Andrei KOZMA - Academia.edu (original) (raw)
Papers by Andrei KOZMA
BMJ, 1985
Neonatal screening for congenital hypothyroidism was introduced in the City of Birmingham in 1980... more Neonatal screening for congenital hypothyroidism was introduced in the City of Birmingham in 1980 by measuring concentrations of both thyroid stimulating hormone and thyroxine in plasma. Over two years 30108 babies were tested. Thirty one babies were recalled because of thyroid stimulating hormone concentrations greater than 40 mU/l, of whom 12 were treated with replacement thyroxine. Six babies were found to have low thyroxine concentrations because of reduced thyroxine binding globulin and five raised thyroxine values because of increased thyroxine binding globulin. As a result of this study screening was continued with measurement of thyroid stimulating hormone only as the primary test for congenital hypothyroidism, the thyroxine value being measured only when the concentration of thyroid stimulating hormone exceeded 20 mU/l.
Romanian Journal of Legal Medicine, 2019
Romanian Journal of Legal Medicine, 2019
Annals of the Academy of Romanian Scientists Series on Biological Sciences
In the context of the increased prevalence of dental caries and periodontal disease reported in o... more In the context of the increased prevalence of dental caries and periodontal disease reported in our country, the extensive partial edentation is a common pathology, which requires complex treatment solutions. Implant-prosthetic therapy is the optimal treatment solution from a biological, functional and biomechanical point of view. Interdisciplinary management of implant-prosthetic therapy frequently involves the reconstruction of alveolar ridges in the pro-implant stage. The specialists in implantology and dento-alveolar surgery face the issue of the selection of grafting materials and techniques in relation to systemic, loco-regional, local factors and the planned prosthetic solution. In this context, a practical guide for the use of grafting materials and techniques may be useful to practitioners in order to optimize the aesthetic and functional results in the implant-prosthetic therapy of edentulous patients.
Social Science Research Network, Aug 23, 2016
Romanian Journal of Oral Rehabilitation, 2019
Abstract. As dental caries is a common disease with high prevalence worldwide, many researches ar... more Abstract. As dental caries is a common disease with high prevalence worldwide, many researches are focused nowadays on the longevity of direct composite restorations and indirect restorations both in the anterior and posterior dental substance loss. The mean survival rates of the direct composite restorations, after follow-up period of 3-10 years, are between 85,10% and 97,40%. The mean survival rates of the indirect coronal restorations, after follow-up period of 8-10 years, are between 90,40% and 100%. In the recovery of the esthetic and masticatory functions affected by coronal substance loss, the direct composite restorations and ceramic inlays or onlays have advantages and limits. The dentists must focus on factors related to material and technique as well as on clinical and biological factors, when a repair versus replacement decision must be taken
Romanian Journal of Medical and Dental Education, 2019
To increase the effectiveness of the dental prevention and therapeutic politics, World Health Org... more To increase the effectiveness of the dental prevention and therapeutic politics, World Health Organisation has focused the projects regarding the dental health on health insurance systems, social environment, as well as on cultural factors. Cultural factors related to oral health include concepts regarding ethiological factors and dental treatment, race, geographic area, family habits and influence, gender factor, socioeconomic factors, nutritional factors, and cultural beliefs and taboos. Unfavourable anthropological factors are associated both with high prevalence of the edentation in Romania and difficulties to apply the most appropriate prosthetic solutions for the long term success. Romania has a close collaboration with WHO (project Oral Health Programme) to initiate programs, focused on various cultural and demographic factors, aiming to improve the oral health status
Annals of the Academy of Romanian Scientists Series on Biological Sciences
Digital expert systems, commonly used in medicine, can be implemented successfully in the analysi... more Digital expert systems, commonly used in medicine, can be implemented successfully in the analysis and planning of treatments in dentistry. In implant-prosthetic therapy, these software applications epresent necessary adjuvant tools in optimizing therapeutic decisions regarding the pro-implant and implant stages as well as in creating a therapeutic planning algorithm. PRODENT Acad Expert (data recording and database) and PRODENT Indices (calculation of biological indices and recommendation for the optimal treatment solution) (Neo-Tech, Romania) are tools that allows the registration and entry of data in the database, registration of clinical and biological indices in pretreatment and post-implant stage, respectively the recommendation of an optimal prosthetic solution. The use of this application is necessary in monitoring changes related to the biological components of the stomatognathic system in postimplant stage. Expert applications for the assessment of mucosal and bone support...
