Ashish Pathak - Academia.edu (original) (raw)

Ashish Pathak

Uploads

Papers by Ashish Pathak

Research paper thumbnail of A facile method for deprotection of trityl ethers using column chromatography

Tetrahedron Letters, 2001

A mild, efficient and inexpensive detritylation method is reported that uses trifluoroacetic acid... more A mild, efficient and inexpensive detritylation method is reported that uses trifluoroacetic acid on a silica gel column to obtain pure, detritylated compounds in one-step. This method is applicable to acid stable as well as acid sensitive compounds with only slight alterations in the procedure. Nineteen examples are given.

Research paper thumbnail of Persistent hyperinsulinemic hypoglycemia of infancysuccessful therapy with nifedipine

Indian Journal of Pediatrics, 2002

Recent studies have demonstrated a role for calcium channel blocking agents in the treatment of p... more Recent studies have demonstrated a role for calcium channel blocking agents in the treatment of persistent hyperinsulinemic hypoglycemia of infancy. We report a 30 day old infant with PHHI whom we successfully treated with oral nifedipine alone.

Research paper thumbnail of Chemistry and Biological Activities of the Genera Tinospora

Pharmaceutical Biology, 1995

A IlSTRA CT .\' (,I'cral .vpct:ies of the genera Tinospora (Menispt'rllwce (lC) (/fe widely distr... more A IlSTRA CT .\' (,I'cral .vpct:ies of the genera Tinospora (Menispt'rllwce (lC) (/fe widely distributed over Asia (lml Africa (flld arc well-known for their medicinal properties. Conseqllelllly. they have been investigated extensively over the /cHt four decades. A brief review of the chemical constill/ents in these species (Jlld the hiological activities reported is pre sented, 1'. crispo (S) T. mala/Jarica (S) Khudu et 01 .. 1964

Research paper thumbnail of NMR spectroscopy of steroidal sapogenins and steroidal saponins: An update

Magnetic Resonance in Chemistry, 1995

The 13C NMR chemical shifts of 126 Steroidal sapogenins published between 1983 and 1993 are liste... more The 13C NMR chemical shifts of 126 Steroidal sapogenins published between 1983 and 1993 are listed and critical spectral features and advances made in the NMR characterization of these compounds are discussed as a guide for the identification of the parent skeleton and the determination of substitution patterns. The NMR spectroscopic methods applicable to deduce the complete structure of the oligosaccharide moiety and its linkage to the sapogenin residue are also presented to elucidate the structure of steroidal saponins.

Research paper thumbnail of Influence of skeletal alteration of lignoids on carbon-13 NMR chemical shifts

Magnetic Resonance in Chemistry, 1994

The characteristic 13C NMR chemical shift ranges as a guide for the establishment of the parent s... more The characteristic 13C NMR chemical shift ranges as a guide for the establishment of the parent skeletons of various categories and subcategories of lignoids (lignans, neolignans and oxyneolignans) and for the determination of the substitution pattern of the side-chain are tabulated.

Research paper thumbnail of A facile method for deprotection of trityl ethers using column chromatography

Tetrahedron Letters, 2001

A mild, efficient and inexpensive detritylation method is reported that uses trifluoroacetic acid... more A mild, efficient and inexpensive detritylation method is reported that uses trifluoroacetic acid on a silica gel column to obtain pure, detritylated compounds in one-step. This method is applicable to acid stable as well as acid sensitive compounds with only slight alterations in the procedure. Nineteen examples are given.

Research paper thumbnail of Persistent hyperinsulinemic hypoglycemia of infancysuccessful therapy with nifedipine

Indian Journal of Pediatrics, 2002

Recent studies have demonstrated a role for calcium channel blocking agents in the treatment of p... more Recent studies have demonstrated a role for calcium channel blocking agents in the treatment of persistent hyperinsulinemic hypoglycemia of infancy. We report a 30 day old infant with PHHI whom we successfully treated with oral nifedipine alone.

Research paper thumbnail of Chemistry and Biological Activities of the Genera Tinospora

Pharmaceutical Biology, 1995

A IlSTRA CT .\' (,I'cral .vpct:ies of the genera Tinospora (Menispt'rllwce (lC) (/fe widely distr... more A IlSTRA CT .\' (,I'cral .vpct:ies of the genera Tinospora (Menispt'rllwce (lC) (/fe widely distributed over Asia (lml Africa (flld arc well-known for their medicinal properties. Conseqllelllly. they have been investigated extensively over the /cHt four decades. A brief review of the chemical constill/ents in these species (Jlld the hiological activities reported is pre sented, 1'. crispo (S) T. mala/Jarica (S) Khudu et 01 .. 1964

Research paper thumbnail of NMR spectroscopy of steroidal sapogenins and steroidal saponins: An update

Magnetic Resonance in Chemistry, 1995

The 13C NMR chemical shifts of 126 Steroidal sapogenins published between 1983 and 1993 are liste... more The 13C NMR chemical shifts of 126 Steroidal sapogenins published between 1983 and 1993 are listed and critical spectral features and advances made in the NMR characterization of these compounds are discussed as a guide for the identification of the parent skeleton and the determination of substitution patterns. The NMR spectroscopic methods applicable to deduce the complete structure of the oligosaccharide moiety and its linkage to the sapogenin residue are also presented to elucidate the structure of steroidal saponins.

Research paper thumbnail of Influence of skeletal alteration of lignoids on carbon-13 NMR chemical shifts

Magnetic Resonance in Chemistry, 1994

The characteristic 13C NMR chemical shift ranges as a guide for the establishment of the parent s... more The characteristic 13C NMR chemical shift ranges as a guide for the establishment of the parent skeletons of various categories and subcategories of lignoids (lignans, neolignans and oxyneolignans) and for the determination of the substitution pattern of the side-chain are tabulated.

Log In