Angela Gusiyska - Academia.edu (original) (raw)

Papers by Angela Gusiyska

Research paper thumbnail of Impact of the Passive/Active Ultrasonic Activation on the Endodontic Irrigants Effectiveness - a Review

Journal of IMAB - Annual Proceeding (Scientific Papers)

Introduction: various irrigation devices and chemical solutions are being developed and improved ... more Introduction: various irrigation devices and chemical solutions are being developed and improved nowadays for better penetration deep into the complex root canal system. Activation of irrigating solutions enhances the solution effectiveness. Evidence in the literature suggests that ultrasonic irrigation is much more effective in this respect than syringe irrigation alone. Passive ultrasonic irrigation (PUI) and/or ultrasonically activated irrigation (UAI): nowadays, the two terms, PUI and UAI, are interchangeable in the literature and represent the same technique. Literature data have shown that combining ultrasonically activated NaOCl with EDTA results in significantly greater removal of the smear layer. Conclusion: the use of ultrasonic activation of the irrigating solution after root canal preparation significantly improves the removal of debris from hard-to-reach areas such as isthmuses, lateral canals and the apical delta.

Research paper thumbnail of Clinical Approaches to the Three-Dimensional Endodontic Obturation Protocol for Teeth with Periapical Bone Lesions

Applied Sciences

Knowledge of dental anatomy and the three-dimensional principles of debridement, sterilization an... more Knowledge of dental anatomy and the three-dimensional principles of debridement, sterilization and obturation is necessary for effective root canal treatment. The chemo–mechanical preparation of the root canal biomechanically significantly reduces the number of microorganisms present. However, research has demonstrated that microorganisms frequently persist. The antimicrobial effect of the irrigants is essential to their biological function. Several obturation techniques are currently available, the selection of which depends on the canal’s morphology and the individual therapeutic goals of each instance. New sealing materials and methods for regenerative root canal obturation are enhancing and improving the predictability of three-dimensional (3D) sealing procedures. Epoxy sealers and gutta-percha are currently employed by clinicians as the gold standard in obturation procedures. The most recent developments in endodontic sealing materials are related to bioceramic sealers. Reports...

Research paper thumbnail of Micro-Computed Tomography Assessment of the Root Canal System

Journal of IMAB - Annual Proceeding (Scientific Papers)

Introduction: The root canal system (RCS) is among the complex parts of the body that consists of... more Introduction: The root canal system (RCS) is among the complex parts of the body that consists of several anatomical variations. The RCS has also been classified according to different classifications. In one of the classification systems, the RCS consists of the main canal, lateral canal, collateral canal, secondary canal, intercanal, accessory canal (AC), and recurrent canal, whereas in the other classification system, which was presented by the American Association of Endodontists (AAE) in 2020, the RCS consists of the C-shaped canal, lateral canal, furcation canal, and AC. Many researches have already been conducted on using micro-CT in describing the RCS classification in various teeth groups in the jaws. The micro-CT is a method used for the endodontic study, including the morphological study of the RCS. It is one of the non-destructive and high-resolution techniques that is beneficial in obtaining three-dimensional (3D) teeth structures. The method is similar to computed tomo...

Research paper thumbnail of Vertical root fractures in teeth with endodontic treatment - literature review

Journal of Medical and Dental Practice

Research paper thumbnail of An in vitro study of nano-scaling biphasic calcium- phosphate ceramic/ hyaluronan as dentine coating material

Research paper thumbnail of Retrospective study of the healing processes of endodontically treated teeth characterized by osteolytic defects of the periapical area: four-year follow-up

