Atul R. Rukadikar - Academia.edu (original) (raw)

Papers by Atul R. Rukadikar

Research paper thumbnail of Effectiveness of yoga on Ewing's battery autonomic function test: cross-sectional study

PubMed, 2023

Introduction: The cardiovascular autonomic functions can be tested by a Battery of five tests dev... more Introduction: The cardiovascular autonomic functions can be tested by a Battery of five tests developed by Ewing and Clark in 1981 in Edinburgh. Yogic practices are immensely useful for physical, mental and spiritual development required for better autonomic function. Aim and objectives: To assess the ANS (Autonomic function system) function with help of Ewing's Battery tests in yoga participants and healthy participants not practicing yoga. Materials and methods: A cross-sectional study was conducted on 270 participants which were divided into two groups viz: 135 in healthy control (Group I) and 135 in yoga group (Group II). Subjects with informed consent between 40-50 years, were included in control (Group I) and those practicing yoga for past minimum 3 months were included in Group II. Anthropometric measurements were done and parasympathetic tests like Heart rate (HR) response to standing from the supine posture, to Valsalva maneuvers and to slow deep breathing were done. Also, sympathetic tests, Blood Pressure (BP) response to cold in cold pressor test (CPT), to sustained handgrip test and to standing from lying posture were carried out. Results: P value was found to be statically significant among yoga group as compared with healthy control group in all the sympathetic and parasympathetic tests except in CPT. As per the Ewing's criteria, normal, early, diseased and severe CAN (Cardiac autonomic neuropathy) in healthy controls findings were 11.11%, 58.51%, 37.03%, 17.77% and in yoga participants findings were 37.7%, 34.8%, 6.66% and 8.88% respectively. According to Bellavere's classification, maximum diseased CAN were found in healthy control as compared to yoga group. As per AIIMS (All India Institute of Medical Sciences) criteria, parasympathetic neuropathy was observed in 11.85% of the healthy controls and in 6.66% of the yoga group, and that maximum sympathetic neuropathy was observed in 11.11% of the healthy patients and only 3.7% of the yoga group. Conclusion: More emphasis should be given on implementation of yoga from early ages at the institutional levels, hospital levels. Yoga practices will suffice and lead to improvement of unhealthy ANS condition. Overall, Yoga showed better ANS function than healthy control group.

Research paper thumbnail of Blood Stream Infections and Its Antimicrobial Sensitivity in Tertiary Care Hospital, India

Book Publisher International (a part of SCIENCEDOMAIN International), Feb 14, 2021

Research paper thumbnail of Clinicomicrobial Profile of Neonatal Septicemia at a Tertiary Care Centre in Central India

International Journal of Current Microbiology and Applied Sciences, Dec 10, 2017

Neonatal septicemia is an important cause of morbidity and mortality among neonates constituting ... more Neonatal septicemia is an important cause of morbidity and mortality among neonates constituting about 30-50% of total neonatal deaths in developing countries. (1)(2) Data from National Neonatal Perinatal Database(NNPD, 2002-03) reveal that the incidence of neonatal sepsis is 30 per 1000 live births, (3) sepsis develops in 20% neonates and 1% approximately die of sepsis related causes. (2) Origin of Early onset sepsis (EOS) [within first week of life] is generally from pathogens of maternal genital tract, whereas late onset sepsis (LOS) [after first week till 28 days of life] is acquired either from the community or from hospital. (4) Blood culture has a great diagnostic and prognostic significance in diagnosis of

Research paper thumbnail of Aerobic bacterial profile of blood stream infections and its antimicrobial sensitivity pattern in tertiary care hospital

Indian Journal of Microbiology Research, Nov 15, 2017

Introduction: Blood stream infections cause significant disease and death worldwide and are among... more Introduction: Blood stream infections cause significant disease and death worldwide and are among the most common healthcare associated infections. Large numbers of cases of treatment failure are being reported due to emergence of drug resistance. Early microbiological diagnosis and determination of antimicrobial sensitivity pattern have been shown to improve treatment outcome. The present study was aimed to determine the bacterial and antimicrobial sensitivity pattern of blood stream infections in a major tertiary care hospital. Materials and Method: Prospective cross sectional study was carried out in the Department of Microbiology, People's College of Medical College and Research Centre, Bhopal from July 2015 to March 2016. Non repetitive blood samples of 647 clinically suspected patients of blood stream infection were collected and processed by standard methods. Isolation and identification of organisms was done as per standard guidelines. Results: Out of 647 blood culture samples, 106 (16.38%) were positive. The present study showed a predominance of Gram negative bacteremia (55.66%) over Gram positive bacteremia (44.34%). Conclusion: Appropriate treatment of blood stream infections should be based on the current knowledge of bacterial resistance pattern as provided by microbiology laboratory. This type of study will help in formulating management guidelines and antibiotic policy for effective management and proper antibiotic therapy in patients with bacteremia.

