Alicia Perez - Academia.edu (original) (raw)
Papers by Alicia Perez
Revista De La Facultad De Derecho De La Universidad Complutense, 1989
Page 1. A comparison of linguistically and statistically enhanced models for speech-to-speech mac... more Page 1. A comparison of linguistically and statistically enhanced models for speech-to-speech machine translation Alicia Pérez(1), Vıctor Guijarrubia(1), Raquel Justo(1), M. Inés Torres(1), Francisco Casacuberta(2) (1)Dep. Electricity and Electronics. ...
Revista Espanola De Salud Publica, Jun 24, 2008
Ayuda. Buscador. Ver el registro completo y el enlace al documento. Registro completo. Recurso de... more Ayuda. Buscador. Ver el registro completo y el enlace al documento. Registro completo. Recurso de origen, RECyT (Repositorio Español de Ciencia y Tecnología). Identificador, http://recyt.fecyt.es/index.php/RESP/article/view/1454. ...
Medicina, Feb 1, 2008
In Río Negro Province, Argentina, human cases of hantavirus pulmonary syndrome (HPS) appeared in ... more In Río Negro Province, Argentina, human cases of hantavirus pulmonary syndrome (HPS) appeared in the region of subantartic forests. The Andes virus (ANDV) has been identified in the region both in Oligoryzomys longicaudatus rodents and in humans, with the main transmission being from rodents to humans but also showing the possibility of human to human transmission. Between 1996 and 2004, in 40 campaigns, 29.960 night-traps for capturing live rodents were set up. Blood samples were obtained from the rodents and processed using enzyme immunoassay with recombinant antigens made from ANDV. A total of 1767 rodents were captured, with a capture success of 5.9% and an antibody prevalence of 2.1%. Important differences were observed among the species captured from Andes and Steppe regions. Seropositive Oligoryzomys longicaudatus, Abrotrix olivaceus, Abrotrix xanhtothinus and Loxodontomus microtus were captured. During the 1993-2004 period, 40 HPS cases were registered.
FEBS letters, Jan 19, 2015
The structural basis of the pH dependency of the dimer-tetramer transition exhibited by Brinda... more The structural basis of the pH dependency of the dimer-tetramer transition exhibited by Brinda's type II Diocleinae lectins was investigated by equilibrium sedimentation and X-ray crystal structure determination of recombinant wild-type and site-directed single and double mutants of the pH-stable tetrameric Dioclea grandiflora lectin (r-αDGL). Releasing the peripheral site interdimeric contact between R60 and D78 rendered a mutant displaying dimer-tetramer equilibrium in the pH range equivalent to pKa±1 of the γ-COOH. Mutation of both histidines 51 and 131, but not the mutation of each His separately, abolished the formation of the Diocleinae canonical tetramer in the pH range 2.5-8.5. The X-ray structure of the double mutant r-αDGL H51G/H131N suggests that H131 plays a crucial role in networking loop 114-125 residues from all four subunits at the central cavity of the tetrameric lectin, and that H51 maintains the central cavity loops in a proper spatial orientation to make H131...
Human Language Technologies 2007: The Conference of the North American Chapter of the Association for Computational Linguistics; Companion Volume, Short Papers on XX - NAACL '07, 2007
The aim of this work is to show the ability of finite-state transducers to simultaneously transla... more The aim of this work is to show the ability of finite-state transducers to simultaneously translate speech into multiple languages. Our proposal deals with an extension of stochastic finite-state transducers that can produce more than one output at the same time. These kind of devices offer great versatility for the integration with other finite-state devices such as acoustic models in order to produce a speech translation system. This proposal has been evaluated in a practical situation, and its results have been compared with those obtained using a standard monotarget speech transducer.
Boletín chileno de parasitología, 2000
Así, el objetivo del presente trabajo es analizar los costos para los servicios de salud de la Pr... more Así, el objetivo del presente trabajo es analizar los costos para los servicios de salud de la Provincia de Río Negro, Argentina, la atención médica de los casos económicamente alternativas futuras en las estrategias de control. Para ello se obtuvo información de casos humanos ...
