Aruna Kanaparthy - Academia.edu (original) (raw)

Papers by Aruna Kanaparthy

International Journal of Case Reports and Images, 2014

Introduction: The Crouzon syndrome is a rare clinical condition that affects the craniofacial ske... more Introduction: The Crouzon syndrome is a rare clinical condition that affects the craniofacial skeleton development. It accounts for about 4.8% of all the cases of craniosynostosis, and it is the most common syndrome presenting with craniosynostoses. The Crouzon syndrome's early diagnosis is critical to avoid cranial hypertension as well as visual disturbances and blindness. Children who have Crouzon syndrome have a range of problems of variable severity, from mild facial defects causing a primarily cosmetic concern, to severe symptoms affecting breathing, feeding, vision and brain development. The dental profession should have sufficient knowledge of syndromes associated with dysmorphic facies to detect patients who are unaware of their condition. Case Report: A 23yearold female patient presented to the clinic with multiple dental problems affecting masticatory efficiency and esthetics. On observation, it was seen that she had many facial and dental deformities which were suggestive of craniofacial dysostosis. The case was diagnosed as Crouzon syndrome. Conclusion: This case report emphasizes the role of a dentist in diagnosing such conditions and coordinating a multidisciplinary team for corrective measures.

Developments in medicine have resulted in an increase in the life span of people, thereby le... more Developments in medicine have resulted in an increase in the life span of people, thereby leading to an increase in the number of geriatric patients. Adverse oral health has been identified as a risk factor for several systemic disorders/diseases. Therefore, dental care should be integrated into overall health management of all geriatric patients. Increased numbers of such patients in dentistry has resulted in the preferred use of alternatives like endodontics rather than extractions to improve the longevity of the natural dentition. Special knowledge, skills and attitude are necessary for the management of the geriatric patients. This review discusses the unique challenges faced by the endodontist in carrying out root canal treatment in such individuals

1 * Reader , Endodont ics and Conservat ive Dent is t ry, Peop le Denta l , Academ y, Bhopal , Ma... more 1 * Reader , Endodont ics and Conservat ive Dent is t ry, Peop le Denta l , Academ y, Bhopal , Madhya Pradesh, Peoples Campus, Bhanpur , Bhopal , Ind ia . Emai l : draruna15@gmai l .com , draruna2008@red i f fmai l .com ; Tel . : 9630226239. 2 Professor and Head of Depar tment of Per iodont ics , Peoples Denta l Academ y, Bhopa l , Madhya Pradesh, Peoples Campus, Bhanpur , Bhopal , Ind ia . Emai l : dr rosaiah@gmai l .com , medha98@gmai l .com ; Tel . : 9893050554.

Journal of Periodontology & Implant Dentistry, 2012

Background and aims. The present study was envisaged to compare the efficacy of adjunctive use of... more Background and aims. The present study was envisaged to compare the efficacy of adjunctive use of Azithromycin with scaling and root planing (SRP) the adjunctive use Amoxicillin and SRP, and SRP alone in the treatment of chronic periodontitis. To correlate the use of N-Benzoyl DL-Arginine 2- Naphthylamide (BANA) hydrolysis test and percentage of spirochete count with the periodontal parameters before and after periodontal therapy. Materials and methods. Thirty subjects with chronic periodontitis were randomly selected and divided into three groups as follows. Group I: Subjects treated with scaling and root planing (SRP) alone. Group II: Subjects treated with SRP and systemic administration of Amoxicillin (SRP + AMOX). Group III: Subjects treated with SRP and systemic administration of Azithromycin (SRP + AZM). Periodontal parameters comprising of plaque index, bleeding index, probing pocket depth, clinical attachment level and microbiological parameters comprising of spirochete coun...

Journal of pharmaceutical and biomedical sciences, 2015

Stem cell refers to a clonogenic, undifferentiated cell that is capable of self-renewal and multi... more Stem cell refers to a clonogenic, undifferentiated cell that is capable of self-renewal and multi-lineage differentiation. They are unique and form the basis of development, growth and survival of a living organism. Stem cells are the foundation cells of every organ and tissue in the body including the periodontium. Numerous clinical techniques, including bone grafts, root surface conditioning, barrier membranes and various growth factors, have been utilised over the years in an attempt to achieve periodontal regeneration. The recent identification and isolation of stem cells from the periodontal ligament represents a significant development in the progress towards predictable periodontal regeneration. This review is an overview on the role of stem cells and tissue engineering in periodontal regeneration.

Aim-To review the use of various anti-microbial adjuvants in the treatment of periodontal disease... more Aim-To review the use of various anti-microbial adjuvants in the treatment of periodontal disease along with mandatory scaling and root planing. Background-Periodontal disease is a chronic bacterial infection of the periodontal tissues which can negatively affect the quality of life of the individual.5 to 30% of the adult human population is affected by this disease.Proper diagnosis and appropriate treatment with scaling and root planing along with the judicious use of various anti-microbial agents helps in controlling the periodontal disease.This article is aimed at reviewing the various anti-microbial agents used to combat periodontal disease.

