Alper Kararmaz - Academia.edu (original) (raw)
Papers by Alper Kararmaz
A Rare Complication of Amiodarone: Diffuse Alveolar HemorrhageAmiodarone, a frequently used antia... more A Rare Complication of Amiodarone: Diffuse Alveolar HemorrhageAmiodarone, a frequently used antiarrhythmic drug is known for having neurological, ophthalmic, cutaneous, hepatic and pulmonary side effects. Signs of pulmonary toxicity are observed dependent on the duration of exposure and the dose administered. Pulmonary complications occur in 10-17 % patients and interstitial pneumonia is the most common one. In this case report we present a female patient with acute atrial fibrillation associated with rapid ventricular response treated with amiodarone who developed diffuse alveolar hemorrhage, a rare complication of amiodarone.
Acta Chirurgica Belgica, 2019
Background: We investigated whether cardiopulmonary bypass (CPB) related oxidative stress mediate... more Background: We investigated whether cardiopulmonary bypass (CPB) related oxidative stress mediated glycocalyx degradation can cause an increase in renal resistive index (RRI) or postoperative AKI. Additionally, to evaluate whether RRI and early postoperative serum cystatin C levels could improve the prediction sensitivity of acute kidney injury (AKI). Methods: Forty-two patients undergoing cardiac surgery were included in this prospective observational study. RRI was measured pre-operatively and in the cardiac intensive care unit. Blood samples were collected for analyzing of cellular injury biomarkers at preoperative and postoperative second hours. We determined areas under the receiver operating characteristic curve (AUC) and odds ratios for postoperative biomarkers and RRI to predict AKI. Results: While postoperative cystatin C level (AUC: 0.902, 95% CI ¼ 0.79-1.00, p < .001) and RRI (AUC: 0.748, 95% CI ¼ 0.56-0.93, p ¼ .023) have diagnostic and predictive value in the prediction of AKI, we could not identify any relation between products of oxidative stress and the glycocalyx degradation and AKI. Conclusion: These data suggest that CPB leads to structural and oxidative changes at the protein level and the integrity of glycocalyx is disturbing, but these changes are not specific to kidney injury. Our data suggest that serum cystatin C level and RRI could be used as an early biomarker for postoperative AKI after cardiac surgery.
The Internet Journal of Emergency and Intensive Care Medicine, 2006
Acute chest syndrome is a serious complication and one of the causes of mortality in sickle cell ... more Acute chest syndrome is a serious complication and one of the causes of mortality in sickle cell disease. Seventeen years-old male was admitted to hematology clinic with acute chest pain and hemolytic crisis. He was treated with intravenous fluid and nasal oxygen supplementation. Chest pain was sustained and brain confusion with severe hypoxemia developed after 12 hours of hospitalization. The patient was transferred suddenly to intensive care unit of our hospital. Endotracheal intubation and mechanical ventilation was initiated. In spite of respiratory and medical support, his medical status worsened, so red cell exchange transfusion was made. Brain functions, other vital parameters, and organ functions were turned to normal after treatment. We conclude that the physician should be alert if the patient with sickle cell disease being hypoxic and we believe that red cell exchange transfusion is effective treatment modality in these patients.
Intensive Care Medicine Experimental, 2015
Venous air embolism is a complication with high mortality and morbidity which may occur in neuros... more Venous air embolism is a complication with high mortality and morbidity which may occur in neurosurgical operations especially in patients with semi-sitting, sitting and even supine position.In a patient who underwent surgery because of a glial tumour located in the parietal lobe end tidal CO2, O2 saturation and systemic blood pressure decreased suddenly during the operation. The aeration of the left lung was restricted and a pansystolic cardiac murmur was auscultated. Air was aspirated from the central catheter of the patient who was thought to have developed venous air embolism and hemodynamic stability was reassured. At the end of the operation the patient was awaken and extubated. In this case the potential complications were prevented by standard optimum monitoring and early intervention. The aim of this case report is to remind the close follow up of the patients undergoing neurosurgical operations in semi-sitting, sitting or supine positions by central venous catheterization ...
