Atadan Tunaci - Academia.edu (original) (raw)
Papers by Atadan Tunaci
Turkiye Klinikleri Radiology - Special Topics, 2021
Radiology, Jun 1, 1996
To evaluate the usefulness of self-expanding nitinol stents in the palliative treatment of malign... more To evaluate the usefulness of self-expanding nitinol stents in the palliative treatment of malignant dysphagia. Eighty self-expanding nitinol stents were placed in 59 patients (43 men, 16 women; mean age, 55 years; age range, 23-75 years) with inoperable malignant stenosis due to squamous cell carcinoma of the esophagus (n = 36), adenocarcinoma (n = 19), invasion of the esophagus due to carcinoma of the lung (n = 2), and recurrent anastomotic carcinoma (n = 2). Dysphagia was graded on a scale of 0 to 3. Follow-up esophagograms were obtained to evaluate stent patency. Stent placement was successful in all patients. The severity of dysphagia decreased at least one grade in all but one patient. Tumor ingrowth and overgrowth were seen in 21 (36%) patients 2 days to 7 months after stent placement and caused recurrent dysphagia. These 21 patients underwent balloon dilation and additional stent placement. A mediastinal fistula was seen in three patients (5%), ulceration in four (7%), stent torsion in three (5%), and incomplete expansion of the stent in two (2%). Repeat intervention was necessary in 51% of the patients. There is a substantial range of drawbacks and complications associated with the use of self-expanding nitinol stents for palliation of malignant esophageal strictures. A covering would be necessary to prevent tumor ingrowth.
medRxiv (Cold Spring Harbor Laboratory), May 14, 2022
doi: medRxiv preprint NOTE: This preprint reports new research that has not been certified by pee... more doi: medRxiv preprint NOTE: This preprint reports new research that has not been certified by peer review and should not be used to guide clinical practice.
Canadian Journal of Infectious Diseases & Medical Microbiology, Sep 29, 2022
Background. orax computed tomography (CT) imaging is widely used as a diagnostic method in the di... more Background. orax computed tomography (CT) imaging is widely used as a diagnostic method in the diagnosis of coronavirus disease 2019 (COVID-19)-related pneumonia. Radiological di erential diagnosis and isolation of other viral agents causing pneumonia in patients have gained importance, particularly during the pandemic. Aims. We aimed to investigate whether there is a di erence between CT images from patients with COVID-19-associated pneumonia compared to CT images of patients with pneumonia due to other viral agents and which nding may be more e ective in diagnosis. Study Design. e study included 249 adult patients with pneumonia identi ed by thorax CT examination and with a positive COVID-19 RT-PCR test compared to 94 patients diagnosed with non-COVID-19 pneumonia (viral PCR positive but no bacterial or fungal agents detected in other cultures) between 2015 and 2019. CT images were retrospectively analyzed using the PACS system. CT ndings were evaluated by two radiologists with 5 and 20 years of experience, in a blinded fashion, and the outcome was decided by consensus. Methods. Demographic data (age, gender, and known chronic disease) and CT imaging ndings (percentage of involvement, number of lesions, distribution preference, dominant pattern, ground-glass opacity distribution pattern, nodule, tree in bud sign, interstitial changes, crazy paving sign, reversed halo sign, vacuolar sign, halo sign, vascular enlargement, linear opacities, traction bronchiectasis, peribronchial wall thickness, air trapping, pleural retraction, pleural e usion, pericardial e usion, cavitation, mediastinal/hilar lymphadenopathy, dominant lesion size, consolidation, subpleural curvilinear opacities, air bronchogram, and pleural thickening) of the patients were evaluated. CT ndings were also evaluated with the RSNA consensus guideline and the CORADS scoring system. Data were divided into two main groups-non-COVID-19 and COVID-19 pneumonia-and compared statistically with chi-squared tests and multiple regression analysis of independent variables. Results. RSNA and CORADS classi cations of CT scan images were able to successfully di erentiate between positive and negative COVID-19 pneumonia patients. Statistically signi cant di erences were found between the two patient groups in various categories including the percentage of involvement, number of lesions, distribution preference, dominant pattern, nodule, tree in bud, interstitial changes, crazy paving, reverse halo vascular enlargement, peribronchial wall thickness, air trapping, pleural retraction, pleural/pericardial e usion, cavitation, and mediastinal/hilar lymphadenopathy (p < 0.01). Multiple linear regression analysis of independent variables found a signi cant e ect in reverse halo sign (β 0.097, p < 0.05) and pleural e usion (β 10.631, p < 0.05) on COVID-19 pneumonia patients. Conclusion. e presence of reverse halo and absence of pleural e usion was found to be characteristic of COVID-19 pneumonia and therefore a reliable diagnostic tool to di erentiate it from non-COVID-19 pneumonia.