The Journal of Contemporary Dental Practice, 2019

Aim: To evaluate the fracture resistance under static loading of endodontically treated teeth (ma... more Aim: To evaluate the fracture resistance under static loading of endodontically treated teeth (maxillary central incisors) restored with carbon fiber posts, glass fiber posts, and everStick posts. The objectives of this study were to check the fracture resistance of the everStick post and compare it with glass fiber posts and carbon fiber posts and evaluated their modes of failure. Materials and methods: An estimated 80 freshly extracted human maxillary central incisors were collected for this study. The coronal portions of 60 teeth were sectioned 4 mm incisal to the cemento-enamel junction (CEJ) and 20 teeth were left intact to be used as controls. All the samples were embedded vertically in acrylic resin blocks and the groups were divided as follows. I-control group, II-carbon fiber group, IIIglass fiber group, and IV-everStick (E-glass) group. Root canal treatment was completed in all the 80 teeth of 4 groups. Control group teeth were restored with a composite. In all other teeth, post and core placement was carried out. All specimens were mounted on a test block and subjected to static loading until fracture and the mode of fracture was recorded. Statistical analysis was carried out using ANOVA to calculate the mean values of all groups. An intergroup comparison was carried out using Tukey's post hoc test. Results: The study showed that group I showed the highest fracture resistance followed by group IV, which is everStick post group under static loading. There was a significant difference among test groups. The main mode of fracture was repairable as there was debonding of the core in all the fiber posts. Conclusion: Teeth of the control group showed highest fracture resistance and teeth restored with everStick posts showed higher fracture resistance than those restored with glass fiber or carbon fiber posts under static loading (p < 0.05). The principal mode of fracture was debonding of core and remaining root. Teeth restored without application of a post showed the highest fracture resistance than all other groups. Clinical significance: EverStick/E-glass fiber posts showed significantly higher fracture resistance than the other fiber posts and can be suggested for clinical use.

Journal of Advanced Oral Research, 2012

Introduction: The studies have demonstrated that the hydrolysis of the trypsin substrate N benzyl... more Introduction: The studies have demonstrated that the hydrolysis of the trypsin substrate N benzyl-Dl-arginase-2-naphthalamide (BANA) by sub-gingival plaque correlates best with the numbers and proportions of periodontopathogens in plaque samples and may serve as a marker of periodontal disease. Aims & Objectives:  To determine the efficacy of N benzyl-Dlarginase-2-naphthalamide (BANA) hydrolysis by sub-gingival plaque microorganisms as a diagnostic tool in periodontal disease.  To correlate the test reaction with the clinical diagnosis in healthy patients and patients suffering from chronic periodontitis. Methodology: Fifty five subjects from a periodontally defined population were evaluated for the ability of their sub-gingival plaque samples to hydrolyze a 0.67 mmol solution of BANA and correlate it with its clinical diagnosis. They were divided into 2 groups. Twenty five periodontally healthy patients were placed under group I (control) and Thirty periodontally diseased patients were placed under group II(diseased). After the clinical assessments were made and the findings recorded, 4 to 6 sub-gingival plaque samples were obtained from the buccal interdental areas around the first molar tooth in each quadrant. After dispersion in 0.6 ml of Sorensen phosphate buffer, 50 microlitres were incubated with 0.1 ml of BANA solution at 37 0 C for 18 hours. The outcome of the hydrolysis was recorded, results obtained were tabulated and subjected to statistical analysis. Result: The outcome of BANA test was highly significant (p<0.01) in periodontally diseased subjects. It can be used as a reliable indicator of BANA positive species in sub-gingival plaque. Conclusion: It can be used as a reliable indicator of BANA positive species in sub-gingival plaque.