Research paper thumbnail of A study of the association between virulence factors and antifungal susceptibility profile of Candida species recovered from cases of vulvovaginal candidiasis

Journal of family medicine and primary care, 2023

Research paper thumbnail of Correlation of arm fat index and hand grip strength in cricket players: A cross-sectional study

Indian Journal of Clinical Anatomy and Physiology, 2017

Introduction: Hand grip strength and arm fat index has been an indicator for determining strength... more Introduction: Hand grip strength and arm fat index has been an indicator for determining strength. Objectives: The purpose of study was to found out correlation of hand grip strength with arm fat index in cricket players. Materials and Method: Total 30 healthy cricket players (15-25 years), from district sport academy, regularly practicing from last 3 years at university level and who don't have any abnormality of upper arm or any neurological problem, history of fracture of hand were included. Measurement of hand grip strength with help of Sahens hand grip digital dynamometer was done. Mean of three reading was taken as final reading. Arm fat index is calculated by formula, 100 x Mid upper arm fat area / mid upper arm area. Mid upper arm fat area determined by Mid upper arm muscle area and mid upper arm. Pearson correlation coefficient established a correlation of arm fat index with hand grip strength. Result: It was also found that statistically there was highly significant negative correlation observed between AFI and dominant handgrip strength in Cricket players (P < 0.01). Conclusion: Proper training for maintaining arm fat index will increase in hand grip strength. It will further lead to better strength and performance in cricket activities like bowling, throwing, fielding.

Research paper thumbnail of Pulmonary Tuberculosis, HIV, AIDS, CD4 counts

Research paper thumbnail of Interpretation of Antimicrobial Susceptibility Testing Using European Committee on Antimicrobial Susceptibility Testing (EUCAST) and Clinical and Laboratory Standards Institute (CLSI) Breakpoints: Analysis of Agreement

Cureus, Mar 31, 2023

Objectives: Breakpoints provided by European Committee on Antimicrobial Susceptibility Testing (E... more Objectives: Breakpoints provided by European Committee on Antimicrobial Susceptibility Testing (EUCAST) are now being used in many countries. This study was planned to ascertain the agreement in antimicrobial susceptibility using the Clinical and Laboratory Standards Institute (CLSI) and EUCAST breakpoints during the Kirby-Bauer disk diffusion method. Methods: This was a prospective observational study. Clinical isolates belonging to the family Enterobacteriaceae recovered between January and December, 2022, were included in the analysis. The diameter of the zone of inhibition of the 14 antimicrobials (viz. amoxicillin/clavulanic acid, cefazolin, ceftriaxone, cefuroxime, cefixime, aztreonam, meropenem, gentamicin, amikacin, ciprofloxacin, levofloxacin, norfloxacin, trimethoprim/sulfamethoxazole and fosfomycin) was analysed. Antimicrobial susceptibility was interpreted using CLSI 2022 and EUCAST 2022 guidelines. Results: Susceptibility data from a total of 356 isolates showed a slight increase in the percentage of resistant isolates with most of the drugs using EUCAST guidelines. The level of agreement varied from almost perfect to slight. For two drugs, i.e., fosfomycin and cefazolin, the agreement was least among the drug analysed (kappa (κ) value < 0.5, p < 0.001). For Ceftriaxone and Aztreonam, with EUCAST, susceptible (S) isolates would have been categorised in the newly redefined "I" category. It would have indicated the use of higher dosages of drugs. Conclusion: Change in the breakpoints impacts the interpretation of the susceptibility. It can also lead to a change in the dosage of the drug used for treatment. Therefore, there is an urgent need to see the impact of recent modifications "I" category of EUCAST on the clinical outcome and usage of antimicrobials.

Research paper thumbnail of Dengue, IgM, IgG, NS1, thrombocytopenia

Research paper thumbnail of Determination of Epidemiological Markers and Seroprevalence of Chlamydia Trachomatis in Female Sti Attendees

Book Publisher International (a part of SCIENCEDOMAIN International), Apr 9, 2022

Research paper thumbnail of Comparative Study of various anthropometric parameters in cricket and football players

European Journal of Molecular & Clinical Medicine, Feb 8, 2021

Background: Anthropometric scales express the physical potential of football players and can be u... more Background: Anthropometric scales express the physical potential of football players and can be used to compare them with other sports. Anthropometric proportions play a key role in cricket. Aims and Objectives: To comparison of various anthropometric parameters in cricket and football players. Material and Methods: The present research was carried out in the Sports Physiology Laboratory of the Department of Physiology. The period of the study from December 2012 to November 2014 and the form of study is not followed up. Test analysis is conducted to conduct a comparative study of anthropometric parameters in cricket and football players. Results: We did a test sample with 60 subjects (30 cricket players and 30 football players). The average value of the height of football players is more than that of cricketers. The average weight value of cricket players is higher than that of football players. BMI, percent body fat, percent lean body weight, mid-upper arm circumference, mid-upper arm area, corrected mid-upper arm muscle area, arm fat index, is substantially higher in Cricket players than in Football players. Conclusion: In our research, we notice that, in our cricket and football players, the majority of anthropometric parameters such as height, weight, percent lean body mass, mid-upper arm diameter, mid-upper arm area, and corrected mid-upper arm muscle area are lagging when compared to international cricketers and football players.