Biotechnology & Biotechnological Equipment, 2016

One of the main objectives of primary endodontic treatment is the prevention of periapical tissue... more One of the main objectives of primary endodontic treatment is the prevention of periapical tissue changes which, in the majority of clinical cases in general practice, does not take place because of the availability of a wide range of precise endodontic instruments. The healing process of the periapical area in teeth with inflammatory bone destruction is still a challenge in contemporary endodontic practice. The aim of this retrospective study was to assess the postoperative healing process of teeth with osteolytic defects in the periapical area. Eightynine endodontically treated teeth (n D 89) were included in the study. The teeth with necrotic pulp and without detectable periapical lesions were successfully treated in 92.9% of the cases. All of the incisors, canines and premolars showed significantly higher probabilities of success (97.8%) than molars (90.9%; P D 0.036). In all monitored teeth, the maxillary first molars with periapical index (PAI) 1 (80.2%), mandibular premolars with PAI3 (75%) and mandibular molars with PAI5 (75%) had the lowest rates of treatment success. In this study, the success rate of teeth with pulp necrosis complicated with a periapical lesion was 89.75% (P > 0.05). The analysis of the results from this study confirmed that the exact orthograde retreatment of the cases with osteolytic defects of the periapical area led to satisfactory healing and regeneration in the periapical area.

Research paper thumbnail of ENDODONTIC TREATMENT OF A SECOND MAXILLARY MOLAR WITH FIVE ROOT CANALS – A Case Report

Journal of IMAB - Annual Proceeding (Scientific Papers), 2010

ITRODUCTION: Knowledge of the internal dental morphology is a complex and extremely important poi... more ITRODUCTION: Knowledge of the internal dental morphology is a complex and extremely important point for planning and performing of endodontic treatment. CASE REPORT: The subject of this study was a clinical case of a second maxillary molar with five root canals-one canal in the palatal root, one canal in the distobuccal root and three canals in mesiobuccal root. DISCUSSION: Successful root canal treatment depends on proper cleaning, shaping and compact filling of the root canal under aseptic conditions. In order to achieve these, clinicians need to know thoroughly the morphology of the individual root canal and atypical root canal configuration. The mesiobuccal root of the maxillary first molar has generated more research, clinical investigation, and pure frustration than probably any other root in the mouth. CONCLUDING REMARKS: Endodontic research and technology are continually evolving to enable practitioners to identify, disinfect and obturate root canal system predictably and efficiently. Since the ultimate goal for patients and practitioners alike is the retention of natural teeth for a lifetime, endodontic therapy remains, and will continue to be, the primary treatment choice for teeth with pulpal and periradicular pathology. Magnification has been found to increase the detection rate of additional canals from 17,2% with the naked eye, to 62,5% with loupes and 71,1% using the surgical operating microscope.

Research paper thumbnail of Periapical Resorptive Processes in Chronic Apical Periodontitis: An Overview and Discussion of the Literature

Journal of IMAB - Annual Proceeding (Scientific Papers), 2014

Research paper thumbnail of Histologic and Electron Microscopic Periapical Tissue Examination Results in Teeth with Chronic Apical Periodontitis

Journal of IMAB - Annual Proceeding (Scientific Papers), 2014

Research paper thumbnail of In Vivo Analysis of Some Key Characteristics of the Apical Zone in Teeth with Chronic Apical Periodontitis

Journal of IMAB - Annual Proceeding (Scientific Papers), 2014

Research paper thumbnail of REMODELING OF PERIAPICAL LESIONS SCAFFOLDING BY BIPHASE CALCIUM PHOSPHATE CERAMICS - A Pilot Study

Journal of IMAB - Annual Proceeding (Scientific Papers), 2010

Introduction: Typical chronic apical periodontitis is generally accompanied by periapical bone de... more Introduction: Typical chronic apical periodontitis is generally accompanied by periapical bone destruction, which is radiographically observed as periapical radiolucency around the apex. Pathological events in apical periodontitis are mainly characterized by bone destruction and this bone destruction is mediated by osteoclasts which are multinuclear cells derived from macrophages. Although bone tissue possesses the capacity for regeneration, there are many pathological situations in which this capacity is not sufficient to stimulate and realize healing processes. The development of biphasic calcium phosphate ceramic for bone graft is one of the promising biomaterials for better control of the complex processes of bone healing and regeneration. Materials and Ìethods: The subject of this study were seven clinical cases (seven patients-4 female and 3 male in ages from 22-53 years) with radiolucency and radiographical evidence of periapical lesions. The result of this treatment was presented in three groups: I) three of root canals were aseptically instrumented to ISO size 60 (# 11, 46, 21), II) two of them-to ISO size 70 (# 11,36), and III) the third group to ISO size 80 (# 21,22) (Fig.2). Following the ideology of the injectable implant material [37], this study used as, scaffold fine powder particles of biphase calcium phosphate ceramic mixed with saline solution. Results: The results of this study are presented in the radiographs listed as Fig. 5, 9, 10 preoperatively and Fig. 6, 7, 8, 11, 12, 13 and 14 postoperatively. The sequence of replacement of radiolucency with a radioopacity in periapex should be considered as one of the characteristics in remodeling of the processes after treatment. These findings showed that in a lapse of time the healing processes involve immature bone and fibrous connective tissues. Discussion: Our positive results are insufficient for suggesting any possible mechanisms expanding healing processes of lesions. But having in mind some data from the literature on bone regeneration, molecular and cellular interaction with calcium phosphate ceramics, it should be mentioned that some results have demonstrated that microporosity and surface activity of ceramic is responsible

