Steffi Araujo - Academia.edu (original) (raw)

Papers by Steffi Araujo

Research paper thumbnail of Fatores de risco associados a obesidade em gatos

Brazilian Journal of Animal and Environmental Research

No mundo todo, a obesidade é reconhecida com uma condição de risco para saúde. Esta é caracteriza... more No mundo todo, a obesidade é reconhecida com uma condição de risco para saúde. Esta é caracterizada como uma condição de balanço energético positivo e excessiva formação de tecido adiposo com consequências diretas na qualidade de vida e bem estar dos animais. Neste trabalho foram utilizados 36 gatos obesos da rotina clínica do hospital veterinário Professor Sylvio Barbosa Cardoso, onde obteve-se desses animais prontuário clínico com histórico e anamnese, questionário respondido pelos tutores a respeito da rotina desses animais e exame físico completo. Este trabalho evidencia os principais fatores de risco que levam os gatos a desenvolverem a obesidade e comorbidades.

Research paper thumbnail of Veneno da Crotalus durissus: Efeitos biológicos e aplicações relevantes. Uma Revisão

Revista Brasileira de Higiene e Sanidade Animal, 2016

Research paper thumbnail of Ultrassonografia em gatos com doença renal crônica - Revisão de literatura

Revista Brasileira de Higiene e Sanidade Animal, 2020

Ultrassonografia em gatos com doença renal crônica-Revisão de literatura Ultrasonography in cats ... more Ultrassonografia em gatos com doença renal crônica-Revisão de literatura Ultrasonography in cats with chronic kidney disease-Literature review

Research paper thumbnail of Ultrassonografia em gatos com doença renal aguda – Uma Revisão de literatura

A Doenca Renal Aguda (DRA) em gatos e bastante recorrente na clinica de pequenos animais. O diagn... more A Doenca Renal Aguda (DRA) em gatos e bastante recorrente na clinica de pequenos animais. O diagnostico precoce e monitoramento dessa doenca e de suma importância, tendo em vista que sua presenca promovera o acumulo de toxinas uremicas, alem de provocar desequilibrio hidroeletrolitico e acido-basico no organismo. Para diagnosticar a DRA, o medico veterinario tera o auxilio de exames laboratoriais, tais como hemograma completo e bioquimico, e de tecnicas de diagnostico por imagem, dentre elas a ultrassonografia. O ultrassom na medicina veterinaria tem avancado de modo a possibilitar a realizacao de exames antes possiveis somente em pacientes humanos. O uso da ultrassonografia Doppler e contrastada contribui no acompanhamento de pacientes acometidos com doencas renais, tais como a DRA, atraves da observacao da dinâmica vascular nos rins, possibilitando assim a visualizacao da progressao da doenca nesses pacientes. Desse modo, essa revisao de literatura tem como intuito apresentar a ul...

Research paper thumbnail of Ultrasonography in cats with acute kidney disease - A literature review

Acute Kidney Disease (AKD) in cats is quite recurrent in the small animal clinic. Early diagnosis... more Acute Kidney Disease (AKD) in cats is quite recurrent in the small animal clinic. Early diagnosis and monitoring of this disease are important, given that its presence promotes or causes urinary toxins, in addition to causing hydroelectrolytic imbalance and basic acid in the body. In order to diagnose an AKD, the veterinarian will assist with laboratory tests, such as blood count, biochemical, in addition to imaging tests such as ultrasound examination. An ultrasound in veterinary medicine has advanced in order to allow exams to be carried out before only possible human patients. The use of ultrasonography in Doppler mode and ultrasound contrast with the monitoring of patients affected by kidney diseases, such as AKD, through the observation of vascular lesions in the kidneys, enabling the assessment of disease progression in these patients. In this way, literature review can present an ultrasound as an important diagnostic tool, addressing its aid in the identification of acute kid...

