Amit Agrawal - Academia.edu (original) (raw)

Papers by Amit Agrawal

World journal of clinical cases, Jan 16, 2017

Platelet concentrates (PC) [platelet-rich plasma (PRP) and platelet-rich fibrin (PRF)] are freque... more Platelet concentrates (PC) [platelet-rich plasma (PRP) and platelet-rich fibrin (PRF)] are frequently used for surgical procedures in medical and dental fields, particularly in oral and maxillofacial surgery, plastic surgery and sports medicine. The objective of all these technologies is to extract all the elements from a blood sample that could be used to improve healing and promote tissue regeneration. Although leukocyte rich and leukocyte poor PRP's have their own place in literature, the importance of non-platelet components in a platelet concentrate remains a mystery. PC have come a long way since its first appearance in 1954 to the T-PRF, A-PRF and i-PRF introduced recently. These PC find varied applications successfully in periodontics and implant dentistry as well. However, the technique of preparation, standing time, transfer process, temperature of centrifuge, vibration, etc., are the various factors for the mixed results reported in the literature. Until the introduct...

Indian journal of dental research : official publication of Indian Society for Dental Research

Accurate assessment of bone dimensions around an implant could best be done by the 3D imaging usi... more Accurate assessment of bone dimensions around an implant could best be done by the 3D imaging using computed tomography (CT). As rightly pointed out by authors,[1] routine use of CT in dentistry is not accepted due to its cost, excessive radiation, and general practicality. However, cone beam CT (CBCT), which the authors have failed to mention in their list, is commonly used in recent years. Patient radiation dose is five times lower (29–477 μSv) than normal CT (approximately 2000 μSv), as the exposure time is approximately 18 s, i.e. one‐seventh the amount compared with the conventional medical CT.[2] Furthermore, the time required for image reconstruction takes approximately 1 min for CBCT.[3]

Journal of Indian Society of Periodontology

World journal of clinical cases, Jan 16, 2015

Gingival enlargement is one of the frequent features of gingival diseases. However due to their v... more Gingival enlargement is one of the frequent features of gingival diseases. However due to their varied presentations, the diagnosis of these entities becomes challenging for the clinician. They can be categorized based on their etiopathogenesis, location, size, extent, etc. Based on the existing knowledge and clinical experience, a differential diagnosis can be formulated. Subsequently, after detailed investigation, clinician makes a final diagnosis or diagnosis of exclusion. A perfect diagnosis is critically important, since the management of these lesions and prevention of their recurrence is completely dependent on it. Furthermore, in some cases where gingival enlargement could be the primary sign of potentially lethal systemic diseases, a correct diagnosis of these enlargements could prove life saving for the patient or at least initiate early treatment and improve the quality of life. The purpose of this review article is to highlight significant findings of different types of ...

Human biology is very much like that of many other animals. That is why results from animal exper... more Human biology is very much like that of many other animals. That is why results from animal experiments apply to people. Animal models have been used to evaluate the pathogenes is of periodontal diseases and various periodontal treatment modalities. However, animals are used more as a matter of tradition, not because animal research has proved particularly successful or better than other modes of experimentation. The claim that animals are necessary for biomedical research is unsupported by the scientific literature. One must avoid direct extrapolation of results of studies in laboratory animals to the human. However, the welfare of human being will always outweigh the welfare of non-human beings and the quest for knowledge must never be hindered by what may be interpreted as ignorance or sentimentalism. Scientists, that work on experimental animals should keep them well and treat them with respect. They should be deeply concerned about the rational and humane use of animals in rese...

Case: A 42-year-old female patient with generalized amlodip ine influenced gingival enlargement r... more Case: A 42-year-old female patient with generalized amlodip ine influenced gingival enlargement reported in private practice. Drug substitution was followed by through scaling and root planning in mult iple sittings. The patient showed remarkable imp rovement within a month and at the 3rd month follow-up visit, patients' gingiva seemed to be absolutely normal. Discussion: Duration of 3-4 months should always be kept between first examination and decision of surgical intervention. If the enlargement is not showing response to non -surgical management or patient is having difficulty in speech, mastication or esthetics then surgical management is a better choice. Conclusion: The recall visits should be kept at shorter intervals so that not only the patients oral hygiene and disease condition can be monitored closely.