Research paper thumbnail of SEM investigation of canal wall dentine irrigated with chitosan solutions – A preliminary report

Research paper thumbnail of Evaluation of the Pulp Vitality in Patients with Periodontitis

Background: Periodontitis and pulpitis are caused by bacterial infections and its interactions ar... more Background: Periodontitis and pulpitis are caused by bacterial infections and its interactions are well documented in the literature. It has been reported that the pulp of teeth with persisting periodontal disease develops fibrosis and some forms of mineralization. Lesions of the periodontium may reflect the pulpal conditions and lead to pulp inflammation and necrosis. Bacterial infection from the periodontal pocket may spread trough accessory canals to the pulp and cause pulp injury. In the advanced periodontal disease infection may spread trough the apical foramen. However many periodontally affected teeth show no evidence of pulpal involvement. Aim: Evaluation of the pulp vitality in patients with moderate or advanced periodontitis.

Research paper thumbnail of Ортоградно лечение на хронични апикални периодонтити – биологични подходи

Дисертационен труд за придобиване на образователна и научна степен „доктор” Научна специалност: 0... more Дисертационен труд за придобиване на образователна и научна степен „доктор” Научна специалност: 03.03.01. Терапевтична стоматология, Научен ръководител: Проф. д-р Елена Дюлгерова, дм, дх, дмн Научен консултант: Проф. д-р Ангелина Киселова-Янева, дм, дмн Рецензенти: Проф. д-р Стоян Владимиров, дм, дмн, Доц. Д-р Снежанка Топалова-Пиринска, дм София, 2012 г.

Research paper thumbnail of Analysis of Microbiological Results in Teeth with Chronic Apical Periodontitis

International Journal of Science and Research (IJSR)

The invasion of the living microorganisms and their toxic products in endodontium and periapical ... more The invasion of the living microorganisms and their toxic products in endodontium and periapical structures is a significant problem in chronic apical periodontitis (CAP).This study analyzed the microbiological results of teeth with CAP.Microorganisms were isolated from the infected root canals of teeth with chronic apical periodontitis (primary or secondary) with or without the absence of clinical signs and symptoms. The microbiological diagnosis was made based on 79 teeth from 79 patients who fulfilled the inclusion criteria (n=79; 38 single-rooted and 41 multi-rooted teeth/36 females and 43 males) with an average age of 40 years (age range = 18-62). The study investigated teeth with CAP with or without an endodontic treatment. The data was inputted and processed using statistical package SPSS 15.0.1.E. faecalis was the most frequently isolated microorganism (68.6%). The analysis of microbiological results in primary CAP (Group II) showed that there were no isolated microorganisms in 78.6% of the cases (22 cases). In contrast, in Group I, the first microbiological sample results were positive, with bacterial growth at 92.2% (47 cases).E. faecalis is a typical microflora in persistent CAPs performed with unsatisfactory endodontic treatment, and it is not isolated from teeth with primary CAP. E. faecalis is a resistant microorganism even after the application of chemomechanical preparation of the endodontic space.

