Alice Wong - Profile on Academia.edu (original) (raw)

Papers by Alice Wong

Research paper thumbnail of Constitutive and conditional cadherin expression in cultured human ovarian surface epithelium: Influence of family history of ovarian cancer

International Journal of Cancer, 1999

Epithelial ovarian carcinomas arise in a simple mesothelium (ovarian surface epithelium, OSE) but... more Epithelial ovarian carcinomas arise in a simple mesothelium (ovarian surface epithelium, OSE) but exhibit properties of oviductal and endometrial epithelia. Thus, during malignant progression, their differentiation proceeds from simple to complex, in contrast to carcinomas in other tissues. Related changes in OSE of women with a history of familial ovarian cancer indicate that this aberrant differentiation is initiated very early in neoplastic progression. The mechanisms underlying this process are not understood.

Research paper thumbnail of Ovarian Surface Epithelium: Biology, Endocrinology, and Pathology

Endocrine Reviews, 2001

The epithelial ovarian carcinomas, which make up more than 85% of human ovarian cancer, arise in ... more The epithelial ovarian carcinomas, which make up more than 85% of human ovarian cancer, arise in the ovarian surface epithelium (OSE). The etiology and early events in the progression of these carcinomas are among the least understood of all major human malignancies because there are no appropriate animal models, and because methods to culture OSE have become available only recently. The objective of this article is to review the cellular and molecular mechanisms that underlie the control of normal and neoplastic OSE cell growth, differentiation, and expression of indicators of neoplastic progression. We begin with a brief discussion of the development of OSE, from embryonic to the adult. The pathological and genetic changes of OSE during neoplastic progression are next summarized. The histological characteristics of OSE cells in culture are also described. Finally, the potential involvement of hormones, growth factors, and cytokines is discussed in terms of their contribution to our understanding of the physiology of normal OSE and ovarian cancer development. (Endocrine Reviews 22: 2001)

Research paper thumbnail of Constitutive and conditional cadherin expression in cultured human ovarian surface epithelium: Influence of family history of ovarian cancer

International Journal of Cancer, 1999

Epithelial ovarian carcinomas arise in a simple mesothelium (ovarian surface epithelium, OSE) but... more Epithelial ovarian carcinomas arise in a simple mesothelium (ovarian surface epithelium, OSE) but exhibit properties of oviductal and endometrial epithelia. Thus, during malignant progression, their differentiation proceeds from simple to complex, in contrast to carcinomas in other tissues. Related changes in OSE of women with a history of familial ovarian cancer indicate that this aberrant differentiation is initiated very early in neoplastic progression. The mechanisms underlying this process are not understood.

Research paper thumbnail of Ovarian Surface Epithelium: Biology, Endocrinology, and Pathology

Endocrine Reviews, 2001

The epithelial ovarian carcinomas, which make up more than 85% of human ovarian cancer, arise in ... more The epithelial ovarian carcinomas, which make up more than 85% of human ovarian cancer, arise in the ovarian surface epithelium (OSE). The etiology and early events in the progression of these carcinomas are among the least understood of all major human malignancies because there are no appropriate animal models, and because methods to culture OSE have become available only recently. The objective of this article is to review the cellular and molecular mechanisms that underlie the control of normal and neoplastic OSE cell growth, differentiation, and expression of indicators of neoplastic progression. We begin with a brief discussion of the development of OSE, from embryonic to the adult. The pathological and genetic changes of OSE during neoplastic progression are next summarized. The histological characteristics of OSE cells in culture are also described. Finally, the potential involvement of hormones, growth factors, and cytokines is discussed in terms of their contribution to our understanding of the physiology of normal OSE and ovarian cancer development. (Endocrine Reviews 22: 2001)

Research paper thumbnail of CLINICAL TRIAL OF A LOW-TEMPERATURE PLASTIC ANTERIOR ANKLE FOOT ORTHOSIS