Medicina, 2006
The surveillance of infection for Echinococcus granulosus in the Province of Rio Negro during 198... more The surveillance of infection for Echinococcus granulosus in the Province of Rio Negro during 1980-2002 included serological and ultrasonographic screening in humans and arecoline test in dogs. In lieu of the limitations of the arecoline test the proposal was to supplant that test for the copro ELISA-copro/Western Blot complex applied to feces collected from the environment. The objective was to compare the pros and cons of the two tests and to evaluate the human and the canine infection prevalence. The working area encompassed 7 Departments with systematic canine parasiticide activities (Program Area) and 4 Departments, not endemic, as Control Area. The arecoline test was applied to the dogs in assembled groups with the voluntary participation of their owners (not randomized sampling). Samples for the detection of coproantigens were obtained from sheep farms selected at random and analyzed by the complex copro-ELISA /Western Blot. Prevalence in man was determined by screening the s...
Lecture Notes in Computer Science, 2006
Page 1. Towards the Improvement of Statistical Translation Models Using Linguistic Features* Alic... more Page 1. Towards the Improvement of Statistical Translation Models Using Linguistic Features* Alicia Pérez1, Inés Torres1, and Francisco Casacuberta2 1 Departamento de Electricidad y Electrónica. Facultad de Ciencia y Tecnologıa. ...
Proceedings of the Second Workshop on Statistical Machine Translation - StatMT '07, 2007
In order to simultaneously translate speech into multiple languages an extension of stochastic fi... more In order to simultaneously translate speech into multiple languages an extension of stochastic finite-state transducers is proposed. In this approach the speech translation model consists of a single network where acoustic models (in the input) and the multilingual model (in the output) are embedded.
Lecture Notes in Computer Science, 2011
Finding the most likely sequence of symbols given a sequence of observations is a classical patte... more Finding the most likely sequence of symbols given a sequence of observations is a classical pattern recognition problem. This problem is frequently approached by means of the Viterbi algorithm, which aims at finding the most likely sequence of states within a trellis given a ...
Revista Argentina de Microbiología, 2014
Cystic echinococcosis (CE) is an endemic disease in the province of Río Negro, Argentina. The con... more Cystic echinococcosis (CE) is an endemic disease in the province of Río Negro, Argentina. The control program against CE has developed monitoring surveillance systems. Currently, the coproELISA/Western blot (WB) test is used to determine transmission in livestock farms (epidemiological units or EU) from collected dry field-dispersed dog feces. The objective was to evaluate the prevalence of CE on livestock farms and its relationship with CE cases in children aged 0-14 years. Canine fecal samples were obtained from randomly selected livestock farms and processed by the coproELISA/WB test. Furthermore, new cases in children in the same age group mentioned above were identified. In 278 EU, 571 samples of canine feces were obtained. There were 37 positive samples for coproELISA/WB (6.5%) and the presence of transmission was demonstrated in 37 EU (13.3%). There were no significant differences (p=0.9) with the survey conducted in the period 2003-2004 while there were significant differences (p=0.02) with the EU survey of native populations conducted in 2009-2010. With respect to animal density in the work area, the EU yielding negative results had an average of 2 dogs (SD 2.1) per EU while in the EU having positive results the average was 3 dogs (SD 4.2), showing statistically significant differences (p=0.02). In children under 15 years of age, 12 cases were diagnosed. This study has identified, on average, that the cases of hydatid disease are closer in the positive fields than in the negative fields (p=0.00307).The coproELISA/WB test allowed to identify the dispersion of CE on livestock farms and its relationship with the occurrence of cases in children in 2009-2010.
Revista do Instituto de Medicina Tropical de São Paulo, 1997
Early in 1995 the first case of Hantavirus Pulmonary Syndrome was serologically confirmed in El B... more Early in 1995 the first case of Hantavirus Pulmonary Syndrome was serologically confirmed in El Bolsón (Province of Río Negro, Argentina), corresponding to the third outbreak reported in Argentina. A total of 26 cases of HPS related to the Andean region of Rio Negro Province, were reported from 1993 to 1996, 17 in El Bolsón, 4 in San Carlos de Bariloche, and 5 in Buenos Aires. The incidence rate was 5.03 x 100,000 with a mortality rate of 51.85 x 100. The occurrence of cases was mainly seasonal, with a significantly greater number in the spring, and the persons affected mainly lived in urban or periurban areas. In four cases, the affected individuals were members of a couple, spouses or live-in contacts. Seven cases were Health workers (physicians, nurses or administrative staff). Twelve cases were related among them, due to an outbreak of 80 days. Two of them did not visit the Andean region. A total of 139 rodents were captured and seven of them, Olygoryzomys longicaudatus, were found to be serologically positive. The possibility of infection by contact with rodents or fecal matter is being analyzed and also hypothesis related with interhuman transmission.