Research paper thumbnail of Orthograde Apical Application of an MTA Plug in a Tooth without Constriction - A Case Report

International Journal of Science and Research (IJSR)

The periapical area in teeth with chronic lesions is characterized by changes in the adjacent bon... more The periapical area in teeth with chronic lesions is characterized by changes in the adjacent bone structure and periodontal ligaments, as well as in the cement and dentine. In a large percentage of cases, the apical physiological constriction is ether absent or expanded. The absence of a constriction makes it a challenge to achieve satisfactory treatment results.The present case report describes the re-treatment of a case of a mandibular molar, complicated by lack of constriction and a separated endodontic instrument. Mineral trioxide aggregate (MTA) was used for a 5-mm apical plug to avoid overfilling of the sealer when the root canal was definitely obturated. The periapical radiographs showed satisfactory images of periapical bone density and the tooth was asymptomatic on precision. MTA is proved to be an appropriate material for apical sealing in cases with resorption, as it leads to avoidance of apical surgical procedures with a similar prognostic outcome.

Research paper thumbnail of Repair of Periapical Structures in Apical Periodontitis Using Two Step Method

INTRODUCTION: Apical periodontitis is a result of infection in root canal system and manifestatio... more INTRODUCTION: Apical periodontitis is a result of infection in root canal system and manifestation of the host defense response. The aim of this study is to compare radiographically regeneration of periapical lesions in roots with infected root canals obturated with calcium hydroxide

Research paper thumbnail of Evaluation of the Pulp Vitality in Patients with Periodontitis

Background: Periodontitis and pulpitis are caused by bacterial infections and its interactions ar... more Background: Periodontitis and pulpitis are caused by bacterial infections and its interactions are well documented in the literature. It has been reported that the pulp of teeth with persisting periodontal disease develops fibrosis and some forms of mineralization. Lesions of the periodontium may reflect the pulpal conditions and lead to pulp inflammation and necrosis. Bacterial infection from the periodontal pocket may spread trough accessory canals to the pulp and cause pulp injury. In the advanced periodontal disease infection may spread trough the apical foramen. However many periodontally affected teeth show no evidence of pulpal involvement. Aim: Evaluation of the pulp vitality in patients with moderate or advanced periodontitis. Material and method: We examinated pulp vitality of 156 teeth in 18 patients who received periodontal treatment. Teeth were assessed for oral hygiene status, gingival status and periodontal status. Results: Received results didn’t show that periodonta...

Research paper thumbnail of Incidence, location and sizes of the accessory mental foramina in Bulgarian population assessed by cone-beam computed tomography

Biomedical Research-tokyo, 2017

The purpose of this study was to assess the incidence, location, and sizes of the accessory menta... more The purpose of this study was to assess the incidence, location, and sizes of the accessory mental foramina in Bulgarian population using Cone-Beam Computed Tomography (CBCT). The CBCT records of 1400 Bulgarian patients were evaluated for Accessory Mental Foramina (AMF) by two expert radiologists familiar with CBCT interpretation. Their presence and location in relation to the Mental Foramen (MF) were assessed using axial, panoramic and cross-sectional 2-dimensional CBCT images. The long and short axes diameters of the AMF were also measured. Accessory mental foramina were observed in 3.86% of the patients: up to two foramina on one side, unilaterally presented in 94.4% of cases with AMF. Their location regarding MF was distally and inferiorly in 62.9%. In 35.5 % of cases with AMF the foramen was situated above the level of MF and therefore needs special attention before surgery. The mean inner long and short axis diameters were 1.5 mm (SD: 0.4 mm) and 1.2 mm (SD: 0.3 mm) respective...

Research paper thumbnail of Cervical margin relocation - basic principles and influence on the periodontal tissues

INTRODUCTION: Cervical margin relocation (CMR) involves the placement of a base layer of direct r... more INTRODUCTION: Cervical margin relocation (CMR) involves the placement of a base layer of direct resin composite material in order to elevate the proximal cavity margins located below the gingiva. CMR is applied prior to the cementation of indirect bonded restorations. AIM: The aim of this review is to briefly present the basic principles of the CMR technique and to assess whether the execution of this method before the cementation of indirect bonded restorations is beneficial to the long-term outcome of the treatment and to the periodontal tissues according to the literature. MATERIALS AND METHODS: This review includes articles searched without date restriction in the Medline/PubMed database along with bibliographic data. A variety of keywords and their combinations were used: "cervical margin relocation", "proximal box elevation", "indirect restorations", "adhesion", "marginal adaptation", "marginal sealing", "deep ma...