Research paper thumbnail of Study of bilateral HGS difference in DM and ND hand grip strength in Right-handed and Left-handed players

European Journal of Molecular & Clinical Medicine, Feb 8, 2021

Background: The handgrip dynamometry measure expresses the physical ability of the player and can... more Background: The handgrip dynamometry measure expresses the physical ability of the player and can be used for comparisons with other sports. Handgrip power plays a vital role in cricket. Aims and Objectives: To study and find out bilateral HGS difference in DM and ND handgrip strength in Right-handed and Left-handed players. Material and Methods: A study was done by sampling 60 players of 50 players righthanded and 10 players of left-handed were recruited after screening for inclusion and exclusion criteria. All participants were tested for their handgrip ability using a handheld dynamometer. Results: The results of the present study showed Bilateral HGS difference of Right-handed players is 7.50% (less than 10%) and the Bilateral HGS difference of Left-handed players is 5.35% (less than 10%). Conclusion: We concluded that the Dominant handgrip strength (DM HGS) of players is higher than nondominant handgrip strength (NDM HGS) in both Right-handed and Lefthanded players.

Research paper thumbnail of A Review on Autonomic Functional Assessment in Diabetic Patients

Cureus, Feb 3, 2023

In today's world, science has progressed significantly, yet most people are still unaware of diab... more In today's world, science has progressed significantly, yet most people are still unaware of diabetes. Lack of obesity, physical work, and lifestyle changes are the main factors. Diabetes is becoming more common all around the globe. Type 2 diabetes may go unnoticed for years, resulting in serious consequences and high healthcare expenses. The goal of this study is to look at a wide range of studies in which the autonomic function of diabetic people has been studied with the help of various autonomic function tests (AFTs). AFT is a non-invasive approach to assessing patients for testing sympathetic and parasympathetic responses to stimuli. AFT findings give us comprehensive knowledge of the autonomic physiology reactions in normal and in autonomic diseases like diabetes. This review will concentrate on AFTs that are scientifically valid, trustworthy, and clinically beneficial, according to experts.

Research paper thumbnail of A Review on Autonomic Functional Assessment in Diabetic Patients

Cureus

In today's world, science has progressed significantly, yet most people are still unaware of diab... more In today's world, science has progressed significantly, yet most people are still unaware of diabetes. Lack of obesity, physical work, and lifestyle changes are the main factors. Diabetes is becoming more common all around the globe. Type 2 diabetes may go unnoticed for years, resulting in serious consequences and high healthcare expenses. The goal of this study is to look at a wide range of studies in which the autonomic function of diabetic people has been studied with the help of various autonomic function tests (AFTs). AFT is a non-invasive approach to assessing patients for testing sympathetic and parasympathetic responses to stimuli. AFT findings give us comprehensive knowledge of the autonomic physiology reactions in normal and in autonomic diseases like diabetes. This review will concentrate on AFTs that are scientifically valid, trustworthy, and clinically beneficial, according to experts.

Research paper thumbnail of Effect of body mass index on cardiorespiratory parameters among medical students: a cross-sectional study

International journal of physiology, pathophysiology and pharmacology, 2022

BACKGROUND Obesity is a global crisis due to its significant contribution to mortality and morbid... more BACKGROUND Obesity is a global crisis due to its significant contribution to mortality and morbidity. This study discovered an association between body mass index (BMI) with pulmonary function tests (PFTs) and aerobic capacity (VO2 max) in medical students of Zydus Medical College and Hospital, Dahod, Gujarat. AIM The study aimed to determine the effect of obesity on cardiopulmonary health of medical students. OBJECTIVES The study objectives were as follows: 1. To compare PFT parameters and VO2 max between obese and non-obese students. 2. To study the correlation of BMI with PFTs and VO2 max. MATERIAL AND METHODS BMI was calculated with the formula BMI = weight/height2. PFTs were assessed with computerized spirometry. Aerobic capacity was calculated with Astrand 6-minute Cycle Test. Statistical analysis was done with unpaired t-test. RESULTS This study found a significant difference in forced vital capacity (FVC), forced expiratory volume in 1 minute (FEV1), slow vital capacity (SVC), maximum ventilatory volume (MVV), and VO2 max between obese and non-obese students (P<0.05). There was a positive correlation between BMI and forced mid-expiratory flow (FEF25-75), peak expiratory flow rate (PEFR), MVV, SVC, expiratory reserve volume (ERV), and MVV and negative correlation with FVC, FEV1, lung age, and VO2 max in non-obese students. There was also a positive correlation between BMI and PEFR, SVC, FVC, FEV1, lung age, MVV, ERV, and a negative correlation with FEF25-75 and VO2 max in obese students. CONCLUSION As BMI is inversely related to cardiopulmonary function, students having high BMI can be motivated toward a healthy lifestyle.

