Anita Pareek - Academia.edu (original) (raw)

Papers by Anita Pareek

Research paper thumbnail of Comparison of ropivacaine 0.5% with dexmedetomidine and clonidine as adjuvants in ultrasound-guided infraclavicular brachial plexus block for upper limb surgery

Journal of Applied Pharmaceutical Research

Background: The Institutional Ethics Committee and patients' informed written consent were ob... more Background: The Institutional Ethics Committee and patients' informed written consent were obtained before this study was carried out in the Department of Anaesthesiology at Sardar Patel Medical College in Bikaner, Rajasthan. An established method for delivering anaesthesia and analgesia during upper limb surgery is brachial plexus block. For peripheral nerve blocks, ropivacaine, a long-acting amide with a safe cardiac profile, is chosen. It has been proven that different adjuncts may be added to LA solutions to boost their effectiveness and longevity while lowering the overall dose of LA utilised and minimising any systemic side effects. Our goal was to assess the effectiveness of adjuvants such as dexmedetomidine and clonidine in comparison to 0.5% ropivacaine in an infraclavicular block for upper limb surgery under USG guidance. Method: Fifty adult patients planned for elective upperlimb surgery with an infraclavicular brachial plexus block under USG guidance were included. A...

Research paper thumbnail of Post-operative analgesic efficacy of fentanyl via different routes – A comparative study of nebulisation , intranasal and intravenous routes

Background: Pain is main post operative adverse outcomes causing patient distress, prolonging hos... more Background: Pain is main post operative adverse outcomes causing patient distress, prolonging hospital stay, and increasing the incidence of admissions after surgery. Study was done to assess and compare the post-operative analgesic effects of fentanyl via nebulisation, intranasal and intravenous routes to provide better analgesia, anxiolysis and sedation to the patient. Materials and methods: After approval from ethical committee of SPMC, Bikaner and written informed valid consent from patients, sixty patients of either sex belonging to ASA class I and II, were randomised into three group (Group I Nebulised Fentanyl, Group II Intranasal Fentanyl, Group III Intravenous Fentanyl). With all aseptic precaution, subarachnoid block was instilated via 23/25 gauze spinal needle by injecting sufficient dose of bupivacaine heavy 5% to achieve an adequate sensory and motor block for the proposed surgery. When patient complained pain 1 st time, fentanyl was given via nebulisation in group I, i...

Research paper thumbnail of To Compare the Effect of Dexmedetomidine and Clonidine as Adjuvant to Ropivacaine in Supraclavicular Brachial Plexus Block for Upper Limb Surgery

Background and Aim: Alpha-2 agonists as adjuvant to local anaesthetic agents for PNB enhance the ... more Background and Aim: Alpha-2 agonists as adjuvant to local anaesthetic agents for PNB enhance the quality and duration of analgesia. Aim of this prospective, double blind, randomised placebo controlled study was to compare the affect addition of Dexmedetomidine and clonidine to Ropivacaine with respect to onset, peak, and duration of sensory-motor block and duration of analgesia in Supraclavicular brachial plexus block. Materials and methods: Ninety ASA grade I or II patients of either sex, aged 18-60 years age scheduled for elective upper limb surgery were equally divided in three groups (n=30).Group R received 0.75% Ropivacaine 30 ml + 1ml NS, Group RC received 0.75% Ropivacaine 30ml +1μgm/kg of clonidine, Group RD received 0.75% Ropivacaine 30ml + 1μgm/kg of Dexmedetomidine in Supraclavicular plexus block by using nerve locator. Ashish Kumar Narolia, Kanta Bhati, Kuldeep Saini, Anita Pareek, Meera Kumari. To Compare the Effect of Dexmedetomidine and Clonidine as Adjuvant to Ropiva...

Research paper thumbnail of Comparison of conventional dose and low dose infusion of dexmedetomidine on hemodynamic stress response, dose of induction agent and postoperative analgesia in patients undergoing laparoscopic cholecystectomy

Background and Aim: Anesthetic techniques are based on hemodynamic stability during anesthesia an... more Background and Aim: Anesthetic techniques are based on hemodynamic stability during anesthesia and surgery. Dexmedetomidine is centrally acting α2 agonist with sedative, sympatholytic and analgesic. Aim of this study was to compare effect of conventional dose with low dose infusion of dexmedetomidine on hemodynamic stress response, induction agent requirement & postoperative analgesia. Materials and methods: Single randomised prospective study done on 100 ASA Ι and ΙΙ patients aged 18-65 years scheduled for elective laparoscopy cholecystectomy under general anesthesia. Patients were divided in to two groups of 50 each, Group A: 1 μg/kg loading dose of Rolaniya SL, Dhawan S, Meera Kumari, Jain R, Pareek A, Sehtia S. Comparison of conventional dose and low dose infusion of dexmedetomidine on hemodynamic stress response, dose of induction agent and postoperative analgesia in patients undergoing laparoscopic cholecystectomy. IAIM, 2017; 4(7): 111-117. Page 112 dexmedetomidine I.V. start...

