomized double-blind clinical trial that involved 114 participants with self-perceived neuropsychological impairments. The participants were divided into three groups (control, sham control, and biofield intervention). Cognitive and motor function scores were assessed using the NIH Toolbox at baseline (day 0), day 90, and day 180. The biofield treatment group showed significant improvements in language function (p < 0.0001), working memory (p < 0.0001), and episodic memory (p < 0.0001) scores. Other cognitive functions also improved, although not statistically significant. The biofield intervention group also demonstrated significant enhancements (p < 0.05 to p < 0.0001) in locomotion, standing balance, dexterity, grip strength, and muscle endurance. No adverse effects were reported. The results suggest that remote biofield energy therapy is a safe, noninvasive intervention that improves cognitive and motor functions in adults. Further research is needed to understand its clinical benefits.

The Improvement of Cognitive-Motor Function Scores Using the NIH-Toolbox in Adults Subjects After Biofield Energy Therapy: A Randomized Controlled Double-blind Trial

The Improvement of Cognitive-Motor Function Scores Using the NIH-Toolbox in Adults Subjects After Biofield Energy Therapy: A Randomized Controlled Double-blind Trial, Aug 30, 2024

"Abstract Background: There is a growing interest for the use of an alternative treatment approac... more "Abstract
Background: There is a growing interest for the use of an alternative treatment approach like biofield energy therapy for managing various diseases. However, the effectiveness of distance mode of biofield energy therapy on neuropsychological function has not been examined so far.

Primary study objective: The study was aimed to evaluate the effect of biofield energy therapy via distant mode for the benefits of neuropsychological functions in adult subjects.

Methods: It comprised of three parallel groups (control, sham control, and biofield intervention). The cognitive-motor functioning scores were monitored using NIH-Toolbox in 119 adult subjects on day 0, day 90, and day 180.

Setting: Double-blind, single-center, randomized controlled trial (RCT).

Participants: Adult human subjects (male and female) with one or more psychological symptoms.

Intervention: Biofield energy therapy through distant/remote (virtual) mode.

Primary outcome measures: The cognitive-motor functioning scores.

Results: The cognitive-motor functioning scores were significantly improved in the biofield intervention group compared to the control and sham control groups: cognition- language (P < .0057 to P < .0001), working memory (P < .0001), episodic memory function (P < .0369 to P < .0001), and executive function (P < .0386 to P < .0029); motor- locomotion P < .0001), standing balance (P = .0144 to P = .0019), dexterity (P = .0474 to P < .0001), grip strength (P = .0132 to P = .0078) and endurance (P = .0041 to P = .0004). No adverse effects were observed throughout the study. Physical vital signs and blood parameters were within the normal ranges during the entire study period.

Conclusions: Overall, cognitive and motor functions significantly improved in the blessing intervention group compared to the naïve control and sham control groups, which ultimately improved the neuropsychological function and quality of life in adult subjects."

Effects of distant biofield energy healing on adults associated with psychological and mental health-related symptoms: a randomized, placebo-controlled, double-blind study, Aug 14, 2024

"Background In recent years, popularity of Biofield energy healing therapy has increased tremendo... more "Background
In recent years, popularity of Biofield energy healing therapy has increased tremendously parallel to conventional therapy. However, due to insufficient scientific studies on biofield therapies, authors planned this clinical trial to examine the safety and effectiveness of biofield therapy in treating symptoms of psychological and mental health and to explore parameters for its effectiveness.

Methods
One hundred fourteen participants (55 male, 59 female) underwent clinical trials. This trial was randomized, placebo-controlled, three parallel-groups, double-blind, and single-center with subjects who have one or more psychological and mental symptoms. Two sessions of distant (virtual) biofield energy attunement were given on days 0 and 90 for about 5 minutes to the subjects of biofield intervention group (n=39). Besides, control (n=35) and sham control (n=40) group subjects also received kind of treatment in a similar manner to nullify baseline responses. Subjects were assessed by psychological questionnaire scoring using standard scale of assessment and safety parameters.

Results
Perceived psychological symptoms/scores (fatigue/tiredness, sleep disturbances, stress, cognitive impairment, loss of memory, mental restlessness, emotional trauma, anxiety, depression, confusion, financial crises and dissatisfaction, low libido, motivation, confidence, lack of perception, relationship, and social behaviors, etc.) were significantly (p <.0001) improved in biofield intervention group compared to the naïve control and sham control groups. Besides, biofield intervention did not show any study-related adverse effects in all three groups throughout the trial.

Conclusions
The distant (virtual) biofield energy healing therapy significantly improved psychological and mental health-related symptoms without affecting safety concerns, and improved overall health and quality of life."

