Ariani Souza - Academia.edu (original) (raw)

Papers by Ariani Souza

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, Jan 21, 2018

To compare clinical and obstetric adverse events among pregnant women with sickle cell disease (S... more To compare clinical and obstetric adverse events among pregnant women with sickle cell disease (SCD) according to genotype. The present cross-sectional study enrolled women aged 15-49 years with SCD and prior pregnancy attending a hematology center in Recife, Brazil, between September 1, 2015, and April 30, 2016. Associations between sickle cell genotype (HbSS, HbSC, Sβ-thalassemia) and adverse events were evaluated. Overall, 89 women were included; 74 (83%) had HbSS genotype, 8 (9%) had HbSC genotype, and 7 (8%) had Sβ-thalassemia genotype. Fifty-three (60%) self-reported being of mixed race, and 27 (30%) self-reported they were black. Blood transfusion was observed more frequently among women with HbSS than among those with HbSC genotype (P=0.007). Postpartum adverse events were more frequent in the Sβ-thalassemia than in the HbSS group (P=0.030). Fetal intrauterine death occurred only among women with the HbSS genotype (11 [15%]). In the HbSS group, there was a higher frequency o...

Public health reports (Washington, D.C. : 1974), 2018

We assessed sociodemographic and health care factors of mothers and newborns during a 2015-2016 o... more We assessed sociodemographic and health care factors of mothers and newborns during a 2015-2016 outbreak of microcephaly in Recife, Brazil, and we analyzed the spatial distribution and incidence risk of newborns with microcephaly in relation to socio-environmental indicators. We collected data from August 2015 through May 2016 from Brazil's Live Birth Information System and Bulletin of Microcephaly Notification, and we geocoded the data by maternal residence. We constructed thematic maps of districts, according to socio-environmental and vector indicators. We identified spatial aggregates of newborns with microcephaly by using the Bernoulli model. We performed logistic regression analyses to compare the incidence risk of microcephaly within socio-environmental indicator groups. We geocoded 17 990 of 19 554 (92.0%) live births in Recife, of which 202 (1.1%) newborns were classified as having microcephaly, based on a head circumference of ≥2 standard deviations below the mean. Lar...

Revista Bioetica, May 24, 2012

Projeto acadêmico sem fins lucrativos desenvolvido no âmbito da iniciativa Acesso Aberto ƌƟŐŽƐ ĚĞ... more Projeto acadêmico sem fins lucrativos desenvolvido no âmbito da iniciativa Acesso Aberto ƌƟŐŽƐ ĚĞ ĂƚƵĂůŝǌĂĕĆŽ

Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, 1995

A study of pregnant women attending the prenatal clinic of the Instituto Materno Infantil de Pern... more A study of pregnant women attending the prenatal clinic of the Instituto Materno Infantil de Pernambuco in Recife Brazil found an unexpectedly low prevalence of human immunodeficiency virus (HIV) infection in this population. 20110 pregnant women were seen at this national reference center in 1993. Of the 1000 such women tested in July and August 1993 only one serum sample was reactive to both HIV-1 enzyme-linked immunosorbet assays and the confirmatory indirect immunofluorescence assay yielding an HIV-1 seroprevalence rate of 0.1% (95% confidence interval 0-0.3). Currently underway is a seroprevalence survey of nonpregnant heterosexual women in Recife. By the end of 1993 Pernambuco State had registered 1131 acquired immunodeficiency syndrome (AIDS) cases including 136 (12%) in women and 32 (2.8%) in children.

Journal of Clinical Virology, 2014

Background: Dengue affects nearly 400 million people annually worldwide and considered one of the... more Background: Dengue affects nearly 400 million people annually worldwide and considered one of the most serious health threats in tropical and subtropical countries. Objective: To analyze the occurrence of dengue infection among the parturient who have formed the baseline of an ongoing birth cohort study in the city of Recife, Northeast of Brazil. Study design: From March 2011 to May 2012, we recruited 417 parturients with low-risk pregnancies at maternity ward who agreed to a follow-up of their babies. Dengue infection was accessed through DENV RT-PCR and anti-dengue antibodies (IgM and IgG). The prevalence of IgG antibodies in the parturients and their concepts were determined. The concordance among the pairs was tested using Kappa. The association of recent infection (IgM and/or DENV RT-PCR positive) with the maternal characteristics and clinical features of the neonates was analyzed through logistic regression. Results: The prevalence of IgG antibodies in the maternal and cord blood samples was 95.1% (95% CI: 92.6-96.9%) and 95.8% (95% CI: 93.4-97.5%), respectively, with high agreement between maternal-cord pairs (Kappa = 0.93). The prevalence of recent infection was 10.6% (95% CI: 7.9-14.2%) in the parturients. Reported fever during pregnancy was associated to recent infection (p = 0.023). Conclusion: The data draw attention for the high frequency of anti-dengue antibodies in the women studied and for the high occurrence of infection during pregnancy in this region of Brazil. There is a need for further studies to better characterize dengue infection in pregnant women.

