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Papers by Alongkote Singhato
The American Journal of Medicine, 2008
OBJECTIVE-Alcoholism is a risk factor for osteoporotic fractures and low bone density, but the ef... more OBJECTIVE-Alcoholism is a risk factor for osteoporotic fractures and low bone density, but the effects of moderate alcohol consumption on bone are unknown. We performed a systematic review and meta-analysis to assess the associations between alcohol consumption and osteoporotic fractures, bone density and bone density loss over time, bone response to estrogen replacement, and bone remodeling. METHODS-MEDLINE, Current Contents, PsychINFO, and Cochrane Libraries were searched for studies published before May 14, 2007. We assessed quality using the internal validity criteria of the US Preventive Services Task Force. RESULTS-We pooled effect sizes for 2 specific outcomes (hip fracture and bone density) and synthesized data qualitatively for 4 outcomes (non-hip fracture, bone density loss over time, bone response to estrogen replacement, and bone remodeling). Compared with abstainers, persons consuming from more than 0.5 to 1.0 drinks per day had lower hip fracture risk (relative risk = 0.80 risk [95% confidence interval, 0.71-0.91]), and persons consuming more than 2 drinks per day had higher risk (relative risk = 1.39 [95% risk confidence interval, 1.08-1.79]). A linear relationship existed between femoral neck bone density and alcohol consumption. Because studies often combined moderate and heavier drinkers in a single category, we could not assess relative associations between alcohol consumption and bone density in moderate compared with heavy drinkers. CONCLUSION-Compared with abstainers and heavier drinkers, persons who consume 0.5 to 1.0 drink per day have a lower risk of hip fracture. Although available evidence suggests a favorable effect of alcohol consumption on bone density, a precise range of beneficial alcohol consumption cannot be determined.
Journal of Food Composition and Analysis
Foods
Although fish are good sources of selenium (Se), an essential trace element for the human body, v... more Although fish are good sources of selenium (Se), an essential trace element for the human body, very limited data exist on Se content in commonly consumed fish in Thailand. Consequently, this study investigated selenium content and the effect of cooking among 10 fish species (5 freshwater and 5 marine) most-commonly consumed by the Thai people. The fish were purchased from three representative wholesale markets within or nearby to Bangkok. All fish species were prepared to determine their edible portions (EP) and moisture contents. Total Se in fresh, boiled, and fried fish were analysed using Inductively Coupled Plasma-Triple Quadrupole-Mass Spectrometry (ICP-QQQ-MS). In general, higher levels of Se were found in marine fish (37.1–198.5 µg/100 g EP in fresh fish, 48.0–154.4 µg/100 g EP in boiled fish, and 52.9–262.4 µg/100 g EP in fried fish) compared to freshwater fish (6.9–29.4 µg/100 g EP in fresh fish, 10.1–26.5 µg/100 g EP in boiled fish, and 13.7–43.8 µg/100 g EP in fried fish...
HIV & AIDS Review, 2017
Human immunodeficiency virus (HIV) infection largely impacts on the nutritional status of infecte... more Human immunodeficiency virus (HIV) infection largely impacts on the nutritional status of infected patients. At present, advance in medicine and pharmaceuticals such as antiretroviral drugs help improve health status among people living with HIV (PLHIV). Improving appetite for PLHIV by regaining their normal taste sensation and enhanced naso-oral stimulation can help promote their consumption of larger amounts of food. Previous studies have shown how bad HIV infection affects mental status, which leads to the development of many health problems including eating disorder. This is a cross-sectional study aimed to investigate characteristics of food consumed by PLHIV and comparing that between high-risk and low-risk eating disorder groups. The developed self-respondent questionnaires (baseline questionnaire, eating disorder screening questionnaire, self-adherence questionnaire, and 3-day food record) were completed by 132 HIV infected patients at the Queen Savang Vadhana Memorial Hospital, Chonburi province. The results in a high-risk group were not significant on energy distribution (carbohydrate, protein, fat) compared with a low-risk group, but the data indicated that the high-risk group had a significantly higher intake of saturated fat and sodium compared with the low-risk group. In addition, results indicated that the high-risk group was significantly lower in self-adherent score and CD4 level compared with the low-risk group.
