Amir Saleem - Academia.edu (original) (raw)

Papers by Amir Saleem

Comparative Study of Forest Cover and Carbon Stock Concerning Climate Change; a Case Study of Margalla Hills National Park, Islamabad, Pakistan

PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY

In the global carbon reserves, the forest is one of the central reserves. Humans face critical ch... more In the global carbon reserves, the forest is one of the central reserves. Humans face critical challenges with the intensification of ozone gases in the atmosphere. The study conducted in Margalla Hills National Park (MHNP), Islamabad capital territory, has analyzed environmental changes and carbon stock estimation. This area has multiple species types: Acacia Modesta, Quercus incana, Pinus roxburghii, Dodonaea viscosa, Olea ferruginea, Ziziphus mauritiana, etc. Remote sensing (RS) and Geographic Information System (GIS) technology were used to illustrate Land use land cover (LULC), Contour, Slope, Aspect, and total Rainfall calculation. LULC data of different years from 1997 to 2019 for every five years were analyzed. The analysis results showed that in Margalla Hills National Park, during the year 1997, total settlements were on about 145 hectares. Dense forest had an area of about 7262 ha, rocks were on about 5920 ha, barren land was about 2680 ha, and water bodies on about 38 ha...

The Iraqi Journal of Veterinary Medicine, 2022

The activity of a single subcutaneous injection of ivermectin at dose of 200 mcg/kg of body weigh... more The activity of a single subcutaneous injection of ivermectin at dose of 200 mcg/kg of body weight was evaluated against naturally acquired gastro-intestinal parasites in mules. Faecal samples were examined at the time of treatment and weekly thereafter up to 4 weeks. Results indicated that invrmectin was highly effective (100%) against Oxyuries equi, Strongyloides westeri, Tristostronglus axei, Trichhonema spp., and Strongylus spp. as judged one week after ivermectin administration. Complete elimination of Parascaris equorum eggs occurred two weeks after treatment. In contrast, ivermectin was not effective against the tape worms, Anoplocephala spp.. Infected animals had low levels of haemoglobin and red blood cells counts and an elevated packed cell volume, white blood cells and erythrocyte sedimentation rate. These values returned to normal values 21 days post treatment. No adverse reaction was recorded in the treated animals.

Limited and scarce feed and fodder availability has been considered as the major problem in harne... more Limited and scarce feed and fodder availability has been considered as the major problem in harnessing the potential of the livestock sector in Pakistan. With the objective to find out the suitable oat genotypes for providing higher fresh fodder yield, a field experiment was conducted during rabi season of 2014-15 at Agriculture Research Institute Tarnab, Peshawar Pakistan. The treatments consisted of thirteen genotypes of oat (NARC Oat(check), F-411, Kalash, Sargoda-1, Domount, Sargoda Oat-2011, No-632, Nz-0034, No-663, Canadian, Ck-1, 07-Cot-008 and Apsi-1). The results showed that the genotype “Kalash” produced the highest number of tillers (523 m ), fodder yield (75.6 t ha ) followed by No-663 2 1 (61.5 t ha ). The dry matter yield was higher for genotype “No-663” and “Kalash” (12.8, 12.3 t ha 1 1 respectively) compared to other genotypes. Check variety NARC Oat recorded highest Dry matter percentage (23). Growth parameters such as leaf area, leaf area index were superior for va...

Journal of entomology and zoology studies, 2017

The present study was conducted to know the commonest age group, vaccination status, nutritional ... more The present study was conducted to know the commonest age group, vaccination status, nutritional status and main complications in children admitted with measlesin 14 different union councils of district Karak from 25-Feb-17 to 22-May-17. In this descriptive study, 170 patients (6months to 9 years of age), with clinical diagnosis of Measles i.e. high grade fever, maculopapular rash, coryza, cough and conjunctivitis with its complications were included. Immunization status of the patients was checked by examining the EPI card where available or parental inquiry if EPIcard was not available. Out of these 170 patients only 74(43.6%) were positive with measles in which males were 41(55.4%) and 33(44.6%) were females. Maximum number of children who had measles was between 6 months to 3 years of age, followed by 3-4 years. 12 children were under one year of age, and 34 children were between 1-3 years of age. Only 25 children were between 4-6 years of age and 3 children’s were between 7-9 y...