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2016

Maximum removal of gutta percha and sealer followed by reinstrumentation is very crucial for succ... more Maximum removal of gutta percha and sealer followed by reinstrumentation is very crucial for successful re-treatment. As the bacteria or fungi surviving and thriving under the gutta percha and sealer have to be removed [1-3]. Gutta percha can be removed using K or H files along with chemical solvents. Alternatively, it can also be removed from the coronal portion using gates glidden drills or heated pluggers followed by the use of ultrasonics, lasers or Ni Ti rotary files for the remaining part of the canal [4,5]. Pro-Taper instruments (Dentsply-Maillefer Ballaigues, Switzerland) have a convex triangular cross-sectional design with different shafts. A new NiTi rotary system, ProTaper Universal Tulsa (Dentsply Tulsa, Tulsa,) is introduced. This new system is integrated with 3 ProTaper retreatment files, D1, D2, D3. The 3 ProTaper Universal System retreatment files (PTUS) are designed to facilitate the removal of filling material. Each file has different lengths, tapers, and apical tip diameters. Mtwo Retreatment Files consist of two instruments of 21mm length with active cutting tip: R1 (size 15, 0.05 taper) and R2 (size 25, 0.05 taper). They have S-shaped cross-section but a shorter pitch length to enhance the advancement of the file into the filling material. They are used at a speed of 250-350rpm and a torque of 120gcm. These instruments are characterized by two cutting edges, which cut dentine effectively [6]. Thus, the purpose of this in vitro study was to evaluate and compare the efficacy of two rotary retreatment file systems: ProTaper universal retreatment files, mtwo retreatment files and hand files (Hedstrom Files) in the removal of root canal filling material during root canal retreatment and the influence of the type of sealers zinc oxide eugenol and AH plus on the presence of debris of filling material in re-instrumented canals in single rooted mandibular premolars.

Journal of Evolution of Medical and Dental Sciences, 2016

BACKGROUND Due to increased aesthetic demands, the dentist should rely on the aesthetic principle... more BACKGROUND Due to increased aesthetic demands, the dentist should rely on the aesthetic principles that exist in nature so as to reproduce or integrate them in humans to mimic the essential beauty. The Golden proportion, Golden percentage and recurrent aesthetic dental proportion are some of the commonly used guidelines by the dental profession for better aesthetic proportion in dentition. AIM The aim of the present study was to investigate the existence of Golden Percentage and Recurrent Aesthetic Dental proportion between the widths of maxillary anterior teeth in individuals with natural aesthetic dentition. METHODS AND MATERIAL This study was conducted on 60 dental students with an aesthetic smile (30 males and 30 females) with ages ranging from 18 to 30 yrs. by obtaining prior consent. An impression of upper arch was made with alginate impression material and standardized facial photographs were obtained from each individual. Analysis was performed by operator on cast using Dial caliper and on photographs using Corel Draw software. The existence of Golden Percentage and Recurrent Aesthetic Dental proportion was investigated. The data was statistically analysed by student's paired 't' test. RESULTS This study has shown that golden percentage is observed only in the lateral incisors and is not applicable to central incisor which showed Golden percentage of 21.7% and canine which showed 13%. There was no evidence to support the existence of RED proportion. CONCLUSION Further studies need to be carried out on a larger population with different stereotypes to prove the existence of Golden percentage and RED proportion in the Indian population.

International journal of applied & basic medical research

Evaluation and comparison of serum C-reactive protein (CRP) levels in subjects with chronic and a... more Evaluation and comparison of serum C-reactive protein (CRP) levels in subjects with chronic and aggressive periodontitis. Based on the periodontal status, 45 subjects were selected and divided into three groups. Group I - subjects with clinically healthy periodontium, Group II - generalized aggressive periodontitis (GAP), and Group III - chronic periodontitis (CP). Blood samples were collected from subjects for measurement of CRP. Periodontal parameters include plaque index (PI), gingival index, bleeding index (BI), probing pocket depth (PPD), and clinical attachment loss (CAL) were assessed. CRP levels were assessed by means of a commercially available high sensitivity-CRP enzyme immunoassay kit. CRP levels were increased in Group III (6.0671 ± 3.15639 mg/L) and Group II subjects (4.5453 ± 2.88116 mg/L) compared to the Group I (1.0180 ± 0.94069 mg/L). CRP levels showed a positive correlation with all clinical parameters in Group I subjects. BI (r = 0.073), PI (r = 0.120) showed a p...

International Journal of Case Reports and Images, 2014

Introduction: The Crouzon syndrome is a rare clinical condition that affects the craniofacial ske... more Introduction: The Crouzon syndrome is a rare clinical condition that affects the craniofacial skeleton development. It accounts for about 4.8% of all the cases of craniosynostosis, and it is the most common syndrome presenting with craniosynostoses. The Crouzon syndrome's early diagnosis is critical to avoid cranial hypertension as well as visual disturbances and blindness. Children who have Crouzon syndrome have a range of problems of variable severity, from mild facial defects causing a primarily cosmetic concern, to severe symptoms affecting breathing, feeding, vision and brain development. The dental profession should have sufficient knowledge of syndromes associated with dysmorphic facies to detect patients who are unaware of their condition. Case Report: A 23yearold female patient presented to the clinic with multiple dental problems affecting masticatory efficiency and esthetics. On observation, it was seen that she had many facial and dental deformities which were suggestive of craniofacial dysostosis. The case was diagnosed as Crouzon syndrome. Conclusion: This case report emphasizes the role of a dentist in diagnosing such conditions and coordinating a multidisciplinary team for corrective measures.