Research paper thumbnail of Study of effect of yoga on blood pressure, blood glucose, and glycosylated hemoglobin levels of patients with Type 2 diabetes mellitus

National Journal of Physiology, Pharmacy and Pharmacology

Background: India is known as the diabetic capital of the world. Yoga induces relaxation, which i... more Background: India is known as the diabetic capital of the world. Yoga induces relaxation, which is also a crucial factor in the healthy functioning of the internal organs of the body. It can help to maintain normal BSL. Aims and Objectives: This study was planned to assess and compare the effect of yoga on BP, fasting blood glucose, and Glycosylated hemoglobin (HbA1C) level before and after the intervention (Yoga) in patients of Type 2 diabetes mellitus (T2DM). Materials and Methods: Current research has been conducted in collaboration with the Department of Medicine, Department of Pathology, and Department of Biochemistry, Department of Physiology, Jhalawar Medical College and Hospital, Jhalawar (Rajasthan) and Yoga OPD. A randomized, controlled study is currently underway. The test group consisted of 50 subjects with a control group of 50 subjects. The goal of this research was to examine the 3-month effect of yoga practice on subjects with T2DM. Results: In the current study, differences in blood pressure between cases and controls were not relevant in terms of height, whereas mean fasting glucose levels, HbA1C, and body mass index were found to be significantly lower in the yoga-medication study community relative to controls who took only non-yogapractice drugs. Conclusion: Yogic practices play a role in both primary and secondary prevention of DM. Yoga therapy can also be considered to be a beneficial adjuvant in the treatment of T2DM.

Research paper thumbnail of Determination of Epidemiological Markers and Seroprevalence of Chlamydia Trachomatis in Female Sti Attendees

New Horizons in Medicine and Medical Research Vol. 6

Research paper thumbnail of Study of opportunistic infections in HIV-AIDS patients and their co-relation with CD4+ cell count

International Journal of Current Microbiology and Applied Sciences, 2015

Opportunistic infections are the manifestations caused by the pathogens which are usually not inv... more Opportunistic infections are the manifestations caused by the pathogens which are usually not invasive but invade the body when its immunity is hampered because of one or the other reasons. It occurs in conditions like AIDS, various malignancies, steroid therapy, radiotherapy and diabetes. With the changing scenario of AIDS epidemic, a host of opportunistic infections add to the present endemic state of some already existing infections like tuberculosis .Opportunistic infections ISSN: 2319-7706 Volume 4 Number 6 (2015) pp. 848-861 http://www.ijcmas.com

Research paper thumbnail of Study of bilateral HGS difference in DM and ND hand grip strength in Right-handed and Left-handed players

Background: The handgrip dynamometry measure expresses the physical ability of the player and can... more Background: The handgrip dynamometry measure expresses the physical ability of the player and can be used for comparisons with other sports. Handgrip power plays a vital role in cricket. Aims and Objectives: To study and find out bilateral HGS difference in DM and ND handgrip strength in Right-handed and Left-handed players. Material and Methods: A study was done by sampling 60 players of 50 players righthanded and 10 players of left-handed were recruited after screening for inclusion and exclusion criteria. All participants were tested for their handgrip ability using a handheld dynamometer. Results: The results of the present study showed Bilateral HGS difference of Right-handed players is 7.50% (less than 10%) and the Bilateral HGS difference of Left-handed players is 5.35% (less than 10%). Conclusion: We concluded that the Dominant handgrip strength (DM HGS) of players is higher than nondominant handgrip strength (NDM HGS) in both Right-handed and Lefthanded players.

Research paper thumbnail of Comparative Study of various anthropometric parameters in cricket and football players

Background: Anthropometric scales express the physical potential of football players and can be u... more Background: Anthropometric scales express the physical potential of football players and can be used to compare them with other sports. Anthropometric proportions play a key role in cricket. Aims and Objectives: To comparison of various anthropometric parameters in cricket and football players. Material and Methods: The present research was carried out in the Sports Physiology Laboratory of the Department of Physiology. The period of the study from December 2012 to November 2014 and the form of study is not followed up. Test analysis is conducted to conduct a comparative study of anthropometric parameters in cricket and football players. Results: We did a test sample with 60 subjects (30 cricket players and 30 football players). The average value of the height of football players is more than that of cricketers. The average weight value of cricket players is higher than that of football players. BMI, percent body fat, percent lean body weight, mid-upper arm circumference, mid-upper ...