Research paper thumbnail of A Comparative Evaluation of Dexmedetomidine, Propofol and Midazolam for Intraoperative Sedation in Regional Anaesthesia

Journal of Evolution of Medical and Dental Sciences, 2017

Research paper thumbnail of A Comparative Study of Dexmedetomidine and Clonidine as Premedicant on Intraocular Pressure and Haemodynamic Changes in Non-Ophthalmic Surgeries

Journal of Evolution of Medical and Dental Sciences, 2016

Research paper thumbnail of Fractionated dose versus bolus dose of isobaric injection ropivacaine (0.75%) for patients undergoing elective caesarean section under spinal anaesthesia: A randomized, double-blind study

Journal of applied pharmaceutical research, Aug 30, 2023

Background: Spinal anaesthesia (SA) using a bolus dose of Ropivacaine (0.75%) is known for its ra... more Background: Spinal anaesthesia (SA) using a bolus dose of Ropivacaine (0.75%) is known for its rapid onset but potential chances of hypotension. Administering Ropivacaine (0.75%) in fractions with intervals between the doses, has shown to establish a dense block, prolong analgesia and maintain better hemodynamic stability. This study aimed to compare the efficacy of fractionated and bolus doses of Ropivacaine (0.75%) in patients undergoing elective lower segment caesarean section (LSCS) under spinal anaesthesia. Methods: In a randomized, double-blinded trial, sixty patients scheduled for elective LSCS were enrolled and assigned to two groups. Group A received a single bolus spinal anaesthesia using Ropivacaine (0.75%) (2.5ml), while Group B received a fractionated dose approach: two-thirds of the total Ropivacaine (0.75%) dose (1.6ml) initially, followed by one-third dose (0.9ml) after 90 seconds. Results: The onset of sensory block (Group A: 3.59±1.31 min, Group B: 4.25±0.63 min) and motor block (Group A: 5.49±2.30 min, Group B: 7.34±11.28 min), as well as the duration of analgesia, were significantly longer in Group B (233.33±16.47 min) compared to Group A (185.17±20.61 min) (P<0.05). Hemodynamic stability was superior in Group B, with all patients showing better stability than those in Group A. Conclusion: Utilizing a fractionated dose of Ropivacaine (0.75%) in spinal anaesthesia results in an extended duration of analgesia and improved hemodynamic stability compared to a bolus dose approach.

Research paper thumbnail of Comparison of ropivacaine 0.5% with dexmedetomidine and clonidine as adjuvants in ultrasound-guided infraclavicular brachial plexus block for upper limb surgery

Journal of Applied Pharmaceutical Research

Background: The Institutional Ethics Committee and patients' informed written consent were ob... more Background: The Institutional Ethics Committee and patients' informed written consent were obtained before this study was carried out in the Department of Anaesthesiology at Sardar Patel Medical College in Bikaner, Rajasthan. An established method for delivering anaesthesia and analgesia during upper limb surgery is brachial plexus block. For peripheral nerve blocks, ropivacaine, a long-acting amide with a safe cardiac profile, is chosen. It has been proven that different adjuncts may be added to LA solutions to boost their effectiveness and longevity while lowering the overall dose of LA utilised and minimising any systemic side effects. Our goal was to assess the effectiveness of adjuvants such as dexmedetomidine and clonidine in comparison to 0.5% ropivacaine in an infraclavicular block for upper limb surgery under USG guidance. Method: Fifty adult patients planned for elective upperlimb surgery with an infraclavicular brachial plexus block under USG guidance were included. A...

Research paper thumbnail of Post-operative analgesic efficacy of fentanyl via different routes – A comparative study of nebulisation , intranasal and intravenous routes

Background: Pain is main post operative adverse outcomes causing patient distress, prolonging hos... more Background: Pain is main post operative adverse outcomes causing patient distress, prolonging hospital stay, and increasing the incidence of admissions after surgery. Study was done to assess and compare the post-operative analgesic effects of fentanyl via nebulisation, intranasal and intravenous routes to provide better analgesia, anxiolysis and sedation to the patient. Materials and methods: After approval from ethical committee of SPMC, Bikaner and written informed valid consent from patients, sixty patients of either sex belonging to ASA class I and II, were randomised into three group (Group I Nebulised Fentanyl, Group II Intranasal Fentanyl, Group III Intravenous Fentanyl). With all aseptic precaution, subarachnoid block was instilated via 23/25 gauze spinal needle by injecting sufficient dose of bupivacaine heavy 5% to achieve an adequate sensory and motor block for the proposed surgery. When patient complained pain 1 st time, fentanyl was given via nebulisation in group I, i...