Inkjet-Printed Colorimetric Paper-Based Gas Sensor Arrays for the Discrimination of Volatile Primary Amines with Amine-Responsive Dye-Encapsulating Polymer Nanoparticles

Biomimetic Sensing, 2019

Arrays of gas sensors are of high interest for "electronic nose" applications. Here, we... more Arrays of gas sensors are of high interest for "electronic nose" applications. Here, we describe the fabrication of a colorimetric single-use gas sensor array made of paper allowing the discrimination of volatile primary amines based on their polarity. For this purpose, polymeric nanoparticles with different polarities containing an amine-sensitive chromogenic dye are deposited onto paper substrates by means of inkjet printing. Data processing is conducted by red-green-blue (RGB) color extraction, followed by principal component analysis (PCA) or agglomerative hierarchical clustering (AHC) analysis. The application to the discrimination of two cheese samples is demonstrated.

Pure and Applied Biology, 2018

Current wheat improvement programs focuses on development of new high yielding, disease resistant... more Current wheat improvement programs focuses on development of new high yielding, disease resistant, stable and climatic resilient genotypes. Late planting is one of the major abiotic stresses, seriously influencing wheat production. In the current study, twenty seven bread wheat genotypes along with one check cultivar (Pirsabak-2008) were evaluated independently under normal (optimal) and late (stress) planting conditions at Cereal Crops Research Institute (CCRI), Pirsabak Nowshera Khyber Pakhtunkhwa Pakistan during 2013-14. Analysis of variance revealed highly significant (P < 0.01) differences among the genotypes, sowing dates and genotype × sowing dates interactions effects for the studied traits. Generally, reduction in plant height (0.41 to 10.91%) and grain yield (0.36 to 53.35%) was observed among the tested genotypes under late planting as compared to normal (optimal) planting. Least % reduction in grain yield was recorded for genotypes BWL-23 (0.36%), BWL-4(0.76%) and BWL-16 (1.22%) as compared to check (Pirsabak-2008). Eight stress selection indices i.e. Mean Productivity (MP), Tolerance (TOL), Geometric Mean Productivity (GMP), Harmonic mean (HM), Stress Selection Indices (SSI), Stress Tolerance Index (STI), Yield Index (YI) and Yield Stability Index (YSI) were determined for each genotype. Correlation analysis revealed that plant height and grain yield under both the planting conditions, had significant positive correlation with stress selection indices i.e. GM, HM, SSI and YI. These selection indices could be effective in identification of genotypes to late planting. Based on MP, GMP, HM, STI and YI genotypes i.e. Pirsabak-2008, BWL-23 and BWL-27 were found late planting stress tolerant and could be sown in both normal and late planting conditions.

Pakistan Journal of Phytopathology, 2017

Brassica napus (Rapeseed) affected by white rust is a major threat in Pakistan causing 60-90% yie... more Brassica napus (Rapeseed) affected by white rust is a major threat in Pakistan causing 60-90% yield losses. Two susceptible varieties of Brassica napus DGL and Oscar were sown in research area of department of Plant Pathology during 2016-17. Eight commercial fungicides were applied to check their efficacy to manage the white rust disease. Two concentrations (0.25% and 0.50%) of each fungicide were applied on weekly interval with hand sprayer separately on each variety. It was concluded that among all fungicides, Swing 72% (Metalaxyl 8% +Mancozeb 64%) was found most effective in reducing the disease incidence. It reduced the disease incidence effectively upto 24.09% followed by Antracol (Propineb 70%) 34.7%.