Tanısal ve Girişimsel Radyoloji (Yeni Adı: Dİagnostic & Intervent. Radiol), 2004
Turkiye Klinikleri Journal of Internal Medical Sciences, 2006
Clinical Imaging, 2021
We aimed to compare COVID-19 imaging findings of young adults (19-35 years of age) with those of ... more We aimed to compare COVID-19 imaging findings of young adults (19-35 years of age) with those of children (0-18 years) and to correlate imaging findings of young adults with their laboratory tests. Materials and methods: This retrospective study included Real Time-Polymerase Chain Reaction (RT-PCR) confirmed 130 young adults (mean age: 28.39 ± 4.77; 65 male, 65 female) and 36 children (mean age: 12.41 ± 4.51; 17 male, 19 female), between March and June 2020. COVID-19 related imaging findings on chest CT were examined in young adults and compared with children by the Mann-Whitney U, and Chi-square or Fisher's exact test. Laboratory examinations of young adults were assessed in terms of correlation with radiological findings by the Spearman's correlation analysis. Results: Bilateral multiple distributions (p = 0.014), subpleural involvement, and pleural thickening (p = 0.004), GGOs with internal consolidations were more frequent in adults (p = 0.009). Infiltrations were significantly larger than 20 mm in young adults (p = 0.011). The rates of feeding vessel sign, vascular enlargement, and halo sign were significantly higher in young adults (p < 0.003). Highly significant positive correlations were found between radiological and biochemical parameters. Conclusion: Distribution, size, and pattern of COVID-19 related imaging findings differed in children and young adults. Radiological findings were correlated with biochemical parameters but not with blood count results of young adults. ☆ The authors declare that they have all participated in the design, execution, and analysis of the paper, and they have approved the final version. Additionally, there are no conflicts of interest in connection with this paper, and the material described is not under publication or consideration for publication elsewhere. No financial support was taken during the paper was preparing.
Toraks Cerrahisi Bulteni, 2012
CardioVascular and Interventional Radiology, 2007
Discussion Unicuspid aortic valve is rare and often confused with bicuspid valve, which is a more... more Discussion Unicuspid aortic valve is rare and often confused with bicuspid valve, which is a more common congenital anomaly. In adults undergoing surgical intervention for aortic valve disease, unicuspid valve accounts for≤ 5% of the cases, whereas a bicuspid valve ...