Research paper thumbnail of Impact of the Passive/Active Ultrasonic Activation on the Endodontic Irrigants Effectiveness - a Review

Journal of IMAB - Annual Proceeding (Scientific Papers)

Introduction: various irrigation devices and chemical solutions are being developed and improved ... more Introduction: various irrigation devices and chemical solutions are being developed and improved nowadays for better penetration deep into the complex root canal system. Activation of irrigating solutions enhances the solution effectiveness. Evidence in the literature suggests that ultrasonic irrigation is much more effective in this respect than syringe irrigation alone. Passive ultrasonic irrigation (PUI) and/or ultrasonically activated irrigation (UAI): nowadays, the two terms, PUI and UAI, are interchangeable in the literature and represent the same technique. Literature data have shown that combining ultrasonically activated NaOCl with EDTA results in significantly greater removal of the smear layer. Conclusion: the use of ultrasonic activation of the irrigating solution after root canal preparation significantly improves the removal of debris from hard-to-reach areas such as isthmuses, lateral canals and the apical delta.

Research paper thumbnail of Clinical Approaches to the Three-Dimensional Endodontic Obturation Protocol for Teeth with Periapical Bone Lesions

Applied Sciences

Knowledge of dental anatomy and the three-dimensional principles of debridement, sterilization an... more Knowledge of dental anatomy and the three-dimensional principles of debridement, sterilization and obturation is necessary for effective root canal treatment. The chemo–mechanical preparation of the root canal biomechanically significantly reduces the number of microorganisms present. However, research has demonstrated that microorganisms frequently persist. The antimicrobial effect of the irrigants is essential to their biological function. Several obturation techniques are currently available, the selection of which depends on the canal’s morphology and the individual therapeutic goals of each instance. New sealing materials and methods for regenerative root canal obturation are enhancing and improving the predictability of three-dimensional (3D) sealing procedures. Epoxy sealers and gutta-percha are currently employed by clinicians as the gold standard in obturation procedures. The most recent developments in endodontic sealing materials are related to bioceramic sealers. Reports...

Research paper thumbnail of Micro-Computed Tomography Assessment of the Root Canal System

Journal of IMAB - Annual Proceeding (Scientific Papers)

Introduction: The root canal system (RCS) is among the complex parts of the body that consists of... more Introduction: The root canal system (RCS) is among the complex parts of the body that consists of several anatomical variations. The RCS has also been classified according to different classifications. In one of the classification systems, the RCS consists of the main canal, lateral canal, collateral canal, secondary canal, intercanal, accessory canal (AC), and recurrent canal, whereas in the other classification system, which was presented by the American Association of Endodontists (AAE) in 2020, the RCS consists of the C-shaped canal, lateral canal, furcation canal, and AC. Many researches have already been conducted on using micro-CT in describing the RCS classification in various teeth groups in the jaws. The micro-CT is a method used for the endodontic study, including the morphological study of the RCS. It is one of the non-destructive and high-resolution techniques that is beneficial in obtaining three-dimensional (3D) teeth structures. The method is similar to computed tomo...

Research paper thumbnail of Vertical root fractures in teeth with endodontic treatment - literature review

Journal of Medical and Dental Practice

Research paper thumbnail of An in vitro study of nano-scaling biphasic calcium- phosphate ceramic/ hyaluronan as dentine coating material

Research paper thumbnail of Retrospective study of the healing processes of endodontically treated teeth characterized by osteolytic defects of the periapical area: four-year follow-up

