Amal Alzhrani - Independent Researcher (original) (raw)

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Papers by Amal Alzhrani

Research paper thumbnail of Effect of biosynthesized silver nanoparticles by Garcinia mangostana extract against human breast cancer cell line MCF-7

Food Science and Technology

Breast cancer is the greatest common malignancy in females. This syndrome represents a serious pu... more Breast cancer is the greatest common malignancy in females. This syndrome represents a serious public health problem that needs additional study to define its prediction and specific treatment. MCF-7 is a usually used breast cancer cell line that has been spread for many years by multiple groups. It shows to be a suitable model cell line for breast cancer studies worldwide, including those concerning anticancer. Anticancer and anti-inflammatory influences are important to treat the threats of chronic inflammation related with chronic diseases. Natural products have made and are remaining to make vital influences to the search for new anticancer agents. The use of natural foodstuffs in relationship with green nanoparticles has drawn attention because of its easy and eco-friendly protocol. Therefore, we aimed to investigate the antiproliferative activity of silver nanoparticles biosynthesized by mangosteen peel extract (MPE) on human breast cancer cell line (MCF-7) using [3-(4, 5-dimethylthiazolyl)-2, 5-diphenyl-tetrazolium bromide (MTT) method. In the present study serial concentrations (5, 10, 15, 50, 70, µg/mL) of cells biosynthesized silver nanoparticles by (MPE) was tested against MCF-7 cell lines showed a cytotoxic effects, morphological degeneration, damaging and has more effectiveness against breast cancer cells. The results showed a substantial a high reducing power, a sensible antiproliferative role and antioxidant activity. The results showed that silver nanoparticles biosynthesized by mangosteen peel extract (MPE) can be regarded as a suitable candidate for designing anticancer pharmaceutical preparations.

Research paper thumbnail of Assessment of End-User Susceptibility to Cybersecurity Threats in Saudi Arabia by Simulating Phishing Attacks

Information

Phishing attacks are cybersecurity threats that have become increasingly sophisticated. Phishing ... more Phishing attacks are cybersecurity threats that have become increasingly sophisticated. Phishing is a cyberattack that can be carried out using various approaches and techniques. Usually, an attacker uses trickery as well as fraudulent and disguised means to steal valuable personal information or to deceive the victim into running malicious code, thereby gaining access and controlling the victim’s systems. This study focuses on evaluating the level of cybersecurity knowledge and cyber awareness in Saudi Arabia. It is aimed at assessing end-user susceptibility through three phishing attack simulations. Furthermore, we elaborate on some of the concepts related to phishing attacks and review the steps required to launch such attacks. Subsequently, we briefly discuss the tools and techniques associated with each attack simulation. Finally, a comprehensive analysis is conducted to assess and evaluate the results.

Research paper thumbnail of Effect of biosynthesized silver nanoparticles by Garcinia mangostana extract against human breast cancer cell line MCF-7

Food Science and Technology

Breast cancer is the greatest common malignancy in females. This syndrome represents a serious pu... more Breast cancer is the greatest common malignancy in females. This syndrome represents a serious public health problem that needs additional study to define its prediction and specific treatment. MCF-7 is a usually used breast cancer cell line that has been spread for many years by multiple groups. It shows to be a suitable model cell line for breast cancer studies worldwide, including those concerning anticancer. Anticancer and anti-inflammatory influences are important to treat the threats of chronic inflammation related with chronic diseases. Natural products have made and are remaining to make vital influences to the search for new anticancer agents. The use of natural foodstuffs in relationship with green nanoparticles has drawn attention because of its easy and eco-friendly protocol. Therefore, we aimed to investigate the antiproliferative activity of silver nanoparticles biosynthesized by mangosteen peel extract (MPE) on human breast cancer cell line (MCF-7) using [3-(4, 5-dimethylthiazolyl)-2, 5-diphenyl-tetrazolium bromide (MTT) method. In the present study serial concentrations (5, 10, 15, 50, 70, µg/mL) of cells biosynthesized silver nanoparticles by (MPE) was tested against MCF-7 cell lines showed a cytotoxic effects, morphological degeneration, damaging and has more effectiveness against breast cancer cells. The results showed a substantial a high reducing power, a sensible antiproliferative role and antioxidant activity. The results showed that silver nanoparticles biosynthesized by mangosteen peel extract (MPE) can be regarded as a suitable candidate for designing anticancer pharmaceutical preparations.

Research paper thumbnail of Assessment of End-User Susceptibility to Cybersecurity Threats in Saudi Arabia by Simulating Phishing Attacks

Information

Phishing attacks are cybersecurity threats that have become increasingly sophisticated. Phishing ... more Phishing attacks are cybersecurity threats that have become increasingly sophisticated. Phishing is a cyberattack that can be carried out using various approaches and techniques. Usually, an attacker uses trickery as well as fraudulent and disguised means to steal valuable personal information or to deceive the victim into running malicious code, thereby gaining access and controlling the victim’s systems. This study focuses on evaluating the level of cybersecurity knowledge and cyber awareness in Saudi Arabia. It is aimed at assessing end-user susceptibility through three phishing attack simulations. Furthermore, we elaborate on some of the concepts related to phishing attacks and review the steps required to launch such attacks. Subsequently, we briefly discuss the tools and techniques associated with each attack simulation. Finally, a comprehensive analysis is conducted to assess and evaluate the results.

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