Research paper thumbnail of Effectiveness of yoga on Ewing's battery autonomic function test: cross-sectional study

PubMed, 2023

Introduction: The cardiovascular autonomic functions can be tested by a Battery of five tests dev... more Introduction: The cardiovascular autonomic functions can be tested by a Battery of five tests developed by Ewing and Clark in 1981 in Edinburgh. Yogic practices are immensely useful for physical, mental and spiritual development required for better autonomic function. Aim and objectives: To assess the ANS (Autonomic function system) function with help of Ewing's Battery tests in yoga participants and healthy participants not practicing yoga. Materials and methods: A cross-sectional study was conducted on 270 participants which were divided into two groups viz: 135 in healthy control (Group I) and 135 in yoga group (Group II). Subjects with informed consent between 40-50 years, were included in control (Group I) and those practicing yoga for past minimum 3 months were included in Group II. Anthropometric measurements were done and parasympathetic tests like Heart rate (HR) response to standing from the supine posture, to Valsalva maneuvers and to slow deep breathing were done. Also, sympathetic tests, Blood Pressure (BP) response to cold in cold pressor test (CPT), to sustained handgrip test and to standing from lying posture were carried out. Results: P value was found to be statically significant among yoga group as compared with healthy control group in all the sympathetic and parasympathetic tests except in CPT. As per the Ewing's criteria, normal, early, diseased and severe CAN (Cardiac autonomic neuropathy) in healthy controls findings were 11.11%, 58.51%, 37.03%, 17.77% and in yoga participants findings were 37.7%, 34.8%, 6.66% and 8.88% respectively. According to Bellavere's classification, maximum diseased CAN were found in healthy control as compared to yoga group. As per AIIMS (All India Institute of Medical Sciences) criteria, parasympathetic neuropathy was observed in 11.85% of the healthy controls and in 6.66% of the yoga group, and that maximum sympathetic neuropathy was observed in 11.11% of the healthy patients and only 3.7% of the yoga group. Conclusion: More emphasis should be given on implementation of yoga from early ages at the institutional levels, hospital levels. Yoga practices will suffice and lead to improvement of unhealthy ANS condition. Overall, Yoga showed better ANS function than healthy control group.

Research paper thumbnail of Blood Stream Infections and Its Antimicrobial Sensitivity in Tertiary Care Hospital, India

Book Publisher International (a part of SCIENCEDOMAIN International), Feb 14, 2021

Research paper thumbnail of Clinicomicrobial Profile of Neonatal Septicemia at a Tertiary Care Centre in Central India

International Journal of Current Microbiology and Applied Sciences, Dec 10, 2017

Neonatal septicemia is an important cause of morbidity and mortality among neonates constituting ... more Neonatal septicemia is an important cause of morbidity and mortality among neonates constituting about 30-50% of total neonatal deaths in developing countries. (1)(2) Data from National Neonatal Perinatal Database(NNPD, 2002-03) reveal that the incidence of neonatal sepsis is 30 per 1000 live births, (3) sepsis develops in 20% neonates and 1% approximately die of sepsis related causes. (2) Origin of Early onset sepsis (EOS) [within first week of life] is generally from pathogens of maternal genital tract, whereas late onset sepsis (LOS) [after first week till 28 days of life] is acquired either from the community or from hospital. (4) Blood culture has a great diagnostic and prognostic significance in diagnosis of

Research paper thumbnail of Aerobic bacterial profile of blood stream infections and its antimicrobial sensitivity pattern in tertiary care hospital

Indian Journal of Microbiology Research, Nov 15, 2017

Introduction: Blood stream infections cause significant disease and death worldwide and are among... more Introduction: Blood stream infections cause significant disease and death worldwide and are among the most common healthcare associated infections. Large numbers of cases of treatment failure are being reported due to emergence of drug resistance. Early microbiological diagnosis and determination of antimicrobial sensitivity pattern have been shown to improve treatment outcome. The present study was aimed to determine the bacterial and antimicrobial sensitivity pattern of blood stream infections in a major tertiary care hospital. Materials and Method: Prospective cross sectional study was carried out in the Department of Microbiology, People's College of Medical College and Research Centre, Bhopal from July 2015 to March 2016. Non repetitive blood samples of 647 clinically suspected patients of blood stream infection were collected and processed by standard methods. Isolation and identification of organisms was done as per standard guidelines. Results: Out of 647 blood culture samples, 106 (16.38%) were positive. The present study showed a predominance of Gram negative bacteremia (55.66%) over Gram positive bacteremia (44.34%). Conclusion: Appropriate treatment of blood stream infections should be based on the current knowledge of bacterial resistance pattern as provided by microbiology laboratory. This type of study will help in formulating management guidelines and antibiotic policy for effective management and proper antibiotic therapy in patients with bacteremia.

