Arias Cedeño - Academia.edu (original) (raw)
Papers by Arias Cedeño
Related Article: H.Wachtler, D.P.Fuentes, D.Michalik, M.Kockerling, A.Villinger, U.Kragl, Q.A.Ced... more Related Article: H.Wachtler, D.P.Fuentes, D.Michalik, M.Kockerling, A.Villinger, U.Kragl, Q.A.Cedeno, C.Vogel|2011|Synthesis|2011|3099|doi:10.1055/s-0030-1260200
Revista Cubana de Química, Dec 1, 2017
In this work the antibacterial activity against Staphylococcus aureus resistant to methicillin wa... more In this work the antibacterial activity against Staphylococcus aureus resistant to methicillin was determined and the phytochemical composition of bioactive fractions was obtained from Cassia uniflora leaves. Eight fractions were prepared by column chromatography from the chloroform extract of the leaves, which were subjected to determinations of the antibacterial activity by the Bauer-Kirby method and the phytochemical composition by phytochemical screening, thin layer chromatography and UV and IR spectroscopies. Two fractions showed antibacterial activity against Staphylococcus aureus resistant to methicillin. Secondary metabolites associated with biological activity could be flavonoids and coumarins. UV and IR spectra and comparison of the IR spectrum of the most active fraction with a database with more than 100,000 compounds suggest that the active component may be a coumarin, specifically an aminocoumarin.
Luffa cylindrica L. Roem, propagated in Cuba in a wild way, commonly known as scouring pad has be... more Luffa cylindrica L. Roem, propagated in Cuba in a wild way, commonly known as scouring pad has been little researched and interesting medicinal properties are attributed to it. The objective of the work was to determine the in vitro antioxidant capacity of the ethanolic extracts of the fruit of this plant. The extracts were prepared by maceration in 70 % ethanol and the total antioxidant capacity determined by ultraviolet - visible spectrophotometry. The evaluated ethanolic extracts of the Luffa cylindrica L. fruit, both in the green and dry mature states, possess antioxidant activity. The phytochemical composition of the extracts was explored qualitatively by phytochemical screening and it was possible to detect the presence of triterpenes, polyphenols, anthocyanidins, and abundant coumarins in both extracts; as well as saponins and glycosides in the extract of the immature green fruit, metabolites that could be responsible for the antioxidant capacity shown.
Introduccion: Curcuma longa L. se comenzo a cultivar en Cuba en la decada de los noventa del pasa... more Introduccion: Curcuma longa L. se comenzo a cultivar en Cuba en la decada de los noventa del pasado siglo, a esta planta se le atribuyen propiedades anticancerigenas, antioxidantes, antibacterianas, entre otras. Su principio activo principal es la curcumina, un pigmento amarillo a partir del cual se pueden obtener diversos derivados de gran interes farmacologico. Objetivo: demostrar la factibilidad del uso de curcumina extraida de su fuente natural como precursor de farmacos. Metodos: los rizomas de Curcuma longa L. fueron previamente tratados; despues de estar secos, se pulverizaron y la extraccion se realizo con metanol en un bano ultrasonico. El producto deseado (curcumina) se purifico por cromatografia de columna, para ser usado posteriormente como la materia de partida en la obtencion de un analogo semisintetico. Los compuestos aislados y sintetizados se caracterizaron por metodos espectroscopicos. Resultados: se logro aislar curcumina con alto grado de pureza a partir de la Cu...
Synthesis, 2011
... Heike Wächtler a,b , Dilver Peña Fuentes a , Dirk Michalik c , Martin Köckerling a , Alexande... more ... Heike Wächtler a,b , Dilver Peña Fuentes a , Dirk Michalik c , Martin Köckerling a , Alexander Villinger a , Udo Kragl a , Quirino Arias Cedeño d , Christian Vogel* a. ... Reagents and conditions: (i) MsCl, Et 3 N, CH 2 Cl 2 , 20 min, 5 ˚C, and PTSCl, py,12 h, 5-20 ˚C; (ii) NaN 3 , 18 ...