Romanian Journal of Medical and Dental Education, 2019
The active mastication has not only role in food intake and digestion, but also in the maintainin... more The active mastication has not only role in food intake and digestion, but also in the maintaining and promotion of the cognitive functions. It was demonstrated the increase of the blood supply in neuronal areas during mastication due to the stimulation of dental baroreceptors, alveolar baroreceptors and masticatory muscles during. Chewing was associated with greater alertness, more positive mood, faster reaction times, improved focus as well as with the improvement of the learning ability. On the other part, epidemiologic studies found that elderly individuals with high number of absent teeth are more likely to develop cognitive dysfunction, and neurodegenerative diseases like Alzheimer and dementia.
Romanian Journal of Medical and Dental Education, 2021
Contemporary human diet is a major cause of tooth decay and other systemic diseases, such as diab... more Contemporary human diet is a major cause of tooth decay and other systemic diseases, such as diabetes, obesity and cardiovascular disease. Since the quantitative relationship between food principles is an important prophylactic factor of health, qualitative research in the form of theoretical review of specialty literature and experimental case studies has been carried out, with the aim of highlighting the roles of food principles for the prophylaxis of oral lesions, tooth decay and general oral health. The conclusions converge to the unsurprising perspective that the lack of dietary principles, the lack of proteins, for example, during the development of dental enamel matrix, favors the appearance of caries, while an excess of lipids decrease their incidence. Exogenous prophylaxis through diet of tooth decay is achieved by eating foods with increased consistency, which have a mechanical brushing role. Diet must be balanced by dietary principles: low in refined sugars and rich in vi...
Romanian Journal of Medical Practice, 2019
Candidoza orală este o infecţie a cavităţii orale cauzată de către Candida albicans. Mai mulţi fa... more Candidoza orală este o infecţie a cavităţii orale cauzată de către Candida albicans. Mai mulţi factori pot contribui la dezvoltarea candidozei precum: utilizarea protezelor, inhalatoarelor de corticosteroizi, xerostomia, stări de imunosupresie (cum ar fi infecţia cu virusul imunodeficienţei umane (HIV), leucemie, malnutriţie, scăderea imunităţii secundară vârstei, disfuncţie endocrină, cum ar fi diabetul, chimioterapie sistemică, terapie cu radiaţii, utilizarea de corticosteroizi sistemici).
Romanian Journal of Medical and Dental Education, 2019
Intercalated edentations have high prevalence both in anterior and lateral prosthetic areas. Vari... more Intercalated edentations have high prevalence both in anterior and lateral prosthetic areas. Various prosthetic solutions can be proposed for these clinical situations, including fixed bridges, hybrid prosthesis, or implant-prosthetic rehabilitation. Financial reasons or abutment teeth affected by severe periodontal disease, can conduct to the replacement of these prosthetic solutions with removable dentures but the oral hygiene as well as the period of adaptation and restoration of functions are more difficult. Pro-prosthetic treatments, crown lengthening and surgery procedures (augmentation associated or not to guided bone regeneration technique) on the level of the alveolar ridge, must be considered to improve the biological and clinical indices of the prosthetic area. The decisional processes are dealing with a great number of variables which need beeing evaluated and correlated with clinical factors, technological solutions, financial costs and patients' demands.
Archives of the Balkan Medical Union, 2019
Caractéristiques psychologiques des maladies orales chez les personnes âgées
Revista Medicală Română, Dec 31, 2019
Melasma este o afecțiune cronică a pielii, caracterizată prin macule brune neregulate, distribuit... more Melasma este o afecțiune cronică a pielii, caracterizată prin macule brune neregulate, distribuite simetric pe zonele expuse la soare ale corpului, în special pe față. Deși în general reprezintă doar o problemă "cosmetică", melasma poate afecta semnificativ calitatea vieții pacienților. Patogenia sa nu este încă pe deplin înțeleasă, fiind propuși mai mulți factori posibil declanșatori. În continuare, vom aborda anumite aspecte ale melasmei, în funcție de cercetările actuale.