International Journal of Medical Research & Health Sciences, 2016

Aim: The objective of the present research was to evaluate and to compare the cytotoxicity of fou... more Aim: The objective of the present research was to evaluate and to compare the cytotoxicity of four commonly used endodontic sealers Apexit Plus, AH plus, Sankin, and Endofloss. The cytotoxicity was evaluated after setting of the sealers at different time intervals. Materials and Methods: Mouse skin fibroblasts L-929 was obtained from cell repository centre of national centre for cell science Pune, India. The cells were grown as monolayer cultures in Dulbeccos Modified eagle Medium (DMEM). Each of the test materials were mixed according to the manufactures instruction and was allowed to set. 0.1ml of each of the set sealers was placed in the petriplates in direct contact with the fibroblasts at 24 and 48 hrs intervals and evaluated for cytotoxicity. The percentage viability of the fibroblasts were calculated and evaluated statistically. Results: The statistical analysis revealed that Apexit Plus showed slight to moderate toxicity at 24 and 48 hrs, when compared with other sealers. Sankin showed maximum toxicity at all time intervals. Conclusion: All tested endodontic sealers demonstrated varying amount of cytotoxicity at different time intervals. Apexit Plus showed the least amount of cytotoxicity and Sankin showed the highest level of cytotoxicity.

Peripheral ameloblastoma is a rare, but develops in the soft tissues of the gingiva and mucosa an... more Peripheral ameloblastoma is a rare, but develops in the soft tissues of the gingiva and mucosa and exhibits an innocuous clinical behavior. This paper reports a case of peripheral ameloblastoma in a 35-year-old female that presented as a painless swelling on the mandibular anterior labial attached gingiva. This reports emphasis the need for submitting all excised tissue for microscopic examination and to include ameloblastoma in the differential diagnosis a gingival lesion which clinically resembles a pyogenic granuloma, peripheral giant cell granuloma, or parulis/gumboil.

General dentistry

Periodontal subgingival pathogens affect local and systemic immune and inflammatory response and ... more Periodontal subgingival pathogens affect local and systemic immune and inflammatory response and cause the release of cytokines; this results in periodontal destruction and initiation of an acute phase systemic inflammatory response characterized by the release of C-reactive proteins (CRP). This study set out to evaluate the serum concentration of CRP that can be used as a marker of periodontal disease as well as a risk indicator for cardiovascular disease. Based on their periodontal status, 45 patients were divided into three groups. The following clinical parameters were recorded: plaque index, gingival index, bleeding index, probing pocket depth, and clinical attachment levels. Scoring was done on six tooth surfaces for all teeth. For the CRP assessment, blood samples were collected from subjects at the time of clinical examination. The results indicated an increase in serum CRP levels in patients with generalized aggressive periodontitis and chronic periodontitis as compared to ...

IOSR Journal of Pharmacy (IOSRPHR), 2013

IOSR Journal of Dental and Medical Sciences, 2013

Pulpal infection may cause a tissue destructive process that proceeds from the apical region of a... more Pulpal infection may cause a tissue destructive process that proceeds from the apical region of a tooth toward the gingival margin. The term "retrograde periodontitis" was suggested in order to differentiate this from marginal periodontitis in which the infection spreads from the gingival margin toward the root apex. The relationship between periodontal and pulpal disease was first described by Simring and Goldberg in 1964 1. Pulpodontic-periodontic syndrome has been used to define a syndrome involving inflammation or degeneration of the pulp with a periodontal pocket adjacent to the same tooth. This syndrome can be initiated by either pulpal or periodontal disease and may manifest pulpal and periodontal symptoms. In general, pulpal infection has the potential to initiate inflammatory changes in the alveolus at both apical and non-apical locations of teeth. Combined lesions are those that occur where an endodontically induced periapical lesion exists on a tooth that is also periodontally involved. All of these conditions can be placed under the general term periodontitis associated with pulpal disease.

Dentistry, 2012

Introduction: The Crouzon syndrome is a rare clinical condition that affects the craniofacial ske... more Introduction: The Crouzon syndrome is a rare clinical condition that affects the craniofacial skeleton development. It accounts for about 4.8% of all the cases of craniosynostosis, and it is the most common syndrome presenting with craniosynostoses. The Crouzon syndrome's early diagnosis is critical to avoid cranial hypertension as well as visual disturbances and blindness. Children who have Crouzon syndrome have a range of problems of variable severity, from mild facial defects causing a primarily cosmetic concern, to severe symptoms affecting breathing, feeding, vision and brain development. The dental profession should have sufficient knowledge of syndromes associated with dysmorphic facies to detect patients who are unaware of their condition. Case Report: A 23yearold female patient presented to the clinic with multiple dental problems affecting masticatory efficiency and esthetics. On observation, it was seen that she had many facial and dental deformities which were suggestive of craniofacial dysostosis. The case was diagnosed as Crouzon syndrome. Conclusion: This case report emphasizes the role of a dentist in diagnosing such conditions and coordinating a multidisciplinary team for corrective measures.

