BADII AMAMOU - Academia.edu (original) (raw)
Papers by BADII AMAMOU
Frontiers in psychology, Apr 2, 2024
Journal of internal medicine. Science & art, Apr 8, 2024
Annales D Endocrinologie, Sep 1, 2020
Background: Acute myocardial infarction (AMI) is a recognized complication in patients with hyper... more Background: Acute myocardial infarction (AMI) is a recognized complication in patients with hypertrophic cardiomyopathy (HCM). However, there are limited data on outcomes of HCM patients presenting with AMI. methods: We queried the 2003-2011 Nationwide Inpatient Sample databases to identify all patients ≥18 years with the primary diagnosis of AMI. Patients with HCM were then identified using ICD-9-CM code 425.1. Logistic regression was used to compare treatment choice and outcomes in AMI patients with and without HCM. results: From 2003-2011, of 5,900,949 patients with AMI, 5,688 (0.1%) had a diagnosis of HCM. Patients with HCM were more likely to be older (71.4±13.9 years vs 67.8±14.5 years) and women (67.7% vs 40.2%). HCM patients were less likely to have traditional cardiovascular risk factors, including family history of coronary artery disease, dyslipidemia, obesity, smoking and diabetes mellitus. They were more likely to have congestive heart failure, atrial fibrillation, valvular diseases and prior history of cardiac arrest. HCM patients were less likely to have ST-elevation myocardial infarction (STEMI) (22.8% vs 37.5%, p<0.001). HCM patients with STEMI were less likely to receive thrombolysis (1.2% vs 3.8%, p<0.001) or percutaneous coronary intervention (PCI) (31.2% vs 56.8%, p<0.001). HCM patients with non-ST elevation myocardial infarction (NSTEMI) were less likely to receive PCI (14.9% vs 30.8%, p<0.001) or coronary artery bypass surgery (4.7% vs 9.6%, p<0.001). Among patients with STEMI, patients with HCM had 24% lower in-hospital mortality than patients without HCM (adjusted OR 0.76, 95 % CI 0.63-0.91, p=0.004). After further adjustment for treatment received, HCM patients with STEMI had 33% lower in-hospital mortality than patients without HCM (adjusted OR 0.67, 95% CI 0.55-0.80, p<0.001). Among patients with NSTEMI, there was no difference in in-hospital mortality in patients with and without HCM (p=0.91) (interaction p value for HCM and STEMI = 0.039). conclusion: HCM patients represent a small portion of patients with AMI and are less likely to be treated with revascularization. Compared to patients without HCM, HCM patients with STEMI have lower in-hospital mortality.
PubMed, 2014
Background: Stress is a part of the nursing profession and it is reflected in higher rates of dep... more Background: Stress is a part of the nursing profession and it is reflected in higher rates of depression and anxiety disorders. aim : This study aimed to determine the prevalence of major depression episodes (MDE), Dysthymia and generalized anxiety disorder (GAD), as well as their associated factors, in a representative sample of nurses in Sousse Farhat Hached teaching hospital, using the Tunisian version of CIDI. Methods: It's a descriptive study, carried out among a representative sample of the nursing staff of Sousse Farhat Hached teaching hospital (N=228). The data obtained was the result of an interview using the CIDI sections related to MDD, dysthymia and GAD. Sociodemographic, medical and professional data were also collected. Results: The MDE prevalence was estimated at 7.5% and was associated with the female gender, the remoteness of the workplace, the number of persons on the participant's charge, the personal antecedents of mental and organic pathologies, the job satisfaction related to internal relationships and security as well as with the wish to change position. The prevalence of Dysthymia was 5.7% and was associated with family antecedents of mental pathologies. The prevalence of TAG (4.4%) was associated with remoteness of the workplace, personal antecedents of mental pathologies and with satisfaction related to material conditions. Conclusion: The important issues of human and financial consequences of stress at work require the use of large-scale measures that should be incorporated into a strategy covering all factors and involving both health authorities and administrative occupational medicine.