Anodontia is a rare genetic disorder, characterized by the partial or complete absence of dentiti... more Anodontia is a rare genetic disorder, characterized by the partial or complete absence of dentition. It is rarely found in an isolated form, most of the time being associated with genetic syndromes such as ectodermal dysplasia. Ectodermal dysplasia is a rare genetic disorder, with recessive transmission linked to X chromosome, characterized by the triad: hypo-/anhydrosis, hypo-/anodontia and hypotricosis/hair loss. Anodontia can be complete or partial (hypodontia, oligodontia). These anomalies of dentition may interest both primary and permanent dentition. In this paper, we present a series of eight cases identified based on clinical criteria, with the diagnosis of ectodermal dysplasia, at the “Alessandrescu-Rusescu” National Institute for Mother and Child Health, from Bucharest. The management of the patient with ectodermal dysplasia is complex and requires a multidisciplinary approach (pediatrician, geneticist, dentist, psychologist). Dental surgery and prosthetics (dental plaque ...
The first references to tele-dentistry were made in the 1990s when the US Army established the fi... more The first references to tele-dentistry were made in the 1990s when the US Army established the first dental project “Total Dental Acces” that allowed dental practitioners in a dental clinic from a base military to consult dentists specialists who were at a distance. After this, distance dental projects increased especially in the US, Europe, Australia and Brazil. Tele-dentistry is defined as a combination of telecommunication and dentistry, which involves the exchange of clinical information and images at distance, for dental consultation and treatment planning. Currently, using the technology available for these applications, dental professionals can display, record, sort, diagnose, and order remote care. Tele-dentistry can be available to anyone from an individual cabinet located in a rural or underprivileged area or in an urban clinic with state-of-the-art equipment and specialists in various areas of dental medicine. The authors outline a number of ways to use telemedici...
Journal of Community Positive Practices, 2018
Man's removal from the natural environment and his anthropocentric positioning in the anthrop... more Man's removal from the natural environment and his anthropocentric positioning in the anthropic environment are the result of a long cultural development. The path from man as part of nature to man as the master of nature goes through changing patterns of thought and action. Founding/cosmogonic myths have supported, in the consciousness of humanity, the feeling of belonging to nature as a place of genesis and the becoming of man. When man was no longer identified with nature and extracted from its systemic functioning, he became a user of the resources generously offered by nature. Thus, the development of human habitats was done with the decline of the natural environment and at the expense of the alienation of man from nature. The nature that gives us everything and does not request anything in return now appears as a lost paradise that we are looking for inside us. The operation of the natural environment on Earth is a model of systemic organization in which the intelligence ...
BMJ, 1985
Neonatal screening for congenital hypothyroidism was introduced in the City of Birmingham in 1980... more Neonatal screening for congenital hypothyroidism was introduced in the City of Birmingham in 1980 by measuring concentrations of both thyroid stimulating hormone and thyroxine in plasma. Over two years 30108 babies were tested. Thirty one babies were recalled because of thyroid stimulating hormone concentrations greater than 40 mU/l, of whom 12 were treated with replacement thyroxine. Six babies were found to have low thyroxine concentrations because of reduced thyroxine binding globulin and five raised thyroxine values because of increased thyroxine binding globulin. As a result of this study screening was continued with measurement of thyroid stimulating hormone only as the primary test for congenital hypothyroidism, the thyroxine value being measured only when the concentration of thyroid stimulating hormone exceeded 20 mU/l.
Romanian Journal of Legal Medicine, 2019
Romanian Journal of Legal Medicine, 2019
Annals of the Academy of Romanian Scientists Series on Biological Sciences
In the context of the increased prevalence of dental caries and periodontal disease reported in o... more In the context of the increased prevalence of dental caries and periodontal disease reported in our country, the extensive partial edentation is a common pathology, which requires complex treatment solutions. Implant-prosthetic therapy is the optimal treatment solution from a biological, functional and biomechanical point of view. Interdisciplinary management of implant-prosthetic therapy frequently involves the reconstruction of alveolar ridges in the pro-implant stage. The specialists in implantology and dento-alveolar surgery face the issue of the selection of grafting materials and techniques in relation to systemic, loco-regional, local factors and the planned prosthetic solution. In this context, a practical guide for the use of grafting materials and techniques may be useful to practitioners in order to optimize the aesthetic and functional results in the implant-prosthetic therapy of edentulous patients.
