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Revista Española de Salud Pública, 2011
Fundamentos. Las pandemias requieren una valoracin de su nivel de gravedad. El objetivo fue deter... more Fundamentos. Las pandemias requieren una valoracin de su nivel de gravedad. El objetivo fue determinar las caracter sticas de la gripe pand mica en Catalu a. Métodos. Se reali un estudio de vigilancia sobre la incidencia de s ndromes gripales y casos graves entre junio del 2009 y mayo del 2010. Una red de 55 m dicos notificaron los s ndromes gripales y recogieron frotis nasofar ngeos. La gravedad de la pandemia se valor a trav s de casos graves confirmados. Se calcularon la letalidad y las tasas de incidencia y de mortalidad. La existencia de diferencias se estudi con el Riesgo Relativo (RR) y su intervalo de confian a (IC) del 95%. Resultados: La incidencia de s ndromes gripales fue muy superior en el grupo de 5 a 14 y de 0 a 4 a os (1227,8 y 1048,4 respectivamente, en la semana de m xima incidencia). De las muestras positivas 477 (52,4%) fueron positivas a virus gripal y la mayor a, 456 (95,6%) lo fueron al virus gripal pand mico A (H1N1) 2009. La incidencia de casos graves fue de...
Abstract: Many studies conducted during the last decade suggest the mental health benefits of gre... more Abstract: Many studies conducted during the last decade suggest the mental health benefits of green and blue spaces. We aimed to systematically review the available literature on the long-term mental health benefits of residential green and blue spaces by including studies that used standardized tools or objective measures of both the exposures and the outcomes of interest. We followed the PRISMA statement guidelines for reporting systematic reviews and meta-analysis. In total 28 studies were included in the systematic review. We found limited evidence for a causal relationship between surrounding greenness and mental health in adults, whereas the evidence was inadequate in children. The evidence was also inadequate for the other exposures evaluated (access to green spaces, quality of green spaces, and blue spaces) in both adults and children. The main limitation was the limited number of studies, together with the heterogeneity regarding
Gaceta Sanitaria, 2000
s una satisfacción para Gaceta Sanitaria poder acoger, un año más, los resúmenes de las comunicac... more s una satisfacción para Gaceta Sanitaria poder acoger, un año más, los resúmenes de las comunicaciones de la Reunión Anual de la SEE en el presente suplemento, cuyos contenidos también son accesibles en su integridad en la página web de la revista (www.masson.es/gs), de manera complementaria a los de las reuniones de otras sociedades afiliadas a SESPAS que han tenido lugar en los dos últimos años. En esta ocasión, ello reviste una especial connotación, puesto que resulta de un acuerdo recientemente suscrito entre la SEE, SESPAS y Editorial Doyma para la publicación de los resúmenes de la Reunión Anual de SEE en Gaceta Sanitaria por un período de cuatro años. En nombre del equipo editorial, debo agradecer a la Junta directiva de la SEE y a los patrocinadores que prestan su apoyo esta nueva prueba de confianza y este estímulo a nuestro compromiso editorial para con la difusión de las aportaciones de la investigación y la práctica epidemiológicas.
Contributions to science, 2012
El 2001, el Banc Mundial va assenyalar que el problema mes gran que la humanitat afrontaria en el... more El 2001, el Banc Mundial va assenyalar que el problema mes gran que la humanitat afrontaria en el segle XXI seria la pobresa. Avui dia sabem que 1.200 milions de persones, aproximadament una cinquena part de la poblacio mundial, viuen amb menys d'un dolar al dia i que les malalties transmissibles continuen representant la meitat de les morts i gairebe dos tercos dels anys de vida ajustats per discapacitat (AVADs) entre el 20 % mes pobre de la poblacio mundial. Des d'una perspectiva de salut global, es tracta d'una bretxa d'equitat en salut inacceptable. Si els medicaments i les mesures preventives existents fossin mes accessibles, ara mateix podrien salvar milions de vides. Alhora, la investigacio de nous medicaments i vacunes, i llur desenvolupament clinic posterior, son essencials per a obtenir municio eficac contra les malalties que mantenen les persones en situacio de pobresa. A la vista d'aquests reptes per la salut global, cal que els potencials beneficis d...
Gaceta sanitaria, 2005
OBJECTIVES To investigate the effectiveness of brief interventions to reduce alcohol intake in tr... more OBJECTIVES To investigate the effectiveness of brief interventions to reduce alcohol intake in traffic casualties with a positive blood alcohol concentration. METHODS Nine hundred forty-eight eligible casualties (97.6% of eligible casualties within a universe of 1106) were screened for alcohol and 126 (13.3%) were identified as positive. Interventions were performed in 85, randomly allocated to a minimal intervention (simple advice) or a brief intervention (motivational intervention). Telephone follow-up was scheduled for months 3, 6 and 12. The present study reports the results of follow-up at month 3. RESULTS Fifty-seven patients (67%) were followed up at month 3. A total of 73.7% had reduced their alcohol intake and this percentage was greater in the group who underwent the brief intervention (p = 0.06; effect size 0.5) and among heavy drinkers (p < 0.05). CONCLUSIONS The data indicate the effectiveness of the brief intervention, although the sample size does not allow definit...