The use of biofield energy therapy as complementary and alternative medicine in human health care system: a narrative review and potential mechanisms

The use of biofield energy therapy as complementary and alternative medicine in human health care system: a narrative review and potential mechanisms, Apr 3, 2024

Introduction There has been accumulating interest in the application of biofield therapy as comp... more Introduction
There has been accumulating interest in the application of biofield therapy as complementary and alternative medicine (CAM) to treat various diseases. The practices include reiki, qigong, blessing, prayer, distant healing, known as biofield therapies. This paper aims to state scientific knowledge on preclinical and clinical studies to validate its potential use as an alternative medicine in the clinic. It also provides a more in-depth context for understanding the potential role of quantum entanglement in the effect of biofield energy therapy.

Content
A comprehensive literature search was performed using the different databases (PubMed, Scopus, Medline, etc.). The published English articles relevant to the scope of this review were considered. The review gathered 45 papers that were considered suitable for the purpose. Based on the results of these papers, it was concluded that biofield energy therapy was effective in treating different disease symptoms in preclinical and clinical studies.

Summary
Biofield therapies offer therapeutic benefits for different human health disorders, and can be used as alternative medicine in clinics for the medically pluralistic world due to the growing interest in CAM worldwide.

Outlook
The effects of the biofield energy therapies are observed due to the healer’s quantum thinking, and transmission of the quantum energy to the subject leads to the healing that occurs spiritually through instantaneous communication at the quantum level via quantum entanglement.

Identification of Endothelin-1 and Nitric Oxide Activity in Aorta, Lung and Kidney after Treatment with the Biofield Energy Treated Proprietary Test Formulation on L-Name and High Fat Diet-Induced Cardiovascular Disorders in Sprague Dawley Rats, Sep 6, 2021

The study was aimed to investigate the impact of the Trivedi Effect® on high fat diet (HFD) and N... more The study was aimed to investigate the impact of the Trivedi Effect® on high fat diet (HFD) and NG-nitro-L-arginine methyl ester hydrochloride (L-NAME)-induced Sprague Dawley rats using various functional organ (aorta, lung, and kidney) biomarkers. The functional biomarkers like endothelin-1 and nitric oxide (NO) were evaluated in all the three tissue homogenate using ELISA. The proprietary test formulation including minerals (selenium, magnesium, zinc, calcium, iron, and copper), vitamins (vitamin B9, ascorbic acid, cyanocobalamin, cholecalciferol, and pyridoxine HCl), cannabidiol isolate, β-carotene, and Panax ginseng extract. The each constituents of the proprietary test formulation were divided into two parts; one was denoted as untreated without any Blessing, while the other part received Biofield Treatment by Mr. Mahendra Kumar Trivedi. The results showed that the level of endothelin-1 in the aorta tissue homogenate was decreased by 52.41%, 50.92%, 42.71%, 32.20%, and 45.66% in the G5, G6, G7, G8, and G9 groups, respectively than disease control (G2) group. The level of NO in the aorta tissue homogenate was increased by 30.77%, 11.02%, 13.96%, and 22.57% in the G5, G6, G7, and G8 than G2. Moreover, the expression of endothelin-1 in the lung tissue homogenate was decreased by 40.95%, 19.69%, 39.94%, 24.09%, and 18.85% in the G5, G6, G7, G8, and G9 groups, respectively than G2. The level of NO in the lung tissue homogenate was increased by 25.29% and 29.16% in the G6 and G7 groups, respectively than G2. Further, the level of endothelin-1 in the kidney tissue homogenate was decreased by 18.65%, 11.27%, 22.84%, 19.44%, and 30.32% in the G5, G6, G7, G8, and G9 groups, respectively than G2. Overall, data suggested a significant improvement of endothelin-1 and nitric oxide activity in different organs. Therefore, the current outcomes could able to envisage a remarkable reduction of cardiovascular complications in the preventive treatment viz. G6, G7, G8, and G9 and might be beneficial various types of cardiovascular disorders and overall health.

The Potential Health Benefits of the Consciousness Energy Treated Novel Test Formulation on Various Functional Enzyme Biomarkers, Apr 5, 2020