Introduction: Myiasis is an infectious disease, caused by the invasion of vital or necrotic tissu... more Introduction: Myiasis is an infectious disease, caused by the invasion of vital or necrotic tissue by larval flies; that is common in animals and human skin. However, intra-oral myiasis seems to be an uncommon phenomenon, as the oral tissues are not permanently exposed to the external environment. Case report: This article presents a classic case of 12-year-old male child who was medically compromised. In total around 43 maggots were removed from maxillary anterior region. The hallmark finding of this case was the fast recovery in response to the treatment. Conclusion: In addition to conventional treatment methods, application of doxycycline paste was found to be very beneficial. However, the exact role of this medication in management of lesions infested with larvae needs to be evaluated in future research. Regular follow-up of such patients and detailed information and instructions to the patient’s caretaker is the key to prevent recurrence.

Background: Epulis fissuratum is essentially one of overgrowth of fibrous tissue from vestibular ... more Background: Epulis fissuratum is essentially one of overgrowth of fibrous tissue from vestibular mucosa, that most commonly develops when a full denture or partial denture flange begins to impinge/irritate on the tissues in this area. It must be surgically removed with scalpel, electrosurgery or lasers. As a component of the treatment, the denture must usually be re-made or substantially adjusted to prevent recurrence. Case report: A fold of fibrous tissue in the anterior left segment of maxillary alveolar ridge with its base in vestibule, in a 65-year-old male patient, was excised using a diode laser. Follow-up was done after 15-days and 1-month and a new complete denture was fabricated for the patient. Conclusion: Based on the results obtained, it can be concluded that, diode laser is an excellent tool for surgical excision of fibrous overgrowths. It also helps in clean field with good vision, less postoperative bleeding or discomfort. Early recovery is an added advantage, since t...

The International journal of periodontics & restorative dentistry, 2012

Cleft lips, alveoli, and palates are the most common congenital malformations of the head and nec... more Cleft lips, alveoli, and palates are the most common congenital malformations of the head and neck region, all of which often can be managed successfully when presented at a young age. It is a common belief that clefts in the alveolar ridge should be treated with the help of bone grafting materials. This could be the best option when the cleft is to be treated in early age, when the patient is still developing and has high regenerative potential. However, in adults, the literature supports the fact that bone grafting in alveolar clefts has a higher chance for failure. The present case report exemplifies a periodontal plastic surgical procedure involving a combination of connective tissue and free gingival grafting to restore the form and function of a cleft alveolar ridge in an adult patient.

Indian journal of dentistry, 2014

Hyperpigmentation of gingiva becomes more pronounced if it is associated with "gummy smile.&... more Hyperpigmentation of gingiva becomes more pronounced if it is associated with "gummy smile." Correction of gummy smile and depigmentation together are key to complete patient satisfaction. An 810 nm (1.5 W, pulsed) GaAlAs diode laser was used to achieve the desired results in a 22-year-old female patient. The 6-month follow-up results showed excellent color and contour of the gingiva. Mere depigmentation without correcting gummy smile may look cosmetically good but esthetically unacceptable. Diode laser was used as it is known to be an excellent tool as compared with other conventional surgical procedures in terms of patient and operator comfort.

Journal of Indian Society of Periodontology, 2013

Sturge-Weber syndrome (encephalotrigeminal angiomatosis) is a rather uncommon congenital conditio... more Sturge-Weber syndrome (encephalotrigeminal angiomatosis) is a rather uncommon congenital condition that is characterized by a combination of venous angioma of leptomeninges over the cerebral cortex and ipsilateral angiomatous lesions of the face and sometimes of the skull, jaws, and oral soft tissues. It is commonly referred to as Sturge-Weber syndrome after Sturge and Weber who first described this affliction in 1879. This article presents a case of Sturge-Weber syndrome associated with severe gingival enlargement, its management, and follow-up results. A 15-year-old male patient was referred to the Department of Periodontics, Government Dental College and Hospital, for severe gingival enlargement. A detailed dental and medical history, clinical examination, and investigations confirmed the diagnosis of Sturge-Weber syndrome. This report reveals a classic presentation of the syndrome with emphasis on its oral manifestations. Periodontal management included thorough scaling and root planing followed by periodontal flap surgery to treat the gingival enlargement. Histopathologic examination of the excisional biopsy specimen revealed features suggestive of fibrous gingival enlargement. Reevaluation of the patient after 2 years showed remarkable (90%) reduction of the gingival enlargement in the maxillary arch and complete diminution (100%) in the mandibular arch. However, a slight recurrence was noted in the maxillary right quadrant. Sturge-Weber syndrome is clinically important to the periodontist because of its associated gingival vascular features and their complicating manifestations. Periodic systemic and oral examinations are recommended to identify and prevent any complications from the cranial and oral lesions.