American Journal of Roentgenology, 2006
Yekeler et al. Frequency of Sternal Variations and Anomalies M u s c u l o s ke l e t a l I m a g... more Yekeler et al. Frequency of Sternal Variations and Anomalies M u s c u l o s ke l e t a l I m a g i n g • C l i n i c a l O b s e r v a t i o n s
American Journal of Roentgenology, 1995
After its discovery by WC. Roentgen by the end of 1895, X-Rays were immediately used for medical ... more After its discovery by WC. Roentgen by the end of 1895, X-Rays were immediately used for medical and surgical purposes to detect foreign objects within the human body due to injuries and/or gunshots, which inspired discussions over its functionality in military surgery. X-Rays were first used in the beginning of 1896 at the British River Wars in Nile, Egypt. In May 1896, the Italian Doctor Guiseppe Alvaro took two wounded soldiers from Ethiopia to Italy and shot radiographies of them by making use of X-Rays in the Naples Military Hospital. He published his observations in Giornale Medico del Regio Esercito. Before Alvaro's piece, an article had been published in Medizinische Wohenschrift, on February 4, 1896 about the use of X-Rays on the wounded soldiers in the Prussian Army. However, the systematic practice of X-Rays use in the military dates to the Greco-Turkish War in 1897 by its implementation on the bodies of the casualties of war, first in Istanbul, and then in Athens by means of the radiographies showing evidence of pieces of bullet and shrapnel inside the bodies of soldiers. The first military radiographies were scientifically and systematically taken through a device set up by those two interns of the School of Medicine in Istanbul from May 1, 1897. That war was the first occasion that radiographic imaging techniques were used extensively on wounded soldiers at both fronts soon after the discovery of X-rays. This historic development is presented in this article by evidence based on the Ottoman Archival documents and on the newspapers published at that time. Rather than a competitive historiog-raphy, our paper has been dealt with mutual respect by objectively honouring professional zeal of all the physicians who took part at that fateful event, meritedly.
American Journal of Neuroradiology, 2002
Chronic abuse of toluene by inhalation causes variable white matter changes and thalamic hypointe... more Chronic abuse of toluene by inhalation causes variable white matter changes and thalamic hypointensity on T2-weighted MR images. The purpose of our study was to assess cranial MR findings in a large series of patients who chronically abuse toluene-containing solvents to investigate the factors causing the qualitative variability of white matter changes and thalamic hypointensity. We studied the neurologic signs, symptoms, and cranial MR findings in 41 patients who chronically abused thinner, a toluene-containing solvent. We classified white matter changes as diffuse or restricted. We tested the associations of the development of white matter lesions and thalamic hypointensity with patient age at onset of abuse and duration of abuse. MR images revealed white matter lesions in 46% of the patients, atrophic dilatation of ventricles and sulci in 27%, and thalamic hypointensity in 20%. White matter changes were restricted in 53% and diffuse in 47%. The development of white matter changes...
Turkiye Klinikleri Radiology - Special Topics, 2021
Radiology, Jun 1, 1996
To evaluate the usefulness of self-expanding nitinol stents in the palliative treatment of malign... more To evaluate the usefulness of self-expanding nitinol stents in the palliative treatment of malignant dysphagia. Eighty self-expanding nitinol stents were placed in 59 patients (43 men, 16 women; mean age, 55 years; age range, 23-75 years) with inoperable malignant stenosis due to squamous cell carcinoma of the esophagus (n = 36), adenocarcinoma (n = 19), invasion of the esophagus due to carcinoma of the lung (n = 2), and recurrent anastomotic carcinoma (n = 2). Dysphagia was graded on a scale of 0 to 3. Follow-up esophagograms were obtained to evaluate stent patency. Stent placement was successful in all patients. The severity of dysphagia decreased at least one grade in all but one patient. Tumor ingrowth and overgrowth were seen in 21 (36%) patients 2 days to 7 months after stent placement and caused recurrent dysphagia. These 21 patients underwent balloon dilation and additional stent placement. A mediastinal fistula was seen in three patients (5%), ulceration in four (7%), stent torsion in three (5%), and incomplete expansion of the stent in two (2%). Repeat intervention was necessary in 51% of the patients. There is a substantial range of drawbacks and complications associated with the use of self-expanding nitinol stents for palliation of malignant esophageal strictures. A covering would be necessary to prevent tumor ingrowth.
medRxiv (Cold Spring Harbor Laboratory), May 14, 2022
doi: medRxiv preprint NOTE: This preprint reports new research that has not been certified by pee... more doi: medRxiv preprint NOTE: This preprint reports new research that has not been certified by peer review and should not be used to guide clinical practice.