The study objective was to investigate the effect of the Consciousness Energy Treated test formul... more The study objective was to investigate the effect of the Consciousness Energy Treated test formulation on vital organs like bones, heart, liver, lungs and brain using various cell-based assays. The test formulation and the cell media was divided into two parts; one untreated (UT) and other part received the Biofield Energy Treatment remotely by a renowned Biofield Energy Healer, Shirley Theresa Holmlund, Canada and was labeled as the Biofield Energy Treated (BT) test formulation/media. Cell viability data suggested that the test formulation was safe and non-toxic in six different cells. The Biofield Energy Treated Medium (BT-Med) + Biofield Treated Test Item (BT-TI) group showed 115.6% and 53.3% restoration of viable cells at 10 and 25 μg/mL, respectively in human cardiac fibroblasts cells (HCF) compared to the UTMed + UT-TI group. Moreover, the BT-Med + UT-TI group showed 113.5% and 73.5% restoration of cell viability at 0.1 and 1 μg/mL, respectively in human hepatoma cells (HepG2) compared to the untreated group. Furthermore, 101.1%, 829.8% and 698.9% restoration of cell viability was observed in adenocarcinomic human alveolar basal epithelial cells (A549) by UT-Med + BT-TI, BT-Med + UT-TI and BT-Med + BT-TI groups, respectively at 10 μg/mL compared to the untreated. The alkaline phosphatase (ALP) level was significantly increased by 97.9% and 69.7% in the UT-Med + BT-TI and BT-Med + BT-TI groups, respectively at 50 μg/mL in human bone osteosarcoma cells (MG-63) compared to the untreated. Additionally, the level of ALP was significantly increased by 58.2% in the BT-Med + BT-TI group at 1 μg/mL in human endometrial adenocarcinoma cells (Ishikawa) compared to the untreated. The percent protection of HCF (heart) cells (decreased of LDH activity) was significantly increased by 67.4% (at 0.1 μg/mL), 80.4% (at 0.1 μg/mL) and 119.8% (at 10 μg/mL) in the UT-Med + BT-TI, BT-Med + UT-TI, BT-Med + BT-TI groups, respectively compared to the untreated. The percent protection of HepG2 (liver) cells (decreased of ALT activity) was significantly increased by 57.6% and 82.5% in the BT-Med + UT-TI group at 25 and 63 μg/mL, respectively; while 123.9% at 10 μg/mL in the BT-Med + BT-TI group compared to untreated. The percent protection of A549 (lungs) cells (increased of SOD activity) was significantly increased by 53.6% and 59% in the UT-Med + BT-TI and BT-Med + BT-TI groups, respectively at 10 μg/mL compared to the untreated. Serotonin level was significantly increased by 85.3% in the UT-Med + BT-TI and BT-Med + BT-TI groups at 0.1 μg/mL as compared to untreated in human neuroblastoma cells (SH-SY5Y). The relative quantification (RQ) of vitamin D receptor (VDR) was significantly increased by 245.9% and 211.5% at 10 and 50 μg/mL, respectively in the UT-Med + BT-TI group; while 174.3% (at 10 μg/mL) in the BT-Med + UT-TI group as compared to the untreated in MG-63 cells. Overall, these results suggest that Biofield Energy Treated test formulation has significantly improved the bones, heart, liver, lungs and brain functional enzymes biomarkers. Altogether data suggest that the Biofield Energy Treatment (The Trivedi Effect®) can be useful to protect and maintain the normal function of each vital organ such as lungs, liver, heart, brain, and bones.Therefore, The Trivedi Effect® can be used as a complementary and alternative therapy against several disorders such as heart attack, coronary artery disease, heart failure, arrhythmias, congenital heart disease, cardiomyopathy, Wilson disease, hemochromatosis, cirrhosis, liver cancer, pneumonia, emphysema, chronic bronchitis, asthma, osteoporosis, cystic fibrosis, etc.

LC-MS and GC-MS Based Isotopic Abundance Ratio Analysis of The Consciousness Energy Healing Treated Ascorbic Acid, Mar 18, 2021

Ascorbic acid is required by both plants and animals for the essential metabolic process. It is s... more Ascorbic acid is required by both plants and animals for the essential metabolic process. It is sufficiently available in the citrus fruits, tomatoes, potatoes, red peppers, milk, oysters, animal liver, etc. In this study, the LC-MS and GC-MS were used to characterize the structural properties and isotopic abundance ratio to evaluate the impact of the Trivedi Effect®-Consciousness Energy Healing Treatment on L-ascorbic acid compared to the control sample. The test sample was divided into two parts, one part of ascorbic acid was considered as a control sample, while the second part only received the Trivedi Effect®-Consciousness Energy Healing Treatment remotely by a renowned Biofield Energy Healer, Dahryn Trivedi and termed as a Biofield Energy Treated sample. The LC-MS spectra of both the control and Treated samples at retention time (Rt) 1.8minutes exhibited the mass of the deprotonated molecular ion peak at m/z 175 [M-H]- (calculated for C6H7O6-, 175.02). The peak area of the treated sample (3607446.27) was significantly decreased by 65.05% compared to the control sample (10320794.8). The LC-MS based isotopic abundance ratio of PM+1/PM (2H/1H or 13C/12C or 17O/16O) in the treated ascorbic acid was significantly increased by 119.71% compared with the control sample. Thus, 13C, 2H, and 17O contributions from (C6H7O6)- to m/z 176 in the treated sample were significantly increased compared with the control sample. The gas chromatographic peak area of the treated sample (12.74) was significantly decreased by 31.1% compared to the control sample (18.49). Similarly, the GC-MS based isotopic abundance ratio of PM+2/PM in the treated ascorbic acid was significantly increased by 28.74% compared with the control sample. So, 18O contributions from (C6H8O6)+ to m/z 177 in the Biofield Energy Treated sample were significantly increased compared with the control sample. The isotopic abundance ratio of PM+1/PM (18O/16O) in the treated ascorbic acid was significantly increased compared to the control sample. The increased isotopic composition of the Trivedi Effect®-Consciousness Energy Healing Treated ascorbic acid might have altered the neutron to proton ratio in the nucleus. The changes in isotopic abundance could be due to changes in nuclei possibly through the interference of neutrino particles via the Trivedi Effect®-Consciousness Energy Healing Treatment. The increased isotopic abundance ratio and peak area of the treated ascorbic acid may increase the intra-atomic bond strength, increase its stability. This new form of ascorbic acid would be very useful to design the better pharmaceutical formulations that might offer better therapeutic response against scurvy, obesity, cardiovascular diseases, hypertension, Alzheimer’s disease, cancer, rheumatoid arthritis, etc.