World journal of clinical cases, Jan 16, 2017

Platelet concentrates (PC) [platelet-rich plasma (PRP) and platelet-rich fibrin (PRF)] are freque... more Platelet concentrates (PC) [platelet-rich plasma (PRP) and platelet-rich fibrin (PRF)] are frequently used for surgical procedures in medical and dental fields, particularly in oral and maxillofacial surgery, plastic surgery and sports medicine. The objective of all these technologies is to extract all the elements from a blood sample that could be used to improve healing and promote tissue regeneration. Although leukocyte rich and leukocyte poor PRP's have their own place in literature, the importance of non-platelet components in a platelet concentrate remains a mystery. PC have come a long way since its first appearance in 1954 to the T-PRF, A-PRF and i-PRF introduced recently. These PC find varied applications successfully in periodontics and implant dentistry as well. However, the technique of preparation, standing time, transfer process, temperature of centrifuge, vibration, etc., are the various factors for the mixed results reported in the literature. Until the introduct...

Indian journal of dental research : official publication of Indian Society for Dental Research

Accurate assessment of bone dimensions around an implant could best be done by the 3D imaging usi... more Accurate assessment of bone dimensions around an implant could best be done by the 3D imaging using computed tomography (CT). As rightly pointed out by authors,[1] routine use of CT in dentistry is not accepted due to its cost, excessive radiation, and general practicality. However, cone beam CT (CBCT), which the authors have failed to mention in their list, is commonly used in recent years. Patient radiation dose is five times lower (29–477 μSv) than normal CT (approximately 2000 μSv), as the exposure time is approximately 18 s, i.e. one‐seventh the amount compared with the conventional medical CT.[2] Furthermore, the time required for image reconstruction takes approximately 1 min for CBCT.[3]

Journal of Indian Society of Periodontology

World journal of clinical cases, Jan 16, 2015

Gingival enlargement is one of the frequent features of gingival diseases. However due to their v... more Gingival enlargement is one of the frequent features of gingival diseases. However due to their varied presentations, the diagnosis of these entities becomes challenging for the clinician. They can be categorized based on their etiopathogenesis, location, size, extent, etc. Based on the existing knowledge and clinical experience, a differential diagnosis can be formulated. Subsequently, after detailed investigation, clinician makes a final diagnosis or diagnosis of exclusion. A perfect diagnosis is critically important, since the management of these lesions and prevention of their recurrence is completely dependent on it. Furthermore, in some cases where gingival enlargement could be the primary sign of potentially lethal systemic diseases, a correct diagnosis of these enlargements could prove life saving for the patient or at least initiate early treatment and improve the quality of life. The purpose of this review article is to highlight significant findings of different types of ...

Human biology is very much like that of many other animals. That is why results from animal exper... more Human biology is very much like that of many other animals. That is why results from animal experiments apply to people. Animal models have been used to evaluate the pathogenes is of periodontal diseases and various periodontal treatment modalities. However, animals are used more as a matter of tradition, not because animal research has proved particularly successful or better than other modes of experimentation. The claim that animals are necessary for biomedical research is unsupported by the scientific literature. One must avoid direct extrapolation of results of studies in laboratory animals to the human. However, the welfare of human being will always outweigh the welfare of non-human beings and the quest for knowledge must never be hindered by what may be interpreted as ignorance or sentimentalism. Scientists, that work on experimental animals should keep them well and treat them with respect. They should be deeply concerned about the rational and humane use of animals in rese...

Case: A 42-year-old female patient with generalized amlodip ine influenced gingival enlargement r... more Case: A 42-year-old female patient with generalized amlodip ine influenced gingival enlargement reported in private practice. Drug substitution was followed by through scaling and root planning in mult iple sittings. The patient showed remarkable imp rovement within a month and at the 3rd month follow-up visit, patients' gingiva seemed to be absolutely normal. Discussion: Duration of 3-4 months should always be kept between first examination and decision of surgical intervention. If the enlargement is not showing response to non -surgical management or patient is having difficulty in speech, mastication or esthetics then surgical management is a better choice. Conclusion: The recall visits should be kept at shorter intervals so that not only the patients oral hygiene and disease condition can be monitored closely.

