Antoine Lesuffleur - Academia.edu (original) (raw)

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Papers by Antoine Lesuffleur

Research paper thumbnail of Plasmonic nanohole arrays for label-free kinetic biosensing in a lipid membrane environment

2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2009

We integrate periodic nanohole arrays in a thin gold film with lipid membranes in a microfluidic ... more We integrate periodic nanohole arrays in a thin gold film with lipid membranes in a microfluidic channel. Surface plasmon-enhanced light transmission through the periodic nanohole arrays enables real-time label-free sensing of molecular binding on the lipid membrane surface. This membrane biosensor can potentially act as a natural platform for studying binding kinetics of proteins with their binding partners anchored in the lipid membrane. We also present the concept of using nanopore arrays for kinetic assays of transmembrane proteins in a free-standing lipid membrane.

Research paper thumbnail of Plasmonic nanohole arrays for label-free kinetic biosensing in a lipid membrane environment

2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2009

We integrate periodic nanohole arrays in a thin gold film with lipid membranes in a microfluidic ... more We integrate periodic nanohole arrays in a thin gold film with lipid membranes in a microfluidic channel. Surface plasmon-enhanced light transmission through the periodic nanohole arrays enables real-time label-free sensing of molecular binding on the lipid membrane surface. This membrane biosensor can potentially act as a natural platform for studying binding kinetics of proteins with their binding partners anchored in the lipid membrane. We also present the concept of using nanopore arrays for kinetic assays of transmembrane proteins in a free-standing lipid membrane.

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