European Neuropsychopharmacology, 2014
P.3.f. Psychotic disorders and treatment − Other (clinical) species (ROS) was accumulated in bloo... more P.3.f. Psychotic disorders and treatment − Other (clinical) species (ROS) was accumulated in blood. We suggest that the appearance of catalase activity in abzymes associated with compensation reduce erythrocyte catalase activity influenced by neuroleptic treatment. Conclusion: Probably, abzymes with catalase-like activity in patients with schizophrenia reduce the level of oxidative stress in blood. Obtained data will help to clarify role of IgG with catalase activities in protection against ROS in schizophrenia but this question requires further investigations. P.3.f. Psychotic disorders and treatment − Other (clinical) P.3.f.001 Impact of side effects of psychotropic drugs on the quality of life of patients with bipolar disorder
PubMed, Apr 1, 2013
Background: Major depression is a mental disorder that is associated with high morbidity and sign... more Background: Major depression is a mental disorder that is associated with high morbidity and significant mortality. It is common among primary care attenders. Few is known about major depression prevalence and associated factors, which would prevent general practitioners from diagnosing it in primary care centres and treating it adequately. Aim: To determine prevalence and correlates of major depressive episodes (MDE) in a representative sample of primary care attenders in the area of Sousse (Tunisia). Methods: A random and representative sample of primary care attenders was obtained by a two-stage sampling procedure. First, 30 primary care centres (20 urban and 10 rural) were selected, with stratification according to residency location. Second, 1246 consenting participants were systematically recruited among those centres attenders. Participants were screened, by trained interviewers, with Tunisian version of « Composite International Diagnostic Interview » CIDI.2.1. After data entry in ishell program, MDE diagnosis was obtained according to ICD-10 criteria. Results: Mean age in our sample was 43.4 ± 17.62 years, with feminine (70.9 %) and urban (67.8 %) predominance. MDE was found in 26.4 % of participants. Associated factors were female gender, marital statute of widowed or divorced and rural residency. Conclusion: This study provided data about high prevalence of MDE in the area of Sousse primary care centres and its correlated factors.
World Journal of Psychiatry
International Journal of Social Psychiatry, Feb 11, 2022
Background: Mental health-related stigma is a serious problem that has undesirable consequences f... more Background: Mental health-related stigma is a serious problem that has undesirable consequences for individuals with mental disorders including physical health disparities, increasing mortality, and social dysfunction. Besides, these individuals frequently report feeling ‘devalued, dismissed, and dehumanized’ when encountering health professionals who are also perpetrators of stigmatizing attitudes and discriminatory behaviors. Aims: The present study concentrates on attitudes, and behavioral responses of medical students and junior doctors toward individuals with a mental illness and explores factors associated with stigma including temperament. Methods: A cross-sectional study was conducted among medical students and junior doctors from medical schools of universities in Tunisia. All participants were invited to complete a brief anonymous electronic survey administered on the google forms online platform. Data were collected using self-administered questionnaires, Stigma Measurement, Mental Illness: Clinicians’ Attitudes (MICA), Assessment of Affective Temperament, TEMPS-A scale. Results: A total of 1,028 medical students and junior doctors were recruited. The completion of a psychiatry clerkship for medical students didn’t improve significantly the level of stigma toward people with a mental illness. Students in the fourth year had significantly the lowest MICA scores comparing to other students. Psychiatrists had significantly lower scores of explicit stigma attitudes than the other groups (Mean score = 0.42). As for other specialties, surgical residents had more stigmatizing attitudes than those who had medical specialties. 70% of participants believed that people with a mental illness are more dangerous than the other patients. Hyperthymic temperament was significantly associated with decreased stigma attitudes toward patients with mental illness. Conclusion: A combination of medical school experiences of psychiatry’s theoretical learning and clerkship and wider societal beliefs are important factors that shape students. Awareness of this will enable educators to develop locally relevant anti-stigma teaching resources throughout the psychiatry curriculum to improve students’ attitudes toward mental illnesses.