BACKGROUND AND OBJECTIVE The aim of this study was to conduct an investigation into an outbreak o... more BACKGROUND AND OBJECTIVE The aim of this study was to conduct an investigation into an outbreak of gastroenteritis among health workers and residents (with different grades of dependence) at a nursing home. PATIENTS AND METHOD We detected an outbreak of gastroenteritis in a group of 52 health workers and 124 residents at a nursing home in Oliana, Lleida (Spain). A bidirectional prospective and retrospective cohort study was conducted into the consumption of water, food, grade of dependence (high, medium and low), and specific job. We studied the water supply and six food items. Faecal specimens from 30 patients were cultured and examined for Norovirus by polymerase chain reaction-reverse transcription. The possible implication of different factors associated with gastroenteritis was assessed by relative risk (RR) at 95% confidence intervals (CI). RESULTS We interviewed 97% of the patients (172/176). The overall attack rate was 53.3% (92/172). The symptoms were: diarrhoea 68.5% (63/9...
Orphanet Journal of Rare Diseases
Introduction In the current mobility and globalization context, there is a growing need to identi... more Introduction In the current mobility and globalization context, there is a growing need to identify potential changes on the pattern of diseases in the European Union (EU)/European Economic Area (EEA) and provide accurate diagnosis and treatment for the population. The pattern of rare communicable diseases that can affect people returning to EU/EEA from travel abroad, visiting EU/EEA or establishing in the EU/EEA is of special relevance. The objective of this manuscript is to give an overview about the EURaDMoG study and discuss the feasibility of establishing a European network on rare communicable diseases and other rare conditions linked to mobility and globalization. Methods We undertook a three-steps process where we first conducted a narrative review to estimate the prevalence and incidence and to list rare communicable and non-communicable diseases linked to mobility and globalization in the EU/EEA; second, we organized an international consultation workshop with experts in t...
Health Research Policy and Systems
Background The Health Product Profile Directory (HPPD) is an online database describing 8–10 key ... more Background The Health Product Profile Directory (HPPD) is an online database describing 8–10 key characteristics (such as target population, measures of efficacy and dosage) of product profiles for medicines, vaccines, diagnostics and other products that are intended to be accessed by populations in low- and middle-income countries. The HPPD was developed by TDR on behalf of WHO and launched on 15 May 2019. Methods The contents of the HPPD were downloaded into an Excel™ spreadsheet via the open access interface and analysed to identify the number of health product profiles by type, disease, year of publication, status, author organization and safety information. Results The HPPD contains summaries of 215 health product profiles published between 2008 and May 2019, 117 (54%) of which provide a hyperlink to the detailed publication from which the summary was extracted, and the remaining 98 provide an email contact for further information. A total of 55 target disease or health conditi...
Eurosurveillance
A, working group for developing the Catalonian Screening Programme for congenital transmission of... more A, working group for developing the Catalonian Screening Programme for congenital transmission of Chagas disease. The current screening programme for congenital transmission of Chagas disease in Catalonia, Spain.
Tubercle and Lung Disease, 1994
An ELISA-based serodiagnostic test for the rapid diagnosis of Mycobacterium tuberculosis (TB) inf... more An ELISA-based serodiagnostic test for the rapid diagnosis of Mycobacterium tuberculosis (TB) infections in humans has been developed. A synthetic, structural analogue of natural cord factor, a major component of the mycobacterial cell wall, was used as an antigen to coat microtitre plates. The levels of anti-natural cord factor Immunoglobulins M (IgM) and G (IgG) antibodies in diluted sera were measured using a horseradish peroxidase / Tetramethyl Benzidine (TMB) enzyme-substrate detector system. From a study conducted in Mexico (50 healthy controls, 50 patients with bacteriologically confirmed TB and 50 patients with pulmonary diseases other than TB), preliminary analysis of results has demonstrated increased anti-cord factor IgG antibodies but not IgM antibodies in patients with active TB infections. The sensitivity and specificity of this ELISA test, compared to sputum culture results, were found to be greater than 90%. It can be concluded from this study in Mexico that measurement of IgG antibodies using this pseudo cord-factor like glycolipid antigen provides a rapid and sensitive method for the serodiagnosis of tuberculosis. This ELISA test will be further evaluated in centres in Canada, U.S.A., Mexico and China.