Impact of Consciousness Energy Healing Treatment on the Structure and Isotopic Abundance Ratio of 6-Mercaptopurine, Feb 5, 2021

6-Mercaptopurine is an anti-cancer chemotherapy drug classified as an antimetabolite. In this stu... more 6-Mercaptopurine is an anti-cancer chemotherapy drug classified as an antimetabolite. In this study, the impact of the Trivedi Effect® (Consciousness Energy Healing Treatment) on the structural properties and the isotopic abundance ratio of 6-mercaptopurine were evaluated using LC-MS and GC-MS spectroscopy. The test sample 6-mercaptopurine was divided and termed as control and Biofield Energy Treated sample. The treated part of the sample only received the Trivedi Effect®-Consciousness Energy Healing Treatment remotely by a renowned Biofield Energy Healer, Dahryn Trivedi. The LC-MS spectra of both the samples at retention time (Rt) 2.2 minutes exhibited the mass of the protonated molecular ion peak at m/z 173 [M+H]+ (calculated for C5H5N4S+, 153.18). The peak area of the treated 6-mercaptopurine was significantly increased by 94.62% compared to the control sample. The LC-MS based isotopic abundance ratio of PM+1/PM in the treated mercaptopurine was significantly increased by 107.92% compared with the control sample. Similarly, the GC-MS based isotopic abundance ratio of PM+2/PM in the treated 6-mercaptopurine was significantly increased by 25.78% compared with the control sample. Thus,13C, 2H, 15N, 33S, and 18O contributions from (C5H5N4S)+ to m/z 154 in the treated sample were significantly increased compared with the control sample. The isotopic abundance ratio of PM+1/PM (2H/1H or 13C/12C or 15N/14N or 33S/32S) and PM+2/PM (34S/32S) in the treated 6-mercaptopurine was significantly improved compared to the control sample. The significant increase in the peak area, isotopic abundance and mass peak intensities could be due to changes in nuclei possibly happened due to the interference of neutrino particles via the Trivedi Effect®. The increased isotopic abundance ratio of the treated sample would improve the strength of the chemical bond, increase the physical and chemical stability of 6-mercaptopurine in the body. The nove l6-mercaptopurine would be better designing more efficacious pharmaceutical formulations that might offer better more bioavailability and therapeutic response against acute lymphocytic leukemia, chronic myeloid leukemia, Crohn’s disease, and ulcerative colitis, etc.

Characterization of the Consciousness Energy Healing Treated Cholecalciferol Using LC-MS and GC-MS Spectrometry, Apr 15, 2021