Research paper thumbnail of Acompanhamento clínico-laboratorial de obesidade associada ao hipotireoidismo em cão

Research paper thumbnail of Clinical-laboratory follow-up of obesity associated with hypothyroidism in a dog

Canine hypothyroidism is an endocrinopathy usually diagnosed in dogs. The main clinical signs pre... more Canine hypothyroidism is an endocrinopathy usually diagnosed in dogs. The main clinical signs present are metabolic (lethargy, weight gain and exercise intolerance) and dermatologic (dry, brittle hair coat, endocrine alopecia and myxedema). However, neuromuscular, cardiac, and reproductive changes may also be present. The diagnosis is accomplished by history, physical examination findings, clinicopathologic and measurement of hormones. The treatment of choice is levothyroxine sodium supplementation and treatment response is satisfactory with remission of clinical signs within 6 months of supplementation. This study aimed to report a case of hypothyroidism in a dog. A canine, mixed-breed, female, neutered, 4 years and weight 44.5 kg was forwarded to endocrinology assignment showing lethargy, weight gain, cold intolerance Ciência Animal, v.28, n.3, p.106-115, 2018. 107 and discrete hair rarefaction on the tail. At the complete blood count and serum biochemistry (ALT, GGT, AP, triglyce...

Research paper thumbnail of Caracterização Morfológica e Utilização da GGT urinária no diagnóstico da Lesão Renal Aguda em Gatos

Brazilian Journal of Development, 2020

Diante da prevalência da doença renal aguda em gatos com quadros obstrutivos e dos poucos estudos... more Diante da prevalência da doença renal aguda em gatos com quadros obstrutivos e dos poucos estudos com marcadores moleculares de lesão renal aguda o objetivo deste trabalho foi caracterizar as lesões renais e identificar a precocidade da lesão renal com gama glutamiltransferase urinária. Foram utilizados 20 gatos machos adultos, de diferentes raças, portadores de obstrução urinária causada por uma cistite idiopática felina diagnosticada clinicamente, por exames laboratoriais e de imagem além de um grupo controle de 10 gatos. Foi observado aumento dos valores de creatinina (p=0, 0068), ureia (p=0,0033) e relação proteína/creatinina urinária (p<0,05) comparado ao grupo controle. Os valores de GGTu não apresentaram diferenças estatísticas entre os grupos.

Research paper thumbnail of Doença Renal Aguda em gatos: conquistas e desafios

Medicina Veterinária (UFRPE), 2019

A doença renal aguda (DRA) refere-se a uma síndrome clínica associada a alta morbidade e mortalid... more A doença renal aguda (DRA) refere-se a uma síndrome clínica associada a alta morbidade e mortalidade, fazendo parte da síndrome de disfunção de múltiplos órgãos. Em medicina veterinária, estudos sobre a incidência de casos com DRA ainda são pouco elucidados, e a fisiopatologia da lesão renal aguda (LRA) é complexa, sendo caracterizada pela rápida diminuição da função excretora renal e consequente acúmulo de produtos do metabolismo de nitrogênio. Nesse contexto, o objetivo desse estudo foi apresentar a DRA com dados atuais sobre etiologia, patogenia, diagnóstico e tratamento.

Research paper thumbnail of Mast cell quantification in the skin of dogs with hormonal dermatosis

Medicina Veterinária (UFRPE), 2019

The mast cells are important in physiological and pathological skin events. They play an importan... more The mast cells are important in physiological and pathological skin events. They play an important role in the homeostatic regulatory mechanisms in the skin and thyroid gland. Mast cells present a barrier to difference external environmental stimuli and play a mediating role in the presence of infectious agents under the epidermis. This study aimed to quantify the number of mast cells in histological sections of the skin of healthy dogs and dogs with hypothyroidism and hyperadrenocorticism and to determine the distribution of mast cell numbers in the superficial dermis and deep dermis. When we compared the total mast cell count per high power field in dogs with hypothyroidism, hyperadrenocorticism and healthy dogs, only dogs with hypothyroidism had a significant difference in the quantification of mast cells per high power field, (p < 0.05). After analyzing our results, it was possible to conclude that animals with hypothyroidism produce greater amount of mast cells in the super...

