Ana Maria Goulart Azevedo Tozzi (original) (raw)

Papers by Ana Maria Goulart Azevedo Tozzi

Journal of the Brazilian Chemical Society, 2014

A phytochemical study of roots of Dahlstedtia glaziovii (Fabaceae) furnished a new dibenzoylmetha... more A phytochemical study of roots of Dahlstedtia glaziovii (Fabaceae) furnished a new dibenzoylmethane (glaziovione), along with eighteen known compounds. Their structures were determined through 1D and 2D nuclear magnetic resonance (NMR) (heteronuclear single quantum coherence, HSQC, and heteronuclear multiple bond correlation, HMBC) and high-resolution mass spectrometry (HRMS) spectral analyses. The antiproliferative activity was investigated for the crude extracts, the dibenzoylmethanes 2'-methoxy-8-(α-α-dimethylallyl)-furano-[4",5":3',4']dibenzoylmethane, 3,4-methylenedioxy-2'-methoxy-8-(α-α-dimethylallyl)-furano-[4",5":3',4']dibenzoylmethane and pongamol, and the flavones lanceolatin B, karanjin, pongapin and 3',4'-methylenedioxy-2'',2''-dimethylpyrano-[5'',6'':8,7]-flavone. The dibenzoylmethanes were more active than the flavones.The extracts were evaluated for their antimicrobial effects, but none was shown to be active.

Kew Bulletin, Mar 1, 2016

A taxonomic revision of Platycyamus, a South American genus, is presented. The genus has traditio... more A taxonomic revision of Platycyamus, a South American genus, is presented. The genus has traditionally comprised three taxa (two species, one with two varieties). All three are lectotypified in this study, but the infraspecific taxa P. regnellii var. glabrescens and P. regnellii var. regnellii are not recognised here as distinct. A key to distinguish P. regnellii from P. ulei is presented together with species descriptions and the first published line drawings of the two.

Systematic Botany, Oct 1, 2014

Phytotaxa, Nov 5, 2014

Deguelia decorticans, a new lianescent species of Leguminosae from the Brazilian Amazon, is here ... more Deguelia decorticans, a new lianescent species of Leguminosae from the Brazilian Amazon, is here described and illustrated. The new species has flowers which resemble those of Deguelia duckeana and Deguelia rariflora and it might be closely related to them, probably forming a species complex. However, this new species can be easily distinguished by some morphological and reproductive characteristics.

Novon, 2001

Myrocarpus emarginatus, known only from Bolivia, is described and illustrated. Its di¬ agnostic c... more Myrocarpus emarginatus, known only from Bolivia, is described and illustrated. Its di¬ agnostic characters are the emarginate leaflet apex, pellucid dots and streaks immersed on the leaflet blades, and the areolate reticulation of the seed chamber. The new species is morphologically sim¬ ilar to Myrocarpus fastigiatus Allemao, especially in the shape of its leaflets, ranging from elliptic to oblong; neither species exhibits leaflets with an acuminate apex.

Ecological Indicators, Feb 1, 2017

The South American corridor of seasonally dry vegetation (SACSV) includes different types of phys... more The South American corridor of seasonally dry vegetation (SACSV) includes different types of physiognomies forming a continuous corridor with high biodiversity and endemism; however, little attention has been paid to the conservation of the SACSV. As this is an area with great diversity, cataloguing all the species is challenging. Thus, we suggest the use of Leguminosae species (trees and shrubs) as bioindicators of the different types of vegetation present in the area and to identify priority areas for conservation of the SACSV, since the family is highly represented in this vegetation. The study area was divided into 358 grid cells with recorded specimens. For each grid cell, species richness, taxonomic diversity, number of species restricted to one type of vegetation, and threatened and indicator species of phytogeographic domain were calculated. To determine the phytogeographic domains and indicator species, analysis of similarity, cluster and indicator species (ISA) were performed. The results show that 43% of the grid cells (154) have high biological importance for conservation (high taxonomic diversity, species richness and number of restricted species), all of which lie outside of protected areas. We identified 72 indicator species for seven floristic units, which, in general, include areas of the same phytogeographic domain, supporting the existing classification systems. We suggest that for effective conservation of biodiversity present in the SACSV, it is necessary to establish protected areas throughout the SACSV.