The Journal of Thoracic and Cardiovascular Surgery, 2015
Medical science monitor : international medical journal of experimental and clinical research, 2009
The aim was to investigate the effect of magnesium sulfate on postoperative pain and analgesic co... more The aim was to investigate the effect of magnesium sulfate on postoperative pain and analgesic consumption after remifentanil-based anesthesia. Forty women 18 to 65 years old were enrolled in this prospective, randomized, double-blinded clinical study. The study solutions were randomly preoperatively prepared for groups M (magnesium) and R (normal saline). A bolus of 0.2 ml/kg of study solution (30 mg/kg magnesium or saline) was given before induction of anesthesia and infusion was started at a rate of 3.3 ml/h (500 mg/h magnesium or saline). A 1 microg/kg loading dose of remifentanil following infusion was started at a rate of 0.25 micro g/kg/min, subsequently increasing stepwise by 0.05 micro g/kg/min increments if insufficient anesthesia was suspected. All postoperative outcome data were collected by an anesthesiologist who was blinded to the anesthetic regimen. Pain intensity using a visual analogue scale (VAS) was recorded for 24 hours postoperatively. Hemodynamic and respirato...
Aǧrı : Ağrı (Algoloji) Derneği'nin Yayın organıdır = The journal of the Turkish Society of Algology, 2004
We aimed to assess the efficacy of multimodal epidural analgesia in decreasing postoperative pain... more We aimed to assess the efficacy of multimodal epidural analgesia in decreasing postoperative pain after microdiscectomy. Fourty patients, ASA physical status I or II, undergoing microsurgical lumbar discectomy were enrolled in this prospective, randomised, controlled, double-blinded study. 10 ml study solution consisting of 2 mg of morphine, 15 mg of bupivacaine, 80 mg of methylprednisolone, and 0.05 mg of adrenaline was prepared for epidural administration. At the end of the procedure but prior to wound closure, the surgeon inserted an 18-gauge epidural catheter into the epidural space. After closure of incision, patients were assigned to receive either study solution (Group E) or saline (Group C). The epidural catheter was then removed. Patient controlled analgesia with morphine was used for postoperative analgesia. Visual Anologue Scale (VAS) pain scores and morphine consumptions were lower in Group E. Time to first ambulation was shorter in Group E. Patients in Group E were more...
Journal of Cardiothoracic and Vascular Anesthesia, 2015
The aim of this study was to evaluate the relationship between transesophageal ultrasonographyder... more The aim of this study was to evaluate the relationship between transesophageal ultrasonographyderived renal resistive index values (RRI TEE) and a standard translumbar renal ultrasound-derived RRI (RRI TLUSG). The effectiveness of each method to predict acute kidney injury (AKI) after cardiac surgery also was compared. Design: A prospective observational study. Setting: A teaching university hospital. Participants: Sixty patients undergoing cardiac surgery. Interventions: First, RRI was measured with both methods after anesthesia induction. Second, another measurement was performed with TEE after cardiopulmonary bypass and immediately following the surgery with translumbar ultrasound. To test the correlation between the 2 methods and to plot a Bland-Altman graph, preoperative RRI values measured by both techniques were used. Receiver operating characteristic curves also were plotted to compare the diagnostic values of RRI measured intraoperatively by TEE after cardiopulmonary bypass and by RRI TLUSG after surgery. Measurements and Main Results: There was a statistically significant correlation between the 2 RRI measurement approaches (r ¼ 0.86, p o 0.0001). The Bland-Altman plot indicated good agreement between the methods. The area under the curve (AUC) of RRI TEE in predicting AKI was 0.82 (95% confidence interval [CI] ¼ 0.64-0.9, p ¼ 0.001), and the AUC of RRI TLUSG after surgery was 0.85 (95% CI ¼ 0.7-0.98, p o 0.0001). In predicting AKI, an uncertainty zone for RRI TEE values between 0.68 and 0.71 was computed by the gray-zone approach. Conclusions: RRI TEE showed clinically acceptable agreement with RRI TLUSG. Indeed, RRI measured intraoperatively with TEE was comparable to RRI TLUSG in terms of detecting postoperative AKI.