Research paper thumbnail of Picrosirius Red and Masson’s Trichrome Staining Techniques as Tools for Detection of Collagen Fibers in the Skin of Dogs with Endocrine Dermatopathologies

Ciência Animal Brasileira, 2019

Canine endocrinopathies, such as hypothyroidism and hyperadrenocortism,induce typical dermatologi... more Canine endocrinopathies, such as hypothyroidism and hyperadrenocortism,induce typical dermatological alterations. Collagen fibers are significant for the maintenance of structural integrity,as well as in the determination of tissue function. This study aimed at assessing the coloration caused by Picrosirius Red staining under circular polarization and Masson Trichrome staining, as tools to quantify the total collagen in the skin of dogs exhibiting endocrine dermatopathies. Skin samples taken from dogs with hypothyroidism and hyperadrenocorticism were stained using Hematoxylin and Eosin (HE), Masson’s Trichrome (MT) and Picrosirius Red (PSR). The animals with hyperadrenocorticism revealed a higher percentage of collagen area than did the animals with hypothyroidism PSRp (hypothyroidism = 43.76 ± 0.8255 and hyperadrenocorticism = 47.08 ± 0.8584). The percentage of the collagen area using MT between the groups is given in parenthesis (hypothyroidism = 52.06 ± 0.9371, hyperadrenocortici...

Research paper thumbnail of Nutritional approach of pregnant queens and neonate cats: A review

Revista Brasileira de Higiene e Sanidade Animal, 2016

The knowledge about feline nutrition and its effects on the animal's health is a reality in veter... more The knowledge about feline nutrition and its effects on the animal's health is a reality in veterinary medicine. It has had progressively more investments in this area, since the dietary management can prevent the development of certain diseases affecting many organ systems and assists in the treatment of certain gastrointestinal diseases and others. The nutrition of cats has its defined importance because the feline diet has its differences according to the physiological stage of the animal and its nutritional requirements. It is understood that the nutritional variations are more evident between different physiological stages than even among different species at the same physiological stage. There are many differences in nutritional management in cats when compared to dogs. Since the concentration of proteins and lipids up to the amounts of vitamins and minerals that are necessary. To understand the nutritional needs of the feline species is essential to establish a balanced and healthy diet that can provide to the animal a higher life expectancy associated with a great quality of life. The aim of this study is to conduct a literature review on the most important aspects of nutrition in domestic cats, emphasizing the different physiological stages and their requirements for an adequate management of the dietary needs of these animals.

Research paper thumbnail of Dermatological manifestations associated with canine hypothyroidism: A review

Revista Brasileira de Higiene e Sanidade Animal, 2016

Canine endocrine dermatopathies account for 8.6% of the dermatological appointments, frequently p... more Canine endocrine dermatopathies account for 8.6% of the dermatological appointments, frequently presenting classic signs of non-pruritic bilaterally symmetrical alopecia that develops chronically. The most common are hypothyroidism, hyperadrenocorticism (HAC) and hyperestrogenism. Hypothyroidism is the most observed endocrine disease in dogs and it is characterized by a structural and / or functional abnormality in the gland, which leads to a deficient production of thyroid hormones. Clinical signs caused by insufficient thyroid hormones are commonly observed in the skin. Hormones produced by the thyroid are important in maintaining cutaneous function, once they perform a regulatory role in epidermal differentiation. Diagnosis of canine hypothyroidism is based on clinical and historical findings that are suggestive of the disease associated with supporting laboratory findings. The most frequently measured thyroid hormones are total tiroxine (TT4), total triiodothyronine (TT3) and free T4 (fT4). Skin biopsy may reveal histopathological findings highly suggestive of hypothyroidism such as vacuolization and arrector pili muscle hypertrophy. The combination of those knowledge is essential to the veterinarian when confronted with a chronic case of dermatological disorders, he or she may think about hypothyroidism as a possible diagnosis.

