Amgad Gerges - Academia.edu (original) (raw)

Papers by Amgad Gerges

Research paper thumbnail of Оптимизация состава смесевых биотоплив на основе растительных масел для дизельных двигателей

Vestnik Volgogradskogo gosudarstvennogo universiteta. Serija 10. Innovatcionnaia deiatel’nost’, 2014

Кандидат технических наук, преподаватель кафедры «Английский язык для машиностроительных специаль... more Кандидат технических наук, преподаватель кафедры «Английский язык для машиностроительных специальностей», Московский государственный технический университет им. Н. Э. Баумана (МГТУ им. Н. Э. Баумана

Research paper thumbnail of Serum Neuron-Specific Enolase, Carnosinase, and Their Ratio in Acute Stroke

Stroke, 1996

Background and Purpose Few admission variables adequately predict neuronal damage and prognosis i... more Background and Purpose Few admission variables adequately predict neuronal damage and prognosis in individual patients after stroke. Therefore, there is a need for a reliable noninvasive surrogate measure of clinical outcome. Methods We have developed a surrogate measure of stroke outcome using the ratio of serum neuron-specific enolase (NSE) to human serum carnosinase (HSC) in 124 patients with acute ischemic or hemorrhagic stroke and 61 matched control subjects. Serum NSE is known to rise and HSC to fall after neuronal injury such as cerebral ischemia. Results Serum NSE levels were significantly higher and HSC levels lower in the patient group. The NSE/HSC ratio was elevated in patients with stroke: median (semiquartile) hemorrhages, 0.072 (0.033); infarcts, 0.039 (0.026); and control subjects, 0.019 (0.014), P =.0001. Patients with a primary intracerebral hemorrhage had nonsignificantly higher ratios than those with an infarct ( P =.082). The NSE/HSC ratio was significantly assoc...

Research paper thumbnail of Standardized Injection Technique and Regimen Minimizes Complication and Ensures Safety of N-Butyl-2Cyanoacrylate Injection for the Treatment of Gastric Fundal Varices

Gastrointestinal Endoscopy, Apr 1, 2005

N-butyl-2-cyanoacrylate has been successfully used for the treatment of bleeding from gastric fun... more N-butyl-2-cyanoacrylate has been successfully used for the treatment of bleeding from gastric fundal varices (FV). However, significant rebleeding rates and serious complications including embolism have been reported. Our purpose was to analyze the safety and efficacy of N-butyl-2-cyanoacrylate for FV bleeding by using a standardized injection technique and regimen. Retrospective. Two tertiary referral centers. A total of 131 patients (91 men/40 women) with FV underwent obliteration with N-butyl-2-cyanoacrylate by a standardized technique and regimen. (1) Dilution of 0.5 mL of N-butyl-2-cyanoacrylate with 0.8 mL of Lipiodol, (2) limiting the volume of mixture to 1.0 mL per injection to minimize the risk of embolism, (3) repeating intravariceal injections of 1.0 mL each until hemostasis was achieved, (4) obliteration of all tributaries of the FV, (5) repeat endoscopy 4 days after the initial treatment to confirm complete obliteration of all visible varices and repeat N-butyl-2-cyanoacrylate injection if necessary to accomplish complete obliteration. Immediate hemostasis rate, early rebleeding rate, bleeding-related mortality rate, procedure-related complications, long-term cumulative rebleeding-free rate, and cumulative survival rate. Initial hemostasis and variceal obliteration were achieved in all patients. The mean number of sessions was 1 (range 1-3). The mean total volume of glue mixture used was 4.0 mL (range 1-13 mL). There was no occurrence of early FV rebleeding, procedure-related complications, or bleeding-related death. The cumulative rebleeding-free rate at 1, 3, and 5 years was 94.5%, 89.3%, and 82.9%, respectively. Obliteration of bleeding FV with N-butyl-2-cyanoacrylate is safe and effective with use of a standardized injection technique and regimen.

Research paper thumbnail of Serum Neuron-Specific Enolase, Carnosinase, and Their Ratio in Acute Stroke: An Enzymatic Test for Predicting Outcome?

Stroke, 1996

Background and Purpose Few admission variables adequately predict neuronal damage and prognosis i... more Background and Purpose Few admission variables adequately predict neuronal damage and prognosis in individual patients after stroke. Therefore, there is a need for a reliable noninvasive surrogate measure of clinical outcome. Methods We have developed a surrogate measure of stroke outcome using the ratio of serum neuron-specific enolase (NSE) to human serum carnosinase (HSC) in 124 patients with acute ischemic or hemorrhagic stroke and 61 matched control subjects. Serum NSE is known to rise and HSC to fall after neuronal injury such as cerebral ischemia. Results Serum NSE levels were significantly higher and HSC levels lower in the patient group. The NSE/HSC ratio was elevated in patients with stroke: median (semiquartile) hemorrhages, 0.072 (0.033); infarcts, 0.039 (0.026); and control subjects, 0.019 (0.014), P =.0001. Patients with a primary intracerebral hemorrhage had nonsignificantly higher ratios than those with an infarct ( P =.082). The NSE/HSC ratio was significantly assoc...