Eclética Química, 2006

The chemical indexes, suggested by Gottlieb et al., have not been used before regarding evolution... more The chemical indexes, suggested by Gottlieb et al., have not been used before regarding evolutionary tendency of species in the Swartzia genus. However, the importance of this work encouraged for an analysis of the Swartzia genus using the metabolites isolated from nine species. The analysis, based on calculated chemical indexes, provided an evolutionary tendency for these plants, which correlates with the classification based on morphological analysis.

Systematic Botany, Jul 1, 2014

Phytotaxa, Jul 17, 2012

A new species of Mucuna from Costa Rica and Panama is described and illustrated. Mucuna monticola... more A new species of Mucuna from Costa Rica and Panama is described and illustrated. Mucuna monticola is mainly known from the highlands of the Cordilleras of Guanacaste, Tilarán, Central and Talamanca in Costa Rica, and in Panama in particular from the Chiriqui area. It is superficially similar to Mucuna mutisiana and M. killipiana, but it differs from both in multiple aspects of its morphology and is unique among Neotropical Mucuna in its pod, which is larger and longer with conspicuous irregular lamellae or reticulate-ridged, not constricted between the seeds.

Brazilian Journal of Botany, Dec 1, 1998

... sn (RB); Belo Horizonte, 4/1982 (fl.) ET Neto 61 (UEC); Paraná, Londrina, Bosque II, 9/1986 (... more ... sn (RB); Belo Horizonte, 4/1982 (fl.) ET Neto 61 (UEC); Paraná, Londrina, Bosque II, 9/1986 (fr.), MC Dias & CG Perri (FUEL 3125); Rio de Janeiro, Rio de Janeiro, 4/1942 (fl.), H. Almeida sn (R). 8. Machaerium lanceolatum (Vell.) JF Macbr., Field. Mus. Hist. Nat. ser. Bot. 13:281. ...

Plant Systematics and Evolution, Jul 4, 2014

A new genus Limadendron (Leguminosae, Papilionoideae, Brongniartieae) from northern South America... more A new genus Limadendron (Leguminosae, Papilionoideae, Brongniartieae) from northern South America is described and illustrated. The new genus is segregated from Poecilanthe based on a previous phylogenetic analysis. Limadendron is sister to Cyclolobium and differs from it mainly by its woody dehiscent legumes contrasting with the winged samaroid fruits of the latter. Two new combinations, Limadendron amazonicum (Ducke) Meireles & A. M. G. Azevedo and Limadendron hostmannii (Benth.) Meireles & A. M. G. Azevedo, are proposed. A distribution map and an identification key for the species are also provided.

Systematic Botany, Oct 1, 2014

Anais Da Academia Brasileira De Ciencias, Dec 1, 2004

The light petroleum extract from the roots of Lonchocarpus muehlbergianus Hassl contained nine fl... more The light petroleum extract from the roots of Lonchocarpus muehlbergianus Hassl contained nine flavonoids, including six new ones.

Phytochemistry, Dec 1, 1999

From the petroleum extract of Lonchocarpus atropurpureus Benth. roots, 5,2'-dihydroxy-3-methoxy-6... more From the petroleum extract of Lonchocarpus atropurpureus Benth. roots, 5,2'-dihydroxy-3-methoxy-6,7-(20,20dimethylchromene)-8-(30',30 '-dimethylallyl)-¯avanone and 2 ',3,5-trihydroxy-6,7-(20,20-dimethylchromene)-8-(30',30'-dimethylallyl)-¯avanone were isolated, together with three known¯avanoids and a mixture of two pentacyclic triterpenes. Their molecular structures were determined by spectral analyses (UV, IR, MS and 1D-and 2D-NMR experiments).