European Psychiatry, Mar 1, 2023
Introduction: Patients suffering from psychiatric illness represent a population that is particul... more Introduction: Patients suffering from psychiatric illness represent a population that is particularly vulnerable to the SARS-CoV-2 virus and to the pandemic situation due to several factors. Objectives: We aimed in our study to determine the rate of COVID-19 infection and to identify its correlated factors in outpatients of the psychiatry department of Monastir, Tunisia. Methods: This is a descriptive and analytical cross-sectional study conducted on 178 outpatients at the department of psychiatry (Monastir, Tunisia) over a period of one month (from March 2022 to April 2022). Data was collected via a questionnaire focused on two main attributes: (1) sociodemographic and clinical characteristics; (2) questions about the COVID-19 personal and family history. Results: The mean age of our population was 44.9AE13.7 years. The majority of them (81.5%) had a chronic evolution of their psychiatric disorder (> 2 years) and 68.7% were hospitalized at least once in psychiatry. Psychosis was the most represented disorder with 57.3% compared to mood disorders and anxiety disorders. Among our population, thirty seven patients (21%) had a SARS-CoV-2 infection and 3.1% required hospital care. The infection by the virus of a family member was reported by 46% of cases and 2.5% had intrafamilial death due to COVID-19 disease. Patients with depressive disorder were the most affected (55%). COVID-19 infection was significantly associated with gender (p=0.02), marital status (p=0.016), diagnosis (p=0.001), treatment (p=0.02) and intrafamilial spread of the disease (p<10-3). Conclusions: Patients with psychiatric disorders experience a distinct burden of the COVID-19 disease. Awareness of the vulnerability of this population and psychiatric institutions is necessary in order to adapt mental health care planning and implement preventive measures during potential subsequent pandemics.
BMC Psychiatry, May 6, 2020
Background: Delirium is common in critically ill patients and it is associated with poor outcomes... more Background: Delirium is common in critically ill patients and it is associated with poor outcomes. In Tunisia, however, it is still underdiagnosed as there is no validated screening tool. The aim of this study was to translate and to validate a Tunisian version of the CAM-ICU. Methods: For the validation and inter-rater reliability assessment of the Tunisian CAM-ICU, two trained intensivists independently evaluated delirium in the patients admitted to the ICU between October 2017 and June 2018. All the patients consecutively admitted to the ICU for more than 24 h and having a Richmond Agitation-Sedation Scale greater than or equal to "-3" were assessed for delirium excluding those with stroke, dementia, psychosis or persistent coma. The results were compared with the reference evaluation carried out by a psychiatrist using the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V) criteria. The inter-rater reliability was calculated using the kappa (κ) statistic. The CAM-ICU concurrent validity was assessed using Cronbach's α coefficient, sensitivity, specificity as well as positive and negative predictive values (PPV and NPV, respectively) for the two Tunisian CAM-ICU raters. Results: The study involved 137 patients [median (IQR) age: 60 [49-68] years, male sex (n = 102), invasive mechanical ventilation (n = 49)]. Using the DSM-V criteria evaluations, 46 patients were diagnosed with delirium. When applying the Tunisian version of the CAM-ICU, 38(27.7%) patients were diagnosed with delirium for the first rater and 45(32.6%) patients for the second one. The Tunisian CAM-ICU showed a very-high inter-rater reliability for both intensivists (κ = 0.844, p < 0.001). Using the DSM-V rater as the reference standard, the sensitivity of the two intensivists' evaluations was 80.4 vs. 95.7%. Specificity was 98.9% for both. The Cronbach's α of the first and second raters' evaluations using the Tunisian version of the CAM-ICU were 0.886 and 0.887, respectively.
European Psychiatry
Introductionpost-traumatic stress disorder (PTSD) is a mental health illness that can develop aft... more Introductionpost-traumatic stress disorder (PTSD) is a mental health illness that can develop after being exposed to one or more traumatic events. This is a serious, long-term emotional response to extreme psychological trauma. As for public health emergencies, it demands large-scale coordination among many staff, and participants, especially medical workers, are exposed to high levels of stress, which can easily lead to psychiatric illnesses such as social anxiety disorder (SAD). Posttraumatic stress disorder (PTSD) and social anxiety disorder (SAD) demonstrate a high degree of comorbidity, yet little is known regarding the nature of this relationship.ObjectivesThe aim of this study is to investigate the prevalence of PTSD and SAD among health workers in the emergency ward and study the relationship between PTSD and SAD and the associated factors to both disorders among health workers in the emergency ward to suggest some solutions to reduce their effects.MethodsThis is a quantitat...