2010 Workshops on Database and Expert Systems Applications, 2010
The goal of this paper is to describe a multimodal dialogue system based project developed under ... more The goal of this paper is to describe a multimodal dialogue system based project developed under EDECÁN architecture for Softec-Ibermática company. The demonstration takes 10 min. aprox.
Veterinary Parasitology, 2005
In 2000 Guarnera et al. proposed using ELISA in canine faeces collected from the ground to detect... more In 2000 Guarnera et al. proposed using ELISA in canine faeces collected from the ground to detect dogs infected with Echinococcus granulosus, thus determining sheep farms with active transmission. The objective was to evaluate the prevalence of E. granulosus infection in sheep farms of the Patagonia. Sheep farms were randomly selected in the Provinces of Río Negro, Chubut, Neuquén, Santa Cruz and Tierra del Fuego (areas with control programs) and La Pampa (comparison area). From one to three samples of fecal matter were obtained for each sheep farm, which were processed by means of copro-ELISA test with confirmation of positive samples by copro-Western blot. A total of 1042 samples were obtained from 352 sheep farms, 26 (7.3%) proving positive. Of these 5 (6.3%) were from La Pampa, 9 (13.8%) from Neuquén, 4 (4.7%) from Río Negro, 2 (2.9%) from Chubut, 1 (5.9%) from Santa Cruz and 5 (13.9%) from Tierra del Fuego. The identification of parasitized dogs is an essential activity upon which rests the strategy of control and surveillance. Arecoline tests or coproantigen test with fecal matter obtained directly from the dog contribute information on individual prevalence, while the use of coproantigens detected in groundcollected samples transfers the dog unit of observation to units of greater epidemiological value. In the present experience, the technique employed seems promising for its application in systems of epidemiological surveillance of cystic echinococcosis and www.elsevier.com/locate/vetpar Veterinary Parasitology 128 in drawing a baseline on which to measure the progress of control programs in the Argentine Patagonia in subsequent years. #
Resumen: En un contexto de escasez de estudios sobre la utilidad informativa de las páginas Web d... more Resumen: En un contexto de escasez de estudios sobre la utilidad informativa de las páginas Web de los organismos públicos, en este trabajo se trata de analizar y valorar el contenido informativo de interés turístico de las páginas web de los grandes ayuntamientos españoles mediante el diseño de 34 variables informativas para las que se elaboran índices de información que
Revista Panamericana de Salud Pública, 2000
debe dirigirse a Edmundo Larrieu, a la siguiente dirección postal: Laprida 240 (8599) Viedma, Arg... more debe dirigirse a Edmundo Larrieu, a la siguiente dirección postal: Laprida 240 (8599) Viedma, Argentina. Correo electrónico: msrione@anmat. gov.ar ABSTRACT Asymptomatic carriers of hydatidosis: epidemiology, diagnosis, and treatment
La dirección, ante el análisis de las desviaciones para el control de gestión, debe disponer de a... more La dirección, ante el análisis de las desviaciones para el control de gestión, debe disponer de aquellos modelos matemáticos que le permitan la toma de decisiones que dicho análisis conlleva. A este respecto la decisión de investigar o no las causas de una desviación determinada tiene implicaciones económicas, lo cual supone que el modelo desarrollado para ayudar en dicha toma de decisión deba incluir los parámetros de coste beneficio del horizonte temporal correspondiente.
Neonatology, 2007
er absolute and relative values of NK cells in the very-preterm group. After that, we analyzed th... more er absolute and relative values of NK cells in the very-preterm group. After that, we analyzed the lymphocyte populations week to week (from week 31 to 41) and found the lowest values of T cells (CD4+ and CD8+) for week 36. However, lower percentages of CD4+ T cells and higher percentages of NK cells were observed in week 38 and 41. Conclusion: We found an increase in cord blood NK cells with gestational age, both in terms of absolute counts and of percentage values. Moreover, the %NK cells showed a pattern opposite to %CD4+ T cells along the studied period.