Gaceta Sanitaria, Apr 1, 2009
Gaceta Sanitaria, Aug 1, 2002
Revista Española de Salud Pública, 2011
Fundamentos. Las pandemias requieren una valoracin de su nivel de gravedad. El objetivo fue deter... more Fundamentos. Las pandemias requieren una valoracin de su nivel de gravedad. El objetivo fue determinar las caracter sticas de la gripe pand mica en Catalu a. Métodos. Se reali un estudio de vigilancia sobre la incidencia de s ndromes gripales y casos graves entre junio del 2009 y mayo del 2010. Una red de 55 m dicos notificaron los s ndromes gripales y recogieron frotis nasofar ngeos. La gravedad de la pandemia se valor a trav s de casos graves confirmados. Se calcularon la letalidad y las tasas de incidencia y de mortalidad. La existencia de diferencias se estudi con el Riesgo Relativo (RR) y su intervalo de confian a (IC) del 95%. Resultados: La incidencia de s ndromes gripales fue muy superior en el grupo de 5 a 14 y de 0 a 4 a os (1227,8 y 1048,4 respectivamente, en la semana de m xima incidencia). De las muestras positivas 477 (52,4%) fueron positivas a virus gripal y la mayor a, 456 (95,6%) lo fueron al virus gripal pand mico A (H1N1) 2009. La incidencia de casos graves fue de...
Abstract: Many studies conducted during the last decade suggest the mental health benefits of gre... more Abstract: Many studies conducted during the last decade suggest the mental health benefits of green and blue spaces. We aimed to systematically review the available literature on the long-term mental health benefits of residential green and blue spaces by including studies that used standardized tools or objective measures of both the exposures and the outcomes of interest. We followed the PRISMA statement guidelines for reporting systematic reviews and meta-analysis. In total 28 studies were included in the systematic review. We found limited evidence for a causal relationship between surrounding greenness and mental health in adults, whereas the evidence was inadequate in children. The evidence was also inadequate for the other exposures evaluated (access to green spaces, quality of green spaces, and blue spaces) in both adults and children. The main limitation was the limited number of studies, together with the heterogeneity regarding
Gaceta Sanitaria, 2000
s una satisfacción para Gaceta Sanitaria poder acoger, un año más, los resúmenes de las comunicac... more s una satisfacción para Gaceta Sanitaria poder acoger, un año más, los resúmenes de las comunicaciones de la Reunión Anual de la SEE en el presente suplemento, cuyos contenidos también son accesibles en su integridad en la página web de la revista (www.masson.es/gs), de manera complementaria a los de las reuniones de otras sociedades afiliadas a SESPAS que han tenido lugar en los dos últimos años. En esta ocasión, ello reviste una especial connotación, puesto que resulta de un acuerdo recientemente suscrito entre la SEE, SESPAS y Editorial Doyma para la publicación de los resúmenes de la Reunión Anual de SEE en Gaceta Sanitaria por un período de cuatro años. En nombre del equipo editorial, debo agradecer a la Junta directiva de la SEE y a los patrocinadores que prestan su apoyo esta nueva prueba de confianza y este estímulo a nuestro compromiso editorial para con la difusión de las aportaciones de la investigación y la práctica epidemiológicas.
Contributions to science, 2012
El 2001, el Banc Mundial va assenyalar que el problema mes gran que la humanitat afrontaria en el... more El 2001, el Banc Mundial va assenyalar que el problema mes gran que la humanitat afrontaria en el segle XXI seria la pobresa. Avui dia sabem que 1.200 milions de persones, aproximadament una cinquena part de la poblacio mundial, viuen amb menys d'un dolar al dia i que les malalties transmissibles continuen representant la meitat de les morts i gairebe dos tercos dels anys de vida ajustats per discapacitat (AVADs) entre el 20 % mes pobre de la poblacio mundial. Des d'una perspectiva de salut global, es tracta d'una bretxa d'equitat en salut inacceptable. Si els medicaments i les mesures preventives existents fossin mes accessibles, ara mateix podrien salvar milions de vides. Alhora, la investigacio de nous medicaments i vacunes, i llur desenvolupament clinic posterior, son essencials per a obtenir municio eficac contra les malalties que mantenen les persones en situacio de pobresa. A la vista d'aquests reptes per la salut global, cal que els potencials beneficis d...
Gaceta sanitaria, 2005
OBJECTIVES To investigate the effectiveness of brief interventions to reduce alcohol intake in tr... more OBJECTIVES To investigate the effectiveness of brief interventions to reduce alcohol intake in traffic casualties with a positive blood alcohol concentration. METHODS Nine hundred forty-eight eligible casualties (97.6% of eligible casualties within a universe of 1106) were screened for alcohol and 126 (13.3%) were identified as positive. Interventions were performed in 85, randomly allocated to a minimal intervention (simple advice) or a brief intervention (motivational intervention). Telephone follow-up was scheduled for months 3, 6 and 12. The present study reports the results of follow-up at month 3. RESULTS Fifty-seven patients (67%) were followed up at month 3. A total of 73.7% had reduced their alcohol intake and this percentage was greater in the group who underwent the brief intervention (p = 0.06; effect size 0.5) and among heavy drinkers (p < 0.05). CONCLUSIONS The data indicate the effectiveness of the brief intervention, although the sample size does not allow definit...