Biotechnology & Biotechnological Equipment, 2016

One of the main objectives of primary endodontic treatment is the prevention of periapical tissue... more One of the main objectives of primary endodontic treatment is the prevention of periapical tissue changes which, in the majority of clinical cases in general practice, does not take place because of the availability of a wide range of precise endodontic instruments. The healing process of the periapical area in teeth with inflammatory bone destruction is still a challenge in contemporary endodontic practice. The aim of this retrospective study was to assess the postoperative healing process of teeth with osteolytic defects in the periapical area. Eightynine endodontically treated teeth (n D 89) were included in the study. The teeth with necrotic pulp and without detectable periapical lesions were successfully treated in 92.9% of the cases. All of the incisors, canines and premolars showed significantly higher probabilities of success (97.8%) than molars (90.9%; P D 0.036). In all monitored teeth, the maxillary first molars with periapical index (PAI) 1 (80.2%), mandibular premolars with PAI3 (75%) and mandibular molars with PAI5 (75%) had the lowest rates of treatment success. In this study, the success rate of teeth with pulp necrosis complicated with a periapical lesion was 89.75% (P > 0.05). The analysis of the results from this study confirmed that the exact orthograde retreatment of the cases with osteolytic defects of the periapical area led to satisfactory healing and regeneration in the periapical area.

Research paper thumbnail of ENDODONTIC TREATMENT OF A SECOND MAXILLARY MOLAR WITH FIVE ROOT CANALS – A Case Report

Journal of IMAB - Annual Proceeding (Scientific Papers), 2010

ITRODUCTION: Knowledge of the internal dental morphology is a complex and extremely important poi... more ITRODUCTION: Knowledge of the internal dental morphology is a complex and extremely important point for planning and performing of endodontic treatment. CASE REPORT: The subject of this study was a clinical case of a second maxillary molar with five root canals-one canal in the palatal root, one canal in the distobuccal root and three canals in mesiobuccal root. DISCUSSION: Successful root canal treatment depends on proper cleaning, shaping and compact filling of the root canal under aseptic conditions. In order to achieve these, clinicians need to know thoroughly the morphology of the individual root canal and atypical root canal configuration. The mesiobuccal root of the maxillary first molar has generated more research, clinical investigation, and pure frustration than probably any other root in the mouth. CONCLUDING REMARKS: Endodontic research and technology are continually evolving to enable practitioners to identify, disinfect and obturate root canal system predictably and efficiently. Since the ultimate goal for patients and practitioners alike is the retention of natural teeth for a lifetime, endodontic therapy remains, and will continue to be, the primary treatment choice for teeth with pulpal and periradicular pathology. Magnification has been found to increase the detection rate of additional canals from 17,2% with the naked eye, to 62,5% with loupes and 71,1% using the surgical operating microscope.

Research paper thumbnail of Periapical Resorptive Processes in Chronic Apical Periodontitis: An Overview and Discussion of the Literature

Journal of IMAB - Annual Proceeding (Scientific Papers), 2014

Research paper thumbnail of Histologic and Electron Microscopic Periapical Tissue Examination Results in Teeth with Chronic Apical Periodontitis

Journal of IMAB - Annual Proceeding (Scientific Papers), 2014

Research paper thumbnail of In Vivo Analysis of Some Key Characteristics of the Apical Zone in Teeth with Chronic Apical Periodontitis

Journal of IMAB - Annual Proceeding (Scientific Papers), 2014

Research paper thumbnail of REMODELING OF PERIAPICAL LESIONS SCAFFOLDING BY BIPHASE CALCIUM PHOSPHATE CERAMICS - A Pilot Study

Journal of IMAB - Annual Proceeding (Scientific Papers), 2010

Introduction: Typical chronic apical periodontitis is generally accompanied by periapical bone de... more Introduction: Typical chronic apical periodontitis is generally accompanied by periapical bone destruction, which is radiographically observed as periapical radiolucency around the apex. Pathological events in apical periodontitis are mainly characterized by bone destruction and this bone destruction is mediated by osteoclasts which are multinuclear cells derived from macrophages. Although bone tissue possesses the capacity for regeneration, there are many pathological situations in which this capacity is not sufficient to stimulate and realize healing processes. The development of biphasic calcium phosphate ceramic for bone graft is one of the promising biomaterials for better control of the complex processes of bone healing and regeneration. Materials and Ìethods: The subject of this study were seven clinical cases (seven patients-4 female and 3 male in ages from 22-53 years) with radiolucency and radiographical evidence of periapical lesions. The result of this treatment was presented in three groups: I) three of root canals were aseptically instrumented to ISO size 60 (# 11, 46, 21), II) two of them-to ISO size 70 (# 11,36), and III) the third group to ISO size 80 (# 21,22) (Fig.2). Following the ideology of the injectable implant material [37], this study used as, scaffold fine powder particles of biphase calcium phosphate ceramic mixed with saline solution. Results: The results of this study are presented in the radiographs listed as Fig. 5, 9, 10 preoperatively and Fig. 6, 7, 8, 11, 12, 13 and 14 postoperatively. The sequence of replacement of radiolucency with a radioopacity in periapex should be considered as one of the characteristics in remodeling of the processes after treatment. These findings showed that in a lapse of time the healing processes involve immature bone and fibrous connective tissues. Discussion: Our positive results are insufficient for suggesting any possible mechanisms expanding healing processes of lesions. But having in mind some data from the literature on bone regeneration, molecular and cellular interaction with calcium phosphate ceramics, it should be mentioned that some results have demonstrated that microporosity and surface activity of ceramic is responsible