Contraception, 2011

Background: Brazilian women who have undergone abortion use contraceptive methods; however, their... more Background: Brazilian women who have undergone abortion use contraceptive methods; however, their use of contraceptive methods is inconsistent and/or inappropriate. Study Design: This randomized trial evaluated the effectiveness of a personalized counseling on contraceptive acceptability and its use for postabortion women in the northeast of Brazil. It was conducted in July 2008 to September 2009, enrolling 246 women randomly distributed in intervention (n=123) and control (n=123) groups. An intention-to-treat analysis was performed. Results: In the follow-up, 98.4% women in the intervention group were using contraceptive methods compared with 70.6% women in the control group (pb.001). The probability of adherence and of the use of any kind of contraceptive method 6 months after the abortion was 41% greater in the intervention group. Conclusions: The strategy on individualized contraceptive counseling increased the acceptance and the use of contraceptive methods and increased the adequate use of the methods.

Bulletin of Environmental Contamination and Toxicology, 2010

This ecological study analyzed the association between pesticide use and prematurity, low weight ... more This ecological study analyzed the association between pesticide use and prematurity, low weight and congenital abnormality at birth, infant death by congenital abnormality, and fetal death in Brazil in 2001. Simple linear regression analysis has determined a positive association between pesticide use and prematurity, low birth weight, and congenital abnormality. The association between pesticide use and low birth weight (p = 0.045) and, congenital abnormality (p = 0.004) and infant death rate by congenital abnormality (p = 0.039) remained after the adjustment made by the proportion of pregnant women with a low number of prenatal care visits.

... Titre du document / Document title. Right conclusion, wrong method: Drs Ferreira and Souza re... more ... Titre du document / Document title. Right conclusion, wrong method: Drs Ferreira and Souza reply to Dr Berger's letter. Auteur(s) / Author(s). CARNEIRO GOMES FERREIRAAna Laura ; IMPIERI DE SOUZA Ariani ; Revue / Journal Title. ...

BackgroundLike HPV types, different lineages also appear to have different carcinogenic capabilit... more BackgroundLike HPV types, different lineages also appear to have different carcinogenic capabilities. Studies have shown that oncogenic HPV specific to the genotype lineage is associated with different risks for the development of cervical intraepithelial neoplasia (CIN2 / CIN3) and cervical cancer. This study aims to analyze the genetic diversity of HPV 16 genotype in cases of cervical intraepithelial neoplasia (CIN2/CIN3) and cervical cancer in women from the Northeast region of Brazil.Methods and ResultsA cross-sectional hospital-based study conducted in the Northeast region of Brazil from 2014 through 2016. In the sample, there were 196 cases of HPV-16 variant (59 cervical intraepithelial neoplasia - CIN2/CIN3 and 137 cases of cervical cancer). Difference of proportion test was used to compare groups of CIN2/CIN3 and cervical cancer by viral lineage (p-value <0.05) in respect to HPV-16 lineage prevalence.The percentage of lineage frequencies by histopathological diagnosis sho...