Vitamin D3 (cholecalciferol) is a fat-soluble vitamin, which widely used for the prevention and t... more Vitamin D3 (cholecalciferol) is a fat-soluble vitamin, which widely used for the prevention and treatment rickets, osteoporosis, arthritis, Parkinson’s and Alzheimer’s diseases, autoimmune disease, dementia, glucose intolerance, etc. The impact of the Trivedi Effect®-Consciousness Energy Healing Treatment on the structural properties and the isotopic abundance ratio of cholecalciferol were evaluated using LC-MS and GC-MS spectroscopy. The test sample cholecalciferol was divided into control and treated parts. Only, the treated cholecalciferol was received the Trivedi Effect®-Consciousness Energy Healing Treatment remotely by a renowned Biofield Energy Healer, Dahryn Trivedi. The LC-MS spectra of both the samples at retention time (Rt) ~22 minutes exhibited the mass of the molecular ion peak at m/z 385.25 (calcd for C27H45O+, 385.35). The LC-MS based isotopic abundance ratio of PM+1/PM in the treated cholecalciferol was increased by 0.74% compared with the control sample. But, the GC-MS based isotopic abundance ratio of PM+1/PM and PM+2/PM in the treated cholecalciferol was significantly increased by 66.39% and 62.69%, respectively compared with the control sample. Hence,13C, 2H, 17O, and 18O contributions from C27H44O+ to m/z 386 and 387 in the treated cholecalciferol were significantly increased compared with the control sample. The isotopic abundance ratios of PM+1/PM (2H/1H or 13C/12C or 17O/16O) and PM+2/PM (18O/16O) in the treated cholecalciferol were significantly increased as compared to the control sample. The increased isotopic composition of the Trivedi Effect®-Consciousness Energy Healing Treated cholecalciferol might have altered the neutron to proton ratio in the nucleus via the possible mediation of neutrino. The increased isotopic abundance ratio of the treated cholecalciferol may increase the intra-atomic bond strength, increase its stability. The new form of cholecalciferol would be better designing novel pharmaceutical formulations that might be more stable and more efficacious for the prevention and treatment of various diseases such as vitamin D deficiency, rickets, osteoporosis, arthritis, multiple sclerosis, cancer, diabetes mellitus, mental disorders, cardiovascular diseases, hypertension, infections, influenza, cognitive impairment in older adults, Parkinson’s and Alzheimer’s diseases, autoimmune disease, dementia, glucose intolerance, multiple sclerosis, etc.

Evaluation of the Isotopic Abundance Ratio of Consciousness Energy Healing Treated L-Tryptophan Using LC-MS Spectrometry, Apr 15, 2021

L-tryptophan is an essential α-amino acid, necessary for the normal growth in newborns, nitrogen ... more L-tryptophan is an essential α-amino acid, necessary for the normal growth in newborns, nitrogen balance in adults, protein synthesis, precursor of serotonin, melatonin, niacin, and albeit inefficiently in human, also the precursor of indole alkaloids and auxins in plants. This current study was designed to investigate the impact of the Trivedi Effect®-Biofield Energy Healing Treatment (Blessing) on the structural properties and the isotopic abundance ratio of L-tryptophan using LC-MS analytical technique. L-tryptophan sample was divided into two parts, one part of L-tryptophan was considered as the control sample (no Biofield Energy Treatment was provided), while the second part was treated with the Trivedi Effect®-Consciousness Energy Healing Treatment/Blessing remotely by a renowned Biofield Energy Healer, Dahryn Trivedi and termed as the treated sample. The mass spectra of both the control and treated samples with respect to the chromatographic peak at retention time (Rt) 2.1 minutes exhibited the mass of the molecular ion peak adduct with hydrogen ion at m/z 205.08 (calcd for C11H13N2O2+, 205.1), along with low molecular fragmented mass peaks at m/z 188, 159, and 102 for C11H12N2O2+, C10H11N2+, and C8H6+, respectively were also observed. The isotopic abundance ratio of PM+1/PM (2H/1H or 13C/12C or 15N/14Nor17O/16O) in the treated L-tryptophan was significantly increased by 35.93% compared with the control sample. Hence,the 13C, 2H, 15N, and 17O contributions from C11H13N2O2+ to m/z 206.08 in the treated L-tryptophan was significantly increased compared to the control sample. It could be hypothesized that the changes in the isotopic abundance and mass peak intensities due to the modification in nuclei possibly through the interference of neutrino particles using the Trivedi Effect®-Consciousness Energy Healing Treatment. The Biofield Energy Treated/Blessed L-tryptophan with increased stable isotopic abundance ratio might have changed the physicochemical properties with higher force constant in the molecule. The new form of treated L-tryptophan would be a better and more stable in the supplements, nutraceutical, and pharmaceutical formulations, which would be advantageous for the prevention and treatment of pellagra, depression, kynurenine. It could also maintain the normal label of tryptophan and avoid increase of its metabolite, lower the neurotoxin and a metabotoxin behavior, glutaric aciduria type I (glutaric acidemia type I) disorder, eosinophilia-myalgia syndrome (EMS), incurable and sometimes fatal flu-like neurological condition, etc. As tryptophan is the precursor for the plant hormones like indole alkaloids and auxins, hence, this treated L-tryptophan would be advantageous for the improvement of yield, productivity, and quality of crops and other plants.