ผลของการดมชาใบหมอนตอระดบนำตาลในเลอดและระดบความอมในอาสาสมครสขภาพด อไรภรณ บรณสขสกล*, อลงกต สงหโต, น... more ผลของการดมชาใบหมอนตอระดบนำตาลในเลอดและระดบความอมในอาสาสมครสขภาพด อไรภรณ บรณสขสกล*, อลงกต สงหโต, นรศา เรองศร, ปยะพงษ ประเสรฐศร คณะสหเวชศาสตร มหาวทยาลยบรพา หลกการและวตถประสงค : ใบหมอน (Morus alba) มสารตานอนมลอสระสง ไดแก สารกลมฟลาโวนอยด (flavonoids) และ 1-deoxynojirimycin (DNJ) ซงเปนสารกลม alpha-glucosidase inhibitor มฤทธในการลดระดบนำตาลในเลอด การศกษากอนหนาพบวาในใบหมอนสายพนธบรรมย 60 มสาร DNJ สงกวาสายพนธอน การศกษาครงนจงมวตถประสงคเพอศกษาผลของการดมชาใบหมอนสายพนธบรรมย 60 ตอระดบนำตาลในเลอดและความอม วธการศกษา : เปนการศกษาแบบไขวเชงสมในอาสาสมครสขภาพดในมหาวทยาลยบรพา จำนวน 12 ราย อาย 20-23 ป แบงเปนกลมควบคมและกลมทดลองโดยแตละกลมใชอาสาสมครชดเดยวกน แตเวนชวงทดลองหางกน 1 สปดาห ทงสองกลมไดดมเครองดมวจย 2 ชนด ประกอบดวย ชาใบหมอนสายพนธบรรมย 60 (กลมทดลอง) และนำอน (กลมควบคม) หลงจากดมสารละลายกลโคส เปนเวลา 15 นาท ทำการตรวจวดระดบนำตาลในเลอด ระดบความอม ระดบความดนโลหต อตราการเตนของหวใจ อณหภมกาย และการทำงานของระบบประสาทอตโนมต กอนดม (นาทท 0) และหลงดมในนาทท 30, 60, 90 และ 120 ผลการศกษา : ระดบนำตาลในเลอดของอาสาสมครกลม...
Annals of Nutrition and Metabolism, 2020
Introduction: Previous studies have established the risk of bone loss among people living with HI... more Introduction: Previous studies have established the risk of bone loss among people living with HIV affected by antiretroviral therapy drug side effects and inadequate nutrient intake. Until recently, there have been limits on using the medical nutrition therapy (MNT) to improve dietary habits for promoting bone health among people living with HIV. This was a randomized controlled trial study aimed to investigate the effectiveness of MNT in improving the bone health in people living with HIV by promoting dietary habits. Methods: PLHIV at Queen Savang Vadhana Memorial Hospital were randomly grouped (by quota sampling) into the MNT group (intervention group) and the control group. One hundred and thirty PLHIV were recruited to participate in this study by convenient sampling. Sixty-five participants of the MNT group made a total of 6 appointments (for 12 weeks) to meet registered dietitians for receiving MNT to improve dietary habits for improving bone health, while 65 participants in ...
Current Research in Nutrition and Food Science Journal, 2018
People living with HIV (PLHIV) with oral problems usually suffer from malnutrition due to difficu... more People living with HIV (PLHIV) with oral problems usually suffer from malnutrition due to difficulties in chewing and swallowing, which lead to under nutrition. In addition, hyperglycemia is one of the major problems among PLHIV receiving antiretroviral therapy (ART).Up to now, in Thailand there is still a lack of specialized food products for PLHIV with oral problems that can be easily chewed and swallowed to prevent their malnutrition.This study aimed to develop high protein food products in the form of snack with artificial sweeteners, and to determine the levels of acceptance (taste, flavor, color, texture and overall satisfaction) by PLHIV with oral problems. Soybean milk pudding was selected as the food product since it is the most favored snack among PLHIV. All 3 high protein snacks (containing sugar, sucralose, and stevioside) were developed for 30 PLHIV with oral problems, and their sensory perceptions were evaluated. Results revealed there were no significant differences i...