International Journal of Case Reports and Images, 2014

Introduction: The Crouzon syndrome is a rare clinical condition that affects the craniofacial ske... more Introduction: The Crouzon syndrome is a rare clinical condition that affects the craniofacial skeleton development. It accounts for about 4.8% of all the cases of craniosynostosis, and it is the most common syndrome presenting with craniosynostoses. The Crouzon syndrome's early diagnosis is critical to avoid cranial hypertension as well as visual disturbances and blindness. Children who have Crouzon syndrome have a range of problems of variable severity, from mild facial defects causing a primarily cosmetic concern, to severe symptoms affecting breathing, feeding, vision and brain development. The dental profession should have sufficient knowledge of syndromes associated with dysmorphic facies to detect patients who are unaware of their condition. Case Report: A 23yearold female patient presented to the clinic with multiple dental problems affecting masticatory efficiency and esthetics. On observation, it was seen that she had many facial and dental deformities which were suggestive of craniofacial dysostosis. The case was diagnosed as Crouzon syndrome. Conclusion: This case report emphasizes the role of a dentist in diagnosing such conditions and coordinating a multidisciplinary team for corrective measures.

Developments in medicine have resulted in an increase in the life span of people, thereby le... more Developments in medicine have resulted in an increase in the life span of people, thereby leading to an increase in the number of geriatric patients. Adverse oral health has been identified as a risk factor for several systemic disorders/diseases. Therefore, dental care should be integrated into overall health management of all geriatric patients. Increased numbers of such patients in dentistry has resulted in the preferred use of alternatives like endodontics rather than extractions to improve the longevity of the natural dentition. Special knowledge, skills and attitude are necessary for the management of the geriatric patients. This review discusses the unique challenges faced by the endodontist in carrying out root canal treatment in such individuals

1 * Reader , Endodont ics and Conservat ive Dent is t ry, Peop le Denta l , Academ y, Bhopal , Ma... more 1 * Reader , Endodont ics and Conservat ive Dent is t ry, Peop le Denta l , Academ y, Bhopal , Madhya Pradesh, Peoples Campus, Bhanpur , Bhopal , Ind ia . Emai l : draruna15@gmai l .com , draruna2008@red i f fmai l .com ; Tel . : 9630226239. 2 Professor and Head of Depar tment of Per iodont ics , Peoples Denta l Academ y, Bhopa l , Madhya Pradesh, Peoples Campus, Bhanpur , Bhopal , Ind ia . Emai l : dr rosaiah@gmai l .com , medha98@gmai l .com ; Tel . : 9893050554.

Journal of Periodontology & Implant Dentistry, 2012

Background and aims. The present study was envisaged to compare the efficacy of adjunctive use of... more Background and aims. The present study was envisaged to compare the efficacy of adjunctive use of Azithromycin with scaling and root planing (SRP) the adjunctive use Amoxicillin and SRP, and SRP alone in the treatment of chronic periodontitis. To correlate the use of N-Benzoyl DL-Arginine 2- Naphthylamide (BANA) hydrolysis test and percentage of spirochete count with the periodontal parameters before and after periodontal therapy. Materials and methods. Thirty subjects with chronic periodontitis were randomly selected and divided into three groups as follows. Group I: Subjects treated with scaling and root planing (SRP) alone. Group II: Subjects treated with SRP and systemic administration of Amoxicillin (SRP + AMOX). Group III: Subjects treated with SRP and systemic administration of Azithromycin (SRP + AZM). Periodontal parameters comprising of plaque index, bleeding index, probing pocket depth, clinical attachment level and microbiological parameters comprising of spirochete coun...

Journal of pharmaceutical and biomedical sciences, 2015

Stem cell refers to a clonogenic, undifferentiated cell that is capable of self-renewal and multi... more Stem cell refers to a clonogenic, undifferentiated cell that is capable of self-renewal and multi-lineage differentiation. They are unique and form the basis of development, growth and survival of a living organism. Stem cells are the foundation cells of every organ and tissue in the body including the periodontium. Numerous clinical techniques, including bone grafts, root surface conditioning, barrier membranes and various growth factors, have been utilised over the years in an attempt to achieve periodontal regeneration. The recent identification and isolation of stem cells from the periodontal ligament represents a significant development in the progress towards predictable periodontal regeneration. This review is an overview on the role of stem cells and tissue engineering in periodontal regeneration.

Aim-To review the use of various anti-microbial adjuvants in the treatment of periodontal disease... more Aim-To review the use of various anti-microbial adjuvants in the treatment of periodontal disease along with mandatory scaling and root planing. Background-Periodontal disease is a chronic bacterial infection of the periodontal tissues which can negatively affect the quality of life of the individual.5 to 30% of the adult human population is affected by this disease.Proper diagnosis and appropriate treatment with scaling and root planing along with the judicious use of various anti-microbial agents helps in controlling the periodontal disease.This article is aimed at reviewing the various anti-microbial agents used to combat periodontal disease.