The LC-MS and GC-MS Based Isotopic Abundance Ratio Analysis of the Biofield Energy Treated Metronidazole, Mar 19, 2021

Metronidazole is a well-known antibacterial and antiprotozoal antibiotic. In this study, the impa... more Metronidazole is a well-known antibacterial and antiprotozoal antibiotic. In this study, the impact of the Trivedi Effect®-Consciousness Energy Healing Treatment on the structural properties and the isotopic abundance ratio of metronidazole were evaluated using LC-MS and GC-MS spectroscopy. The test sample (metronidazole) was divided into two control and treated parts. Only the treated sample received the Trivedi Effect®-Consciousness Energy Healing Treatment remotely by a renowned Biofield Energy Healer, Dahryn Trivedi. The LC-MS spectra of both the samples of metronidazole at the retention time 2.61 minutes exhibited the mass of the protonated molecular ion peak at m/z 172 [M+H]+, but the peak area of the treated metronidazole was significantly decreased by 13.1% compared to the control sample. The LC-MS and GC-MS based isotopic abundance ratios of PM+1/PM in the treated metronidazole was significantly increased by 46.43% and 13.52%, respectively compared with the control sample. Thus, 13C, 2H, 15N, and 17O contributions from (C6H10N3O3)+ to m/z 173 in the treated sample were significantly increased compared with the control sample. The increased isotopic composition in the molecular level of the treated metronidazole might be due to the alteration in neutron to proton ratio in the nucleus possibly through the interference of neutrino via the Trivedi Effect®. The isotopic abundance ratios 2H/1H, 13C/12C, 17O/16O, and 15N/14N would highly influence the atomic bond vibration of treated metronidazole. The increased isotopic abundance ratio of the treated metronidazole would stronger the chemical bond and increase the stability in the body. The treated metronidazole would be very useful to design more efficacious pharmaceutical formulations that might offer better therapeutic response againstbacterial vaginosis, giardiasis, trichomoniasis, pseudomembranous colitis, pelvic inflammatory disease;liver, skin, brain, and respiratory tract infections; aspiration pneumonia, rosacea, intra-abdominal infections, lung abscess, fungating wounds, periodontitis, amoebiasis, oral infections, etc.

LC-MS and GC-MS Spectrometry Based Isotopic Abundance Ratio Analysis of the Consciousness Energy Healing Treated Pyridoxine Using LC-MS and GC-MS Spectrometry, Mar 5, 2021

Pyridoxine (vitamin B6) is commonly found in foods and dietary supplements, has an important role... more Pyridoxine (vitamin B6) is commonly found in foods and dietary supplements, has an important role in physiologic development. In this study, the influence of the Trivedi Effect®-Biofield Energy Healing Treatment on the structural properties and the isotopic abundance ratio of vitamin B6 were evaluated using LC-MS and GC-MS. Vitamin B6 sample was divided into two parts and termed as control and treated samples. Only the treated vitamin B6 was received the Trivedi Effect®-Consciousness Energy Healing Treatment remotely by a well-known Biofield Energy Healer, Dahryn Trivedi. The LC-MS spectra of both the vitamin B6 samples at retention time 2.3 min exhibited the mass of the protonated molecular ion peak [M+H]+ at m/z 170 (calculated for C8H12NO3+, 170.08) in the MS spectrum. The peak area% of the treated vitamin B6 was increased by 1.32% compared to the control sample. The isotopic abundance ratio of PM+1/PM in the treated vitamin B6 was significantly decreased by 36.94% compared with the control sample. Thus, 13C, 2H, 15N, and 17O contributions from (C8H12NO3)+ to m/z 171 in the treated sample were significantly decreased compared with the control sample. Similarly, in the GC-MS chromatograms, the peak area of the treated sample was increased by 4.54% compared to the control sample. Similarly, the mass peak intensity of the treated vitamin B6 at m/z 153 was significantly increased by 66.69% compared to the control sample. The isotopic abundance ratio of PM+1/PM (2H/1H or 13C/12C or 15N/14N or 17O/16O) and peak area in the treated vitamin B6 was significantly decreased compared to the control sample. The decreased isotopic abundance ratio of the treated vitamin B6 may decrease the intra-atomic bond strength, decrease its physical stability. The increased peak area of the treated vitamin B6 might be responsible for the increase in solubility and bioavailability compared to the control sample. The new form of vitamin B6 would be better for designing more efficacious pharmaceutical formulations for the prevention and treatment of vitamin B6 deficiency, anaemia, seizures, cardiovascular disease, tuberculosis, Alzheimer’s disease, cancer, anxiety, hypertension, asthma, depression, dysmenorrhea, breast pain, etc.