Current Research in Nutrition and Food Science Journal, 2018
High prevalence of chronic kidney disease has been reported in Thailand, and patients with this c... more High prevalence of chronic kidney disease has been reported in Thailand, and patients with this chronic disease need to restrict their dietary protein intakes because of their low glomerular filtration rate, including those from rice and starch. Unfortunately, there is a lack of protein-free starch available in Thai communities. Therefore, this study aimed to develop protein-free starchy products that were used as ingredients in Thai ethnic food menus. Five menus (Pad See Ew, Rad Na, Pad Thai, Kuay Jub, and Pad Kee Mao) incorporating the developed protein-free starchy products (with 3 formulae using the developed starchy products and 1 original formula per menu) were developed for conducting the sensory evaluation by 48 healthy participants. Results revealed all menus showed significant difference of satisfaction scores on food texture (p<0.05). In addition, Pad Se Ew, Pad Thai (formula 1), and Pad Kee Mao (all formulae) had the overall satisfaction scores at acceptable level. In...
Foods
Selenium (Se), abundantly obtained in fish, is a crucial trace element for human health. Since th... more Selenium (Se), abundantly obtained in fish, is a crucial trace element for human health. Since there are no data on Se bioaccessibility from commonly consumed fish in Thailand, this study assessed the in vitro bioaccessibility of Se using the equilibrium dialyzability method. The five fish species most commonly consumed in Thailand were selected to determine total Se content using several preparation methods (fresh, boiling, and frying). Equilibrium dialyzability was used to perform in vitro bioaccessibility using enzymatic treatment to simulate gastrointestinal digestion for all boiled and fried fish as well as measuring Se using inductively coupled plasma triple quadrupole mass spectrometry (ICP-QQQ-MS). Two-way ANOVA with interaction followed by Tukey’s honestly significant difference (HSD) post hoc test revealed that boiled Indo-Pacific Spanish mackerel, longtail tuna, and short-bodied mackerel were significantly higher in Se content than striped snakehead and giant sea perch (p...
The American Journal of Medicine, 2008
OBJECTIVE-Alcoholism is a risk factor for osteoporotic fractures and low bone density, but the ef... more OBJECTIVE-Alcoholism is a risk factor for osteoporotic fractures and low bone density, but the effects of moderate alcohol consumption on bone are unknown. We performed a systematic review and meta-analysis to assess the associations between alcohol consumption and osteoporotic fractures, bone density and bone density loss over time, bone response to estrogen replacement, and bone remodeling. METHODS-MEDLINE, Current Contents, PsychINFO, and Cochrane Libraries were searched for studies published before May 14, 2007. We assessed quality using the internal validity criteria of the US Preventive Services Task Force. RESULTS-We pooled effect sizes for 2 specific outcomes (hip fracture and bone density) and synthesized data qualitatively for 4 outcomes (non-hip fracture, bone density loss over time, bone response to estrogen replacement, and bone remodeling). Compared with abstainers, persons consuming from more than 0.5 to 1.0 drinks per day had lower hip fracture risk (relative risk = 0.80 risk [95% confidence interval, 0.71-0.91]), and persons consuming more than 2 drinks per day had higher risk (relative risk = 1.39 [95% risk confidence interval, 1.08-1.79]). A linear relationship existed between femoral neck bone density and alcohol consumption. Because studies often combined moderate and heavier drinkers in a single category, we could not assess relative associations between alcohol consumption and bone density in moderate compared with heavy drinkers. CONCLUSION-Compared with abstainers and heavier drinkers, persons who consume 0.5 to 1.0 drink per day have a lower risk of hip fracture. Although available evidence suggests a favorable effect of alcohol consumption on bone density, a precise range of beneficial alcohol consumption cannot be determined.