Revista De La Facultad De Derecho De La Universidad Complutense, 1989
Page 1. A comparison of linguistically and statistically enhanced models for speech-to-speech mac... more Page 1. A comparison of linguistically and statistically enhanced models for speech-to-speech machine translation Alicia Pérez(1), Vıctor Guijarrubia(1), Raquel Justo(1), M. Inés Torres(1), Francisco Casacuberta(2) (1)Dep. Electricity and Electronics. ...
Revista Espanola De Salud Publica, Jun 24, 2008
Ayuda. Buscador. Ver el registro completo y el enlace al documento. Registro completo. Recurso de... more Ayuda. Buscador. Ver el registro completo y el enlace al documento. Registro completo. Recurso de origen, RECyT (Repositorio Español de Ciencia y Tecnología). Identificador, http://recyt.fecyt.es/index.php/RESP/article/view/1454. ...
Medicina, Feb 1, 2008
In Río Negro Province, Argentina, human cases of hantavirus pulmonary syndrome (HPS) appeared in ... more In Río Negro Province, Argentina, human cases of hantavirus pulmonary syndrome (HPS) appeared in the region of subantartic forests. The Andes virus (ANDV) has been identified in the region both in Oligoryzomys longicaudatus rodents and in humans, with the main transmission being from rodents to humans but also showing the possibility of human to human transmission. Between 1996 and 2004, in 40 campaigns, 29.960 night-traps for capturing live rodents were set up. Blood samples were obtained from the rodents and processed using enzyme immunoassay with recombinant antigens made from ANDV. A total of 1767 rodents were captured, with a capture success of 5.9% and an antibody prevalence of 2.1%. Important differences were observed among the species captured from Andes and Steppe regions. Seropositive Oligoryzomys longicaudatus, Abrotrix olivaceus, Abrotrix xanhtothinus and Loxodontomus microtus were captured. During the 1993-2004 period, 40 HPS cases were registered.
FEBS letters, Jan 19, 2015
The structural basis of the pH dependency of the dimer-tetramer transition exhibited by Brinda... more The structural basis of the pH dependency of the dimer-tetramer transition exhibited by Brinda's type II Diocleinae lectins was investigated by equilibrium sedimentation and X-ray crystal structure determination of recombinant wild-type and site-directed single and double mutants of the pH-stable tetrameric Dioclea grandiflora lectin (r-αDGL). Releasing the peripheral site interdimeric contact between R60 and D78 rendered a mutant displaying dimer-tetramer equilibrium in the pH range equivalent to pKa±1 of the γ-COOH. Mutation of both histidines 51 and 131, but not the mutation of each His separately, abolished the formation of the Diocleinae canonical tetramer in the pH range 2.5-8.5. The X-ray structure of the double mutant r-αDGL H51G/H131N suggests that H131 plays a crucial role in networking loop 114-125 residues from all four subunits at the central cavity of the tetrameric lectin, and that H51 maintains the central cavity loops in a proper spatial orientation to make H131...
Human Language Technologies 2007: The Conference of the North American Chapter of the Association for Computational Linguistics; Companion Volume, Short Papers on XX - NAACL '07, 2007
The aim of this work is to show the ability of finite-state transducers to simultaneously transla... more The aim of this work is to show the ability of finite-state transducers to simultaneously translate speech into multiple languages. Our proposal deals with an extension of stochastic finite-state transducers that can produce more than one output at the same time. These kind of devices offer great versatility for the integration with other finite-state devices such as acoustic models in order to produce a speech translation system. This proposal has been evaluated in a practical situation, and its results have been compared with those obtained using a standard monotarget speech transducer.
Boletín chileno de parasitología, 2000
Así, el objetivo del presente trabajo es analizar los costos para los servicios de salud de la Pr... more Así, el objetivo del presente trabajo es analizar los costos para los servicios de salud de la Provincia de Río Negro, Argentina, la atención médica de los casos económicamente alternativas futuras en las estrategias de control. Para ello se obtuvo información de casos humanos ...