Journal of Cardio-Vascular-Thoracic Anaesthesia and Intensive Care Society, 2014
Antiaritmik olarak sıkça kullanılan bir ilaç olan amiodaronun nörolojik, oftalmik, kutanöz, hepat... more Antiaritmik olarak sıkça kullanılan bir ilaç olan amiodaronun nörolojik, oftalmik, kutanöz, hepatik ve pulmoner yan etkileri bilinmektedir. Kullanım süresi ve miktarına bağlı olarak pulmoner toksisite bulguları gözlenir. Pulmoner yan etkiler % 10-17 oranında görülür ve genellikle interstisiyel pnömoni şeklindedir. Bu olgu sunumunda, hızlı ventrikül cevaplı akut atrial fibrilasyon nedeniyle amiodaron tedavisi başlanan bayan hastada amiodaronun ender bir komplikasyonu olan yaygın alveolar hemoraji irdelenmiştir.
Angiology: Open Access, 2014
Journal of Musculoskeletal Pain, 2008
The objectives of this study were to determine the prevalence of the fibromyalgia syndrome [FMS] ... more The objectives of this study were to determine the prevalence of the fibromyalgia syndrome [FMS] in Diyarbakir, a city located in the southeastern region of Turkey, and to evaluate associated demographic variables. Methods: This study was conducted in the beginning of 2003. A total of 600 people, randomly selected by stratified cluster sampling, were interviewed in person using a questionnaire consisting of demographic features and history of chronic widespread pain. Individuals with chronic widespread pain were examined by a specialist in physical medicine and rehabilitation in order to confirm or exclude FMS based on the American College of Rheumatology classification criteria. The statistical analysis was performed by using a package program called Epi Info 2000. Results: Fifty-three people were diagnosed with FMS. Based on the study results, the prevalence of FMS was 8.8 percent in our regional study group. The prevalence was higher in women
Journal of Clinical Anesthesia, 2007
To determine whether intravenous injection of lornoxicam 30 minutes before skin incision provides... more To determine whether intravenous injection of lornoxicam 30 minutes before skin incision provides better pain relief after varicocelectomy than postoperative administration of lornoxicam. Prospective, double-blind, randomized clinical investigation. Operating room and postoperative recovery area. 44 ASA physical status I and II adult male patients undergoing varicocelectomy. Patients were randomized either to receive 8 mg lornoxicam infusion 30 minutes before skin incision, followed by saline infusion immediately after skin closure (group 1), or to receive the identical injections but in reverse order (group 2). All patients received local anesthesia with bupivacaine. Postoperative pain scores were evaluated hourly for the first 8 hours after surgery, then at 12, 16, 20, and 24 hours after surgery, using a 10-cm visual analog scale. Time to first analgesic request and patients&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39; global assessments also were recorded. Patients in group 1 reported significantly lower pain scores (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05) at all time intervals except at 24 hours and better global assessment (P = 0.001) than did group 2. There were significantly fewer patients in the preemptive group than group 2 who required rescue analgesic within the first 24 hours (0% vs 22.7%; P = 0.024). Mean time to first analgesic request was also significantly longer in the preemptive group (P = 0.001). Intravenous lornoxicam administered before surgery has a better analgesic effect for varicocelectomy than when administered postoperatively.
Journal of Cardiac Surgery, 2014
In this paper, we report an alternative approach for implantation of ventricular pacing lead for ... more In this paper, we report an alternative approach for implantation of ventricular pacing lead for complete atrioventricular block after tricuspid valve replacement.