Research paper thumbnail of Оптимизация состава смесевых биотоплив на основе растительных масел для дизельных двигателей

Vestnik Volgogradskogo gosudarstvennogo universiteta. Serija 10. Innovatcionnaia deiatel’nost’, 2014

Кандидат технических наук, преподаватель кафедры «Английский язык для машиностроительных специаль... more Кандидат технических наук, преподаватель кафедры «Английский язык для машиностроительных специальностей», Московский государственный технический университет им. Н. Э. Баумана (МГТУ им. Н. Э. Баумана

Research paper thumbnail of Serum Neuron-Specific Enolase, Carnosinase, and Their Ratio in Acute Stroke

Stroke, 1996

Background and Purpose Few admission variables adequately predict neuronal damage and prognosis i... more Background and Purpose Few admission variables adequately predict neuronal damage and prognosis in individual patients after stroke. Therefore, there is a need for a reliable noninvasive surrogate measure of clinical outcome. Methods We have developed a surrogate measure of stroke outcome using the ratio of serum neuron-specific enolase (NSE) to human serum carnosinase (HSC) in 124 patients with acute ischemic or hemorrhagic stroke and 61 matched control subjects. Serum NSE is known to rise and HSC to fall after neuronal injury such as cerebral ischemia. Results Serum NSE levels were significantly higher and HSC levels lower in the patient group. The NSE/HSC ratio was elevated in patients with stroke: median (semiquartile) hemorrhages, 0.072 (0.033); infarcts, 0.039 (0.026); and control subjects, 0.019 (0.014), P =.0001. Patients with a primary intracerebral hemorrhage had nonsignificantly higher ratios than those with an infarct ( P =.082). The NSE/HSC ratio was significantly assoc...

Research paper thumbnail of Standardized Injection Technique and Regimen Minimizes Complication and Ensures Safety of N-Butyl-2Cyanoacrylate Injection for the Treatment of Gastric Fundal Varices

Gastrointestinal Endoscopy, Apr 1, 2005

N-butyl-2-cyanoacrylate has been successfully used for the treatment of bleeding from gastric fun... more N-butyl-2-cyanoacrylate has been successfully used for the treatment of bleeding from gastric fundal varices (FV). However, significant rebleeding rates and serious complications including embolism have been reported. Our purpose was to analyze the safety and efficacy of N-butyl-2-cyanoacrylate for FV bleeding by using a standardized injection technique and regimen. Retrospective. Two tertiary referral centers. A total of 131 patients (91 men/40 women) with FV underwent obliteration with N-butyl-2-cyanoacrylate by a standardized technique and regimen. (1) Dilution of 0.5 mL of N-butyl-2-cyanoacrylate with 0.8 mL of Lipiodol, (2) limiting the volume of mixture to 1.0 mL per injection to minimize the risk of embolism, (3) repeating intravariceal injections of 1.0 mL each until hemostasis was achieved, (4) obliteration of all tributaries of the FV, (5) repeat endoscopy 4 days after the initial treatment to confirm complete obliteration of all visible varices and repeat N-butyl-2-cyanoacrylate injection if necessary to accomplish complete obliteration. Immediate hemostasis rate, early rebleeding rate, bleeding-related mortality rate, procedure-related complications, long-term cumulative rebleeding-free rate, and cumulative survival rate. Initial hemostasis and variceal obliteration were achieved in all patients. The mean number of sessions was 1 (range 1-3). The mean total volume of glue mixture used was 4.0 mL (range 1-13 mL). There was no occurrence of early FV rebleeding, procedure-related complications, or bleeding-related death. The cumulative rebleeding-free rate at 1, 3, and 5 years was 94.5%, 89.3%, and 82.9%, respectively. Obliteration of bleeding FV with N-butyl-2-cyanoacrylate is safe and effective with use of a standardized injection technique and regimen.

Research paper thumbnail of Serum Neuron-Specific Enolase, Carnosinase, and Their Ratio in Acute Stroke: An Enzymatic Test for Predicting Outcome?

Stroke, 1996

Background and Purpose Few admission variables adequately predict neuronal damage and prognosis i... more Background and Purpose Few admission variables adequately predict neuronal damage and prognosis in individual patients after stroke. Therefore, there is a need for a reliable noninvasive surrogate measure of clinical outcome. Methods We have developed a surrogate measure of stroke outcome using the ratio of serum neuron-specific enolase (NSE) to human serum carnosinase (HSC) in 124 patients with acute ischemic or hemorrhagic stroke and 61 matched control subjects. Serum NSE is known to rise and HSC to fall after neuronal injury such as cerebral ischemia. Results Serum NSE levels were significantly higher and HSC levels lower in the patient group. The NSE/HSC ratio was elevated in patients with stroke: median (semiquartile) hemorrhages, 0.072 (0.033); infarcts, 0.039 (0.026); and control subjects, 0.019 (0.014), P =.0001. Patients with a primary intracerebral hemorrhage had nonsignificantly higher ratios than those with an infarct ( P =.082). The NSE/HSC ratio was significantly assoc...