Canadian Journal of Infectious Diseases & Medical Microbiology, Sep 29, 2022
Background. orax computed tomography (CT) imaging is widely used as a diagnostic method in the di... more Background. orax computed tomography (CT) imaging is widely used as a diagnostic method in the diagnosis of coronavirus disease 2019 (COVID-19)-related pneumonia. Radiological di erential diagnosis and isolation of other viral agents causing pneumonia in patients have gained importance, particularly during the pandemic. Aims. We aimed to investigate whether there is a di erence between CT images from patients with COVID-19-associated pneumonia compared to CT images of patients with pneumonia due to other viral agents and which nding may be more e ective in diagnosis. Study Design. e study included 249 adult patients with pneumonia identi ed by thorax CT examination and with a positive COVID-19 RT-PCR test compared to 94 patients diagnosed with non-COVID-19 pneumonia (viral PCR positive but no bacterial or fungal agents detected in other cultures) between 2015 and 2019. CT images were retrospectively analyzed using the PACS system. CT ndings were evaluated by two radiologists with 5 and 20 years of experience, in a blinded fashion, and the outcome was decided by consensus. Methods. Demographic data (age, gender, and known chronic disease) and CT imaging ndings (percentage of involvement, number of lesions, distribution preference, dominant pattern, ground-glass opacity distribution pattern, nodule, tree in bud sign, interstitial changes, crazy paving sign, reversed halo sign, vacuolar sign, halo sign, vascular enlargement, linear opacities, traction bronchiectasis, peribronchial wall thickness, air trapping, pleural retraction, pleural e usion, pericardial e usion, cavitation, mediastinal/hilar lymphadenopathy, dominant lesion size, consolidation, subpleural curvilinear opacities, air bronchogram, and pleural thickening) of the patients were evaluated. CT ndings were also evaluated with the RSNA consensus guideline and the CORADS scoring system. Data were divided into two main groups-non-COVID-19 and COVID-19 pneumonia-and compared statistically with chi-squared tests and multiple regression analysis of independent variables. Results. RSNA and CORADS classi cations of CT scan images were able to successfully di erentiate between positive and negative COVID-19 pneumonia patients. Statistically signi cant di erences were found between the two patient groups in various categories including the percentage of involvement, number of lesions, distribution preference, dominant pattern, nodule, tree in bud, interstitial changes, crazy paving, reverse halo vascular enlargement, peribronchial wall thickness, air trapping, pleural retraction, pleural/pericardial e usion, cavitation, and mediastinal/hilar lymphadenopathy (p < 0.01). Multiple linear regression analysis of independent variables found a signi cant e ect in reverse halo sign (β 0.097, p < 0.05) and pleural e usion (β 10.631, p < 0.05) on COVID-19 pneumonia patients. Conclusion. e presence of reverse halo and absence of pleural e usion was found to be characteristic of COVID-19 pneumonia and therefore a reliable diagnostic tool to di erentiate it from non-COVID-19 pneumonia.
Tanısal ve Girişimsel Radyoloji (Yeni Adı: Dİagnostic & Intervent. Radiol), 2004
Turkiye Klinikleri Journal of Internal Medical Sciences, 2006
Clinical Imaging, 2021
We aimed to compare COVID-19 imaging findings of young adults (19-35 years of age) with those of ... more We aimed to compare COVID-19 imaging findings of young adults (19-35 years of age) with those of children (0-18 years) and to correlate imaging findings of young adults with their laboratory tests. Materials and methods: This retrospective study included Real Time-Polymerase Chain Reaction (RT-PCR) confirmed 130 young adults (mean age: 28.39 ± 4.77; 65 male, 65 female) and 36 children (mean age: 12.41 ± 4.51; 17 male, 19 female), between March and June 2020. COVID-19 related imaging findings on chest CT were examined in young adults and compared with children by the Mann-Whitney U, and Chi-square or Fisher's exact test. Laboratory examinations of young adults were assessed in terms of correlation with radiological findings by the Spearman's correlation analysis. Results: Bilateral multiple distributions (p = 0.014), subpleural involvement, and pleural thickening (p = 0.004), GGOs with internal consolidations were more frequent in adults (p = 0.009). Infiltrations were significantly larger than 20 mm in young adults (p = 0.011). The rates of feeding vessel sign, vascular enlargement, and halo sign were significantly higher in young adults (p < 0.003). Highly significant positive correlations were found between radiological and biochemical parameters. Conclusion: Distribution, size, and pattern of COVID-19 related imaging findings differed in children and young adults. Radiological findings were correlated with biochemical parameters but not with blood count results of young adults. ☆ The authors declare that they have all participated in the design, execution, and analysis of the paper, and they have approved the final version. Additionally, there are no conflicts of interest in connection with this paper, and the material described is not under publication or consideration for publication elsewhere. No financial support was taken during the paper was preparing.