The Isotopic Abundance Ratio Analysis of the Consciousness Energy Healing Treated Berberine Chloride Using LC-MS and GCMS Analytical Techniques, Mar 10, 2021

Berberine is a benzylisoquinoline alkaloid which has enormous therapeutic potential, but the bioa... more Berberine is a benzylisoquinoline alkaloid which has enormous therapeutic potential, but the bioavailability is very poor due to its low solubility and poor intestinal absorption. In this study, the impact of the Trivedi Effect®-Biofield Energy Healing Treatment on the structural properties and the isotopic abundance ratio of berberine chloride was evaluated using advanced spectroscopic methods. Berberine chloride sample was divided into control and treated parts. Only the treated part was received the Trivedi Effect®-Consciousness Energy Healing Treatment remotely by a famous Biofield Energy Healer, Dahryn Trivedi. The LC-MS spectra of both the berberine chloride samples observed at retention time 2 minutes and the molecular ion peak at m/z 336.25 [M]+ (calculated for C20H18NO4+, 336.12). The LC-MS based isotopic abundance ratio of PM+1/PM in the treated berberine chloride was significantly decreased by 18.53% compared with the control sample. Similarly, the GC-MS based isotopic abundance ratio of PM+1/PM in the treated berberine chloride was decreased by 4.69% compared with the control sample. Thus, 13C, 2H, 15N, and 17O contributions from (C20H18NO4)+ to m/z 337 in the treated sample were significantly decreased compared with the control sample. But, the isotopic abundance ratio of PM+2/PM in the treated sample was significantly increased by 11.52% compared with the control sample. Hence, 18O contribution from (C20H16NO4)3+ to m/z 336 in the treated sample was significantly increased compared with the control sample. The isotopic abundance ratios of PM+1/ PM (2H/1H or 13C/12C or 15N/14N or 17O/16O) and PM+2/PM (18O/16O) in the treated berberine chloride were significantly altered compared to the control sample. The changes in isotopic abundance might be due to changes in nuclei possibly through the interference of neutrino particles via the Trivedi Effect®-Consciousness Energy Healing Treatment. The decreased isotopic abundance ratio (PM+1/PM) of the Consciousness Energy Healing Treated berberine chloride may decrease the chemical bond strength, influence its stability, and bioavailability in the body. The new form of berberine chloride would be more efficacious novel pharmaceutical formulations that might offer better solubility, dissolution, absorption, bioavailability and therapeutic response against diarrhoea, gastroenteritis, bacterial and fungal infections, cancer, arrhythmia, diabetes, hyperlipidemia, inflammation, etc.

Impact of Consciousness Energy Healing Treatment on the Isotopic Abundance Ratio of Sulfamethoxazole Using LC-MS and GC-MS Spectrometry, Mar 8, 2021

Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic which is commonly used for the treatm... more Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic which is commonly used for the treatment of infections caused by bacteria. In this study, the impact of the Trivedi Effect®-Biofield Energy Healing Treatment on the structural properties and the isotopic abundance ratio of sulfamethoxazole was studied using LC-MS and GC-MS spectroscopy. Sulfamethoxazole sample was divided into two parts, one part of sulfamethoxazole was considered as control (no Biofield Energy Treatment was provided), while the second part was received the Consciousness Energy Healing Treatment remotely by a famous Biofield Energy Healer, Dahryn Trivedi and termed as a treated sample. The LC-MS spectra of both the samples at retention time (Rt) 2.5 minutes exhibited the mass of the deprotonated molecular ion peak at m/z 252 [M-H]-. The peak area of the treated sulfamethoxazole was significantly increased by 42.96% compared to the control sample. The LC-MS based isotopic abundance ratio of PM+1/PM in the treated sulfamethoxazole was significantly decreased by 49.56% compared with the control sample. Thus, 13C, 2H, 15N, 17O, and 33S contributions from (C10H10N3O3S)- to m/z 253 in the treated sample were significantly decreased compared with the control sample. The GC-MS peak area% of the treated sample was significantly increased by 80.3% compared to the control sample. The GC-MS based isotopic abundance ratio of PM+1/PM and PM+2/PM in the treated sulfamethoxazole was significantly altered by 119.53% and -25.48%, respectively compared with the control sample. Hence, 13C, 2H, 15N, 17O, 18O, 33S, and 34S contributions from (C10H11N3O3S)+ to m/z 254 and 255 in the treated sample were significantly altered compared with the control sample. The isotopic abundance ratios of PM+1/PM (2H/1H or 13C/12C or 15N/14N or 17O/16O or 33S/32S) and PM+2/PM (18O/16O or 34S/32S) in the treated sulfamethoxazole were significantly altered compared to the control sample. It can be assumed that the changes in peak area%, isotopic abundance, and mass peak intensities could be due to changes in nuclei possibly through the interference of neutrino particles via the Trivedi Effect®. The new form of sulfamethoxazole would be more efficacious pharmaceutical formulations that might offer better solubility, dissolution, absorption, bioavailability and therapeutic response against urinary tract infections, tuberculosis, traveler’s diarrhoea, ear infections, shigellosis, bronchitis, and pneumocystis jiroveci pneumonia, etc.