CLINICAL TRIAL OF A LOW-TEMPERATURE PLASTIC ANTERIOR ANKLE FOOT ORTHOSIS

American Journal of Physical Medicine & Rehabilitation, 1992

The modification of a new design in orthosis usually has its clinical indication. In this study, ... more The modification of a new design in orthosis usually has its clinical indication. In this study, a low-temperature thermoplastic ankle foot orthosis (AFO) was designed in anterior leaf type, called anterior AFO, to meet the need of indoor barefoot walking in Taiwan. It could be easily molded and remolded to fit the foot, as well as to adjust the position of the foot and ankle. Sixty-eight patients with acute hemiplegia were fitted with this anterior AFO during ambulation training: 46 had good fitting (67.6%), 15 had fair fitting (22.1%) and 7 had poor fitting (10.3%). Two patients were observed to have ankle clonus, and four patients experienced breakage or tear of the AFO within 4 wk. The gait characteristics were measured in six chronic hemiplegia patients to compare the effect of anterior AFO with posterior AFO (Teufel style). Their gait pattern did improve by AFO fitting, especially from the foot pressure distribution, but no significant difference between the two types of AFO was found.

Research paper thumbnail of Effect of Kinesio taping on muscle strength in athletes—A pilot study

Journal of Science and Medicine in Sport, 2008

Muscle strength is a key component of an athlete's performance and may be influenced by taping. T... more Muscle strength is a key component of an athlete's performance and may be influenced by taping. This study examined the possible immediate and delayed effects of Kinesio taping on muscle strength in quadriceps and hamstring when taping is applied to the anterior thigh of healthy young athletes. Fourteen healthy young athletes (seven males and seven females) free of knee problems were enrolled in this study. Muscle strength of the subject was assessed by the isokinetic dynamometer under three conditions: (1) without taping; (2) immediately after taping; (3) 12 h after taping with the tape remaining in situ. The result revealed no significant difference in muscle power among the three conditions. Kinesio taping on the anterior thigh neither decreased nor increased muscle strength in healthy non-injured young athletes.

Research paper thumbnail of Coordination exercise and postural stability in elderly people: Effect of Tai Chi Chuan

Archives of Physical Medicine and Rehabilitation, 2001

Wong AM, Lin Y-C, Chou S-W, Tang F-T, Wong P-Y. Coordination exercise and postural stability in e... more Wong AM, Lin Y-C, Chou S-W, Tang F-T, Wong P-Y. Coordination exercise and postural stability in elderly people: effect of Tai Chi Chuan. Arch Phys Med Rehabil 2001;82:608-12. Objective: To evaluate the effects of coordination exercise on postural stability in older individuals by Chinese shadow boxing, Tai Chi Chuan (TCC).

Research paper thumbnail of Symmetrical body-weight distribution training in stroke patients and its effect on fall prevention

Archives of Physical Medicine and Rehabilitation, 2001

Research paper thumbnail of Coordination Exercise and Postural Stability in Elderly People: Effect of Tai Chi Chuan

Wong AM, Lin Y-C, Chou S-W, Tang F-T, Wong P-Y. Coordination exercise and postural stability in e... more Wong AM, Lin Y-C, Chou S-W, Tang F-T, Wong P-Y. Coordination exercise and postural stability in elderly people: effect of Tai Chi Chuan. Arch Phys Med Rehabil 2001;82:608-12. Objective: To evaluate the effects of coordination exercise on postural stability in older individuals by Chinese shadow boxing, Tai Chi Chuan (TCC).

Research paper thumbnail of The Development and Clinical Evaluation of a Standing Biofeedback Trainer

A new standing biofeedback training device, which includes a height-adjustable work table, weight... more A new standing biofeedback training device, which includes a height-adjustable work table, weight-bearing sensors, and a real-time visual and auditory feedback system, has been developed for postural training . Sixty persons with hemiplegia after acute stroke or traumatic brain injury were randomly divided into Group A (experimental) and Group B (control) . After a training period of 4 weeks, the percentage of postural asymmetry in Group A and Group B was reduced from 17.2±10.8% and 17.0±10 .0% to 3.5±2 .2% and 10.1±6 .4 percent, respectively (p=0 .003) . There was no significant difference between subjects with right or left hemiplegia . The results indicated that this device had a positive training effect on stance symmetry in hemiplegic subjects.