Toraks Cerrahisi Bulteni, 2012
CardioVascular and Interventional Radiology, 2007
Discussion Unicuspid aortic valve is rare and often confused with bicuspid valve, which is a more... more Discussion Unicuspid aortic valve is rare and often confused with bicuspid valve, which is a more common congenital anomaly. In adults undergoing surgical intervention for aortic valve disease, unicuspid valve accounts for≤ 5% of the cases, whereas a bicuspid valve ...
American Journal of Roentgenology, 2006
Yekeler et al. Frequency of Sternal Variations and Anomalies M u s c u l o s ke l e t a l I m a g... more Yekeler et al. Frequency of Sternal Variations and Anomalies M u s c u l o s ke l e t a l I m a g i n g • C l i n i c a l O b s e r v a t i o n s
American Journal of Roentgenology, 1995
After its discovery by WC. Roentgen by the end of 1895, X-Rays were immediately used for medical ... more After its discovery by WC. Roentgen by the end of 1895, X-Rays were immediately used for medical and surgical purposes to detect foreign objects within the human body due to injuries and/or gunshots, which inspired discussions over its functionality in military surgery. X-Rays were first used in the beginning of 1896 at the British River Wars in Nile, Egypt. In May 1896, the Italian Doctor Guiseppe Alvaro took two wounded soldiers from Ethiopia to Italy and shot radiographies of them by making use of X-Rays in the Naples Military Hospital. He published his observations in Giornale Medico del Regio Esercito. Before Alvaro's piece, an article had been published in Medizinische Wohenschrift, on February 4, 1896 about the use of X-Rays on the wounded soldiers in the Prussian Army. However, the systematic practice of X-Rays use in the military dates to the Greco-Turkish War in 1897 by its implementation on the bodies of the casualties of war, first in Istanbul, and then in Athens by means of the radiographies showing evidence of pieces of bullet and shrapnel inside the bodies of soldiers. The first military radiographies were scientifically and systematically taken through a device set up by those two interns of the School of Medicine in Istanbul from May 1, 1897. That war was the first occasion that radiographic imaging techniques were used extensively on wounded soldiers at both fronts soon after the discovery of X-rays. This historic development is presented in this article by evidence based on the Ottoman Archival documents and on the newspapers published at that time. Rather than a competitive historiog-raphy, our paper has been dealt with mutual respect by objectively honouring professional zeal of all the physicians who took part at that fateful event, meritedly.
American Journal of Neuroradiology, 2002
Chronic abuse of toluene by inhalation causes variable white matter changes and thalamic hypointe... more Chronic abuse of toluene by inhalation causes variable white matter changes and thalamic hypointensity on T2-weighted MR images. The purpose of our study was to assess cranial MR findings in a large series of patients who chronically abuse toluene-containing solvents to investigate the factors causing the qualitative variability of white matter changes and thalamic hypointensity. We studied the neurologic signs, symptoms, and cranial MR findings in 41 patients who chronically abused thinner, a toluene-containing solvent. We classified white matter changes as diffuse or restricted. We tested the associations of the development of white matter lesions and thalamic hypointensity with patient age at onset of abuse and duration of abuse. MR images revealed white matter lesions in 46% of the patients, atrophic dilatation of ventricles and sulci in 27%, and thalamic hypointensity in 20%. White matter changes were restricted in 53% and diffuse in 47%. The development of white matter changes...