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Bio-fertilizers are one of the best modern tools and gift of our agricultural science as a replac... more Bio-fertilizers are one of the best modern tools and gift of our agricultural science as a replacement to our conventional fertilizers. Conventional fertilizers contain compost; household wastes and green manure and are not as effective as chemical fertilizers. So, farmers often try to use chemical fertilizers in the field for crop development. But obviously the chemical fertilizers are not environment friendly because of their chemical toxicity that can cause water, air and soil pollution and can spread cancer causing agents. Moreover, they may destroy the fertility of the soil in a long run. Scientists have developed the way of organic farming by use of “Bio-fertilizers” to prevent chemical pollution in farm lands. Bio-fertilizer contains microorganisms which promote the adequate supply of nutrients to the host plants and ensure their proper development of growth and regulation in their physiology. Living microorganisms are used in the preparation of Bio-fertilizers which have spe...
We report results of studies relating to the fabrication of a flexible, disposable, and label fre... more We report results of studies relating to the fabrication of a flexible, disposable, and label free biosensing platform for detection of the cancer biomarker (carcinoembryonic antigen, CEA). Polyaniline (PANI) has been electrochemically deposited over gold sputtered paper (Au@paper) for covalent immobilization of monoclonal carcinoembryonic antibodies (anti-CEA). The bovine serum albumin (BSA) has been used for blocking nonspecific binding sites at the anti-CEA conjugated PANI/Au@Paper. The PANI/Au@Paper, anti-CEA/PANI/Au@Paper, and BSA/anti-CEA/PANI/Au@Paper platforms have been characterized using scanning electron microscopy, X-ray diffraction, Fourier transmission infrared spectroscopy, chronoamperometry, and electrochemical impedance techniques. The results of the electrochemical response studies indicate that this BSA/anti-CEA/PANI/Au@paper electrode has sensitivity of 13.9 μA ng−1 ml cm2, shelf life of 22 days, and can be used to estimate CEA in the range of 2–20 ng ml−1. This paper sensor has been validated by detection of CEA in serum samples of cancer patients via immunoassay technique.
Bio-fertilizers are one of the best modern tools and gift of our agricultural science as a replac... more Bio-fertilizers are one of the best modern tools and gift of our agricultural science as a replacement to our conventional fertilizers. Conventional fertilizers contain compost; household wastes and green manure and are not as effective as chemical fertilizers. So, farmers often try to use chemical fertilizers in the field for crop development. But obviously the chemical fertilizers are not environment friendly because of their chemical toxicity that can cause water, air and soil pollution and can spread cancer causing agents. Moreover, they may destroy the fertility of the soil in a long run. Scientists have developed the way of organic farming by use of “Bio-fertilizers” to prevent chemical pollution in farm lands. Bio-fertilizer contains microorganisms which promote the adequate supply of nutrients to the host plants and ensure their proper development of growth and regulation in their physiology. Living microorganisms are used in the preparation of Bio-fertilizers which have spe...
We report results of studies relating to the fabrication of a flexible, disposable, and label fre... more We report results of studies relating to the fabrication of a flexible, disposable, and label free biosensing platform for detection of the cancer biomarker (carcinoembryonic antigen, CEA). Polyaniline (PANI) has been electrochemically deposited over gold sputtered paper (Au@paper) for covalent immobilization of monoclonal carcinoembryonic antibodies (anti-CEA). The bovine serum albumin (BSA) has been used for blocking nonspecific binding sites at the anti-CEA conjugated PANI/Au@Paper. The PANI/Au@Paper, anti-CEA/PANI/Au@Paper, and BSA/anti-CEA/PANI/Au@Paper platforms have been characterized using scanning electron microscopy, X-ray diffraction, Fourier transmission infrared spectroscopy, chronoamperometry, and electrochemical impedance techniques. The results of the electrochemical response studies indicate that this BSA/anti-CEA/PANI/Au@paper electrode has sensitivity of 13.9 μA ng−1 ml cm2, shelf life of 22 days, and can be used to estimate CEA in the range of 2–20 ng ml−1. This paper sensor has been validated by detection of CEA in serum samples of cancer patients via immunoassay technique.