European Journal of Anaesthesiology, 2003
Backgroundandobjective: A need exists for a safe and effective oral preanaesthetic medication for... more Backgroundandobjective: A need exists for a safe and effective oral preanaesthetic medication for use in children undergoing elective surgery. The study sought to define the dose of oral ketamine that would facilitate induction of anaesthesia without causing significant side-effects. Method: We studied 80 children undergoing elective surgery under general anaesthesia who received oral ketamine 4,G or 8 mg kg-' in a prospective, randomized, double-blind placebo controlled study. We compared the reaction to separation from parents, transport to the operating room, the response to intravenous cannula insertion and application of an anaesthetic facemask, the induction of anaesthesia and recovery from anaesthesia. Resnlts: In the group receiving ketamine 8 mg kg-', the children were significantly calmer than those of the other groups, and anaesthesia induction was more comfortable. Recovery from anaesthesia was longer in the group receiving ketamine 8 mg kg-' compared with the other groups, but no differences between the groups were observed after 2 h in the recovery room. Conclusions: It is concluded that oral ketamine 8 mg kg-' is an effective oral premedication in inpatient children undergoing elective surgery.
dicle.edu.tr
... Mustafa Kemal Üniversitesi Tayfur Ata Sökmen Tıp Fakültesi Anesteziyoloji ve Reanimasyon AD .... more ... Mustafa Kemal Üniversitesi Tayfur Ata Sökmen Tıp Fakültesi Anesteziyoloji ve Reanimasyon AD ... B.Çağla Özbakış Akkurt, Kerem İnanoğlu, Olgun Karazincir, Alper Kararmaz, Selim ... ve hatta supin pozisyonlarda oluşabilen sonucunda morbidite ve mortalitesi yüksek olan bir ...
firattipdergisi.com
ÖZET Amaç: Çalışmamızda levobupivakaine eklenen fentanil ile elde edilen hipobarik solüsyon ile y... more ÖZET Amaç: Çalışmamızda levobupivakaine eklenen fentanil ile elde edilen hipobarik solüsyon ile yapılan spinal anestezinin farklı hasta pozisyonlarında blok karakteristikleri üzerine ve hemodinamik parametreler üzerine olan etkisini araştırmayı amaçladık. Gereç ve Yöntem: Elektif şartlarda artroskopik girişim planlanan ASA I-II grubu 40 hasta rastgele iki eşit gruba ayrıldı. Hastalara oturur pozisyonda, L 3-4 aralığından 25 Gouge spinal iğne ile girilerek 1.5 ml (7.5 mg) %0.5 levobupivakain ve 0.5 ml (25µ) fentanil verilerek spinal anestezi uygulandı. GRUP I'deki hastalara uygulama sonrası hemen sırt üstü pozisyon verilirken, GRUP II'deki hastalar 45º oturur pozisyona alındı. Duyusal blok seviyesi pinpirik testi ile, motor blok seviyesi ise Bromage skalası ile ilk 15 dk.her 2.5 dk'da, sonraki 15 dk her 5 dk'da bir ve 1.,2.,3.,4. saatlerde değerlendirildi ve kaydedildi. Bulgular: Demografik veriler ve hemodinamik parametreler açısından iki grup arasında anlamlı bir fark yoktu (p> 0.05). Duyusal blok seviyesi, motor blok seviyesi, maksimum duyu bloğu seviyesi ve oluşma zamanı, iki segment regresyon zamanı ve S1 segmente gerileme zamanı iki grup arasında karşılaştırıldığında istatistiksel olarak anlamlı fark saptanmadı (p>0.05). Sonuç: Hipobarik levobupivakain+ fentanil karışımı ile yapılan spinal anestezide supin ve 45 derece oturur pozisyonların, hemodinamik parametreler ile duyusal ve motor blok düzeyleri üzerine anlamlı bir fark oluşturacak düzeyde etki etmediği sonucuna vardık.