Hematology, Transfusion and Cell Therapy, 2019

Background: Despite advances in health care for sickle cell disease patients, as well as in the i... more Background: Despite advances in health care for sickle cell disease patients, as well as in the improvement in reproductive issues mainly in women with the disease, pregnancy is still a challenge, both for the mother and the child, with high rates of maternal and fetal morbidity and mortality. Besides their chronic hemolytic status and vaso-occlusive events that confer systemic complications, pregnant women also have higher rates of pain episodes, infections, abortion, intrauterine growth retardation, pre-term births, eclampsia, stillbirth and the hemolysis, elevated liver enzymes and low platelets syndrome. The physiologic mechanisms of the disease in pregnancy are still unknown and chronic inflammatory responses may interfere in the adverse outcomes. The cytokine and chemokine profiles in pregnancy with sickle cell disease remain unknown. The aim of this study was to evaluate the cytokine profile of the inflammatory response of pregnant women with sickle cell disease. Method: Blood samples from 20 pregnant women with sickle cell disease, 24 women with sickle cell disease in steady state, 16 healthy pregnant women and a control group with 9 women at childbearing age were assayed for interleukin-6. Main results: Pregnant women with sickle cell disease presented high serum levels of interleukin-6, compared to healthy pregnant women (p = 0.0115). Conclusion: These data suggest that the increased production of interleukin-6 may occur during pregnancy with sickle cell disease and that the role of this cytokine in the sickle cell disease pathophysiology and pregnancy complications should be further studied.

Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia, Jan 6, 2017

Purpose To describe the reproductive variables associated with different sickle cell disease (SCD... more Purpose To describe the reproductive variables associated with different sickle cell disease (SCD) genotypes and the influence of contraceptive methods on acute painful episodes among the women with the homozygous hemoglobin S (HbSS) genotype. Methods A cross-sectional study was conducted between September of 2015 and April of 2016 on 158 women afflicted with SCD admitted to a hematology center in the Northeast of Brazil. The reproduction-associated variables of different SCD genotypes were assessed using the analysis of variance (ANOVA) test to compare means, and the Kruskal-Wallis test to compare medians. The association between the contraceptive method and the acute painful episodes was evaluated by the Chi-square test. Results The mean age of women with SCD was 28.3 years and 86.6% were mixed or of African-American ethnicity. With respect to the genotypes, 134 women (84.8%) had HbSS genotype, 12 women (7.6%) had hemoglobin SC (HbSC) disease genotype, and 12 (7.6%) were identifie...

Revista da Sociedade Brasileira de Medicina Tropical, 2016

Dengue infection has not been routinely investigated among pregnant women and parturients with ac... more Dengue infection has not been routinely investigated among pregnant women and parturients with acute febrile syndrome in endemic settings. Here, we report two cases of dengue fever detected at the time of delivery in parturients enrolled in a cohort prospective study conducted in a hospital in Recife, Brazil. The parturients reported fever onset within seven days prior to delivery, and dengue infection was confirmed upon detection of viral ribonucleic acid (RNA) by using the reverse transcriptasepolymerase chain reaction. Dengue infection should be considered as a diagnostic possibility in cases of fever during pregnancy and labor, especially in endemic areas.

Journal of Infectious Diseases, 2016

Background. Maternal-fetal transferred dengue virus (DENV)-specific antibodies have been implicat... more Background. Maternal-fetal transferred dengue virus (DENV)-specific antibodies have been implicated in the immunopathogenesis of dengue during infancy. Methods. A prospective birth cohort was established in a dengue-endemic area in the Northeast Region of Brazil. DENV-specific immunoglobulin G (IgG) and DENV-1-4 serotype-specific neutralizing antibody (NAb) levels were assessed in 376 paired maternal and umbilical cord blood samples. The kinetics of enhancing activity by maternally acquired DENV antibodies was determined in serum samples from children enrolled in the cohort. Results. Mothers were mostly immune to DENV-3 alone (53.7%) or combined with DENV-4 (30.6%). Levels of DENV-specific IgG, DENV-3 NAbs, and DENV-4 NAbs were significantly higher in newborns than in their respective mothers. Mothers immune to a single serotype transferred greater levels of DENV-specific IgG (P = .02) and DENV-3 NAbs (P = .04) than mothers immune to multiple DENV serotypes. Maternally acquired DENV-3 NAbs disappeared in >90% of the children by the age of 4 months. The peak enhancing activity was detected by the age of 2 months (P < .0001) and rapidly declined by the age of 4 months (P = .0035). Conclusions. Unlike Asian infants, the enhancing activity of DENV infection by maternally transferred DENV antibodies occurs at earlier ages in Brazilian children. These findings might explain the low occurrence of severe dengue among infants in our setting.