Social Science Research Network, Aug 23, 2016
Romanian Journal of Oral Rehabilitation, 2019
Abstract. As dental caries is a common disease with high prevalence worldwide, many researches ar... more Abstract. As dental caries is a common disease with high prevalence worldwide, many researches are focused nowadays on the longevity of direct composite restorations and indirect restorations both in the anterior and posterior dental substance loss. The mean survival rates of the direct composite restorations, after follow-up period of 3-10 years, are between 85,10% and 97,40%. The mean survival rates of the indirect coronal restorations, after follow-up period of 8-10 years, are between 90,40% and 100%. In the recovery of the esthetic and masticatory functions affected by coronal substance loss, the direct composite restorations and ceramic inlays or onlays have advantages and limits. The dentists must focus on factors related to material and technique as well as on clinical and biological factors, when a repair versus replacement decision must be taken
Romanian Journal of Medical and Dental Education, 2019
To increase the effectiveness of the dental prevention and therapeutic politics, World Health Org... more To increase the effectiveness of the dental prevention and therapeutic politics, World Health Organisation has focused the projects regarding the dental health on health insurance systems, social environment, as well as on cultural factors. Cultural factors related to oral health include concepts regarding ethiological factors and dental treatment, race, geographic area, family habits and influence, gender factor, socioeconomic factors, nutritional factors, and cultural beliefs and taboos. Unfavourable anthropological factors are associated both with high prevalence of the edentation in Romania and difficulties to apply the most appropriate prosthetic solutions for the long term success. Romania has a close collaboration with WHO (project Oral Health Programme) to initiate programs, focused on various cultural and demographic factors, aiming to improve the oral health status
Annals of the Academy of Romanian Scientists Series on Biological Sciences
Digital expert systems, commonly used in medicine, can be implemented successfully in the analysi... more Digital expert systems, commonly used in medicine, can be implemented successfully in the analysis and planning of treatments in dentistry. In implant-prosthetic therapy, these software applications epresent necessary adjuvant tools in optimizing therapeutic decisions regarding the pro-implant and implant stages as well as in creating a therapeutic planning algorithm. PRODENT Acad Expert (data recording and database) and PRODENT Indices (calculation of biological indices and recommendation for the optimal treatment solution) (Neo-Tech, Romania) are tools that allows the registration and entry of data in the database, registration of clinical and biological indices in pretreatment and post-implant stage, respectively the recommendation of an optimal prosthetic solution. The use of this application is necessary in monitoring changes related to the biological components of the stomatognathic system in postimplant stage. Expert applications for the assessment of mucosal and bone support...
Romanian Journal of Medical and Dental Education, 2019
The active mastication has not only role in food intake and digestion, but also in the maintainin... more The active mastication has not only role in food intake and digestion, but also in the maintaining and promotion of the cognitive functions. It was demonstrated the increase of the blood supply in neuronal areas during mastication due to the stimulation of dental baroreceptors, alveolar baroreceptors and masticatory muscles during. Chewing was associated with greater alertness, more positive mood, faster reaction times, improved focus as well as with the improvement of the learning ability. On the other part, epidemiologic studies found that elderly individuals with high number of absent teeth are more likely to develop cognitive dysfunction, and neurodegenerative diseases like Alzheimer and dementia.
Romanian Journal of Medical and Dental Education, 2021
Contemporary human diet is a major cause of tooth decay and other systemic diseases, such as diab... more Contemporary human diet is a major cause of tooth decay and other systemic diseases, such as diabetes, obesity and cardiovascular disease. Since the quantitative relationship between food principles is an important prophylactic factor of health, qualitative research in the form of theoretical review of specialty literature and experimental case studies has been carried out, with the aim of highlighting the roles of food principles for the prophylaxis of oral lesions, tooth decay and general oral health. The conclusions converge to the unsurprising perspective that the lack of dietary principles, the lack of proteins, for example, during the development of dental enamel matrix, favors the appearance of caries, while an excess of lipids decrease their incidence. Exogenous prophylaxis through diet of tooth decay is achieved by eating foods with increased consistency, which have a mechanical brushing role. Diet must be balanced by dietary principles: low in refined sugars and rich in vi...
Romanian Journal of Medical Practice, 2019
Candidoza orală este o infecţie a cavităţii orale cauzată de către Candida albicans. Mai mulţi fa... more Candidoza orală este o infecţie a cavităţii orale cauzată de către Candida albicans. Mai mulţi factori pot contribui la dezvoltarea candidozei precum: utilizarea protezelor, inhalatoarelor de corticosteroizi, xerostomia, stări de imunosupresie (cum ar fi infecţia cu virusul imunodeficienţei umane (HIV), leucemie, malnutriţie, scăderea imunităţii secundară vârstei, disfuncţie endocrină, cum ar fi diabetul, chimioterapie sistemică, terapie cu radiaţii, utilizarea de corticosteroizi sistemici).