Anais Da Academia Brasileira De Ciencias, Sep 1, 2007

The analysis of root extracts from Lonchocarpus montanus A.M.G. Azevedo resulted in the isolation... more The analysis of root extracts from Lonchocarpus montanus A.M.G. Azevedo resulted in the isolation of twenty three compounds chiefly flavonoids of which five (four flavonoids and one benzophenone) are described for the first time. The molecular structures of the new compounds (1-5) were determined through spectral analysis (UV, IR, MS and NMR) as being: 2-hydroxy-8-(α,α-dimethylallyl)-2 , 2dimethylpyrano-(5 ,6 :3 ,4)-dibenzoylmethane (1), 2-methoxy-8-(α, α-dimethylallyl)-2 , 2-dimethylpyrano-(5 ,6 :3 ,4)-dibenzoylmethane (2), 4-methoxy-2 ,2-dimethylpyrano-(5 ,6 :8,7)-flavone (3), 2-(1-hydroxy-1-methylethyl)-furano-(4 ,5 :8,7)-flavone (4) and [2-methoxy-furano-(4 ,5 :3 ,4)-phenyl]phenylmethanone (5). Additionally, fifteen fatty acids were detected through GC-MS analysis of the corresponding methyl esters [(CH 3) 2 CH(CH 2) 8 COOH and CH 3 (CH 2) n COOH (n = 6, 12-24)]. Quantitative RP-HPLC showed that the most abundant flavonoids in the petroleum ether and dichloromethane extracts were pongamol (19%) and lanceolatine B (8.0%), respectively. In the bioautography assay, the extracts, pongamol (9), lanceolatine B (10), isolonchocarpin (14), derriobtusone A (17) and medicarpine (18) were active against Staphilococus aureus whereas 9 also against Bacillus subtilis and Cladosporium cladosporioides. Compound 1, 2 ,2-dimethylpyrano-(5 ,6 :8,7)-flavone (11) and furano-(12 ,13 :7,8)-4-methoxy flavone (12) were active against Fusarium oxysporium whereas 11 also against Rhizopus orizae. The extracts, compounds 9, 10, 17 and (E)-7-O-methoxypongamol (23) displayed high toxicity in the brine shrimp lethality assay.

Journal of the Brazilian Chemical Society, 2014

A phytochemical study of roots of Dahlstedtia glaziovii (Fabaceae) furnished a new dibenzoylmetha... more A phytochemical study of roots of Dahlstedtia glaziovii (Fabaceae) furnished a new dibenzoylmethane (glaziovione), along with eighteen known compounds. Their structures were determined through 1D and 2D nuclear magnetic resonance (NMR) (heteronuclear single quantum coherence, HSQC, and heteronuclear multiple bond correlation, HMBC) and high-resolution mass spectrometry (HRMS) spectral analyses. The antiproliferative activity was investigated for the crude extracts, the dibenzoylmethanes 2'-methoxy-8-(α-α-dimethylallyl)-furano-[4",5":3',4']dibenzoylmethane, 3,4-methylenedioxy-2'-methoxy-8-(α-α-dimethylallyl)-furano-[4",5":3',4']dibenzoylmethane and pongamol, and the flavones lanceolatin B, karanjin, pongapin and 3',4'-methylenedioxy-2'',2''-dimethylpyrano-[5'',6'':8,7]-flavone. The dibenzoylmethanes were more active than the flavones.The extracts were evaluated for their antimicrobial effects, but none was shown to be active.

Kew Bulletin, Mar 1, 2016

A taxonomic revision of Platycyamus, a South American genus, is presented. The genus has traditio... more A taxonomic revision of Platycyamus, a South American genus, is presented. The genus has traditionally comprised three taxa (two species, one with two varieties). All three are lectotypified in this study, but the infraspecific taxa P. regnellii var. glabrescens and P. regnellii var. regnellii are not recognised here as distinct. A key to distinguish P. regnellii from P. ulei is presented together with species descriptions and the first published line drawings of the two.