The LC-MS and GC-MS Based Isotopic Abundance Ratio Analysis of the Consciousness Energy Healing Treated Silver Sulfadiazine, Feb 22, 2021

Silver sulfadiazine is a topical antibiotic helps to prevent and treat wound infections in patien... more Silver sulfadiazine is a topical antibiotic helps to prevent and treat wound infections in patients with severe burns. This research was performed to evaluate the impact of the Trivedi Effect® - Consciousness Energy Healing Treatment on the structural properties and the isotopic abundance ratio of silver sulfadiazine using spectroscopic and chromatographic techniques. The test sample silver sulfadiazine sample was divided into control and treated parts. Only the treated part of silver sulfadiazine was received the Trivedi Effect®-Consciousness Energy Healing Treatment remotely by a renowned Biofield Energy Healer, Dahryn Trivedi. The LC-MS spectra of both the samples at retention time (Rt) 4.1 minutes exhibited the mass of the protonated molecular ion peak at m/z 251.08 (calculated for C10H11N4O2S+, 251.06) was found to be sulfadiazine. The chromatographic peak area of the treated silver sulfadiazine was significantly increased by 20.35% compared to the control sample. The result indicated that the solubility profile of the treated silver sulfadiazine must have increased significantly after the Biofield Energy Treatment compared with the control sample. The LC-MS based isotopic abundance ratio of PM+1/PM in the treated sulfadiazine was significantly increased by 31.88% compared with the control sample. Similarly, the GC-MS based isotopic abundance ratio of PM+1/PM and PM+2/PM in the treated sulfadiazine was significantly increased by 9.74% and 15.13%, respectively compared with the control sample. Hence, 13C, 2H, 15N, 17O, 33S, and 34S contributions from (C7H9N2O2S)+ to m/z 186 and 187 in the treated sulfadiazine were significantly increased compared to the control sample. Thus, the isotopic abundance ratios of PM+1/PM (2H/1H or 13C/12C or 15N/14N or 17O/16O or 33S/32S) and PM+2/PM (34S/32S) in the treated sulfadiazine were significantly increased compared to the control sample. The changes in isotopic abundance and peak area might be due to changes in nuclei possibly via the interference of neutrino particles controlled by the Trivedi Effect®-Consciousness Energy Healing Treatment. The increased isotopic abundance ratio of the treated silver sulfadiazine might improve the chemical bond strength, led to increase the stability in the body. This novel silver sulfadiazine would be more efficacious in pharmaceutical formulations which might offer better solubility, bioavailability, and therapeutic response against bacterial infections, superficial and partial thickness burn injuries, etc.

Isotopic Abundance Ratio Analysis of the Consciousness Energy Healing Treated Flutamide using LC-MS and GC-MS Spectrometry, Feb 6, 2021

Flutamide is used to treat prostate cancer, which acts by blocking the action of exogenous testos... more Flutamide is used to treat prostate cancer, which acts by blocking the action of exogenous testosterone binding through its androgen receptor. This study was designed and performed to investigate the impact of the Trivedi Effect®-Consciousness Energy Healing Treatment on the structural properties and the isotopic abundance ratio of flutamide using LC-MS and GC-MS spectroscopy. Flutamide sample was divided into control and treated parts. Only the treated flutamide received the Trivedi Effect®-Consciousness Energy Healing Treatment remotely by a famous Biofield Energy Healer, Dahryn Trivedi. The LC-MS spectra of both the samples at retention time (Rt) 3.4 minutes exhibited the mass of the deprotonated molecular ion peak at m/z 275.08 [M-H]-. The peak area of the treated sample was significantly increased by 92.42% compared to the control sample, which indicated that the solubility profile of the treated sample was significantly increased compared to the control sample. The LC-MS based isotopic abundance ratio of PM+1/PM (2H/1H or 13C/12C or 15N/14N or 17O/16O) in the treated flutamide was significantly increased by 59.48% compared with the control sample. The GC-MS based isotopic abundance ratio of PM+1/PM in the treated flutamide sample was increased by 10.39% compared with the control sample. The results indicated that the 13C, 2H, 15N, and 17O contributions from (C11H11F3N2O3)+ to m/z 277 in the treated sample were significantly increased compared with the control sample. The isotopic abundance ratio of PM+1/PM (2H/1H or 13C/12C or 15N/14N or 17O/16O) in the treated flutamide was significantly increased compared to the control sample. The changes in the peak area and isotopic abundance could be due to changes in nuclei possibly through the interference of neutrino via the Trivedi Effect®-Consciousness Energy Healing Treatment. The new form of treated flutamide was formed that might have increase the chemical bond strength, stability, solubility, bioavailability, and efficacy, which could be very much useful to design more efficacious pharmaceutical formulations against prostate cancer, androgen-dependent skin and hair conditions including acne, seborrhea, hirsutism, and scalp hair loss, hyperandrogenism, as well useful for feminizing hormone therapy aimed at transgender women.