Research paper thumbnail of SEM investigation of canal wall dentine irrigated with chitosan solutions – A preliminary report

Research paper thumbnail of Evaluation of the Pulp Vitality in Patients with Periodontitis

Background: Periodontitis and pulpitis are caused by bacterial infections and its interactions ar... more Background: Periodontitis and pulpitis are caused by bacterial infections and its interactions are well documented in the literature. It has been reported that the pulp of teeth with persisting periodontal disease develops fibrosis and some forms of mineralization. Lesions of the periodontium may reflect the pulpal conditions and lead to pulp inflammation and necrosis. Bacterial infection from the periodontal pocket may spread trough accessory canals to the pulp and cause pulp injury. In the advanced periodontal disease infection may spread trough the apical foramen. However many periodontally affected teeth show no evidence of pulpal involvement. Aim: Evaluation of the pulp vitality in patients with moderate or advanced periodontitis.

Research paper thumbnail of Ортоградно лечение на хронични апикални периодонтити – биологични подходи

Дисертационен труд за придобиване на образователна и научна степен „доктор” Научна специалност: 0... more Дисертационен труд за придобиване на образователна и научна степен „доктор” Научна специалност: 03.03.01. Терапевтична стоматология, Научен ръководител: Проф. д-р Елена Дюлгерова, дм, дх, дмн Научен консултант: Проф. д-р Ангелина Киселова-Янева, дм, дмн Рецензенти: Проф. д-р Стоян Владимиров, дм, дмн, Доц. Д-р Снежанка Топалова-Пиринска, дм София, 2012 г.

Research paper thumbnail of Analysis of Microbiological Results in Teeth with Chronic Apical Periodontitis

International Journal of Science and Research (IJSR)

The invasion of the living microorganisms and their toxic products in endodontium and periapical ... more The invasion of the living microorganisms and their toxic products in endodontium and periapical structures is a significant problem in chronic apical periodontitis (CAP).This study analyzed the microbiological results of teeth with CAP.Microorganisms were isolated from the infected root canals of teeth with chronic apical periodontitis (primary or secondary) with or without the absence of clinical signs and symptoms. The microbiological diagnosis was made based on 79 teeth from 79 patients who fulfilled the inclusion criteria (n=79; 38 single-rooted and 41 multi-rooted teeth/36 females and 43 males) with an average age of 40 years (age range = 18-62). The study investigated teeth with CAP with or without an endodontic treatment. The data was inputted and processed using statistical package SPSS 15.0.1.E. faecalis was the most frequently isolated microorganism (68.6%). The analysis of microbiological results in primary CAP (Group II) showed that there were no isolated microorganisms in 78.6% of the cases (22 cases). In contrast, in Group I, the first microbiological sample results were positive, with bacterial growth at 92.2% (47 cases).E. faecalis is a typical microflora in persistent CAPs performed with unsatisfactory endodontic treatment, and it is not isolated from teeth with primary CAP. E. faecalis is a resistant microorganism even after the application of chemomechanical preparation of the endodontic space.