Open Journal of Obstetrics and Gynecology, 2015

Objectives: To estimate the contraceptive use rate, pregnancy and abortion rate two years after p... more Objectives: To estimate the contraceptive use rate, pregnancy and abortion rate two years after post abortion counselling. Methods: In this current paper we conducted a cross-sectional study from September to December 2011 among women who participated of original randomized trial. In this study 118 women who had been allocated in the group that received the personalized contraceptive counselling and 103 women who had been allocated in the group that received standard counselling service were contacted by phone. The analyzed variables were the use of contraceptive methods, reasons for not using them, satisfaction in used method, and occurrence of pregnancy and abortion. Results: The pregnancy rate was lower in the personalized counselling group (p = 0.022), whereas abortion (p = 0.543) and contraceptive use rate (p = 0.270) had no difference between groups. The overall contraceptive use rate was high in both groups and the injectable method use rate was higher in personalized counselling group (p = 0.004). Conclusions: Two years after the intervention the pregnancy rate was lower in personalized counselling group. The contraceptive use rate had no difference between the groups, except for the injectable which the use rate was higher in the personalized counselling group. These results could be encouraging because the intervention improved the uptake of one of the long-acting methods of contraception.

Revista da Escola de Enfermagem da USP, 2010

Estudo de corte transversal, realizado com 160 mulheres no período de 2005-2006, com o objetivo d... more Estudo de corte transversal, realizado com 160 mulheres no período de 2005-2006, com o objetivo de descrever as características sócio-demográficas e reprodutivas de mulheres hospitalizadas por abortamento e o conhecimento sobre métodos contraceptivos e de indução para o abortamento. Para determinação da associação entre a classificação do abortamento e as variáveis sócio-demográficas e reprodutivas, utilizou-se o teste qui-quadrado de Pearson, considerando-se o nível de significância de 5%. Observou-se uma frequência de 56,3% de abortamento possivelmente induzido. A maioria ocorreu antes das 12 semanas (55,7%). Em relação ao perfil das mulheres: 48,9% entre 20-29 anos, 72,0% com oito anos ou mais de estudo; 90,1% tinham companheiros; 52,0% tinham de 1-3 filhos, 100% conheciam a pílula e o preservativo, e 80,0% o misoprostol. O perfil sócio-demográfico e reprodutivo das mulheres hospitalizadas por abortamento no serviço não se alterou nos últimos anos. O método mais conhecido para in...

Revista Brasileira de Hematologia e Hemoterapia, 2011

Revista Brasileira de Ginecologia e Obstetrícia, 2007

Findings of gynecological laparoscopies in women with reproductive problems in a teaching hospita... more Findings of gynecological laparoscopies in women with reproductive problems in a teaching hospital: a case series Mari a da ConCei ção Fari as souto Mai or 1 ariani iMpieri de souza 2 Melânia Maria raMos de aMoriM 2 eManuelle pessa Valente 1 aurélio ribeiro Costa 1 adriana sCaVuzzi Carneiro da Cunha 1 José eulálio Cabral-Filho 2 Artigos originais Resumo ObjetivO: descrever as características das videolaparoscopias ginecológicas realizadas em pacientes com dificuldade reprodutiva atendidas em um hospital-escola no Recife, Pernambuco. MétOdOs: foi realizado um estudo descritivo, de base hospitalar, do tipo série de casos. As informações foram obtidas a partir dos relatórios cirúrgicos das videolaparoscopias realizadas no Instituto Materno Infantil Professor Fernando Figueira, em Recife, entre janeiro de 2000 e dezembro de 2004. O critério de inclusão foi infertilidade ou estudo pré-recanalização como indicação cirúrgica. Para análise, utilizou-se o programa estatístico Epi-Info 3.3.2. Criaram-se tabelas de medidas de tendência central e de dispersão para as variáveis quantitativas e distribuição de freqüência para as variáveis categóricas. ResultadOs: foram analisados 462 laudos de laparoscopias, dos quais 295 (63,8%) tiveram como indicação a infertilidade ou o estudo para recanalização tubária. A média de idade de ambos os grupos foi de 30 a 34 anos. Nos casos de infertilidade, os achados mais freqüentes foram aderências (60,6%), obstrução tubária (40,9%) e endometriose (36,1%). Nos casos de estudo da condição tubária pré-recanalização, das 87 pacientes analisadas, 55,2% apresentavam uma ou ambas as trompas inadequadas. Dentre estas, em 52,1% foi diagnosticada amputação tubária. Os procedimentos mais realizados foram adesiólise (34,2%), biópsias (21%), tratamento da endometriose (10,8%) e salpingostomia (8,1%). COnClusãO: a videolaparoscopia apresenta-se como importante instrumento na pesquisa e tratamento dos casos de dificuldade reprodutiva principalmente em serviços que não dispõem de técnicas avançadas de reprodução humana.