European Psychiatry
IntroductionThe legally incapacitated major is any person who, having acquired the legal majority... more IntroductionThe legally incapacitated major is any person who, having acquired the legal majority, should therefore enjoy his rights, and face his social duties, but because of an alteration of his physical or mental faculties, is not able to provide alone for the safeguarding of his interests, nor to face alone his social obligations; there is, therefore, a need for protection which is the placing under guardianship.ObjectivesTo describe the clinical and sociodemographic profile of the subjects put under guardianship in the psychiatric services of Monastir.MethodsThis is a retrospective descriptive study that focused on 71 files of subjects examined in the context of psychiatric expertise of guardianship in the psychiatric department Fattouma Bourguiba of Monastir during the period from 10-02-2016 to 08-06-2022.ResultsIn total, we included 71 files of the subjects who were examined in the framework of the expert assessments of guardianship. The average age was 53 years. The predomi...
La Tunisie médicale, Sep 27, 2022
Psychology, Health & Medicine
Journal of Psychiatry, 2017
Background: There have been many studies on psychiatric disorders, but very little is known about... more Background: There have been many studies on psychiatric disorders, but very little is known about the biology of suicide with schizophrenia. In the present study, we are looking for a possible connection between paraoxonase 1 (PON1) and suicidal behavior in schizophrenic Tunisian patients. Methods: Assay of PON1 has been done for 170 schizophrenic patients with and without suicide attempts and 119 healthy controls. All patients enrolled in the study were evaluated by psychometric scales (PANSS, EGF, CGI, BPRS and CALGARY). Results:In our study, a significant decrease in the enzymatic activity of PON1 was found in schizophrenia patients compared to controls. PON1 was also significantly lower in schizophrenic patients with suicide attempt compared to those without suicide attempt. In our work, a weak correlation between the psychometric scale CGI severity of the disease, PON1 activity and suicidal act was found. Conclusions:Results of this study showed that PON 1 levels in schizophrenic patients after suicide attempt was significantly lower than in patients with suicide attempt. PON1 may be one of the biological markers of susceptibility to suicide in patients with schizophrenia.
European Neuropsychopharmacology, 2017
Frontiers in psychology, Apr 2, 2024
Journal of internal medicine. Science & art, Apr 8, 2024
Annales D Endocrinologie, Sep 1, 2020
Background: Acute myocardial infarction (AMI) is a recognized complication in patients with hyper... more Background: Acute myocardial infarction (AMI) is a recognized complication in patients with hypertrophic cardiomyopathy (HCM). However, there are limited data on outcomes of HCM patients presenting with AMI. methods: We queried the 2003-2011 Nationwide Inpatient Sample databases to identify all patients ≥18 years with the primary diagnosis of AMI. Patients with HCM were then identified using ICD-9-CM code 425.1. Logistic regression was used to compare treatment choice and outcomes in AMI patients with and without HCM. results: From 2003-2011, of 5,900,949 patients with AMI, 5,688 (0.1%) had a diagnosis of HCM. Patients with HCM were more likely to be older (71.4±13.9 years vs 67.8±14.5 years) and women (67.7% vs 40.2%). HCM patients were less likely to have traditional cardiovascular risk factors, including family history of coronary artery disease, dyslipidemia, obesity, smoking and diabetes mellitus. They were more likely to have congestive heart failure, atrial fibrillation, valvular diseases and prior history of cardiac arrest. HCM patients were less likely to have ST-elevation myocardial infarction (STEMI) (22.8% vs 37.5%, p<0.001). HCM patients with STEMI were less likely to receive thrombolysis (1.2% vs 3.8%, p<0.001) or percutaneous coronary intervention (PCI) (31.2% vs 56.8%, p<0.001). HCM patients with non-ST elevation myocardial infarction (NSTEMI) were less likely to receive PCI (14.9% vs 30.8%, p<0.001) or coronary artery bypass surgery (4.7% vs 9.6%, p<0.001). Among patients with STEMI, patients with HCM had 24% lower in-hospital mortality than patients without HCM (adjusted OR 0.76, 95 % CI 0.63-0.91, p=0.004). After further adjustment for treatment received, HCM patients with STEMI had 33% lower in-hospital mortality than patients without HCM (adjusted OR 0.67, 95% CI 0.55-0.80, p<0.001). Among patients with NSTEMI, there was no difference in in-hospital mortality in patients with and without HCM (p=0.91) (interaction p value for HCM and STEMI = 0.039). conclusion: HCM patients represent a small portion of patients with AMI and are less likely to be treated with revascularization. Compared to patients without HCM, HCM patients with STEMI have lower in-hospital mortality.