The Journal of Contemporary Dental Practice, 2019

Aim: To evaluate the fracture resistance under static loading of endodontically treated teeth (ma... more Aim: To evaluate the fracture resistance under static loading of endodontically treated teeth (maxillary central incisors) restored with carbon fiber posts, glass fiber posts, and everStick posts. The objectives of this study were to check the fracture resistance of the everStick post and compare it with glass fiber posts and carbon fiber posts and evaluated their modes of failure. Materials and methods: An estimated 80 freshly extracted human maxillary central incisors were collected for this study. The coronal portions of 60 teeth were sectioned 4 mm incisal to the cemento-enamel junction (CEJ) and 20 teeth were left intact to be used as controls. All the samples were embedded vertically in acrylic resin blocks and the groups were divided as follows. I-control group, II-carbon fiber group, IIIglass fiber group, and IV-everStick (E-glass) group. Root canal treatment was completed in all the 80 teeth of 4 groups. Control group teeth were restored with a composite. In all other teeth, post and core placement was carried out. All specimens were mounted on a test block and subjected to static loading until fracture and the mode of fracture was recorded. Statistical analysis was carried out using ANOVA to calculate the mean values of all groups. An intergroup comparison was carried out using Tukey's post hoc test. Results: The study showed that group I showed the highest fracture resistance followed by group IV, which is everStick post group under static loading. There was a significant difference among test groups. The main mode of fracture was repairable as there was debonding of the core in all the fiber posts. Conclusion: Teeth of the control group showed highest fracture resistance and teeth restored with everStick posts showed higher fracture resistance than those restored with glass fiber or carbon fiber posts under static loading (p < 0.05). The principal mode of fracture was debonding of core and remaining root. Teeth restored without application of a post showed the highest fracture resistance than all other groups. Clinical significance: EverStick/E-glass fiber posts showed significantly higher fracture resistance than the other fiber posts and can be suggested for clinical use.

Journal of Advanced Oral Research, 2012

Introduction: The studies have demonstrated that the hydrolysis of the trypsin substrate N benzyl... more Introduction: The studies have demonstrated that the hydrolysis of the trypsin substrate N benzyl-Dl-arginase-2-naphthalamide (BANA) by sub-gingival plaque correlates best with the numbers and proportions of periodontopathogens in plaque samples and may serve as a marker of periodontal disease. Aims & Objectives:  To determine the efficacy of N benzyl-Dlarginase-2-naphthalamide (BANA) hydrolysis by sub-gingival plaque microorganisms as a diagnostic tool in periodontal disease.  To correlate the test reaction with the clinical diagnosis in healthy patients and patients suffering from chronic periodontitis. Methodology: Fifty five subjects from a periodontally defined population were evaluated for the ability of their sub-gingival plaque samples to hydrolyze a 0.67 mmol solution of BANA and correlate it with its clinical diagnosis. They were divided into 2 groups. Twenty five periodontally healthy patients were placed under group I (control) and Thirty periodontally diseased patients were placed under group II(diseased). After the clinical assessments were made and the findings recorded, 4 to 6 sub-gingival plaque samples were obtained from the buccal interdental areas around the first molar tooth in each quadrant. After dispersion in 0.6 ml of Sorensen phosphate buffer, 50 microlitres were incubated with 0.1 ml of BANA solution at 37 0 C for 18 hours. The outcome of the hydrolysis was recorded, results obtained were tabulated and subjected to statistical analysis. Result: The outcome of BANA test was highly significant (p<0.01) in periodontally diseased subjects. It can be used as a reliable indicator of BANA positive species in sub-gingival plaque. Conclusion: It can be used as a reliable indicator of BANA positive species in sub-gingival plaque.

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2016

Maximum removal of gutta percha and sealer followed by reinstrumentation is very crucial for succ... more Maximum removal of gutta percha and sealer followed by reinstrumentation is very crucial for successful re-treatment. As the bacteria or fungi surviving and thriving under the gutta percha and sealer have to be removed [1-3]. Gutta percha can be removed using K or H files along with chemical solvents. Alternatively, it can also be removed from the coronal portion using gates glidden drills or heated pluggers followed by the use of ultrasonics, lasers or Ni Ti rotary files for the remaining part of the canal [4,5]. Pro-Taper instruments (Dentsply-Maillefer Ballaigues, Switzerland) have a convex triangular cross-sectional design with different shafts. A new NiTi rotary system, ProTaper Universal Tulsa (Dentsply Tulsa, Tulsa,) is introduced. This new system is integrated with 3 ProTaper retreatment files, D1, D2, D3. The 3 ProTaper Universal System retreatment files (PTUS) are designed to facilitate the removal of filling material. Each file has different lengths, tapers, and apical tip diameters. Mtwo Retreatment Files consist of two instruments of 21mm length with active cutting tip: R1 (size 15, 0.05 taper) and R2 (size 25, 0.05 taper). They have S-shaped cross-section but a shorter pitch length to enhance the advancement of the file into the filling material. They are used at a speed of 250-350rpm and a torque of 120gcm. These instruments are characterized by two cutting edges, which cut dentine effectively [6]. Thus, the purpose of this in vitro study was to evaluate and compare the efficacy of two rotary retreatment file systems: ProTaper universal retreatment files, mtwo retreatment files and hand files (Hedstrom Files) in the removal of root canal filling material during root canal retreatment and the influence of the type of sealers zinc oxide eugenol and AH plus on the presence of debris of filling material in re-instrumented canals in single rooted mandibular premolars.