Research paper thumbnail of Crotalus durissus venom: biological effects and relevant applications. A Review

Revista Brasileira de Higiene e Sanidade Animal, 2016

Snakes have an important biological role in the ecological chain, as well as in scientific resear... more Snakes have an important biological role in the ecological chain, as well as in scientific researches performed with the venoms produced by them, since the enzyme-protein fractions these substances possess have been studied as pharmacological tools for the discovery of new therapies. Snakes of the genus Crotalus have gained significant relevance in the scientific field, since the venom produced by these reptiles has been the target of researchers in a few decades, due to the composition and the effects that these substances can produce. In Brazil, a single species represents the genus, which is Crotalus durissus. This review demonstrates that even with the advancement in scientific research on the composition, role and application of the venom produced by the subspecies of Crotalus durissus snake, it is necessary to further study their fractions and their action potential, which also demonstrates the how rich are these active components in different fields of biomedicine.

Research paper thumbnail of A clinical and diagnostic approach of a dog with hyperadrenocorticism and hypothyroidism related: Case report

Revista Brasileira de Higiene e Sanidade Animal, 2016

Dermatological diseases are the most frequent causes of veterinary appointments in the world. Hyp... more Dermatological diseases are the most frequent causes of veterinary appointments in the world. Hyperadrenocorticism is caused by the chronic excess of circulating endogenous or exogenous glucocorticoids, resulting in a set of physical and biochemical changes. Hypothyroidism is caused by imbalance in any part of the hypothalamic-pituitarythyroid axis. These endocrinopathies cause bilaterally symmetrical alopecia and other skin disorders. The aim of this study was a dog, male, Yorkshire breed, which the presence of chronic dermatological alterations was reported. In the physical examination, bilaterally symmetrical alopecia, bilateral otitis and pyoderma were observed. Complementary laboratory tests required were: microbiology, parasitology, serum biochemistry and histopathology of the skin. Among other findings, the histopathological findings showed alterations suggestive of hormonal Palavras-chaves: dermatose hormonal, histopatológico, endocrinopatias.

Research paper thumbnail of Fatores de risco associados a obesidade em gatos

Brazilian Journal of Animal and Environmental Research

No mundo todo, a obesidade é reconhecida com uma condição de risco para saúde. Esta é caracteriza... more No mundo todo, a obesidade é reconhecida com uma condição de risco para saúde. Esta é caracterizada como uma condição de balanço energético positivo e excessiva formação de tecido adiposo com consequências diretas na qualidade de vida e bem estar dos animais. Neste trabalho foram utilizados 36 gatos obesos da rotina clínica do hospital veterinário Professor Sylvio Barbosa Cardoso, onde obteve-se desses animais prontuário clínico com histórico e anamnese, questionário respondido pelos tutores a respeito da rotina desses animais e exame físico completo. Este trabalho evidencia os principais fatores de risco que levam os gatos a desenvolverem a obesidade e comorbidades.

Research paper thumbnail of Veneno da Crotalus durissus: Efeitos biológicos e aplicações relevantes. Uma Revisão

Revista Brasileira de Higiene e Sanidade Animal, 2016

Research paper thumbnail of Ultrassonografia em gatos com doença renal crônica - Revisão de literatura

Revista Brasileira de Higiene e Sanidade Animal, 2020

Ultrassonografia em gatos com doença renal crônica-Revisão de literatura Ultrasonography in cats ... more Ultrassonografia em gatos com doença renal crônica-Revisão de literatura Ultrasonography in cats with chronic kidney disease-Literature review

Research paper thumbnail of Ultrassonografia em gatos com doença renal aguda – Uma Revisão de literatura