PubMed, 2014
Background: Stress is a part of the nursing profession and it is reflected in higher rates of dep... more Background: Stress is a part of the nursing profession and it is reflected in higher rates of depression and anxiety disorders. aim : This study aimed to determine the prevalence of major depression episodes (MDE), Dysthymia and generalized anxiety disorder (GAD), as well as their associated factors, in a representative sample of nurses in Sousse Farhat Hached teaching hospital, using the Tunisian version of CIDI. Methods: It's a descriptive study, carried out among a representative sample of the nursing staff of Sousse Farhat Hached teaching hospital (N=228). The data obtained was the result of an interview using the CIDI sections related to MDD, dysthymia and GAD. Sociodemographic, medical and professional data were also collected. Results: The MDE prevalence was estimated at 7.5% and was associated with the female gender, the remoteness of the workplace, the number of persons on the participant's charge, the personal antecedents of mental and organic pathologies, the job satisfaction related to internal relationships and security as well as with the wish to change position. The prevalence of Dysthymia was 5.7% and was associated with family antecedents of mental pathologies. The prevalence of TAG (4.4%) was associated with remoteness of the workplace, personal antecedents of mental pathologies and with satisfaction related to material conditions. Conclusion: The important issues of human and financial consequences of stress at work require the use of large-scale measures that should be incorporated into a strategy covering all factors and involving both health authorities and administrative occupational medicine.
European Neuropsychopharmacology, 2014
P.3.f. Psychotic disorders and treatment − Other (clinical) species (ROS) was accumulated in bloo... more P.3.f. Psychotic disorders and treatment − Other (clinical) species (ROS) was accumulated in blood. We suggest that the appearance of catalase activity in abzymes associated with compensation reduce erythrocyte catalase activity influenced by neuroleptic treatment. Conclusion: Probably, abzymes with catalase-like activity in patients with schizophrenia reduce the level of oxidative stress in blood. Obtained data will help to clarify role of IgG with catalase activities in protection against ROS in schizophrenia but this question requires further investigations. P.3.f. Psychotic disorders and treatment − Other (clinical) P.3.f.001 Impact of side effects of psychotropic drugs on the quality of life of patients with bipolar disorder
PubMed, Apr 1, 2013
Background: Major depression is a mental disorder that is associated with high morbidity and sign... more Background: Major depression is a mental disorder that is associated with high morbidity and significant mortality. It is common among primary care attenders. Few is known about major depression prevalence and associated factors, which would prevent general practitioners from diagnosing it in primary care centres and treating it adequately. Aim: To determine prevalence and correlates of major depressive episodes (MDE) in a representative sample of primary care attenders in the area of Sousse (Tunisia). Methods: A random and representative sample of primary care attenders was obtained by a two-stage sampling procedure. First, 30 primary care centres (20 urban and 10 rural) were selected, with stratification according to residency location. Second, 1246 consenting participants were systematically recruited among those centres attenders. Participants were screened, by trained interviewers, with Tunisian version of « Composite International Diagnostic Interview » CIDI.2.1. After data entry in ishell program, MDE diagnosis was obtained according to ICD-10 criteria. Results: Mean age in our sample was 43.4 ± 17.62 years, with feminine (70.9 %) and urban (67.8 %) predominance. MDE was found in 26.4 % of participants. Associated factors were female gender, marital statute of widowed or divorced and rural residency. Conclusion: This study provided data about high prevalence of MDE in the area of Sousse primary care centres and its correlated factors.