Journal of Evolution of Medical and Dental Sciences, 2016

BACKGROUND Due to increased aesthetic demands, the dentist should rely on the aesthetic principle... more BACKGROUND Due to increased aesthetic demands, the dentist should rely on the aesthetic principles that exist in nature so as to reproduce or integrate them in humans to mimic the essential beauty. The Golden proportion, Golden percentage and recurrent aesthetic dental proportion are some of the commonly used guidelines by the dental profession for better aesthetic proportion in dentition. AIM The aim of the present study was to investigate the existence of Golden Percentage and Recurrent Aesthetic Dental proportion between the widths of maxillary anterior teeth in individuals with natural aesthetic dentition. METHODS AND MATERIAL This study was conducted on 60 dental students with an aesthetic smile (30 males and 30 females) with ages ranging from 18 to 30 yrs. by obtaining prior consent. An impression of upper arch was made with alginate impression material and standardized facial photographs were obtained from each individual. Analysis was performed by operator on cast using Dial caliper and on photographs using Corel Draw software. The existence of Golden Percentage and Recurrent Aesthetic Dental proportion was investigated. The data was statistically analysed by student's paired 't' test. RESULTS This study has shown that golden percentage is observed only in the lateral incisors and is not applicable to central incisor which showed Golden percentage of 21.7% and canine which showed 13%. There was no evidence to support the existence of RED proportion. CONCLUSION Further studies need to be carried out on a larger population with different stereotypes to prove the existence of Golden percentage and RED proportion in the Indian population.

International journal of applied & basic medical research

Evaluation and comparison of serum C-reactive protein (CRP) levels in subjects with chronic and a... more Evaluation and comparison of serum C-reactive protein (CRP) levels in subjects with chronic and aggressive periodontitis. Based on the periodontal status, 45 subjects were selected and divided into three groups. Group I - subjects with clinically healthy periodontium, Group II - generalized aggressive periodontitis (GAP), and Group III - chronic periodontitis (CP). Blood samples were collected from subjects for measurement of CRP. Periodontal parameters include plaque index (PI), gingival index, bleeding index (BI), probing pocket depth (PPD), and clinical attachment loss (CAL) were assessed. CRP levels were assessed by means of a commercially available high sensitivity-CRP enzyme immunoassay kit. CRP levels were increased in Group III (6.0671 ± 3.15639 mg/L) and Group II subjects (4.5453 ± 2.88116 mg/L) compared to the Group I (1.0180 ± 0.94069 mg/L). CRP levels showed a positive correlation with all clinical parameters in Group I subjects. BI (r = 0.073), PI (r = 0.120) showed a p...

International Journal of Case Reports and Images, 2014

Introduction: The Crouzon syndrome is a rare clinical condition that affects the craniofacial ske... more Introduction: The Crouzon syndrome is a rare clinical condition that affects the craniofacial skeleton development. It accounts for about 4.8% of all the cases of craniosynostosis, and it is the most common syndrome presenting with craniosynostoses. The Crouzon syndrome's early diagnosis is critical to avoid cranial hypertension as well as visual disturbances and blindness. Children who have Crouzon syndrome have a range of problems of variable severity, from mild facial defects causing a primarily cosmetic concern, to severe symptoms affecting breathing, feeding, vision and brain development. The dental profession should have sufficient knowledge of syndromes associated with dysmorphic facies to detect patients who are unaware of their condition. Case Report: A 23yearold female patient presented to the clinic with multiple dental problems affecting masticatory efficiency and esthetics. On observation, it was seen that she had many facial and dental deformities which were suggestive of craniofacial dysostosis. The case was diagnosed as Crouzon syndrome. Conclusion: This case report emphasizes the role of a dentist in diagnosing such conditions and coordinating a multidisciplinary team for corrective measures.