Journal of Food Composition and Analysis
Foods
Although fish are good sources of selenium (Se), an essential trace element for the human body, v... more Although fish are good sources of selenium (Se), an essential trace element for the human body, very limited data exist on Se content in commonly consumed fish in Thailand. Consequently, this study investigated selenium content and the effect of cooking among 10 fish species (5 freshwater and 5 marine) most-commonly consumed by the Thai people. The fish were purchased from three representative wholesale markets within or nearby to Bangkok. All fish species were prepared to determine their edible portions (EP) and moisture contents. Total Se in fresh, boiled, and fried fish were analysed using Inductively Coupled Plasma-Triple Quadrupole-Mass Spectrometry (ICP-QQQ-MS). In general, higher levels of Se were found in marine fish (37.1–198.5 µg/100 g EP in fresh fish, 48.0–154.4 µg/100 g EP in boiled fish, and 52.9–262.4 µg/100 g EP in fried fish) compared to freshwater fish (6.9–29.4 µg/100 g EP in fresh fish, 10.1–26.5 µg/100 g EP in boiled fish, and 13.7–43.8 µg/100 g EP in fried fish...
HIV & AIDS Review, 2017
Human immunodeficiency virus (HIV) infection largely impacts on the nutritional status of infecte... more Human immunodeficiency virus (HIV) infection largely impacts on the nutritional status of infected patients. At present, advance in medicine and pharmaceuticals such as antiretroviral drugs help improve health status among people living with HIV (PLHIV). Improving appetite for PLHIV by regaining their normal taste sensation and enhanced naso-oral stimulation can help promote their consumption of larger amounts of food. Previous studies have shown how bad HIV infection affects mental status, which leads to the development of many health problems including eating disorder. This is a cross-sectional study aimed to investigate characteristics of food consumed by PLHIV and comparing that between high-risk and low-risk eating disorder groups. The developed self-respondent questionnaires (baseline questionnaire, eating disorder screening questionnaire, self-adherence questionnaire, and 3-day food record) were completed by 132 HIV infected patients at the Queen Savang Vadhana Memorial Hospital, Chonburi province. The results in a high-risk group were not significant on energy distribution (carbohydrate, protein, fat) compared with a low-risk group, but the data indicated that the high-risk group had a significantly higher intake of saturated fat and sodium compared with the low-risk group. In addition, results indicated that the high-risk group was significantly lower in self-adherent score and CD4 level compared with the low-risk group.
ผลของการดมชาใบหมอนตอระดบนำตาลในเลอดและระดบความอมในอาสาสมครสขภาพด อไรภรณ บรณสขสกล*, อลงกต สงหโต, น... more ผลของการดมชาใบหมอนตอระดบนำตาลในเลอดและระดบความอมในอาสาสมครสขภาพด อไรภรณ บรณสขสกล*, อลงกต สงหโต, นรศา เรองศร, ปยะพงษ ประเสรฐศร คณะสหเวชศาสตร มหาวทยาลยบรพา หลกการและวตถประสงค : ใบหมอน (Morus alba) มสารตานอนมลอสระสง ไดแก สารกลมฟลาโวนอยด (flavonoids) และ 1-deoxynojirimycin (DNJ) ซงเปนสารกลม alpha-glucosidase inhibitor มฤทธในการลดระดบนำตาลในเลอด การศกษากอนหนาพบวาในใบหมอนสายพนธบรรมย 60 มสาร DNJ สงกวาสายพนธอน การศกษาครงนจงมวตถประสงคเพอศกษาผลของการดมชาใบหมอนสายพนธบรรมย 60 ตอระดบนำตาลในเลอดและความอม วธการศกษา : เปนการศกษาแบบไขวเชงสมในอาสาสมครสขภาพดในมหาวทยาลยบรพา จำนวน 12 ราย อาย 20-23 ป แบงเปนกลมควบคมและกลมทดลองโดยแตละกลมใชอาสาสมครชดเดยวกน แตเวนชวงทดลองหางกน 1 สปดาห ทงสองกลมไดดมเครองดมวจย 2 ชนด ประกอบดวย ชาใบหมอนสายพนธบรรมย 60 (กลมทดลอง) และนำอน (กลมควบคม) หลงจากดมสารละลายกลโคส เปนเวลา 15 นาท ทำการตรวจวดระดบนำตาลในเลอด ระดบความอม ระดบความดนโลหต อตราการเตนของหวใจ อณหภมกาย และการทำงานของระบบประสาทอตโนมต กอนดม (นาทท 0) และหลงดมในนาทท 30, 60, 90 และ 120 ผลการศกษา : ระดบนำตาลในเลอดของอาสาสมครกลม...