Research paper thumbnail of A study of the association between virulence factors and antifungal susceptibility profile of Candida species recovered from cases of vulvovaginal candidiasis

Journal of family medicine and primary care, 2023

Research paper thumbnail of Correlation of arm fat index and hand grip strength in cricket players: A cross-sectional study

Indian Journal of Clinical Anatomy and Physiology, 2017

Introduction: Hand grip strength and arm fat index has been an indicator for determining strength... more Introduction: Hand grip strength and arm fat index has been an indicator for determining strength. Objectives: The purpose of study was to found out correlation of hand grip strength with arm fat index in cricket players. Materials and Method: Total 30 healthy cricket players (15-25 years), from district sport academy, regularly practicing from last 3 years at university level and who don't have any abnormality of upper arm or any neurological problem, history of fracture of hand were included. Measurement of hand grip strength with help of Sahens hand grip digital dynamometer was done. Mean of three reading was taken as final reading. Arm fat index is calculated by formula, 100 x Mid upper arm fat area / mid upper arm area. Mid upper arm fat area determined by Mid upper arm muscle area and mid upper arm. Pearson correlation coefficient established a correlation of arm fat index with hand grip strength. Result: It was also found that statistically there was highly significant negative correlation observed between AFI and dominant handgrip strength in Cricket players (P < 0.01). Conclusion: Proper training for maintaining arm fat index will increase in hand grip strength. It will further lead to better strength and performance in cricket activities like bowling, throwing, fielding.

Research paper thumbnail of Pulmonary Tuberculosis, HIV, AIDS, CD4 counts

Research paper thumbnail of Interpretation of Antimicrobial Susceptibility Testing Using European Committee on Antimicrobial Susceptibility Testing (EUCAST) and Clinical and Laboratory Standards Institute (CLSI) Breakpoints: Analysis of Agreement

Cureus, Mar 31, 2023

Objectives: Breakpoints provided by European Committee on Antimicrobial Susceptibility Testing (E... more Objectives: Breakpoints provided by European Committee on Antimicrobial Susceptibility Testing (EUCAST) are now being used in many countries. This study was planned to ascertain the agreement in antimicrobial susceptibility using the Clinical and Laboratory Standards Institute (CLSI) and EUCAST breakpoints during the Kirby-Bauer disk diffusion method. Methods: This was a prospective observational study. Clinical isolates belonging to the family Enterobacteriaceae recovered between January and December, 2022, were included in the analysis. The diameter of the zone of inhibition of the 14 antimicrobials (viz. amoxicillin/clavulanic acid, cefazolin, ceftriaxone, cefuroxime, cefixime, aztreonam, meropenem, gentamicin, amikacin, ciprofloxacin, levofloxacin, norfloxacin, trimethoprim/sulfamethoxazole and fosfomycin) was analysed. Antimicrobial susceptibility was interpreted using CLSI 2022 and EUCAST 2022 guidelines. Results: Susceptibility data from a total of 356 isolates showed a slight increase in the percentage of resistant isolates with most of the drugs using EUCAST guidelines. The level of agreement varied from almost perfect to slight. For two drugs, i.e., fosfomycin and cefazolin, the agreement was least among the drug analysed (kappa (κ) value < 0.5, p < 0.001). For Ceftriaxone and Aztreonam, with EUCAST, susceptible (S) isolates would have been categorised in the newly redefined "I" category. It would have indicated the use of higher dosages of drugs. Conclusion: Change in the breakpoints impacts the interpretation of the susceptibility. It can also lead to a change in the dosage of the drug used for treatment. Therefore, there is an urgent need to see the impact of recent modifications "I" category of EUCAST on the clinical outcome and usage of antimicrobials.

Research paper thumbnail of Dengue, IgM, IgG, NS1, thrombocytopenia

Research paper thumbnail of Determination of Epidemiological Markers and Seroprevalence of Chlamydia Trachomatis in Female Sti Attendees

Book Publisher International (a part of SCIENCEDOMAIN International), Apr 9, 2022

Research paper thumbnail of Comparative Study of various anthropometric parameters in cricket and football players

European Journal of Molecular & Clinical Medicine, Feb 8, 2021

Background: Anthropometric scales express the physical potential of football players and can be u... more Background: Anthropometric scales express the physical potential of football players and can be used to compare them with other sports. Anthropometric proportions play a key role in cricket. Aims and Objectives: To comparison of various anthropometric parameters in cricket and football players. Material and Methods: The present research was carried out in the Sports Physiology Laboratory of the Department of Physiology. The period of the study from December 2012 to November 2014 and the form of study is not followed up. Test analysis is conducted to conduct a comparative study of anthropometric parameters in cricket and football players. Results: We did a test sample with 60 subjects (30 cricket players and 30 football players). The average value of the height of football players is more than that of cricketers. The average weight value of cricket players is higher than that of football players. BMI, percent body fat, percent lean body weight, mid-upper arm circumference, mid-upper arm area, corrected mid-upper arm muscle area, arm fat index, is substantially higher in Cricket players than in Football players. Conclusion: In our research, we notice that, in our cricket and football players, the majority of anthropometric parameters such as height, weight, percent lean body mass, mid-upper arm diameter, mid-upper arm area, and corrected mid-upper arm muscle area are lagging when compared to international cricketers and football players.