Medicina, 2006
The surveillance of infection for Echinococcus granulosus in the Province of Rio Negro during 198... more The surveillance of infection for Echinococcus granulosus in the Province of Rio Negro during 1980-2002 included serological and ultrasonographic screening in humans and arecoline test in dogs. In lieu of the limitations of the arecoline test the proposal was to supplant that test for the copro ELISA-copro/Western Blot complex applied to feces collected from the environment. The objective was to compare the pros and cons of the two tests and to evaluate the human and the canine infection prevalence. The working area encompassed 7 Departments with systematic canine parasiticide activities (Program Area) and 4 Departments, not endemic, as Control Area. The arecoline test was applied to the dogs in assembled groups with the voluntary participation of their owners (not randomized sampling). Samples for the detection of coproantigens were obtained from sheep farms selected at random and analyzed by the complex copro-ELISA /Western Blot. Prevalence in man was determined by screening the s...
Lecture Notes in Computer Science, 2006
Page 1. Towards the Improvement of Statistical Translation Models Using Linguistic Features* Alic... more Page 1. Towards the Improvement of Statistical Translation Models Using Linguistic Features* Alicia Pérez1, Inés Torres1, and Francisco Casacuberta2 1 Departamento de Electricidad y Electrónica. Facultad de Ciencia y Tecnologıa. ...
Proceedings of the Second Workshop on Statistical Machine Translation - StatMT '07, 2007
In order to simultaneously translate speech into multiple languages an extension of stochastic fi... more In order to simultaneously translate speech into multiple languages an extension of stochastic finite-state transducers is proposed. In this approach the speech translation model consists of a single network where acoustic models (in the input) and the multilingual model (in the output) are embedded.
Lecture Notes in Computer Science, 2011
Finding the most likely sequence of symbols given a sequence of observations is a classical patte... more Finding the most likely sequence of symbols given a sequence of observations is a classical pattern recognition problem. This problem is frequently approached by means of the Viterbi algorithm, which aims at finding the most likely sequence of states within a trellis given a ...
Revista Argentina de Microbiología, 2014
Cystic echinococcosis (CE) is an endemic disease in the province of Río Negro, Argentina. The con... more Cystic echinococcosis (CE) is an endemic disease in the province of Río Negro, Argentina. The control program against CE has developed monitoring surveillance systems. Currently, the coproELISA/Western blot (WB) test is used to determine transmission in livestock farms (epidemiological units or EU) from collected dry field-dispersed dog feces. The objective was to evaluate the prevalence of CE on livestock farms and its relationship with CE cases in children aged 0-14 years. Canine fecal samples were obtained from randomly selected livestock farms and processed by the coproELISA/WB test. Furthermore, new cases in children in the same age group mentioned above were identified. In 278 EU, 571 samples of canine feces were obtained. There were 37 positive samples for coproELISA/WB (6.5%) and the presence of transmission was demonstrated in 37 EU (13.3%). There were no significant differences (p=0.9) with the survey conducted in the period 2003-2004 while there were significant differences (p=0.02) with the EU survey of native populations conducted in 2009-2010. With respect to animal density in the work area, the EU yielding negative results had an average of 2 dogs (SD 2.1) per EU while in the EU having positive results the average was 3 dogs (SD 4.2), showing statistically significant differences (p=0.02). In children under 15 years of age, 12 cases were diagnosed. This study has identified, on average, that the cases of hydatid disease are closer in the positive fields than in the negative fields (p=0.00307).The coproELISA/WB test allowed to identify the dispersion of CE on livestock farms and its relationship with the occurrence of cases in children in 2009-2010.
Revista do Instituto de Medicina Tropical de São Paulo, 1997
Early in 1995 the first case of Hantavirus Pulmonary Syndrome was serologically confirmed in El B... more Early in 1995 the first case of Hantavirus Pulmonary Syndrome was serologically confirmed in El Bolsón (Province of Río Negro, Argentina), corresponding to the third outbreak reported in Argentina. A total of 26 cases of HPS related to the Andean region of Rio Negro Province, were reported from 1993 to 1996, 17 in El Bolsón, 4 in San Carlos de Bariloche, and 5 in Buenos Aires. The incidence rate was 5.03 x 100,000 with a mortality rate of 51.85 x 100. The occurrence of cases was mainly seasonal, with a significantly greater number in the spring, and the persons affected mainly lived in urban or periurban areas. In four cases, the affected individuals were members of a couple, spouses or live-in contacts. Seven cases were Health workers (physicians, nurses or administrative staff). Twelve cases were related among them, due to an outbreak of 80 days. Two of them did not visit the Andean region. A total of 139 rodents were captured and seven of them, Olygoryzomys longicaudatus, were found to be serologically positive. The possibility of infection by contact with rodents or fecal matter is being analyzed and also hypothesis related with interhuman transmission.