Research paper thumbnail of To Compare the Effect of Dexmedetomidine and Clonidine as Adjuvant to Ropivacaine in Supraclavicular Brachial Plexus Block for Upper Limb Surgery

Background and Aim: Alpha-2 agonists as adjuvant to local anaesthetic agents for PNB enhance the ... more Background and Aim: Alpha-2 agonists as adjuvant to local anaesthetic agents for PNB enhance the quality and duration of analgesia. Aim of this prospective, double blind, randomised placebo controlled study was to compare the affect addition of Dexmedetomidine and clonidine to Ropivacaine with respect to onset, peak, and duration of sensory-motor block and duration of analgesia in Supraclavicular brachial plexus block. Materials and methods: Ninety ASA grade I or II patients of either sex, aged 18-60 years age scheduled for elective upper limb surgery were equally divided in three groups (n=30).Group R received 0.75% Ropivacaine 30 ml + 1ml NS, Group RC received 0.75% Ropivacaine 30ml +1μgm/kg of clonidine, Group RD received 0.75% Ropivacaine 30ml + 1μgm/kg of Dexmedetomidine in Supraclavicular plexus block by using nerve locator. Ashish Kumar Narolia, Kanta Bhati, Kuldeep Saini, Anita Pareek, Meera Kumari. To Compare the Effect of Dexmedetomidine and Clonidine as Adjuvant to Ropiva...

Research paper thumbnail of Comparison of conventional dose and low dose infusion of dexmedetomidine on hemodynamic stress response, dose of induction agent and postoperative analgesia in patients undergoing laparoscopic cholecystectomy

Background and Aim: Anesthetic techniques are based on hemodynamic stability during anesthesia an... more Background and Aim: Anesthetic techniques are based on hemodynamic stability during anesthesia and surgery. Dexmedetomidine is centrally acting α2 agonist with sedative, sympatholytic and analgesic. Aim of this study was to compare effect of conventional dose with low dose infusion of dexmedetomidine on hemodynamic stress response, induction agent requirement & postoperative analgesia. Materials and methods: Single randomised prospective study done on 100 ASA Ι and ΙΙ patients aged 18-65 years scheduled for elective laparoscopy cholecystectomy under general anesthesia. Patients were divided in to two groups of 50 each, Group A: 1 μg/kg loading dose of Rolaniya SL, Dhawan S, Meera Kumari, Jain R, Pareek A, Sehtia S. Comparison of conventional dose and low dose infusion of dexmedetomidine on hemodynamic stress response, dose of induction agent and postoperative analgesia in patients undergoing laparoscopic cholecystectomy. IAIM, 2017; 4(7): 111-117. Page 112 dexmedetomidine I.V. start...

Research paper thumbnail of A Comparative Evaluation of Dexmedetomidine, Propofol and Midazolam for Intraoperative Sedation in Regional Anaesthesia

Journal of Evolution of Medical and Dental Sciences, 2017

Research paper thumbnail of A Comparative Study of Dexmedetomidine and Clonidine as Premedicant on Intraocular Pressure and Haemodynamic Changes in Non-Ophthalmic Surgeries

Journal of Evolution of Medical and Dental Sciences, 2016

Research paper thumbnail of Fractionated dose versus bolus dose of isobaric injection ropivacaine (0.75%) for patients undergoing elective caesarean section under spinal anaesthesia: A randomized, double-blind study

Journal of applied pharmaceutical research, Aug 30, 2023

Background: Spinal anaesthesia (SA) using a bolus dose of Ropivacaine (0.75%) is known for its ra... more Background: Spinal anaesthesia (SA) using a bolus dose of Ropivacaine (0.75%) is known for its rapid onset but potential chances of hypotension. Administering Ropivacaine (0.75%) in fractions with intervals between the doses, has shown to establish a dense block, prolong analgesia and maintain better hemodynamic stability. This study aimed to compare the efficacy of fractionated and bolus doses of Ropivacaine (0.75%) in patients undergoing elective lower segment caesarean section (LSCS) under spinal anaesthesia. Methods: In a randomized, double-blinded trial, sixty patients scheduled for elective LSCS were enrolled and assigned to two groups. Group A received a single bolus spinal anaesthesia using Ropivacaine (0.75%) (2.5ml), while Group B received a fractionated dose approach: two-thirds of the total Ropivacaine (0.75%) dose (1.6ml) initially, followed by one-third dose (0.9ml) after 90 seconds. Results: The onset of sensory block (Group A: 3.59±1.31 min, Group B: 4.25±0.63 min) and motor block (Group A: 5.49±2.30 min, Group B: 7.34±11.28 min), as well as the duration of analgesia, were significantly longer in Group B (233.33±16.47 min) compared to Group A (185.17±20.61 min) (P<0.05). Hemodynamic stability was superior in Group B, with all patients showing better stability than those in Group A. Conclusion: Utilizing a fractionated dose of Ropivacaine (0.75%) in spinal anaesthesia results in an extended duration of analgesia and improved hemodynamic stability compared to a bolus dose approach.