Research paper thumbnail of Orthograde Apical Application of an MTA Plug in a Tooth without Constriction - A Case Report

International Journal of Science and Research (IJSR)

The periapical area in teeth with chronic lesions is characterized by changes in the adjacent bon... more The periapical area in teeth with chronic lesions is characterized by changes in the adjacent bone structure and periodontal ligaments, as well as in the cement and dentine. In a large percentage of cases, the apical physiological constriction is ether absent or expanded. The absence of a constriction makes it a challenge to achieve satisfactory treatment results.The present case report describes the re-treatment of a case of a mandibular molar, complicated by lack of constriction and a separated endodontic instrument. Mineral trioxide aggregate (MTA) was used for a 5-mm apical plug to avoid overfilling of the sealer when the root canal was definitely obturated. The periapical radiographs showed satisfactory images of periapical bone density and the tooth was asymptomatic on precision. MTA is proved to be an appropriate material for apical sealing in cases with resorption, as it leads to avoidance of apical surgical procedures with a similar prognostic outcome.

Research paper thumbnail of Repair of Periapical Structures in Apical Periodontitis Using Two Step Method

INTRODUCTION: Apical periodontitis is a result of infection in root canal system and manifestatio... more INTRODUCTION: Apical periodontitis is a result of infection in root canal system and manifestation of the host defense response. The aim of this study is to compare radiographically regeneration of periapical lesions in roots with infected root canals obturated with calcium hydroxide

Research paper thumbnail of Evaluation of the Pulp Vitality in Patients with Periodontitis

Background: Periodontitis and pulpitis are caused by bacterial infections and its interactions ar... more Background: Periodontitis and pulpitis are caused by bacterial infections and its interactions are well documented in the literature. It has been reported that the pulp of teeth with persisting periodontal disease develops fibrosis and some forms of mineralization. Lesions of the periodontium may reflect the pulpal conditions and lead to pulp inflammation and necrosis. Bacterial infection from the periodontal pocket may spread trough accessory canals to the pulp and cause pulp injury. In the advanced periodontal disease infection may spread trough the apical foramen. However many periodontally affected teeth show no evidence of pulpal involvement. Aim: Evaluation of the pulp vitality in patients with moderate or advanced periodontitis. Material and method: We examinated pulp vitality of 156 teeth in 18 patients who received periodontal treatment. Teeth were assessed for oral hygiene status, gingival status and periodontal status. Results: Received results didn’t show that periodonta...

Research paper thumbnail of Incidence, location and sizes of the accessory mental foramina in Bulgarian population assessed by cone-beam computed tomography

Biomedical Research-tokyo, 2017

The purpose of this study was to assess the incidence, location, and sizes of the accessory menta... more The purpose of this study was to assess the incidence, location, and sizes of the accessory mental foramina in Bulgarian population using Cone-Beam Computed Tomography (CBCT). The CBCT records of 1400 Bulgarian patients were evaluated for Accessory Mental Foramina (AMF) by two expert radiologists familiar with CBCT interpretation. Their presence and location in relation to the Mental Foramen (MF) were assessed using axial, panoramic and cross-sectional 2-dimensional CBCT images. The long and short axes diameters of the AMF were also measured. Accessory mental foramina were observed in 3.86% of the patients: up to two foramina on one side, unilaterally presented in 94.4% of cases with AMF. Their location regarding MF was distally and inferiorly in 62.9%. In 35.5 % of cases with AMF the foramen was situated above the level of MF and therefore needs special attention before surgery. The mean inner long and short axis diameters were 1.5 mm (SD: 0.4 mm) and 1.2 mm (SD: 0.3 mm) respective...

Research paper thumbnail of Cervical margin relocation - basic principles and influence on the periodontal tissues

INTRODUCTION: Cervical margin relocation (CMR) involves the placement of a base layer of direct r... more INTRODUCTION: Cervical margin relocation (CMR) involves the placement of a base layer of direct resin composite material in order to elevate the proximal cavity margins located below the gingiva. CMR is applied prior to the cementation of indirect bonded restorations. AIM: The aim of this review is to briefly present the basic principles of the CMR technique and to assess whether the execution of this method before the cementation of indirect bonded restorations is beneficial to the long-term outcome of the treatment and to the periodontal tissues according to the literature. MATERIALS AND METHODS: This review includes articles searched without date restriction in the Medline/PubMed database along with bibliographic data. A variety of keywords and their combinations were used: "cervical margin relocation", "proximal box elevation", "indirect restorations", "adhesion", "marginal adaptation", "marginal sealing", "deep ma...