Systematic Botany, Oct 1, 2014

Phytotaxa, Nov 5, 2014

Deguelia decorticans, a new lianescent species of Leguminosae from the Brazilian Amazon, is here ... more Deguelia decorticans, a new lianescent species of Leguminosae from the Brazilian Amazon, is here described and illustrated. The new species has flowers which resemble those of Deguelia duckeana and Deguelia rariflora and it might be closely related to them, probably forming a species complex. However, this new species can be easily distinguished by some morphological and reproductive characteristics.

Novon, 2001

Myrocarpus emarginatus, known only from Bolivia, is described and illustrated. Its di¬ agnostic c... more Myrocarpus emarginatus, known only from Bolivia, is described and illustrated. Its di¬ agnostic characters are the emarginate leaflet apex, pellucid dots and streaks immersed on the leaflet blades, and the areolate reticulation of the seed chamber. The new species is morphologically sim¬ ilar to Myrocarpus fastigiatus Allemao, especially in the shape of its leaflets, ranging from elliptic to oblong; neither species exhibits leaflets with an acuminate apex.

Ecological Indicators, Feb 1, 2017

The South American corridor of seasonally dry vegetation (SACSV) includes different types of phys... more The South American corridor of seasonally dry vegetation (SACSV) includes different types of physiognomies forming a continuous corridor with high biodiversity and endemism; however, little attention has been paid to the conservation of the SACSV. As this is an area with great diversity, cataloguing all the species is challenging. Thus, we suggest the use of Leguminosae species (trees and shrubs) as bioindicators of the different types of vegetation present in the area and to identify priority areas for conservation of the SACSV, since the family is highly represented in this vegetation. The study area was divided into 358 grid cells with recorded specimens. For each grid cell, species richness, taxonomic diversity, number of species restricted to one type of vegetation, and threatened and indicator species of phytogeographic domain were calculated. To determine the phytogeographic domains and indicator species, analysis of similarity, cluster and indicator species (ISA) were performed. The results show that 43% of the grid cells (154) have high biological importance for conservation (high taxonomic diversity, species richness and number of restricted species), all of which lie outside of protected areas. We identified 72 indicator species for seven floristic units, which, in general, include areas of the same phytogeographic domain, supporting the existing classification systems. We suggest that for effective conservation of biodiversity present in the SACSV, it is necessary to establish protected areas throughout the SACSV.

Eclética Química, 2006

The chemical indexes, suggested by Gottlieb et al., have not been used before regarding evolution... more The chemical indexes, suggested by Gottlieb et al., have not been used before regarding evolutionary tendency of species in the Swartzia genus. However, the importance of this work encouraged for an analysis of the Swartzia genus using the metabolites isolated from nine species. The analysis, based on calculated chemical indexes, provided an evolutionary tendency for these plants, which correlates with the classification based on morphological analysis.

Systematic Botany, Jul 1, 2014

Phytotaxa, Jul 17, 2012

A new species of Mucuna from Costa Rica and Panama is described and illustrated. Mucuna monticola... more A new species of Mucuna from Costa Rica and Panama is described and illustrated. Mucuna monticola is mainly known from the highlands of the Cordilleras of Guanacaste, Tilarán, Central and Talamanca in Costa Rica, and in Panama in particular from the Chiriqui area. It is superficially similar to Mucuna mutisiana and M. killipiana, but it differs from both in multiple aspects of its morphology and is unique among Neotropical Mucuna in its pod, which is larger and longer with conspicuous irregular lamellae or reticulate-ridged, not constricted between the seeds.

Brazilian Journal of Botany, Dec 1, 1998

... sn (RB); Belo Horizonte, 4/1982 (fl.) ET Neto 61 (UEC); Paraná, Londrina, Bosque II, 9/1986 (... more ... sn (RB); Belo Horizonte, 4/1982 (fl.) ET Neto 61 (UEC); Paraná, Londrina, Bosque II, 9/1986 (fr.), MC Dias & CG Perri (FUEL 3125); Rio de Janeiro, Rio de Janeiro, 4/1942 (fl.), H. Almeida sn (R). 8. Machaerium lanceolatum (Vell.) JF Macbr., Field. Mus. Hist. Nat. ser. Bot. 13:281. ...