Reproductive Health, 2010

Background: In Brazil, a Ministry of Health report revealed women who underwent an abortion were ... more Background: In Brazil, a Ministry of Health report revealed women who underwent an abortion were predominantly in the use of contraceptive methods, but mentioned inconsistent or erroneously contraceptive use. Promoting the use of contraceptive methods to prevent unwanted pregnancies is one of the most effective strategies to reduce abortion rates and maternal morbidity and mortality. Therefore, providing post-abortion family planning services that include structured contraceptive counseling with free and easy access to contraceptive methods can be suitable. So the objective of this study is to determine the acceptance and selection of contraceptive methods followed by a postabortion family planning counseling. Methods: A cross-sectional study was carried out from July to October 2008, enrolling 150 low income women to receive post-abortion care at a family planning clinic in a public hospital located in Recife, Brazil. The subjects were invited to take part of the study before receiving hospital leave from five different public maternities. An appointment was made for them at a family planning clinic at IMIP from the 8 th to the 15 th day after they had undergone an abortion. Every woman received information on contraceptive methods, side effects and fertility. Counseling was individualized and addressed them about feelings, expectations and motivations regarding contraception as well as pregnancy intention. Results: Of all women enrolled in this study, 97.4% accepted at least one contraceptive method. Most of them (73.4%) had no previous abortion history. Forty of the women who had undergone a previous abortion, 47.5% reported undergoing unsafe abortion. Slightly more than half of the pregnancies (52%) were unwanted. All women had knowledge of the use of condoms, oral contraceptives and injectables. The most chosen method was injectables, followed by oral contraceptives and condoms. Only one woman chose an intrauterine device. Conclusion: The acceptance rate of post-abortion contraceptive methods was greater and the most chosen method was the best-known one. Implementing a specialized family planning post abortion service may promote an acceptance, regardless of the chosen method. Most important is they do receive contraception if they do not wish for an immediate pregnancy.

Journal of Tropical Pediatrics, 2011

Aim: To assess the knowledge of HIV/AIDS prevention and factors associated with condom use among ... more Aim: To assess the knowledge of HIV/AIDS prevention and factors associated with condom use among adolescent. Methods: A cross-sectional study was conducted among 410 outpatient adolescents. Association between knowledge on the transmission of HIV/AIDS and variables were analyzed using the chi-square test. Logistic regression model was used to estimate the factors associated to condom use. Results: The knowledge about HIV/AIDS transmission was high and lower percentages of knowledge were observed regarding the non-transmission of HIV/AIDS. Younger adolescents revealed less knowledge than older adolescents. After multiple logistic regression the following factors were associated with condom use: male gender (p ¼ 0.029), same age between partners (p ¼ 0.002) and having until 1 year elapsed since sexual initiation (p ¼ 0.001). Conclusion: The knowledge regarding HIV/AIDS prevention was satisfactory. However, this does not imply that adolescents put such knowledge to use.

Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics, 2019

Objective The main objective of the present study was to estimate the annual treatment costs of i... more Objective The main objective of the present study was to estimate the annual treatment costs of invasive cervical cancer (ICC) per patient at an oncology center in Brazil from a societal perspective by considering direct medical, direct nonmedical, and indirect costs. Methods A cost analysis descriptive study, in which direct medical, direct nonmedical, and indirect costs were collected using a microcosting approach, was conducted between May 2014 and July 2016 from a societal perspective. The study population consisted of women diagnosed with ICC admitted to a tertiary hospital in Recife, state of Pernambuco, Brazil. The annual cost per patient was estimated in terms of the value of American Dollars (US$) in 2016. Results From a societal perspective, the annual ICC treatment cost per patient was US$ 2,219.73. Direct medical costs were responsible for 81.2% of the total value, of which radiotherapy and outpatient chemotherapy had the largest share. Under the base-case assumption, th...