Pure and Applied Biology, 2017

To feed ever growing world population, development of high yielding and disease resistant wheat v... more To feed ever growing world population, development of high yielding and disease resistant wheat varieties are of utmost importance. A set of 20 genotypes including 18 facultative winter wheat lines and two checks (Pirsabak-2005 & Pirsabak-2013) cultivar were evaluated at Cereal Crops Research Institute (CCRI), Pirsabak Nowshera Khyber Pakhtunkhwa-Pakistan during 2014-15 cropping season. Highly significant differences (P ≤ 0.01) were found among the facultative lines for all traits except biological yield. Days to heading, maturity, plant height, biological yield, grain yield and harvest index varied from 116 to 133 days, 152 to 168 days and 87 to 128 cm, 11805.56 to 16666.67 kg ha -1 , 1627.78 to 4713.89 kg ha -1 and 15.11 to 36.00% respectively. Based on mean performance, FWWL-6 was found best for days to heading and maturity as it headed and matured earlier than other lines. For reduced height, FWWL-7 was found best. Comparison of mean for grain yield showed that FWWL-14 produced the highest grain yield (4713.89 kg ha -1 ) as compared to other genotypes. Heritability estimates in broad sense for days to heading, maturity, plant height, grain yield, biological yield and harvest index was 0.81, 0.59, 0.86, 0.26, 0.70 and 0.83 respectively. Genetic advance (%) for days to heading, days to maturity, plant height, biological yield, grain yield and harvest index was 3. 69, 2.61, 10.98, 4.83, 19.67 and 22.93 respectively. High heritability estimates for all the traits except biological yield, suggested that selection would be more effective to develop superior lines that could be used in future wheat improvement programs.

Studies of sheep experimentally poisoned with Hypericum perforatum

Veterinary and human toxicology, 1993

Sheep given different dosages and frequencies of Hypericum perforatum had decreased hemoglobin, r... more Sheep given different dosages and frequencies of Hypericum perforatum had decreased hemoglobin, red blood cell count, packed cell volumes, total protein, glucose, cholesterol, triglycerides, and serum alkaline phosphotase activities. Blood urea nitrogen, sodium, potassium, bilrubin (total and direct), and the activities of aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase and gamma glutamyltransferase increased. Hemato-biochemical assays were useful diagnostic aids to determine the severity of this plant's toxic effects.

Open Journal of Forestry, 2014

Chilas forest sub division in Diamer district, of Gilgit-Baltistan is located at northern regions... more Chilas forest sub division in Diamer district, of Gilgit-Baltistan is located at northern regions of Pakistan. We estimated tree density, diameter, height and volume of the dominant tree species in four blocks (Thore, Chilas, Thak Niat and Gunar) of Chilas forest sub division. The tree density of deodar was maximum with average 26 tree•ha −1 and minimum was of Chalgoza 4 trees•ha −1. The maximum average height showed by the dominant species (Fir, Kail, Deodar, and Chilgoza) of the study area to be 20.40, 16.06, 12.24 and 12.12 m respectively. Moreover the average maximum volume attained by the Kail, Fir, Deodar and Chalgoza trees was 1.92, 1.57, 0.46 and 0.291 m 3 •tree −1 respectively. Regression analysis was carried out to determine the relationship between diameter (cm), height (m), tree density (trees•ha −1) and volume (m 3 •ha −1). The findings of the study will help the future scientific management of the forest for sustained yield. The study also provides information about the unexplored growing stock and structure of the forests. Additionally, this study will help to understand the patterns of tree species composition and diversity in the northern part of Pakistan with dry temperate climate.

