Barbara Ferriani - Academia.edu (original) (raw)

Conference Presentations by Barbara Ferriani

" Spicchi d'Igloo " , realizzata da Mario Merz nel 1985, è costituita di due elementi della stess... more " Spicchi d'Igloo " , realizzata da Mario Merz nel 1985, è costituita di due elementi della stessa dimensione: da un lato uno spicchio ricoperto da una tela dipinta e dall'altro una porzione gemella la cui struttura metallica è coperta da lastre di cera sovrapposte. Le strutture di entrambi gli spicchi sono realizzate con tubolari metallici saldati nei punti di giunzione: quella che accoglie la tela dipinta è costituita da un telaio perimetrale al quale è ancorata una rete metallica, mentre l'altra, che accoglie i pannelli di cera, è dotata di ulteriori 9 tubolari orizzontali, sui quali, in maniera volutamente imprecisa, sono fi ssate porzioni di una rada rete metallica plastifi cata verde. Sul primo spicchio l'artista ha agganciato una tela di cotone mentre nel secondo sono collocate, affastellate, 19 lastre cerose di differente forma e dimensione. Sullo spicchio dipinto le stesure pittoriche (colature simili a dripping, concrezioni di colore rappreso, energici interventi a spatola o con il retro del pennello) erano offuscate da spessi depositi atmosferici e vi erano diffuse deadesioni. Nell'altro spicchio l'impasto ceroso dei pannelli non solo era notevolmente virato di colore, ma vi erano numerose crettature, fessurazioni, distacchi e gallerie di insetti. Si rendeva necessario un intervento di restauro assai complesso in quanto non solo si doveva operare su materiali e forme di degrado assai differenti ma, considerata la natura del manufatto, bisognava preservare l'aspetto che l'opera aveva acquisito con il passare degli anni.

Papers by Barbara Ferriani

This study deals with Lucio Fontana's artworks, Concetti Spaziali, produced between 1949 and ... more This study deals with Lucio Fontana's artworks, Concetti Spaziali, produced between 1949 and 1968, and reports the results of a larger research project on his technique, carried out in collaboration with the Fondazione Fontana by international, multidisciplinary work groups in the last decade, with a special focus on a selection of artworks from the series Olii (Oils) series. It is here demonstrated, how Fontana made use of oil paints containing different lipidic binders: a non-drying oil such as castor oil, a semi-drying oil such as rapeseed oil, and the traditional siccative binder, linseed oil. It is not clear if Fontana wished to experiment with different kinds of oils in order to achieve different effects or if he simply used ready-made paints without knowing their composition. In any case, the materials and techniques he used are here proven to be closely linked to the conservation problems exhibited by the pictorial layers.

Journal of physics, Apr 1, 2022

Synthetic textiles are constituents of heritage objects and garments often displayed in museum co... more Synthetic textiles are constituents of heritage objects and garments often displayed in museum collections or preserved in archives, presenting unprecedented and specific conservation challenges. These issues need to be addressed assessing degradation processes, and developing targeted restoration and preventive conservation practices. The present work aims at characterizing the composition of high fashion garments and design textiles by Nanni Strada conserved in the archives of Nanni Strada Design Studio (Milan). To identify the chemical composition of the fibers used for the manufacturing, and to investigate the degradation processes affecting the objects, the materials were investigated by Attenuated Total Reflectance Fourier Transform Infrared Spectroscopy (ATR-FTIR), Evolved Gas Analysis coupled to Mass Spectrometry (EGA-MS), and multi-shot Pyrolysis coupled to Gas Chromatography and Mass Spectrometry (Py-GC/MS). The results will contribute to a better knowledge of the chemical properties of the textiles produced in the 1970s, and to plan conservation and exhibition strategies.