A Doenca Renal Aguda (DRA) em gatos e bastante recorrente na clinica de pequenos animais. O diagn... more A Doenca Renal Aguda (DRA) em gatos e bastante recorrente na clinica de pequenos animais. O diagnostico precoce e monitoramento dessa doenca e de suma importância, tendo em vista que sua presenca promovera o acumulo de toxinas uremicas, alem de provocar desequilibrio hidroeletrolitico e acido-basico no organismo. Para diagnosticar a DRA, o medico veterinario tera o auxilio de exames laboratoriais, tais como hemograma completo e bioquimico, e de tecnicas de diagnostico por imagem, dentre elas a ultrassonografia. O ultrassom na medicina veterinaria tem avancado de modo a possibilitar a realizacao de exames antes possiveis somente em pacientes humanos. O uso da ultrassonografia Doppler e contrastada contribui no acompanhamento de pacientes acometidos com doencas renais, tais como a DRA, atraves da observacao da dinâmica vascular nos rins, possibilitando assim a visualizacao da progressao da doenca nesses pacientes. Desse modo, essa revisao de literatura tem como intuito apresentar a ul...

Research paper thumbnail of Ultrasonography in cats with acute kidney disease - A literature review

Acute Kidney Disease (AKD) in cats is quite recurrent in the small animal clinic. Early diagnosis... more Acute Kidney Disease (AKD) in cats is quite recurrent in the small animal clinic. Early diagnosis and monitoring of this disease are important, given that its presence promotes or causes urinary toxins, in addition to causing hydroelectrolytic imbalance and basic acid in the body. In order to diagnose an AKD, the veterinarian will assist with laboratory tests, such as blood count, biochemical, in addition to imaging tests such as ultrasound examination. An ultrasound in veterinary medicine has advanced in order to allow exams to be carried out before only possible human patients. The use of ultrasonography in Doppler mode and ultrasound contrast with the monitoring of patients affected by kidney diseases, such as AKD, through the observation of vascular lesions in the kidneys, enabling the assessment of disease progression in these patients. In this way, literature review can present an ultrasound as an important diagnostic tool, addressing its aid in the identification of acute kid...

Research paper thumbnail of Acompanhamento clínico-laboratorial de obesidade associada ao hipotireoidismo em cão

Research paper thumbnail of Clinical-laboratory follow-up of obesity associated with hypothyroidism in a dog

Canine hypothyroidism is an endocrinopathy usually diagnosed in dogs. The main clinical signs pre... more Canine hypothyroidism is an endocrinopathy usually diagnosed in dogs. The main clinical signs present are metabolic (lethargy, weight gain and exercise intolerance) and dermatologic (dry, brittle hair coat, endocrine alopecia and myxedema). However, neuromuscular, cardiac, and reproductive changes may also be present. The diagnosis is accomplished by history, physical examination findings, clinicopathologic and measurement of hormones. The treatment of choice is levothyroxine sodium supplementation and treatment response is satisfactory with remission of clinical signs within 6 months of supplementation. This study aimed to report a case of hypothyroidism in a dog. A canine, mixed-breed, female, neutered, 4 years and weight 44.5 kg was forwarded to endocrinology assignment showing lethargy, weight gain, cold intolerance Ciência Animal, v.28, n.3, p.106-115, 2018. 107 and discrete hair rarefaction on the tail. At the complete blood count and serum biochemistry (ALT, GGT, AP, triglyce...

Research paper thumbnail of Caracterização Morfológica e Utilização da GGT urinária no diagnóstico da Lesão Renal Aguda em Gatos

Brazilian Journal of Development, 2020

Diante da prevalência da doença renal aguda em gatos com quadros obstrutivos e dos poucos estudos... more Diante da prevalência da doença renal aguda em gatos com quadros obstrutivos e dos poucos estudos com marcadores moleculares de lesão renal aguda o objetivo deste trabalho foi caracterizar as lesões renais e identificar a precocidade da lesão renal com gama glutamiltransferase urinária. Foram utilizados 20 gatos machos adultos, de diferentes raças, portadores de obstrução urinária causada por uma cistite idiopática felina diagnosticada clinicamente, por exames laboratoriais e de imagem além de um grupo controle de 10 gatos. Foi observado aumento dos valores de creatinina (p=0, 0068), ureia (p=0,0033) e relação proteína/creatinina urinária (p<0,05) comparado ao grupo controle. Os valores de GGTu não apresentaram diferenças estatísticas entre os grupos.