Introduction: Myiasis is an infectious disease, caused by the invasion of vital or necrotic tissu... more Introduction: Myiasis is an infectious disease, caused by the invasion of vital or necrotic tissue by larval flies; that is common in animals and human skin. However, intra-oral myiasis seems to be an uncommon phenomenon, as the oral tissues are not permanently exposed to the external environment. Case report: This article presents a classic case of 12-year-old male child who was medically compromised. In total around 43 maggots were removed from maxillary anterior region. The hallmark finding of this case was the fast recovery in response to the treatment. Conclusion: In addition to conventional treatment methods, application of doxycycline paste was found to be very beneficial. However, the exact role of this medication in management of lesions infested with larvae needs to be evaluated in future research. Regular follow-up of such patients and detailed information and instructions to the patient’s caretaker is the key to prevent recurrence.

Background: Epulis fissuratum is essentially one of overgrowth of fibrous tissue from vestibular ... more Background: Epulis fissuratum is essentially one of overgrowth of fibrous tissue from vestibular mucosa, that most commonly develops when a full denture or partial denture flange begins to impinge/irritate on the tissues in this area. It must be surgically removed with scalpel, electrosurgery or lasers. As a component of the treatment, the denture must usually be re-made or substantially adjusted to prevent recurrence. Case report: A fold of fibrous tissue in the anterior left segment of maxillary alveolar ridge with its base in vestibule, in a 65-year-old male patient, was excised using a diode laser. Follow-up was done after 15-days and 1-month and a new complete denture was fabricated for the patient. Conclusion: Based on the results obtained, it can be concluded that, diode laser is an excellent tool for surgical excision of fibrous overgrowths. It also helps in clean field with good vision, less postoperative bleeding or discomfort. Early recovery is an added advantage, since t...

The International journal of periodontics & restorative dentistry, 2012

Cleft lips, alveoli, and palates are the most common congenital malformations of the head and nec... more Cleft lips, alveoli, and palates are the most common congenital malformations of the head and neck region, all of which often can be managed successfully when presented at a young age. It is a common belief that clefts in the alveolar ridge should be treated with the help of bone grafting materials. This could be the best option when the cleft is to be treated in early age, when the patient is still developing and has high regenerative potential. However, in adults, the literature supports the fact that bone grafting in alveolar clefts has a higher chance for failure. The present case report exemplifies a periodontal plastic surgical procedure involving a combination of connective tissue and free gingival grafting to restore the form and function of a cleft alveolar ridge in an adult patient.

Indian journal of dentistry, 2014

Hyperpigmentation of gingiva becomes more pronounced if it is associated with "gummy smile.&... more Hyperpigmentation of gingiva becomes more pronounced if it is associated with "gummy smile." Correction of gummy smile and depigmentation together are key to complete patient satisfaction. An 810 nm (1.5 W, pulsed) GaAlAs diode laser was used to achieve the desired results in a 22-year-old female patient. The 6-month follow-up results showed excellent color and contour of the gingiva. Mere depigmentation without correcting gummy smile may look cosmetically good but esthetically unacceptable. Diode laser was used as it is known to be an excellent tool as compared with other conventional surgical procedures in terms of patient and operator comfort.

Journal of Indian Society of Periodontology, 2013

Sturge-Weber syndrome (encephalotrigeminal angiomatosis) is a rather uncommon congenital conditio... more Sturge-Weber syndrome (encephalotrigeminal angiomatosis) is a rather uncommon congenital condition that is characterized by a combination of venous angioma of leptomeninges over the cerebral cortex and ipsilateral angiomatous lesions of the face and sometimes of the skull, jaws, and oral soft tissues. It is commonly referred to as Sturge-Weber syndrome after Sturge and Weber who first described this affliction in 1879. This article presents a case of Sturge-Weber syndrome associated with severe gingival enlargement, its management, and follow-up results. A 15-year-old male patient was referred to the Department of Periodontics, Government Dental College and Hospital, for severe gingival enlargement. A detailed dental and medical history, clinical examination, and investigations confirmed the diagnosis of Sturge-Weber syndrome. This report reveals a classic presentation of the syndrome with emphasis on its oral manifestations. Periodontal management included thorough scaling and root planing followed by periodontal flap surgery to treat the gingival enlargement. Histopathologic examination of the excisional biopsy specimen revealed features suggestive of fibrous gingival enlargement. Reevaluation of the patient after 2 years showed remarkable (90%) reduction of the gingival enlargement in the maxillary arch and complete diminution (100%) in the mandibular arch. However, a slight recurrence was noted in the maxillary right quadrant. Sturge-Weber syndrome is clinically important to the periodontist because of its associated gingival vascular features and their complicating manifestations. Periodic systemic and oral examinations are recommended to identify and prevent any complications from the cranial and oral lesions.