World Journal of Psychiatry
International Journal of Social Psychiatry, Feb 11, 2022
Background: Mental health-related stigma is a serious problem that has undesirable consequences f... more Background: Mental health-related stigma is a serious problem that has undesirable consequences for individuals with mental disorders including physical health disparities, increasing mortality, and social dysfunction. Besides, these individuals frequently report feeling ‘devalued, dismissed, and dehumanized’ when encountering health professionals who are also perpetrators of stigmatizing attitudes and discriminatory behaviors. Aims: The present study concentrates on attitudes, and behavioral responses of medical students and junior doctors toward individuals with a mental illness and explores factors associated with stigma including temperament. Methods: A cross-sectional study was conducted among medical students and junior doctors from medical schools of universities in Tunisia. All participants were invited to complete a brief anonymous electronic survey administered on the google forms online platform. Data were collected using self-administered questionnaires, Stigma Measurement, Mental Illness: Clinicians’ Attitudes (MICA), Assessment of Affective Temperament, TEMPS-A scale. Results: A total of 1,028 medical students and junior doctors were recruited. The completion of a psychiatry clerkship for medical students didn’t improve significantly the level of stigma toward people with a mental illness. Students in the fourth year had significantly the lowest MICA scores comparing to other students. Psychiatrists had significantly lower scores of explicit stigma attitudes than the other groups (Mean score = 0.42). As for other specialties, surgical residents had more stigmatizing attitudes than those who had medical specialties. 70% of participants believed that people with a mental illness are more dangerous than the other patients. Hyperthymic temperament was significantly associated with decreased stigma attitudes toward patients with mental illness. Conclusion: A combination of medical school experiences of psychiatry’s theoretical learning and clerkship and wider societal beliefs are important factors that shape students. Awareness of this will enable educators to develop locally relevant anti-stigma teaching resources throughout the psychiatry curriculum to improve students’ attitudes toward mental illnesses.
European Psychiatry, Mar 1, 2023
Introduction: Patients suffering from psychiatric illness represent a population that is particul... more Introduction: Patients suffering from psychiatric illness represent a population that is particularly vulnerable to the SARS-CoV-2 virus and to the pandemic situation due to several factors. Objectives: We aimed in our study to determine the rate of COVID-19 infection and to identify its correlated factors in outpatients of the psychiatry department of Monastir, Tunisia. Methods: This is a descriptive and analytical cross-sectional study conducted on 178 outpatients at the department of psychiatry (Monastir, Tunisia) over a period of one month (from March 2022 to April 2022). Data was collected via a questionnaire focused on two main attributes: (1) sociodemographic and clinical characteristics; (2) questions about the COVID-19 personal and family history. Results: The mean age of our population was 44.9AE13.7 years. The majority of them (81.5%) had a chronic evolution of their psychiatric disorder (> 2 years) and 68.7% were hospitalized at least once in psychiatry. Psychosis was the most represented disorder with 57.3% compared to mood disorders and anxiety disorders. Among our population, thirty seven patients (21%) had a SARS-CoV-2 infection and 3.1% required hospital care. The infection by the virus of a family member was reported by 46% of cases and 2.5% had intrafamilial death due to COVID-19 disease. Patients with depressive disorder were the most affected (55%). COVID-19 infection was significantly associated with gender (p=0.02), marital status (p=0.016), diagnosis (p=0.001), treatment (p=0.02) and intrafamilial spread of the disease (p<10-3). Conclusions: Patients with psychiatric disorders experience a distinct burden of the COVID-19 disease. Awareness of the vulnerability of this population and psychiatric institutions is necessary in order to adapt mental health care planning and implement preventive measures during potential subsequent pandemics.