Research paper thumbnail of Doença Renal Aguda em gatos: conquistas e desafios

Medicina Veterinária (UFRPE), 2019

A doença renal aguda (DRA) refere-se a uma síndrome clínica associada a alta morbidade e mortalid... more A doença renal aguda (DRA) refere-se a uma síndrome clínica associada a alta morbidade e mortalidade, fazendo parte da síndrome de disfunção de múltiplos órgãos. Em medicina veterinária, estudos sobre a incidência de casos com DRA ainda são pouco elucidados, e a fisiopatologia da lesão renal aguda (LRA) é complexa, sendo caracterizada pela rápida diminuição da função excretora renal e consequente acúmulo de produtos do metabolismo de nitrogênio. Nesse contexto, o objetivo desse estudo foi apresentar a DRA com dados atuais sobre etiologia, patogenia, diagnóstico e tratamento.

Research paper thumbnail of Mast cell quantification in the skin of dogs with hormonal dermatosis

Medicina Veterinária (UFRPE), 2019

The mast cells are important in physiological and pathological skin events. They play an importan... more The mast cells are important in physiological and pathological skin events. They play an important role in the homeostatic regulatory mechanisms in the skin and thyroid gland. Mast cells present a barrier to difference external environmental stimuli and play a mediating role in the presence of infectious agents under the epidermis. This study aimed to quantify the number of mast cells in histological sections of the skin of healthy dogs and dogs with hypothyroidism and hyperadrenocorticism and to determine the distribution of mast cell numbers in the superficial dermis and deep dermis. When we compared the total mast cell count per high power field in dogs with hypothyroidism, hyperadrenocorticism and healthy dogs, only dogs with hypothyroidism had a significant difference in the quantification of mast cells per high power field, (p < 0.05). After analyzing our results, it was possible to conclude that animals with hypothyroidism produce greater amount of mast cells in the super...

Research paper thumbnail of Picrosirius Red and Masson’s Trichrome Staining Techniques as Tools for Detection of Collagen Fibers in the Skin of Dogs with Endocrine Dermatopathologies

Ciência Animal Brasileira, 2019

Canine endocrinopathies, such as hypothyroidism and hyperadrenocortism,induce typical dermatologi... more Canine endocrinopathies, such as hypothyroidism and hyperadrenocortism,induce typical dermatological alterations. Collagen fibers are significant for the maintenance of structural integrity,as well as in the determination of tissue function. This study aimed at assessing the coloration caused by Picrosirius Red staining under circular polarization and Masson Trichrome staining, as tools to quantify the total collagen in the skin of dogs exhibiting endocrine dermatopathies. Skin samples taken from dogs with hypothyroidism and hyperadrenocorticism were stained using Hematoxylin and Eosin (HE), Masson’s Trichrome (MT) and Picrosirius Red (PSR). The animals with hyperadrenocorticism revealed a higher percentage of collagen area than did the animals with hypothyroidism PSRp (hypothyroidism = 43.76 ± 0.8255 and hyperadrenocorticism = 47.08 ± 0.8584). The percentage of the collagen area using MT between the groups is given in parenthesis (hypothyroidism = 52.06 ± 0.9371, hyperadrenocortici...

Research paper thumbnail of Nutritional approach of pregnant queens and neonate cats: A review

Revista Brasileira de Higiene e Sanidade Animal, 2016

The knowledge about feline nutrition and its effects on the animal's health is a reality in veter... more The knowledge about feline nutrition and its effects on the animal's health is a reality in veterinary medicine. It has had progressively more investments in this area, since the dietary management can prevent the development of certain diseases affecting many organ systems and assists in the treatment of certain gastrointestinal diseases and others. The nutrition of cats has its defined importance because the feline diet has its differences according to the physiological stage of the animal and its nutritional requirements. It is understood that the nutritional variations are more evident between different physiological stages than even among different species at the same physiological stage. There are many differences in nutritional management in cats when compared to dogs. Since the concentration of proteins and lipids up to the amounts of vitamins and minerals that are necessary. To understand the nutritional needs of the feline species is essential to establish a balanced and healthy diet that can provide to the animal a higher life expectancy associated with a great quality of life. The aim of this study is to conduct a literature review on the most important aspects of nutrition in domestic cats, emphasizing the different physiological stages and their requirements for an adequate management of the dietary needs of these animals.