A Rare Complication of Amiodarone: Diffuse Alveolar HemorrhageAmiodarone, a frequently used antia... more A Rare Complication of Amiodarone: Diffuse Alveolar HemorrhageAmiodarone, a frequently used antiarrhythmic drug is known for having neurological, ophthalmic, cutaneous, hepatic and pulmonary side effects. Signs of pulmonary toxicity are observed dependent on the duration of exposure and the dose administered. Pulmonary complications occur in 10-17 % patients and interstitial pneumonia is the most common one. In this case report we present a female patient with acute atrial fibrillation associated with rapid ventricular response treated with amiodarone who developed diffuse alveolar hemorrhage, a rare complication of amiodarone.
Acta Chirurgica Belgica, 2019
Background: We investigated whether cardiopulmonary bypass (CPB) related oxidative stress mediate... more Background: We investigated whether cardiopulmonary bypass (CPB) related oxidative stress mediated glycocalyx degradation can cause an increase in renal resistive index (RRI) or postoperative AKI. Additionally, to evaluate whether RRI and early postoperative serum cystatin C levels could improve the prediction sensitivity of acute kidney injury (AKI). Methods: Forty-two patients undergoing cardiac surgery were included in this prospective observational study. RRI was measured pre-operatively and in the cardiac intensive care unit. Blood samples were collected for analyzing of cellular injury biomarkers at preoperative and postoperative second hours. We determined areas under the receiver operating characteristic curve (AUC) and odds ratios for postoperative biomarkers and RRI to predict AKI. Results: While postoperative cystatin C level (AUC: 0.902, 95% CI ¼ 0.79-1.00, p < .001) and RRI (AUC: 0.748, 95% CI ¼ 0.56-0.93, p ¼ .023) have diagnostic and predictive value in the prediction of AKI, we could not identify any relation between products of oxidative stress and the glycocalyx degradation and AKI. Conclusion: These data suggest that CPB leads to structural and oxidative changes at the protein level and the integrity of glycocalyx is disturbing, but these changes are not specific to kidney injury. Our data suggest that serum cystatin C level and RRI could be used as an early biomarker for postoperative AKI after cardiac surgery.
The Internet Journal of Emergency and Intensive Care Medicine, 2006
Acute chest syndrome is a serious complication and one of the causes of mortality in sickle cell ... more Acute chest syndrome is a serious complication and one of the causes of mortality in sickle cell disease. Seventeen years-old male was admitted to hematology clinic with acute chest pain and hemolytic crisis. He was treated with intravenous fluid and nasal oxygen supplementation. Chest pain was sustained and brain confusion with severe hypoxemia developed after 12 hours of hospitalization. The patient was transferred suddenly to intensive care unit of our hospital. Endotracheal intubation and mechanical ventilation was initiated. In spite of respiratory and medical support, his medical status worsened, so red cell exchange transfusion was made. Brain functions, other vital parameters, and organ functions were turned to normal after treatment. We conclude that the physician should be alert if the patient with sickle cell disease being hypoxic and we believe that red cell exchange transfusion is effective treatment modality in these patients.
Intensive Care Medicine Experimental, 2015
Venous air embolism is a complication with high mortality and morbidity which may occur in neuros... more Venous air embolism is a complication with high mortality and morbidity which may occur in neurosurgical operations especially in patients with semi-sitting, sitting and even supine position.In a patient who underwent surgery because of a glial tumour located in the parietal lobe end tidal CO2, O2 saturation and systemic blood pressure decreased suddenly during the operation. The aeration of the left lung was restricted and a pansystolic cardiac murmur was auscultated. Air was aspirated from the central catheter of the patient who was thought to have developed venous air embolism and hemodynamic stability was reassured. At the end of the operation the patient was awaken and extubated. In this case the potential complications were prevented by standard optimum monitoring and early intervention. The aim of this case report is to remind the close follow up of the patients undergoing neurosurgical operations in semi-sitting, sitting or supine positions by central venous catheterization ...
