Ashraful Islam - Academia.edu (original) (raw)
Papers by Ashraful Islam
British Medical Journal, 1989
Archives of Disease in Childhood, 1986
European Journal of Clinical Nutrition, 1997
Objectives: To evaluate the effect of vitamin A supplementation 24 h after delivery on breastmilk... more Objectives: To evaluate the effect of vitamin A supplementation 24 h after delivery on breastmilk retinol concentration. Methods: Fifty low income women were randomly assigned to a single oral dose of 209 mmol of Vitamin A or none at delivery. Maternal serum and breastmilk retinol levels and infant morbidity and anthropometry were serially assessed. Results: Mean (95% CI) serum retinol levels increased in the supplemented mothers at 2.77 (2.3, 3.2) compared to 1.15 (0.9, 1.4) mmol/l in controls (P`0.05) and remained at a signi®cantly higher level of 1.59 (1.4, 1.8) mmul/l compared to 1.33 (1.8, 1.5) mmol/l in the control group (P`0.001) up to a period of three months. Breastmilk retinol concentration was also greater at 24 h after supplementation, mean (CI) 11.34 (9.0, 13.7) mmol/l, compared to 2.95 (2.3, 3.6) mmol/l in the control group (P`0.0001), and remained higher for the next six months at 1.06 (0.9, ,1.3) mmol/l compared to 0.73 (0.6, 0.8) mmol/l in the control group (P`0.02). Infants of the supplemented mothers had reduced mean duration of respiratory tract infection of 3.1 (2.7, 3.5) days compared to 3.7 (3.3, 4.2) days (P`0.03) and mean incidence of febrile illness 0.1 (0.1, 0.1) compared to control infants 0.3 (0.3, 0.3) days, (P`0.002). Conclusion: Vitamin A supplementation of malnourished mothers maintains higher breastmilk retinol concentration for at least six months and reduces the duration of respiratory tract infection and febrile illness in their breastfed infants.
British Medical Journal, 1989
Archives of Disease in Childhood, 1986
European Journal of Clinical Nutrition, 1997
Objectives: To evaluate the effect of vitamin A supplementation 24 h after delivery on breastmilk... more Objectives: To evaluate the effect of vitamin A supplementation 24 h after delivery on breastmilk retinol concentration. Methods: Fifty low income women were randomly assigned to a single oral dose of 209 mmol of Vitamin A or none at delivery. Maternal serum and breastmilk retinol levels and infant morbidity and anthropometry were serially assessed. Results: Mean (95% CI) serum retinol levels increased in the supplemented mothers at 2.77 (2.3, 3.2) compared to 1.15 (0.9, 1.4) mmol/l in controls (P`0.05) and remained at a signi®cantly higher level of 1.59 (1.4, 1.8) mmul/l compared to 1.33 (1.8, 1.5) mmol/l in the control group (P`0.001) up to a period of three months. Breastmilk retinol concentration was also greater at 24 h after supplementation, mean (CI) 11.34 (9.0, 13.7) mmol/l, compared to 2.95 (2.3, 3.6) mmol/l in the control group (P`0.0001), and remained higher for the next six months at 1.06 (0.9, ,1.3) mmol/l compared to 0.73 (0.6, 0.8) mmol/l in the control group (P`0.02). Infants of the supplemented mothers had reduced mean duration of respiratory tract infection of 3.1 (2.7, 3.5) days compared to 3.7 (3.3, 4.2) days (P`0.03) and mean incidence of febrile illness 0.1 (0.1, 0.1) compared to control infants 0.3 (0.3, 0.3) days, (P`0.002). Conclusion: Vitamin A supplementation of malnourished mothers maintains higher breastmilk retinol concentration for at least six months and reduces the duration of respiratory tract infection and febrile illness in their breastfed infants.