Research paper thumbnail of Constitutive and conditional cadherin expression in cultured human ovarian surface epithelium: Influence of family history of ovarian cancer

International Journal of Cancer, 1999

Epithelial ovarian carcinomas arise in a simple mesothelium (ovarian surface epithelium, OSE) but... more Epithelial ovarian carcinomas arise in a simple mesothelium (ovarian surface epithelium, OSE) but exhibit properties of oviductal and endometrial epithelia. Thus, during malignant progression, their differentiation proceeds from simple to complex, in contrast to carcinomas in other tissues. Related changes in OSE of women with a history of familial ovarian cancer indicate that this aberrant differentiation is initiated very early in neoplastic progression. The mechanisms underlying this process are not understood.

Research paper thumbnail of Ovarian Surface Epithelium: Biology, Endocrinology, and Pathology

Endocrine Reviews, 2001

The epithelial ovarian carcinomas, which make up more than 85% of human ovarian cancer, arise in ... more The epithelial ovarian carcinomas, which make up more than 85% of human ovarian cancer, arise in the ovarian surface epithelium (OSE). The etiology and early events in the progression of these carcinomas are among the least understood of all major human malignancies because there are no appropriate animal models, and because methods to culture OSE have become available only recently. The objective of this article is to review the cellular and molecular mechanisms that underlie the control of normal and neoplastic OSE cell growth, differentiation, and expression of indicators of neoplastic progression. We begin with a brief discussion of the development of OSE, from embryonic to the adult. The pathological and genetic changes of OSE during neoplastic progression are next summarized. The histological characteristics of OSE cells in culture are also described. Finally, the potential involvement of hormones, growth factors, and cytokines is discussed in terms of their contribution to our understanding of the physiology of normal OSE and ovarian cancer development. (Endocrine Reviews 22: 2001)

Research paper thumbnail of Constitutive and conditional cadherin expression in cultured human ovarian surface epithelium: Influence of family history of ovarian cancer

International Journal of Cancer, 1999

Epithelial ovarian carcinomas arise in a simple mesothelium (ovarian surface epithelium, OSE) but... more Epithelial ovarian carcinomas arise in a simple mesothelium (ovarian surface epithelium, OSE) but exhibit properties of oviductal and endometrial epithelia. Thus, during malignant progression, their differentiation proceeds from simple to complex, in contrast to carcinomas in other tissues. Related changes in OSE of women with a history of familial ovarian cancer indicate that this aberrant differentiation is initiated very early in neoplastic progression. The mechanisms underlying this process are not understood.

Research paper thumbnail of Ovarian Surface Epithelium: Biology, Endocrinology, and Pathology

Endocrine Reviews, 2001

The epithelial ovarian carcinomas, which make up more than 85% of human ovarian cancer, arise in ... more The epithelial ovarian carcinomas, which make up more than 85% of human ovarian cancer, arise in the ovarian surface epithelium (OSE). The etiology and early events in the progression of these carcinomas are among the least understood of all major human malignancies because there are no appropriate animal models, and because methods to culture OSE have become available only recently. The objective of this article is to review the cellular and molecular mechanisms that underlie the control of normal and neoplastic OSE cell growth, differentiation, and expression of indicators of neoplastic progression. We begin with a brief discussion of the development of OSE, from embryonic to the adult. The pathological and genetic changes of OSE during neoplastic progression are next summarized. The histological characteristics of OSE cells in culture are also described. Finally, the potential involvement of hormones, growth factors, and cytokines is discussed in terms of their contribution to our understanding of the physiology of normal OSE and ovarian cancer development. (Endocrine Reviews 22: 2001)

Research paper thumbnail of CLINICAL TRIAL OF A LOW-TEMPERATURE PLASTIC ANTERIOR ANKLE FOOT ORTHOSIS