2010 Workshops on Database and Expert Systems Applications, 2010
The goal of this paper is to describe a multimodal dialogue system based project developed under ... more The goal of this paper is to describe a multimodal dialogue system based project developed under EDECÁN architecture for Softec-Ibermática company. The demonstration takes 10 min. aprox.
Veterinary Parasitology, 2005
In 2000 Guarnera et al. proposed using ELISA in canine faeces collected from the ground to detect... more In 2000 Guarnera et al. proposed using ELISA in canine faeces collected from the ground to detect dogs infected with Echinococcus granulosus, thus determining sheep farms with active transmission. The objective was to evaluate the prevalence of E. granulosus infection in sheep farms of the Patagonia. Sheep farms were randomly selected in the Provinces of Río Negro, Chubut, Neuquén, Santa Cruz and Tierra del Fuego (areas with control programs) and La Pampa (comparison area). From one to three samples of fecal matter were obtained for each sheep farm, which were processed by means of copro-ELISA test with confirmation of positive samples by copro-Western blot. A total of 1042 samples were obtained from 352 sheep farms, 26 (7.3%) proving positive. Of these 5 (6.3%) were from La Pampa, 9 (13.8%) from Neuquén, 4 (4.7%) from Río Negro, 2 (2.9%) from Chubut, 1 (5.9%) from Santa Cruz and 5 (13.9%) from Tierra del Fuego. The identification of parasitized dogs is an essential activity upon which rests the strategy of control and surveillance. Arecoline tests or coproantigen test with fecal matter obtained directly from the dog contribute information on individual prevalence, while the use of coproantigens detected in groundcollected samples transfers the dog unit of observation to units of greater epidemiological value. In the present experience, the technique employed seems promising for its application in systems of epidemiological surveillance of cystic echinococcosis and www.elsevier.com/locate/vetpar Veterinary Parasitology 128 in drawing a baseline on which to measure the progress of control programs in the Argentine Patagonia in subsequent years. #
Resumen: En un contexto de escasez de estudios sobre la utilidad informativa de las páginas Web d... more Resumen: En un contexto de escasez de estudios sobre la utilidad informativa de las páginas Web de los organismos públicos, en este trabajo se trata de analizar y valorar el contenido informativo de interés turístico de las páginas web de los grandes ayuntamientos españoles mediante el diseño de 34 variables informativas para las que se elaboran índices de información que
Revista Panamericana de Salud Pública, 2000
debe dirigirse a Edmundo Larrieu, a la siguiente dirección postal: Laprida 240 (8599) Viedma, Arg... more debe dirigirse a Edmundo Larrieu, a la siguiente dirección postal: Laprida 240 (8599) Viedma, Argentina. Correo electrónico: msrione@anmat. gov.ar ABSTRACT Asymptomatic carriers of hydatidosis: epidemiology, diagnosis, and treatment
La dirección, ante el análisis de las desviaciones para el control de gestión, debe disponer de a... more La dirección, ante el análisis de las desviaciones para el control de gestión, debe disponer de aquellos modelos matemáticos que le permitan la toma de decisiones que dicho análisis conlleva. A este respecto la decisión de investigar o no las causas de una desviación determinada tiene implicaciones económicas, lo cual supone que el modelo desarrollado para ayudar en dicha toma de decisión deba incluir los parámetros de coste beneficio del horizonte temporal correspondiente.
Neonatology, 2007
er absolute and relative values of NK cells in the very-preterm group. After that, we analyzed th... more er absolute and relative values of NK cells in the very-preterm group. After that, we analyzed the lymphocyte populations week to week (from week 31 to 41) and found the lowest values of T cells (CD4+ and CD8+) for week 36. However, lower percentages of CD4+ T cells and higher percentages of NK cells were observed in week 38 and 41. Conclusion: We found an increase in cord blood NK cells with gestational age, both in terms of absolute counts and of percentage values. Moreover, the %NK cells showed a pattern opposite to %CD4+ T cells along the studied period.