The Journal of Thoracic and Cardiovascular Surgery, 2015
Medical science monitor : international medical journal of experimental and clinical research, 2009
The aim was to investigate the effect of magnesium sulfate on postoperative pain and analgesic co... more The aim was to investigate the effect of magnesium sulfate on postoperative pain and analgesic consumption after remifentanil-based anesthesia. Forty women 18 to 65 years old were enrolled in this prospective, randomized, double-blinded clinical study. The study solutions were randomly preoperatively prepared for groups M (magnesium) and R (normal saline). A bolus of 0.2 ml/kg of study solution (30 mg/kg magnesium or saline) was given before induction of anesthesia and infusion was started at a rate of 3.3 ml/h (500 mg/h magnesium or saline). A 1 microg/kg loading dose of remifentanil following infusion was started at a rate of 0.25 micro g/kg/min, subsequently increasing stepwise by 0.05 micro g/kg/min increments if insufficient anesthesia was suspected. All postoperative outcome data were collected by an anesthesiologist who was blinded to the anesthetic regimen. Pain intensity using a visual analogue scale (VAS) was recorded for 24 hours postoperatively. Hemodynamic and respirato...
Aǧrı : Ağrı (Algoloji) Derneği'nin Yayın organıdır = The journal of the Turkish Society of Algology, 2004
We aimed to assess the efficacy of multimodal epidural analgesia in decreasing postoperative pain... more We aimed to assess the efficacy of multimodal epidural analgesia in decreasing postoperative pain after microdiscectomy. Fourty patients, ASA physical status I or II, undergoing microsurgical lumbar discectomy were enrolled in this prospective, randomised, controlled, double-blinded study. 10 ml study solution consisting of 2 mg of morphine, 15 mg of bupivacaine, 80 mg of methylprednisolone, and 0.05 mg of adrenaline was prepared for epidural administration. At the end of the procedure but prior to wound closure, the surgeon inserted an 18-gauge epidural catheter into the epidural space. After closure of incision, patients were assigned to receive either study solution (Group E) or saline (Group C). The epidural catheter was then removed. Patient controlled analgesia with morphine was used for postoperative analgesia. Visual Anologue Scale (VAS) pain scores and morphine consumptions were lower in Group E. Time to first ambulation was shorter in Group E. Patients in Group E were more...
Journal of Cardiothoracic and Vascular Anesthesia, 2015
The aim of this study was to evaluate the relationship between transesophageal ultrasonographyder... more The aim of this study was to evaluate the relationship between transesophageal ultrasonographyderived renal resistive index values (RRI TEE) and a standard translumbar renal ultrasound-derived RRI (RRI TLUSG). The effectiveness of each method to predict acute kidney injury (AKI) after cardiac surgery also was compared. Design: A prospective observational study. Setting: A teaching university hospital. Participants: Sixty patients undergoing cardiac surgery. Interventions: First, RRI was measured with both methods after anesthesia induction. Second, another measurement was performed with TEE after cardiopulmonary bypass and immediately following the surgery with translumbar ultrasound. To test the correlation between the 2 methods and to plot a Bland-Altman graph, preoperative RRI values measured by both techniques were used. Receiver operating characteristic curves also were plotted to compare the diagnostic values of RRI measured intraoperatively by TEE after cardiopulmonary bypass and by RRI TLUSG after surgery. Measurements and Main Results: There was a statistically significant correlation between the 2 RRI measurement approaches (r ¼ 0.86, p o 0.0001). The Bland-Altman plot indicated good agreement between the methods. The area under the curve (AUC) of RRI TEE in predicting AKI was 0.82 (95% confidence interval [CI] ¼ 0.64-0.9, p ¼ 0.001), and the AUC of RRI TLUSG after surgery was 0.85 (95% CI ¼ 0.7-0.98, p o 0.0001). In predicting AKI, an uncertainty zone for RRI TEE values between 0.68 and 0.71 was computed by the gray-zone approach. Conclusions: RRI TEE showed clinically acceptable agreement with RRI TLUSG. Indeed, RRI measured intraoperatively with TEE was comparable to RRI TLUSG in terms of detecting postoperative AKI.