Journal of Cultural Heritage, 2019

Ochrona Dziedzictwa Kulturowego, Dec 20, 2019

Journal of Analytical and Applied Pyrolysis, Sep 1, 2018

Studies in Conservation, Jun 1, 2016

Background &amp;amp; aims: Non-alcoholic steatohepatitis (NASH) is a chronic, progressive... more Background &amp;amp; aims: Non-alcoholic steatohepatitis (NASH) is a chronic, progressive fibrotic liver disease that can lead to cirrhosis. While liver biopsy is considered the reference standard for the histologic diagnosis of NASH and staging of fibrosis, its use in clinical practice is limited. Non-invasive tests (NITs) are increasingly being used to identify and stage liver fibrosis in patients with NASH, and several can assess liver-related outcomes. We report changes in various NITs in patients treated with obeticholic acid (OCA) or placebo in the phase III REGENERATE study. Methods: Patients with NASH and fibrosis stage F2 or F3 (n = 931) were randomized (1:1:1) to receive placebo, OCA 10 mg, or OCA 25 mg once daily. Various NITs based on clinical chemistry and/or imaging were evaluated at baseline and throughout the study. Results: Rapid, sustained reductions from baseline in alanine aminotransferase (ALT), aspartate aminotransferase (AST), and gamma-glutamyltransferase levels, as well as in Fibrosis-4 (FIB-4), FibroTest, FibroMeter, and FibroScan-AST scores were observed in OCA-treated vs. placebo-treated patients. Reduction in liver stiffness by vibration-controlled transient elastography was observed in the OCA 25 mg group vs. the placebo group at Month 18. NIT changes were associated with shifts in histologic fibrosis stage. The greatest improvements were observed in patients with ≥1-stage fibrosis improvement; however, improvements in ALT, AST, FIB-4, and FibroTest were also observed in OCA-treated patients whose histologic fibrosis remained stable. Conclusions: Based on the REGENERATE Month 18 interim analysis, rapid and sustained improvements in various NITs were observed with OCA treatment. Dynamic changes in selected NITs separated histologic responders from non-responders. These results suggest that NITs may be useful in assessing histologic response to OCA therapy. CLINICALTRIALS. Gov number: NCT02548351 LAY SUMMARY: Non-alcoholic steatohepatitis (NASH) is a chronic, progressive liver disease that can lead to cirrhosis. To diagnose and assess liver fibrosis (scarring) in patients with NASH, non-invasive tests (NITs) are increasingly being used rather than liver biopsy, which is invasive, expensive, and can be risky. In the REGENERATE study, which is evaluating the effects of obeticholic acid vs. placebo in patients with NASH, various NITs were also evaluated. This analysis shows that improvements in levels of certain blood components, as well as favorable results of ultrasound imaging and proprietary tests of liver function, were associated with improvements in liver fibrosis after treatment with obeticholic acid, suggesting that NITs may be useful alternatives to liver biopsy in assessing NASH patients&amp;#39; response to therapy.

Journal of Physics: Conference Series

Mousse Publishing, 2018

Background & aims: Non-alcoholic steatohepatitis (NASH) is a chronic, progressive fibroti... more Background & aims: Non-alcoholic steatohepatitis (NASH) is a chronic, progressive fibrotic liver disease that can lead to cirrhosis. While liver biopsy is considered the reference standard for the histologic diagnosis of NASH and staging of fibrosis, its use in clinical practice is limited. Non-invasive tests (NITs) are increasingly being used to identify and stage liver fibrosis in patients with NASH, and several can assess liver-related outcomes. We report changes in various NITs in patients treated with obeticholic acid (OCA) or placebo in the phase III REGENERATE study. Methods: Patients with NASH and fibrosis stage F2 or F3 (n = 931) were randomized (1:1:1) to receive placebo, OCA 10 mg, or OCA 25 mg once daily. Various NITs based on clinical chemistry and/or imaging were evaluated at baseline and throughout the study. Results: Rapid, sustained reductions from baseline in alanine aminotransferase (ALT), aspartate aminotransferase (AST), and gamma-glutamyltransferase levels, as well as in Fibrosis-4 (FIB-4), FibroTest, FibroMeter, and FibroScan-AST scores were observed in OCA-treated vs. placebo-treated patients. Reduction in liver stiffness by vibration-controlled transient elastography was observed in the OCA 25 mg group vs. the placebo group at Month 18. NIT changes were associated with shifts in histologic fibrosis stage. The greatest improvements were observed in patients with ≥1-stage fibrosis improvement; however, improvements in ALT, AST, FIB-4, and FibroTest were also observed in OCA-treated patients whose histologic fibrosis remained stable. Conclusions: Based on the REGENERATE Month 18 interim analysis, rapid and sustained improvements in various NITs were observed with OCA treatment. Dynamic changes in selected NITs separated histologic responders from non-responders. These results suggest that NITs may be useful in assessing histologic response to OCA therapy. CLINICALTRIALS. Gov number: NCT02548351 LAY SUMMARY: Non-alcoholic steatohepatitis (NASH) is a chronic, progressive liver disease that can lead to cirrhosis. To diagnose and assess liver fibrosis (scarring) in patients with NASH, non-invasive tests (NITs) are increasingly being used rather than liver biopsy, which is invasive, expensive, and can be risky. In the REGENERATE study, which is evaluating the effects of obeticholic acid vs. placebo in patients with NASH, various NITs were also evaluated. This analysis shows that improvements in levels of certain blood components, as well as favorable results of ultrasound imaging and proprietary tests of liver function, were associated with improvements in liver fibrosis after treatment with obeticholic acid, suggesting that NITs may be useful alternatives to liver biopsy in assessing NASH patients' response to therapy.