CLINICAL TRIAL OF A LOW-TEMPERATURE PLASTIC ANTERIOR ANKLE FOOT ORTHOSIS

American Journal of Physical Medicine & Rehabilitation, 1992

The modification of a new design in orthosis usually has its clinical indication. In this study, ... more The modification of a new design in orthosis usually has its clinical indication. In this study, a low-temperature thermoplastic ankle foot orthosis (AFO) was designed in anterior leaf type, called anterior AFO, to meet the need of indoor barefoot walking in Taiwan. It could be easily molded and remolded to fit the foot, as well as to adjust the position of the foot and ankle. Sixty-eight patients with acute hemiplegia were fitted with this anterior AFO during ambulation training: 46 had good fitting (67.6%), 15 had fair fitting (22.1%) and 7 had poor fitting (10.3%). Two patients were observed to have ankle clonus, and four patients experienced breakage or tear of the AFO within 4 wk. The gait characteristics were measured in six chronic hemiplegia patients to compare the effect of anterior AFO with posterior AFO (Teufel style). Their gait pattern did improve by AFO fitting, especially from the foot pressure distribution, but no significant difference between the two types of AFO was found.

Research paper thumbnail of Effect of Kinesio taping on muscle strength in athletes—A pilot study

Journal of Science and Medicine in Sport, 2008

Muscle strength is a key component of an athlete's performance and may be influenced by taping. T... more Muscle strength is a key component of an athlete's performance and may be influenced by taping. This study examined the possible immediate and delayed effects of Kinesio taping on muscle strength in quadriceps and hamstring when taping is applied to the anterior thigh of healthy young athletes. Fourteen healthy young athletes (seven males and seven females) free of knee problems were enrolled in this study. Muscle strength of the subject was assessed by the isokinetic dynamometer under three conditions: (1) without taping; (2) immediately after taping; (3) 12 h after taping with the tape remaining in situ. The result revealed no significant difference in muscle power among the three conditions. Kinesio taping on the anterior thigh neither decreased nor increased muscle strength in healthy non-injured young athletes.

Research paper thumbnail of Coordination exercise and postural stability in elderly people: Effect of Tai Chi Chuan

Archives of Physical Medicine and Rehabilitation, 2001

Wong AM, Lin Y-C, Chou S-W, Tang F-T, Wong P-Y. Coordination exercise and postural stability in e... more Wong AM, Lin Y-C, Chou S-W, Tang F-T, Wong P-Y. Coordination exercise and postural stability in elderly people: effect of Tai Chi Chuan. Arch Phys Med Rehabil 2001;82:608-12. Objective: To evaluate the effects of coordination exercise on postural stability in older individuals by Chinese shadow boxing, Tai Chi Chuan (TCC).

Research paper thumbnail of Symmetrical body-weight distribution training in stroke patients and its effect on fall prevention

Archives of Physical Medicine and Rehabilitation, 2001

Research paper thumbnail of Coordination Exercise and Postural Stability in Elderly People: Effect of Tai Chi Chuan

Wong AM, Lin Y-C, Chou S-W, Tang F-T, Wong P-Y. Coordination exercise and postural stability in e... more Wong AM, Lin Y-C, Chou S-W, Tang F-T, Wong P-Y. Coordination exercise and postural stability in elderly people: effect of Tai Chi Chuan. Arch Phys Med Rehabil 2001;82:608-12. Objective: To evaluate the effects of coordination exercise on postural stability in older individuals by Chinese shadow boxing, Tai Chi Chuan (TCC).

Research paper thumbnail of The Development and Clinical Evaluation of a Standing Biofeedback Trainer

A new standing biofeedback training device, which includes a height-adjustable work table, weight... more A new standing biofeedback training device, which includes a height-adjustable work table, weight-bearing sensors, and a real-time visual and auditory feedback system, has been developed for postural training . Sixty persons with hemiplegia after acute stroke or traumatic brain injury were randomly divided into Group A (experimental) and Group B (control) . After a training period of 4 weeks, the percentage of postural asymmetry in Group A and Group B was reduced from 17.2±10.8% and 17.0±10 .0% to 3.5±2 .2% and 10.1±6 .4 percent, respectively (p=0 .003) . There was no significant difference between subjects with right or left hemiplegia . The results indicated that this device had a positive training effect on stance symmetry in hemiplegic subjects.