BACKGROUND AND OBJECTIVE The aim of this study was to conduct an investigation into an outbreak o... more BACKGROUND AND OBJECTIVE The aim of this study was to conduct an investigation into an outbreak of gastroenteritis among health workers and residents (with different grades of dependence) at a nursing home. PATIENTS AND METHOD We detected an outbreak of gastroenteritis in a group of 52 health workers and 124 residents at a nursing home in Oliana, Lleida (Spain). A bidirectional prospective and retrospective cohort study was conducted into the consumption of water, food, grade of dependence (high, medium and low), and specific job. We studied the water supply and six food items. Faecal specimens from 30 patients were cultured and examined for Norovirus by polymerase chain reaction-reverse transcription. The possible implication of different factors associated with gastroenteritis was assessed by relative risk (RR) at 95% confidence intervals (CI). RESULTS We interviewed 97% of the patients (172/176). The overall attack rate was 53.3% (92/172). The symptoms were: diarrhoea 68.5% (63/9...
Orphanet Journal of Rare Diseases
Introduction In the current mobility and globalization context, there is a growing need to identi... more Introduction In the current mobility and globalization context, there is a growing need to identify potential changes on the pattern of diseases in the European Union (EU)/European Economic Area (EEA) and provide accurate diagnosis and treatment for the population. The pattern of rare communicable diseases that can affect people returning to EU/EEA from travel abroad, visiting EU/EEA or establishing in the EU/EEA is of special relevance. The objective of this manuscript is to give an overview about the EURaDMoG study and discuss the feasibility of establishing a European network on rare communicable diseases and other rare conditions linked to mobility and globalization. Methods We undertook a three-steps process where we first conducted a narrative review to estimate the prevalence and incidence and to list rare communicable and non-communicable diseases linked to mobility and globalization in the EU/EEA; second, we organized an international consultation workshop with experts in t...
Health Research Policy and Systems
Background The Health Product Profile Directory (HPPD) is an online database describing 8–10 key ... more Background The Health Product Profile Directory (HPPD) is an online database describing 8–10 key characteristics (such as target population, measures of efficacy and dosage) of product profiles for medicines, vaccines, diagnostics and other products that are intended to be accessed by populations in low- and middle-income countries. The HPPD was developed by TDR on behalf of WHO and launched on 15 May 2019. Methods The contents of the HPPD were downloaded into an Excel™ spreadsheet via the open access interface and analysed to identify the number of health product profiles by type, disease, year of publication, status, author organization and safety information. Results The HPPD contains summaries of 215 health product profiles published between 2008 and May 2019, 117 (54%) of which provide a hyperlink to the detailed publication from which the summary was extracted, and the remaining 98 provide an email contact for further information. A total of 55 target disease or health conditi...
Eurosurveillance
A, working group for developing the Catalonian Screening Programme for congenital transmission of... more A, working group for developing the Catalonian Screening Programme for congenital transmission of Chagas disease. The current screening programme for congenital transmission of Chagas disease in Catalonia, Spain.
Tubercle and Lung Disease, 1994
An ELISA-based serodiagnostic test for the rapid diagnosis of Mycobacterium tuberculosis (TB) inf... more An ELISA-based serodiagnostic test for the rapid diagnosis of Mycobacterium tuberculosis (TB) infections in humans has been developed. A synthetic, structural analogue of natural cord factor, a major component of the mycobacterial cell wall, was used as an antigen to coat microtitre plates. The levels of anti-natural cord factor Immunoglobulins M (IgM) and G (IgG) antibodies in diluted sera were measured using a horseradish peroxidase / Tetramethyl Benzidine (TMB) enzyme-substrate detector system. From a study conducted in Mexico (50 healthy controls, 50 patients with bacteriologically confirmed TB and 50 patients with pulmonary diseases other than TB), preliminary analysis of results has demonstrated increased anti-cord factor IgG antibodies but not IgM antibodies in patients with active TB infections. The sensitivity and specificity of this ELISA test, compared to sputum culture results, were found to be greater than 90%. It can be concluded from this study in Mexico that measurement of IgG antibodies using this pseudo cord-factor like glycolipid antigen provides a rapid and sensitive method for the serodiagnosis of tuberculosis. This ELISA test will be further evaluated in centres in Canada, U.S.A., Mexico and China.
Gaceta Sanitaria, Apr 1, 2009
Gaceta Sanitaria, Aug 1, 2002