Journal für Praktische Chemie/Chemiker-Zeitung, 1997
Related Article: H.Wachtler, D.P.Fuentes, D.Michalik, M.Kockerling, A.Villinger, U.Kragl, Q.A.Ced... more Related Article: H.Wachtler, D.P.Fuentes, D.Michalik, M.Kockerling, A.Villinger, U.Kragl, Q.A.Cedeno, C.Vogel|2011|Synthesis|2011|3099|doi:10.1055/s-0030-1260200
Revista Cubana de Química, Dec 1, 2017
In this work the antibacterial activity against Staphylococcus aureus resistant to methicillin wa... more In this work the antibacterial activity against Staphylococcus aureus resistant to methicillin was determined and the phytochemical composition of bioactive fractions was obtained from Cassia uniflora leaves. Eight fractions were prepared by column chromatography from the chloroform extract of the leaves, which were subjected to determinations of the antibacterial activity by the Bauer-Kirby method and the phytochemical composition by phytochemical screening, thin layer chromatography and UV and IR spectroscopies. Two fractions showed antibacterial activity against Staphylococcus aureus resistant to methicillin. Secondary metabolites associated with biological activity could be flavonoids and coumarins. UV and IR spectra and comparison of the IR spectrum of the most active fraction with a database with more than 100,000 compounds suggest that the active component may be a coumarin, specifically an aminocoumarin.
Luffa cylindrica L. Roem, propagated in Cuba in a wild way, commonly known as scouring pad has be... more Luffa cylindrica L. Roem, propagated in Cuba in a wild way, commonly known as scouring pad has been little researched and interesting medicinal properties are attributed to it. The objective of the work was to determine the in vitro antioxidant capacity of the ethanolic extracts of the fruit of this plant. The extracts were prepared by maceration in 70 % ethanol and the total antioxidant capacity determined by ultraviolet - visible spectrophotometry. The evaluated ethanolic extracts of the Luffa cylindrica L. fruit, both in the green and dry mature states, possess antioxidant activity. The phytochemical composition of the extracts was explored qualitatively by phytochemical screening and it was possible to detect the presence of triterpenes, polyphenols, anthocyanidins, and abundant coumarins in both extracts; as well as saponins and glycosides in the extract of the immature green fruit, metabolites that could be responsible for the antioxidant capacity shown.
Introduccion: Curcuma longa L. se comenzo a cultivar en Cuba en la decada de los noventa del pasa... more Introduccion: Curcuma longa L. se comenzo a cultivar en Cuba en la decada de los noventa del pasado siglo, a esta planta se le atribuyen propiedades anticancerigenas, antioxidantes, antibacterianas, entre otras. Su principio activo principal es la curcumina, un pigmento amarillo a partir del cual se pueden obtener diversos derivados de gran interes farmacologico. Objetivo: demostrar la factibilidad del uso de curcumina extraida de su fuente natural como precursor de farmacos. Metodos: los rizomas de Curcuma longa L. fueron previamente tratados; despues de estar secos, se pulverizaron y la extraccion se realizo con metanol en un bano ultrasonico. El producto deseado (curcumina) se purifico por cromatografia de columna, para ser usado posteriormente como la materia de partida en la obtencion de un analogo semisintetico. Los compuestos aislados y sintetizados se caracterizaron por metodos espectroscopicos. Resultados: se logro aislar curcumina con alto grado de pureza a partir de la Cu...
Synthesis, 2011
... Heike Wächtler a,b , Dilver Peña Fuentes a , Dirk Michalik c , Martin Köckerling a , Alexande... more ... Heike Wächtler a,b , Dilver Peña Fuentes a , Dirk Michalik c , Martin Köckerling a , Alexander Villinger a , Udo Kragl a , Quirino Arias Cedeño d , Christian Vogel* a. ... Reagents and conditions: (i) MsCl, Et 3 N, CH 2 Cl 2 , 20 min, 5 ˚C, and PTSCl, py,12 h, 5-20 ˚C; (ii) NaN 3 , 18 ...
Journal für Praktische Chemie/Chemiker-Zeitung, 1997