Romanian Journal of Medical and Dental Education, 2019
Intercalated edentations have high prevalence both in anterior and lateral prosthetic areas. Vari... more Intercalated edentations have high prevalence both in anterior and lateral prosthetic areas. Various prosthetic solutions can be proposed for these clinical situations, including fixed bridges, hybrid prosthesis, or implant-prosthetic rehabilitation. Financial reasons or abutment teeth affected by severe periodontal disease, can conduct to the replacement of these prosthetic solutions with removable dentures but the oral hygiene as well as the period of adaptation and restoration of functions are more difficult. Pro-prosthetic treatments, crown lengthening and surgery procedures (augmentation associated or not to guided bone regeneration technique) on the level of the alveolar ridge, must be considered to improve the biological and clinical indices of the prosthetic area. The decisional processes are dealing with a great number of variables which need beeing evaluated and correlated with clinical factors, technological solutions, financial costs and patients' demands.
Archives of the Balkan Medical Union, 2019
Caractéristiques psychologiques des maladies orales chez les personnes âgées
Revista Medicală Română, Dec 31, 2019
Melasma este o afecțiune cronică a pielii, caracterizată prin macule brune neregulate, distribuit... more Melasma este o afecțiune cronică a pielii, caracterizată prin macule brune neregulate, distribuite simetric pe zonele expuse la soare ale corpului, în special pe față. Deși în general reprezintă doar o problemă "cosmetică", melasma poate afecta semnificativ calitatea vieții pacienților. Patogenia sa nu este încă pe deplin înțeleasă, fiind propuși mai mulți factori posibil declanșatori. În continuare, vom aborda anumite aspecte ale melasmei, în funcție de cercetările actuale.
Anodontia is a rare genetic disorder, characterized by the partial or complete absence of dentiti... more Anodontia is a rare genetic disorder, characterized by the partial or complete absence of dentition. It is rarely found in an isolated form, most of the time being associated with genetic syndromes such as ectodermal dysplasia. Ectodermal dysplasia is a rare genetic disorder, with recessive transmission linked to X chromosome, characterized by the triad: hypo-/anhydrosis, hypo-/anodontia and hypotricosis/hair loss. Anodontia can be complete or partial (hypodontia, oligodontia). These anomalies of dentition may interest both primary and permanent dentition. In this paper, we present a series of eight cases identified based on clinical criteria, with the diagnosis of ectodermal dysplasia, at the “Alessandrescu-Rusescu” National Institute for Mother and Child Health, from Bucharest. The management of the patient with ectodermal dysplasia is complex and requires a multidisciplinary approach (pediatrician, geneticist, dentist, psychologist). Dental surgery and prosthetics (dental plaque ...
The first references to tele-dentistry were made in the 1990s when the US Army established the fi... more The first references to tele-dentistry were made in the 1990s when the US Army established the first dental project “Total Dental Acces” that allowed dental practitioners in a dental clinic from a base military to consult dentists specialists who were at a distance. After this, distance dental projects increased especially in the US, Europe, Australia and Brazil. Tele-dentistry is defined as a combination of telecommunication and dentistry, which involves the exchange of clinical information and images at distance, for dental consultation and treatment planning. Currently, using the technology available for these applications, dental professionals can display, record, sort, diagnose, and order remote care. Tele-dentistry can be available to anyone from an individual cabinet located in a rural or underprivileged area or in an urban clinic with state-of-the-art equipment and specialists in various areas of dental medicine. The authors outline a number of ways to use telemedici...
Journal of Community Positive Practices, 2018
Man's removal from the natural environment and his anthropocentric positioning in the anthrop... more Man's removal from the natural environment and his anthropocentric positioning in the anthropic environment are the result of a long cultural development. The path from man as part of nature to man as the master of nature goes through changing patterns of thought and action. Founding/cosmogonic myths have supported, in the consciousness of humanity, the feeling of belonging to nature as a place of genesis and the becoming of man. When man was no longer identified with nature and extracted from its systemic functioning, he became a user of the resources generously offered by nature. Thus, the development of human habitats was done with the decline of the natural environment and at the expense of the alienation of man from nature. The nature that gives us everything and does not request anything in return now appears as a lost paradise that we are looking for inside us. The operation of the natural environment on Earth is a model of systemic organization in which the intelligence ...