International Journal of Medical Research & Health Sciences, 2016

Aim: The objective of the present research was to evaluate and to compare the cytotoxicity of fou... more Aim: The objective of the present research was to evaluate and to compare the cytotoxicity of four commonly used endodontic sealers Apexit Plus, AH plus, Sankin, and Endofloss. The cytotoxicity was evaluated after setting of the sealers at different time intervals. Materials and Methods: Mouse skin fibroblasts L-929 was obtained from cell repository centre of national centre for cell science Pune, India. The cells were grown as monolayer cultures in Dulbeccos Modified eagle Medium (DMEM). Each of the test materials were mixed according to the manufactures instruction and was allowed to set. 0.1ml of each of the set sealers was placed in the petriplates in direct contact with the fibroblasts at 24 and 48 hrs intervals and evaluated for cytotoxicity. The percentage viability of the fibroblasts were calculated and evaluated statistically. Results: The statistical analysis revealed that Apexit Plus showed slight to moderate toxicity at 24 and 48 hrs, when compared with other sealers. Sankin showed maximum toxicity at all time intervals. Conclusion: All tested endodontic sealers demonstrated varying amount of cytotoxicity at different time intervals. Apexit Plus showed the least amount of cytotoxicity and Sankin showed the highest level of cytotoxicity.

Peripheral ameloblastoma is a rare, but develops in the soft tissues of the gingiva and mucosa an... more Peripheral ameloblastoma is a rare, but develops in the soft tissues of the gingiva and mucosa and exhibits an innocuous clinical behavior. This paper reports a case of peripheral ameloblastoma in a 35-year-old female that presented as a painless swelling on the mandibular anterior labial attached gingiva. This reports emphasis the need for submitting all excised tissue for microscopic examination and to include ameloblastoma in the differential diagnosis a gingival lesion which clinically resembles a pyogenic granuloma, peripheral giant cell granuloma, or parulis/gumboil.

General dentistry

Periodontal subgingival pathogens affect local and systemic immune and inflammatory response and ... more Periodontal subgingival pathogens affect local and systemic immune and inflammatory response and cause the release of cytokines; this results in periodontal destruction and initiation of an acute phase systemic inflammatory response characterized by the release of C-reactive proteins (CRP). This study set out to evaluate the serum concentration of CRP that can be used as a marker of periodontal disease as well as a risk indicator for cardiovascular disease. Based on their periodontal status, 45 patients were divided into three groups. The following clinical parameters were recorded: plaque index, gingival index, bleeding index, probing pocket depth, and clinical attachment levels. Scoring was done on six tooth surfaces for all teeth. For the CRP assessment, blood samples were collected from subjects at the time of clinical examination. The results indicated an increase in serum CRP levels in patients with generalized aggressive periodontitis and chronic periodontitis as compared to ...

IOSR Journal of Pharmacy (IOSRPHR), 2013

IOSR Journal of Dental and Medical Sciences, 2013

Pulpal infection may cause a tissue destructive process that proceeds from the apical region of a... more Pulpal infection may cause a tissue destructive process that proceeds from the apical region of a tooth toward the gingival margin. The term "retrograde periodontitis" was suggested in order to differentiate this from marginal periodontitis in which the infection spreads from the gingival margin toward the root apex. The relationship between periodontal and pulpal disease was first described by Simring and Goldberg in 1964 1. Pulpodontic-periodontic syndrome has been used to define a syndrome involving inflammation or degeneration of the pulp with a periodontal pocket adjacent to the same tooth. This syndrome can be initiated by either pulpal or periodontal disease and may manifest pulpal and periodontal symptoms. In general, pulpal infection has the potential to initiate inflammatory changes in the alveolus at both apical and non-apical locations of teeth. Combined lesions are those that occur where an endodontically induced periapical lesion exists on a tooth that is also periodontally involved. All of these conditions can be placed under the general term periodontitis associated with pulpal disease.

Dentistry, 2012

Introduction: The Crouzon syndrome is a rare clinical condition that affects the craniofacial ske... more Introduction: The Crouzon syndrome is a rare clinical condition that affects the craniofacial skeleton development. It accounts for about 4.8% of all the cases of craniosynostosis, and it is the most common syndrome presenting with craniosynostoses. The Crouzon syndrome's early diagnosis is critical to avoid cranial hypertension as well as visual disturbances and blindness. Children who have Crouzon syndrome have a range of problems of variable severity, from mild facial defects causing a primarily cosmetic concern, to severe symptoms affecting breathing, feeding, vision and brain development. The dental profession should have sufficient knowledge of syndromes associated with dysmorphic facies to detect patients who are unaware of their condition. Case Report: A 23yearold female patient presented to the clinic with multiple dental problems affecting masticatory efficiency and esthetics. On observation, it was seen that she had many facial and dental deformities which were suggestive of craniofacial dysostosis. The case was diagnosed as Crouzon syndrome. Conclusion: This case report emphasizes the role of a dentist in diagnosing such conditions and coordinating a multidisciplinary team for corrective measures.