BMC Psychiatry, May 6, 2020
Background: Delirium is common in critically ill patients and it is associated with poor outcomes... more Background: Delirium is common in critically ill patients and it is associated with poor outcomes. In Tunisia, however, it is still underdiagnosed as there is no validated screening tool. The aim of this study was to translate and to validate a Tunisian version of the CAM-ICU. Methods: For the validation and inter-rater reliability assessment of the Tunisian CAM-ICU, two trained intensivists independently evaluated delirium in the patients admitted to the ICU between October 2017 and June 2018. All the patients consecutively admitted to the ICU for more than 24 h and having a Richmond Agitation-Sedation Scale greater than or equal to "-3" were assessed for delirium excluding those with stroke, dementia, psychosis or persistent coma. The results were compared with the reference evaluation carried out by a psychiatrist using the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V) criteria. The inter-rater reliability was calculated using the kappa (κ) statistic. The CAM-ICU concurrent validity was assessed using Cronbach's α coefficient, sensitivity, specificity as well as positive and negative predictive values (PPV and NPV, respectively) for the two Tunisian CAM-ICU raters. Results: The study involved 137 patients [median (IQR) age: 60 [49-68] years, male sex (n = 102), invasive mechanical ventilation (n = 49)]. Using the DSM-V criteria evaluations, 46 patients were diagnosed with delirium. When applying the Tunisian version of the CAM-ICU, 38(27.7%) patients were diagnosed with delirium for the first rater and 45(32.6%) patients for the second one. The Tunisian CAM-ICU showed a very-high inter-rater reliability for both intensivists (κ = 0.844, p < 0.001). Using the DSM-V rater as the reference standard, the sensitivity of the two intensivists' evaluations was 80.4 vs. 95.7%. Specificity was 98.9% for both. The Cronbach's α of the first and second raters' evaluations using the Tunisian version of the CAM-ICU were 0.886 and 0.887, respectively.
European Psychiatry
Introductionpost-traumatic stress disorder (PTSD) is a mental health illness that can develop aft... more Introductionpost-traumatic stress disorder (PTSD) is a mental health illness that can develop after being exposed to one or more traumatic events. This is a serious, long-term emotional response to extreme psychological trauma. As for public health emergencies, it demands large-scale coordination among many staff, and participants, especially medical workers, are exposed to high levels of stress, which can easily lead to psychiatric illnesses such as social anxiety disorder (SAD). Posttraumatic stress disorder (PTSD) and social anxiety disorder (SAD) demonstrate a high degree of comorbidity, yet little is known regarding the nature of this relationship.ObjectivesThe aim of this study is to investigate the prevalence of PTSD and SAD among health workers in the emergency ward and study the relationship between PTSD and SAD and the associated factors to both disorders among health workers in the emergency ward to suggest some solutions to reduce their effects.MethodsThis is a quantitat...
European Psychiatry
IntroductionThe legally incapacitated major is any person who, having acquired the legal majority... more IntroductionThe legally incapacitated major is any person who, having acquired the legal majority, should therefore enjoy his rights, and face his social duties, but because of an alteration of his physical or mental faculties, is not able to provide alone for the safeguarding of his interests, nor to face alone his social obligations; there is, therefore, a need for protection which is the placing under guardianship.ObjectivesTo describe the clinical and sociodemographic profile of the subjects put under guardianship in the psychiatric services of Monastir.MethodsThis is a retrospective descriptive study that focused on 71 files of subjects examined in the context of psychiatric expertise of guardianship in the psychiatric department Fattouma Bourguiba of Monastir during the period from 10-02-2016 to 08-06-2022.ResultsIn total, we included 71 files of the subjects who were examined in the framework of the expert assessments of guardianship. The average age was 53 years. The predomi...
La Tunisie médicale, Sep 27, 2022
Psychology, Health & Medicine
Journal of Psychiatry, 2017
Background: There have been many studies on psychiatric disorders, but very little is known about... more Background: There have been many studies on psychiatric disorders, but very little is known about the biology of suicide with schizophrenia. In the present study, we are looking for a possible connection between paraoxonase 1 (PON1) and suicidal behavior in schizophrenic Tunisian patients. Methods: Assay of PON1 has been done for 170 schizophrenic patients with and without suicide attempts and 119 healthy controls. All patients enrolled in the study were evaluated by psychometric scales (PANSS, EGF, CGI, BPRS and CALGARY). Results:In our study, a significant decrease in the enzymatic activity of PON1 was found in schizophrenia patients compared to controls. PON1 was also significantly lower in schizophrenic patients with suicide attempt compared to those without suicide attempt. In our work, a weak correlation between the psychometric scale CGI severity of the disease, PON1 activity and suicidal act was found. Conclusions:Results of this study showed that PON 1 levels in schizophrenic patients after suicide attempt was significantly lower than in patients with suicide attempt. PON1 may be one of the biological markers of susceptibility to suicide in patients with schizophrenia.
European Neuropsychopharmacology, 2017