Journal of Cardio-Vascular-Thoracic Anaesthesia and Intensive Care Society, 2014
Antiaritmik olarak sıkça kullanılan bir ilaç olan amiodaronun nörolojik, oftalmik, kutanöz, hepat... more Antiaritmik olarak sıkça kullanılan bir ilaç olan amiodaronun nörolojik, oftalmik, kutanöz, hepatik ve pulmoner yan etkileri bilinmektedir. Kullanım süresi ve miktarına bağlı olarak pulmoner toksisite bulguları gözlenir. Pulmoner yan etkiler % 10-17 oranında görülür ve genellikle interstisiyel pnömoni şeklindedir. Bu olgu sunumunda, hızlı ventrikül cevaplı akut atrial fibrilasyon nedeniyle amiodaron tedavisi başlanan bayan hastada amiodaronun ender bir komplikasyonu olan yaygın alveolar hemoraji irdelenmiştir.
Angiology: Open Access, 2014
Journal of Musculoskeletal Pain, 2008
The objectives of this study were to determine the prevalence of the fibromyalgia syndrome [FMS] ... more The objectives of this study were to determine the prevalence of the fibromyalgia syndrome [FMS] in Diyarbakir, a city located in the southeastern region of Turkey, and to evaluate associated demographic variables. Methods: This study was conducted in the beginning of 2003. A total of 600 people, randomly selected by stratified cluster sampling, were interviewed in person using a questionnaire consisting of demographic features and history of chronic widespread pain. Individuals with chronic widespread pain were examined by a specialist in physical medicine and rehabilitation in order to confirm or exclude FMS based on the American College of Rheumatology classification criteria. The statistical analysis was performed by using a package program called Epi Info 2000. Results: Fifty-three people were diagnosed with FMS. Based on the study results, the prevalence of FMS was 8.8 percent in our regional study group. The prevalence was higher in women
Journal of Clinical Anesthesia, 2007
To determine whether intravenous injection of lornoxicam 30 minutes before skin incision provides... more To determine whether intravenous injection of lornoxicam 30 minutes before skin incision provides better pain relief after varicocelectomy than postoperative administration of lornoxicam. Prospective, double-blind, randomized clinical investigation. Operating room and postoperative recovery area. 44 ASA physical status I and II adult male patients undergoing varicocelectomy. Patients were randomized either to receive 8 mg lornoxicam infusion 30 minutes before skin incision, followed by saline infusion immediately after skin closure (group 1), or to receive the identical injections but in reverse order (group 2). All patients received local anesthesia with bupivacaine. Postoperative pain scores were evaluated hourly for the first 8 hours after surgery, then at 12, 16, 20, and 24 hours after surgery, using a 10-cm visual analog scale. Time to first analgesic request and patients&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39; global assessments also were recorded. Patients in group 1 reported significantly lower pain scores (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05) at all time intervals except at 24 hours and better global assessment (P = 0.001) than did group 2. There were significantly fewer patients in the preemptive group than group 2 who required rescue analgesic within the first 24 hours (0% vs 22.7%; P = 0.024). Mean time to first analgesic request was also significantly longer in the preemptive group (P = 0.001). Intravenous lornoxicam administered before surgery has a better analgesic effect for varicocelectomy than when administered postoperatively.
Journal of Cardiac Surgery, 2014
In this paper, we report an alternative approach for implantation of ventricular pacing lead for ... more In this paper, we report an alternative approach for implantation of ventricular pacing lead for complete atrioventricular block after tricuspid valve replacement.