Plant Systematics and Evolution, Jul 4, 2014

A new genus Limadendron (Leguminosae, Papilionoideae, Brongniartieae) from northern South America... more A new genus Limadendron (Leguminosae, Papilionoideae, Brongniartieae) from northern South America is described and illustrated. The new genus is segregated from Poecilanthe based on a previous phylogenetic analysis. Limadendron is sister to Cyclolobium and differs from it mainly by its woody dehiscent legumes contrasting with the winged samaroid fruits of the latter. Two new combinations, Limadendron amazonicum (Ducke) Meireles & A. M. G. Azevedo and Limadendron hostmannii (Benth.) Meireles & A. M. G. Azevedo, are proposed. A distribution map and an identification key for the species are also provided.

Systematic Botany, Oct 1, 2014

Anais Da Academia Brasileira De Ciencias, Dec 1, 2004

The light petroleum extract from the roots of Lonchocarpus muehlbergianus Hassl contained nine fl... more The light petroleum extract from the roots of Lonchocarpus muehlbergianus Hassl contained nine flavonoids, including six new ones.

Phytochemistry, Dec 1, 1999

From the petroleum extract of Lonchocarpus atropurpureus Benth. roots, 5,2'-dihydroxy-3-methoxy-6... more From the petroleum extract of Lonchocarpus atropurpureus Benth. roots, 5,2'-dihydroxy-3-methoxy-6,7-(20,20dimethylchromene)-8-(30',30 '-dimethylallyl)-¯avanone and 2 ',3,5-trihydroxy-6,7-(20,20-dimethylchromene)-8-(30',30'-dimethylallyl)-¯avanone were isolated, together with three known¯avanoids and a mixture of two pentacyclic triterpenes. Their molecular structures were determined by spectral analyses (UV, IR, MS and 1D-and 2D-NMR experiments).

Anais Da Academia Brasileira De Ciencias, Sep 1, 2007

The analysis of root extracts from Lonchocarpus montanus A.M.G. Azevedo resulted in the isolation... more The analysis of root extracts from Lonchocarpus montanus A.M.G. Azevedo resulted in the isolation of twenty three compounds chiefly flavonoids of which five (four flavonoids and one benzophenone) are described for the first time. The molecular structures of the new compounds (1-5) were determined through spectral analysis (UV, IR, MS and NMR) as being: 2-hydroxy-8-(α,α-dimethylallyl)-2 , 2dimethylpyrano-(5 ,6 :3 ,4)-dibenzoylmethane (1), 2-methoxy-8-(α, α-dimethylallyl)-2 , 2-dimethylpyrano-(5 ,6 :3 ,4)-dibenzoylmethane (2), 4-methoxy-2 ,2-dimethylpyrano-(5 ,6 :8,7)-flavone (3), 2-(1-hydroxy-1-methylethyl)-furano-(4 ,5 :8,7)-flavone (4) and [2-methoxy-furano-(4 ,5 :3 ,4)-phenyl]phenylmethanone (5). Additionally, fifteen fatty acids were detected through GC-MS analysis of the corresponding methyl esters [(CH 3) 2 CH(CH 2) 8 COOH and CH 3 (CH 2) n COOH (n = 6, 12-24)]. Quantitative RP-HPLC showed that the most abundant flavonoids in the petroleum ether and dichloromethane extracts were pongamol (19%) and lanceolatine B (8.0%), respectively. In the bioautography assay, the extracts, pongamol (9), lanceolatine B (10), isolonchocarpin (14), derriobtusone A (17) and medicarpine (18) were active against Staphilococus aureus whereas 9 also against Bacillus subtilis and Cladosporium cladosporioides. Compound 1, 2 ,2-dimethylpyrano-(5 ,6 :8,7)-flavone (11) and furano-(12 ,13 :7,8)-4-methoxy flavone (12) were active against Fusarium oxysporium whereas 11 also against Rhizopus orizae. The extracts, compounds 9, 10, 17 and (E)-7-O-methoxypongamol (23) displayed high toxicity in the brine shrimp lethality assay.