Annals of Nutrition and Metabolism, 2020
Introduction: Previous studies have established the risk of bone loss among people living with HI... more Introduction: Previous studies have established the risk of bone loss among people living with HIV affected by antiretroviral therapy drug side effects and inadequate nutrient intake. Until recently, there have been limits on using the medical nutrition therapy (MNT) to improve dietary habits for promoting bone health among people living with HIV. This was a randomized controlled trial study aimed to investigate the effectiveness of MNT in improving the bone health in people living with HIV by promoting dietary habits. Methods: PLHIV at Queen Savang Vadhana Memorial Hospital were randomly grouped (by quota sampling) into the MNT group (intervention group) and the control group. One hundred and thirty PLHIV were recruited to participate in this study by convenient sampling. Sixty-five participants of the MNT group made a total of 6 appointments (for 12 weeks) to meet registered dietitians for receiving MNT to improve dietary habits for improving bone health, while 65 participants in ...
Current Research in Nutrition and Food Science Journal, 2018
People living with HIV (PLHIV) with oral problems usually suffer from malnutrition due to difficu... more People living with HIV (PLHIV) with oral problems usually suffer from malnutrition due to difficulties in chewing and swallowing, which lead to under nutrition. In addition, hyperglycemia is one of the major problems among PLHIV receiving antiretroviral therapy (ART).Up to now, in Thailand there is still a lack of specialized food products for PLHIV with oral problems that can be easily chewed and swallowed to prevent their malnutrition.This study aimed to develop high protein food products in the form of snack with artificial sweeteners, and to determine the levels of acceptance (taste, flavor, color, texture and overall satisfaction) by PLHIV with oral problems. Soybean milk pudding was selected as the food product since it is the most favored snack among PLHIV. All 3 high protein snacks (containing sugar, sucralose, and stevioside) were developed for 30 PLHIV with oral problems, and their sensory perceptions were evaluated. Results revealed there were no significant differences i...
Current Research in Nutrition and Food Science Journal, 2018
High prevalence of chronic kidney disease has been reported in Thailand, and patients with this c... more High prevalence of chronic kidney disease has been reported in Thailand, and patients with this chronic disease need to restrict their dietary protein intakes because of their low glomerular filtration rate, including those from rice and starch. Unfortunately, there is a lack of protein-free starch available in Thai communities. Therefore, this study aimed to develop protein-free starchy products that were used as ingredients in Thai ethnic food menus. Five menus (Pad See Ew, Rad Na, Pad Thai, Kuay Jub, and Pad Kee Mao) incorporating the developed protein-free starchy products (with 3 formulae using the developed starchy products and 1 original formula per menu) were developed for conducting the sensory evaluation by 48 healthy participants. Results revealed all menus showed significant difference of satisfaction scores on food texture (p<0.05). In addition, Pad Se Ew, Pad Thai (formula 1), and Pad Kee Mao (all formulae) had the overall satisfaction scores at acceptable level. In...
Foods
Selenium (Se), abundantly obtained in fish, is a crucial trace element for human health. Since th... more Selenium (Se), abundantly obtained in fish, is a crucial trace element for human health. Since there are no data on Se bioaccessibility from commonly consumed fish in Thailand, this study assessed the in vitro bioaccessibility of Se using the equilibrium dialyzability method. The five fish species most commonly consumed in Thailand were selected to determine total Se content using several preparation methods (fresh, boiling, and frying). Equilibrium dialyzability was used to perform in vitro bioaccessibility using enzymatic treatment to simulate gastrointestinal digestion for all boiled and fried fish as well as measuring Se using inductively coupled plasma triple quadrupole mass spectrometry (ICP-QQQ-MS). Two-way ANOVA with interaction followed by Tukey’s honestly significant difference (HSD) post hoc test revealed that boiled Indo-Pacific Spanish mackerel, longtail tuna, and short-bodied mackerel were significantly higher in Se content than striped snakehead and giant sea perch (p...