European Journal of Anaesthesiology, 2003
Backgroundandobjective: A need exists for a safe and effective oral preanaesthetic medication for... more Backgroundandobjective: A need exists for a safe and effective oral preanaesthetic medication for use in children undergoing elective surgery. The study sought to define the dose of oral ketamine that would facilitate induction of anaesthesia without causing significant side-effects. Method: We studied 80 children undergoing elective surgery under general anaesthesia who received oral ketamine 4,G or 8 mg kg-' in a prospective, randomized, double-blind placebo controlled study. We compared the reaction to separation from parents, transport to the operating room, the response to intravenous cannula insertion and application of an anaesthetic facemask, the induction of anaesthesia and recovery from anaesthesia. Resnlts: In the group receiving ketamine 8 mg kg-', the children were significantly calmer than those of the other groups, and anaesthesia induction was more comfortable. Recovery from anaesthesia was longer in the group receiving ketamine 8 mg kg-' compared with the other groups, but no differences between the groups were observed after 2 h in the recovery room. Conclusions: It is concluded that oral ketamine 8 mg kg-' is an effective oral premedication in inpatient children undergoing elective surgery.
dicle.edu.tr
... Mustafa Kemal Üniversitesi Tayfur Ata Sökmen Tıp Fakültesi Anesteziyoloji ve Reanimasyon AD .... more ... Mustafa Kemal Üniversitesi Tayfur Ata Sökmen Tıp Fakültesi Anesteziyoloji ve Reanimasyon AD ... B.Çağla Özbakış Akkurt, Kerem İnanoğlu, Olgun Karazincir, Alper Kararmaz, Selim ... ve hatta supin pozisyonlarda oluşabilen sonucunda morbidite ve mortalitesi yüksek olan bir ...
firattipdergisi.com
ÖZET Amaç: Çalışmamızda levobupivakaine eklenen fentanil ile elde edilen hipobarik solüsyon ile y... more ÖZET Amaç: Çalışmamızda levobupivakaine eklenen fentanil ile elde edilen hipobarik solüsyon ile yapılan spinal anestezinin farklı hasta pozisyonlarında blok karakteristikleri üzerine ve hemodinamik parametreler üzerine olan etkisini araştırmayı amaçladık. Gereç ve Yöntem: Elektif şartlarda artroskopik girişim planlanan ASA I-II grubu 40 hasta rastgele iki eşit gruba ayrıldı. Hastalara oturur pozisyonda, L 3-4 aralığından 25 Gouge spinal iğne ile girilerek 1.5 ml (7.5 mg) %0.5 levobupivakain ve 0.5 ml (25µ) fentanil verilerek spinal anestezi uygulandı. GRUP I'deki hastalara uygulama sonrası hemen sırt üstü pozisyon verilirken, GRUP II'deki hastalar 45º oturur pozisyona alındı. Duyusal blok seviyesi pinpirik testi ile, motor blok seviyesi ise Bromage skalası ile ilk 15 dk.her 2.5 dk'da, sonraki 15 dk her 5 dk'da bir ve 1.,2.,3.,4. saatlerde değerlendirildi ve kaydedildi. Bulgular: Demografik veriler ve hemodinamik parametreler açısından iki grup arasında anlamlı bir fark yoktu (p> 0.05). Duyusal blok seviyesi, motor blok seviyesi, maksimum duyu bloğu seviyesi ve oluşma zamanı, iki segment regresyon zamanı ve S1 segmente gerileme zamanı iki grup arasında karşılaştırıldığında istatistiksel olarak anlamlı fark saptanmadı (p>0.05). Sonuç: Hipobarik levobupivakain+ fentanil karışımı ile yapılan spinal anestezide supin ve 45 derece oturur pozisyonların, hemodinamik parametreler ile duyusal ve motor blok düzeyleri üzerine anlamlı bir fark oluşturacak düzeyde etki etmediği sonucuna vardık.