Research paper thumbnail of Study of bilateral HGS difference in DM and ND hand grip strength in Right-handed and Left-handed players

European Journal of Molecular & Clinical Medicine, Feb 8, 2021

Background: The handgrip dynamometry measure expresses the physical ability of the player and can... more Background: The handgrip dynamometry measure expresses the physical ability of the player and can be used for comparisons with other sports. Handgrip power plays a vital role in cricket. Aims and Objectives: To study and find out bilateral HGS difference in DM and ND handgrip strength in Right-handed and Left-handed players. Material and Methods: A study was done by sampling 60 players of 50 players righthanded and 10 players of left-handed were recruited after screening for inclusion and exclusion criteria. All participants were tested for their handgrip ability using a handheld dynamometer. Results: The results of the present study showed Bilateral HGS difference of Right-handed players is 7.50% (less than 10%) and the Bilateral HGS difference of Left-handed players is 5.35% (less than 10%). Conclusion: We concluded that the Dominant handgrip strength (DM HGS) of players is higher than nondominant handgrip strength (NDM HGS) in both Right-handed and Lefthanded players.

Research paper thumbnail of A Review on Autonomic Functional Assessment in Diabetic Patients

Cureus, Feb 3, 2023

In today's world, science has progressed significantly, yet most people are still unaware of diab... more In today's world, science has progressed significantly, yet most people are still unaware of diabetes. Lack of obesity, physical work, and lifestyle changes are the main factors. Diabetes is becoming more common all around the globe. Type 2 diabetes may go unnoticed for years, resulting in serious consequences and high healthcare expenses. The goal of this study is to look at a wide range of studies in which the autonomic function of diabetic people has been studied with the help of various autonomic function tests (AFTs). AFT is a non-invasive approach to assessing patients for testing sympathetic and parasympathetic responses to stimuli. AFT findings give us comprehensive knowledge of the autonomic physiology reactions in normal and in autonomic diseases like diabetes. This review will concentrate on AFTs that are scientifically valid, trustworthy, and clinically beneficial, according to experts.

Research paper thumbnail of A Review on Autonomic Functional Assessment in Diabetic Patients

Cureus

In today's world, science has progressed significantly, yet most people are still unaware of diab... more In today's world, science has progressed significantly, yet most people are still unaware of diabetes. Lack of obesity, physical work, and lifestyle changes are the main factors. Diabetes is becoming more common all around the globe. Type 2 diabetes may go unnoticed for years, resulting in serious consequences and high healthcare expenses. The goal of this study is to look at a wide range of studies in which the autonomic function of diabetic people has been studied with the help of various autonomic function tests (AFTs). AFT is a non-invasive approach to assessing patients for testing sympathetic and parasympathetic responses to stimuli. AFT findings give us comprehensive knowledge of the autonomic physiology reactions in normal and in autonomic diseases like diabetes. This review will concentrate on AFTs that are scientifically valid, trustworthy, and clinically beneficial, according to experts.

Research paper thumbnail of Effect of body mass index on cardiorespiratory parameters among medical students: a cross-sectional study

International journal of physiology, pathophysiology and pharmacology, 2022

BACKGROUND Obesity is a global crisis due to its significant contribution to mortality and morbid... more BACKGROUND Obesity is a global crisis due to its significant contribution to mortality and morbidity. This study discovered an association between body mass index (BMI) with pulmonary function tests (PFTs) and aerobic capacity (VO2 max) in medical students of Zydus Medical College and Hospital, Dahod, Gujarat. AIM The study aimed to determine the effect of obesity on cardiopulmonary health of medical students. OBJECTIVES The study objectives were as follows: 1. To compare PFT parameters and VO2 max between obese and non-obese students. 2. To study the correlation of BMI with PFTs and VO2 max. MATERIAL AND METHODS BMI was calculated with the formula BMI = weight/height2. PFTs were assessed with computerized spirometry. Aerobic capacity was calculated with Astrand 6-minute Cycle Test. Statistical analysis was done with unpaired t-test. RESULTS This study found a significant difference in forced vital capacity (FVC), forced expiratory volume in 1 minute (FEV1), slow vital capacity (SVC), maximum ventilatory volume (MVV), and VO2 max between obese and non-obese students (P<0.05). There was a positive correlation between BMI and forced mid-expiratory flow (FEF25-75), peak expiratory flow rate (PEFR), MVV, SVC, expiratory reserve volume (ERV), and MVV and negative correlation with FVC, FEV1, lung age, and VO2 max in non-obese students. There was also a positive correlation between BMI and PEFR, SVC, FVC, FEV1, lung age, MVV, ERV, and a negative correlation with FEF25-75 and VO2 max in obese students. CONCLUSION As BMI is inversely related to cardiopulmonary function, students having high BMI can be motivated toward a healthy lifestyle.