Procedia Engineering, 2011

Considering the characteristic of composite component design, a knowledge-based system for the de... more Considering the characteristic of composite component design, a knowledge-based system for the design of aircraft composite component is developed. The system design adopts client/application/server (C/A/S) three-layer structure. The implementation method and theory of the knowledge-based system is introduced in detail. Firstly, the system architecture of the developed knowledge-based system is presented. Then, the system framework of the case design base is also described. Case design of a composite component includes question description and solving scheme of this component. By comparing the question description and calculating the similarity of the components, new case design can be obtained from the existed case design. This knowledge-base system is integrated with CATIA software. The process of data exchange between CATIA and knowledge-base system is presented. The 3D model of composite component created in knowledge-base system can be modified by parameter driving. By implementing the proposed knowledge-based system, the design efficiency of composite component can be increased.

Genetic determinants of warfarin dosing in the Han-Chinese population

Pharmacogenomics, 2009

Warfarin, a widely prescribed oral anticoagulant, is used for the prevention of thromboembolism. ... more Warfarin, a widely prescribed oral anticoagulant, is used for the prevention of thromboembolism. Polymorphisms in CYP2C9 and VKORC1 have been shown to be associated with warfarin dose requirements. However, it is likely that other genes could also affect warfarin dose. Aims: In this study, we aimed to identify additional genes influencing warfarin dosing in the Han-Chinese population. Materials & methods: In this study, we screened for SNPs in 13 genes (VKORC1, CYP2C9, CYP2C18, PROC, APOE, EPHX1, CALU, GGCX, ORM1, ORM2, factor II, factor VII and CYP4F2) and tested their associations with warfarin dosing with univariate and multiple regression analysis. Results: Polymorphisms in the VKORC1 gene have the strongest effects on warfarin dose, followed by CYP2C9*3. In addition, our results showed that CYP2C18, PROC and EPHX1 have small but significant associations with warfarin dose. In multiple regression analysis, PROC and EPHX1 explained 3% of the dose variation. The incorporation of t...

Lecture Notes in Engineering and …, 2011

AbstractThe objective of this study is to simulate and analyze the effect of residual stress on ... more AbstractThe objective of this study is to simulate and analyze the effect of residual stress on NC machining distortion. NC machining distortion theory is studied by analyzing the typical aircraft arc shaped workpiece. The causes which lead to machining distortion are ...

Journal of Microbial & Biochemical Technology, 2016

Microbial & Biochemical Technology J o u rn al of M ic ro b ia l & Bioc h e m ic a l Te chno lo g y

PLOS Genetics, Jun 10, 2010

Protein palmitoylation has emerged as an important mechanism for regulating protein trafficking, ... more Protein palmitoylation has emerged as an important mechanism for regulating protein trafficking, stability, and proteinprotein interactions; however, its relevance to disease processes is not clear. Using a genome-wide, phenotype driven Nethyl-N-nitrosourea-mediated mutagenesis screen, we identified mice with failure to thrive, shortened life span, skin and hair abnormalities including alopecia, severe osteoporosis, and systemic amyloidosis (both AA and AL amyloids depositions). Whole-genome homozygosity mapping with 295 SNP markers and fine mapping with an additional 50 SNPs localized the disease gene to chromosome 7 between 53.9 and 56.3 Mb. A nonsense mutation (c.1273A.T) was located in exon 12 of the Zdhhc13 gene (Zinc finger, DHHC domain containing 13), a gene coding for palmitoyl transferase. The mutation predicted a truncated protein (R425X), and real-time PCR showed markedly reduced Zdhhc13 mRNA. A second gene trap allele of Zdhhc13 has the same phenotypes, suggesting that this is a loss of function allele. This is the first report that palmitoyl transferase deficiency causes a severe phenotype, and it establishes a direct link between protein palmitoylation and regulation of diverse physiologic functions where its absence can result in profound disease pathology. This mouse model can be used to investigate mechanisms where improper palmitoylation leads to disease processes and to understand molecular mechanisms underlying human alopecia, osteoporosis, and amyloidosis and many other neurodegenerative diseases caused by protein misfolding and amyloidosis.

Mice with Alopecia, Osteoporosis, and Systemic Amyloidosis Due to Mutation in Zdhhc13, a Gene Coding for Palmitoyl Acyltransferase

PLoS Genetics, 2010