Research paper thumbnail of Dermatological manifestations associated with canine hypothyroidism: A review

Revista Brasileira de Higiene e Sanidade Animal, 2016

Canine endocrine dermatopathies account for 8.6% of the dermatological appointments, frequently p... more Canine endocrine dermatopathies account for 8.6% of the dermatological appointments, frequently presenting classic signs of non-pruritic bilaterally symmetrical alopecia that develops chronically. The most common are hypothyroidism, hyperadrenocorticism (HAC) and hyperestrogenism. Hypothyroidism is the most observed endocrine disease in dogs and it is characterized by a structural and / or functional abnormality in the gland, which leads to a deficient production of thyroid hormones. Clinical signs caused by insufficient thyroid hormones are commonly observed in the skin. Hormones produced by the thyroid are important in maintaining cutaneous function, once they perform a regulatory role in epidermal differentiation. Diagnosis of canine hypothyroidism is based on clinical and historical findings that are suggestive of the disease associated with supporting laboratory findings. The most frequently measured thyroid hormones are total tiroxine (TT4), total triiodothyronine (TT3) and free T4 (fT4). Skin biopsy may reveal histopathological findings highly suggestive of hypothyroidism such as vacuolization and arrector pili muscle hypertrophy. The combination of those knowledge is essential to the veterinarian when confronted with a chronic case of dermatological disorders, he or she may think about hypothyroidism as a possible diagnosis.

Research paper thumbnail of Crotalus durissus venom: biological effects and relevant applications. A Review

Revista Brasileira de Higiene e Sanidade Animal, 2016

Snakes have an important biological role in the ecological chain, as well as in scientific resear... more Snakes have an important biological role in the ecological chain, as well as in scientific researches performed with the venoms produced by them, since the enzyme-protein fractions these substances possess have been studied as pharmacological tools for the discovery of new therapies. Snakes of the genus Crotalus have gained significant relevance in the scientific field, since the venom produced by these reptiles has been the target of researchers in a few decades, due to the composition and the effects that these substances can produce. In Brazil, a single species represents the genus, which is Crotalus durissus. This review demonstrates that even with the advancement in scientific research on the composition, role and application of the venom produced by the subspecies of Crotalus durissus snake, it is necessary to further study their fractions and their action potential, which also demonstrates the how rich are these active components in different fields of biomedicine.

Research paper thumbnail of A clinical and diagnostic approach of a dog with hyperadrenocorticism and hypothyroidism related: Case report

Revista Brasileira de Higiene e Sanidade Animal, 2016

Dermatological diseases are the most frequent causes of veterinary appointments in the world. Hyp... more Dermatological diseases are the most frequent causes of veterinary appointments in the world. Hyperadrenocorticism is caused by the chronic excess of circulating endogenous or exogenous glucocorticoids, resulting in a set of physical and biochemical changes. Hypothyroidism is caused by imbalance in any part of the hypothalamic-pituitarythyroid axis. These endocrinopathies cause bilaterally symmetrical alopecia and other skin disorders. The aim of this study was a dog, male, Yorkshire breed, which the presence of chronic dermatological alterations was reported. In the physical examination, bilaterally symmetrical alopecia, bilateral otitis and pyoderma were observed. Complementary laboratory tests required were: microbiology, parasitology, serum biochemistry and histopathology of the skin. Among other findings, the histopathological findings showed alterations suggestive of hormonal Palavras-chaves: dermatose hormonal, histopatológico, endocrinopatias.