Research paper thumbnail of Study of effect of yoga on blood pressure, blood glucose, and glycosylated hemoglobin levels of patients with Type 2 diabetes mellitus

National Journal of Physiology, Pharmacy and Pharmacology

Background: India is known as the diabetic capital of the world. Yoga induces relaxation, which i... more Background: India is known as the diabetic capital of the world. Yoga induces relaxation, which is also a crucial factor in the healthy functioning of the internal organs of the body. It can help to maintain normal BSL. Aims and Objectives: This study was planned to assess and compare the effect of yoga on BP, fasting blood glucose, and Glycosylated hemoglobin (HbA1C) level before and after the intervention (Yoga) in patients of Type 2 diabetes mellitus (T2DM). Materials and Methods: Current research has been conducted in collaboration with the Department of Medicine, Department of Pathology, and Department of Biochemistry, Department of Physiology, Jhalawar Medical College and Hospital, Jhalawar (Rajasthan) and Yoga OPD. A randomized, controlled study is currently underway. The test group consisted of 50 subjects with a control group of 50 subjects. The goal of this research was to examine the 3-month effect of yoga practice on subjects with T2DM. Results: In the current study, differences in blood pressure between cases and controls were not relevant in terms of height, whereas mean fasting glucose levels, HbA1C, and body mass index were found to be significantly lower in the yoga-medication study community relative to controls who took only non-yogapractice drugs. Conclusion: Yogic practices play a role in both primary and secondary prevention of DM. Yoga therapy can also be considered to be a beneficial adjuvant in the treatment of T2DM.

Research paper thumbnail of Determination of Epidemiological Markers and Seroprevalence of Chlamydia Trachomatis in Female Sti Attendees

New Horizons in Medicine and Medical Research Vol. 6

Research paper thumbnail of Study of opportunistic infections in HIV-AIDS patients and their co-relation with CD4+ cell count

International Journal of Current Microbiology and Applied Sciences, 2015

Opportunistic infections are the manifestations caused by the pathogens which are usually not inv... more Opportunistic infections are the manifestations caused by the pathogens which are usually not invasive but invade the body when its immunity is hampered because of one or the other reasons. It occurs in conditions like AIDS, various malignancies, steroid therapy, radiotherapy and diabetes. With the changing scenario of AIDS epidemic, a host of opportunistic infections add to the present endemic state of some already existing infections like tuberculosis .Opportunistic infections ISSN: 2319-7706 Volume 4 Number 6 (2015) pp. 848-861 http://www.ijcmas.com

Research paper thumbnail of Study of bilateral HGS difference in DM and ND hand grip strength in Right-handed and Left-handed players

Background: The handgrip dynamometry measure expresses the physical ability of the player and can... more Background: The handgrip dynamometry measure expresses the physical ability of the player and can be used for comparisons with other sports. Handgrip power plays a vital role in cricket. Aims and Objectives: To study and find out bilateral HGS difference in DM and ND handgrip strength in Right-handed and Left-handed players. Material and Methods: A study was done by sampling 60 players of 50 players righthanded and 10 players of left-handed were recruited after screening for inclusion and exclusion criteria. All participants were tested for their handgrip ability using a handheld dynamometer. Results: The results of the present study showed Bilateral HGS difference of Right-handed players is 7.50% (less than 10%) and the Bilateral HGS difference of Left-handed players is 5.35% (less than 10%). Conclusion: We concluded that the Dominant handgrip strength (DM HGS) of players is higher than nondominant handgrip strength (NDM HGS) in both Right-handed and Lefthanded players.

Research paper thumbnail of Comparative Study of various anthropometric parameters in cricket and football players

Background: Anthropometric scales express the physical potential of football players and can be u... more Background: Anthropometric scales express the physical potential of football players and can be used to compare them with other sports. Anthropometric proportions play a key role in cricket. Aims and Objectives: To comparison of various anthropometric parameters in cricket and football players. Material and Methods: The present research was carried out in the Sports Physiology Laboratory of the Department of Physiology. The period of the study from December 2012 to November 2014 and the form of study is not followed up. Test analysis is conducted to conduct a comparative study of anthropometric parameters in cricket and football players. Results: We did a test sample with 60 subjects (30 cricket players and 30 football players). The average value of the height of football players is more than that of cricketers. The average weight value of cricket players is higher than that of football players. BMI, percent body fat, percent lean body weight, mid-upper arm circumference, mid-upper ...