BILAL HUSSAIN - Academia.edu (original) (raw)

Papers by BILAL HUSSAIN

Research paper thumbnail of اعداد اختبار بول نيوتن للقدرة على الاستدلال العددي وفقاً لنظرية السمات الكامنة بأستخدام انموذج راش

Research paper thumbnail of A rare cardiac manifestation of Brucellosis (RCD code: VIII)

Journal of Rare Cardiovascular Diseases, 2017

Brucellosis, a zoonosis caused by gram negative bacillus Brucella, is characterized by a systemic... more Brucellosis, a zoonosis caused by gram negative bacillus Brucella, is characterized by a systemic illness with vague symptoms. Though, cardiac involvement with Brucella is reported mostly as endocarditis, the occurrence of exclusive Brucella constrictive pericarditis without endocardium involvement is extremely rare. We report a case of a young villager who presented with symptoms of low grade fever, dypnea and malaise with signs of right heart failure. He was diagnosed to have constrictive pericarditis on 2-D echocardiogram and the diagnosis was confirmed by cardiac magnetic resonance(CMR) imaging. A pericardiectomy was performed for the relief of pericardial constriction. The patient, however, continued to have low grade fever and lethargy. A workup for chronic infections revealed strongly positive titres for Brucella, indicating that the patient was suffering from systemic Brucellosis. The patient was treated with combination of antibiotics for six weeks and responded well to tre...

Research paper thumbnail of Caught in the act - Migration of a large right atrial thrombus to pulmonary artery during transthoracic echocardiography - A case report

JPMA. The Journal of the Pakistan Medical Association, 2017

In cases of pulmonary embolism, the visualization of a free-floating right heart thrombus on conv... more In cases of pulmonary embolism, the visualization of a free-floating right heart thrombus on conventional transthoracic echocardiography is extremely rare. Even rarer is an echocardiographic recording of migration of a free-floating clot from the right heart into the pulmonary vasculature leading to pulmonary embolism. We present a unique case of an elderly man who presented with dyspnoea, in whom a routine 2-D bed side transthoracic echo recorded the live transit of a free floating thrombus from the right heart into the pulmonary artery resulting in pulmonary embolism. The patient remained haemodynamically stable and was managed with anticoagulation. Our case objectively highlights the rare occurrence of free floating right heart thrombi and their association with pulmonary embolism and also focuses on the options of management of such thrombi.

Research paper thumbnail of Wide Scanning Angle Millimetre Wave 1 × 4 Planar Antenna Array on InP at 300 GHz

Applied Sciences, 2021

The design of a uniformly spaced 1 × 4 linear antenna array using epitaxial layers of benzocyclob... more The design of a uniformly spaced 1 × 4 linear antenna array using epitaxial layers of benzocyclobutene over an InP substrate is demonstrated. The array elements are conjugately matched with a uni-travelling carrier photodiode at the input. The phased array is optimised to counteract mutual coupling effects by introducing metal strips with isolated ground planes for each radiating element. The proposed antenna array can provide a gain of 10 dBi with a gain variation of ±3 dB. The array operates over a bandwidth of 10 GHz (295–305 GHz) with a wide scanning angle of 100° in the broadside.

Research paper thumbnail of Cardiac magnetic resonance imaging in a young patient with left ventricular spongiform cardiomyopathy: A case report and review of literature

JPMA. The Journal of the Pakistan Medical Association, 2018

Left ventricular spongiform or non compaction cardiomyopathy is one of the rarer forms of cardiom... more Left ventricular spongiform or non compaction cardiomyopathy is one of the rarer forms of cardiomyopathy with a reported prevalence of 0.014-0.05% in adults. It is characterized by severe left ventricular systolic dysfunction occurring secondary to the failure of the myocardium to fuse resulting in non-compacted myocardium with a trabeculated appearance of the myocardium. Initially described on the basis of 2-D echocardiography, the identification of left ventricular non compaction has now improved with the introduction of sophisticated imaging modalities such as cardiac magnetic resonance imaging that allows better visualization of the non-compacted myocardium assisting in accurate diagnosis. We report a case of isolated left ventricular spongiform or non-compaction cardiomyopathy that was diagnosed on cardiac magnetic resonance imaging with classical features. The patient was started on standard heart failure medications along with anticoagulation and continues to do well on follo...

Research paper thumbnail of Design of Passive Components for Microwave Photonics-based Millimetre Wave Systems

Next Generation Wireless Terahertz Communication Networks, 2021

Research paper thumbnail of High-Performance Beamforming Network Based on Si-Photonics Phase Shifters for Wideband Communications and Radar Applications

IEEE Journal of Selected Topics in Quantum Electronics, 2020

The evolution of microwave and mm-wave systems for communication and remote sensing is heading to... more The evolution of microwave and mm-wave systems for communication and remote sensing is heading towards a massive deployment of phased-array antennas with beamforming capabilities. 5G wireless access networks are expected to employ beamforming to optimize resources allocation, whereas radars will benefit from precise and fast-scanning antennas. Moreover, in the next future, those systems are expected to widely employ photonic technologies for signal generation, acquisition, and distribution. In this scenario, photonics can allow for the development of high-performance beamforming networks, which can easily be integrated in photonics-assisted RF systems, combining broad operational bandwidth, low signal distortion, and high pointing precision with unprecedented flexibility. In this paper, a phase shift-based beamforming network for microwave applications is presented and its performance analyzed. The Si-photonics integrated phase shifters exhibit large phase shift (>360°) and limited amplitude fluctuations (∼2.5 dB). The packaged beamforming network elements show extremely low signal distortion, low steering error (<3°), and fast switching time (<5 ns), demonstrated by the transmission with beam-steering of a 2-Gb/s communication signal and of a 1-GHz chirped radar waveform. A comparison with commercial RF devices shows that the photonics-assisted beamforming network is well-suited for high bit-rate 5G communications and for wideband radar applications.

Research paper thumbnail of Thermal vulnerability detection in integrated electronic and photonic circuits using infrared thermography

Applied Optics, 2020

Failure prediction of any electrical/optical component is crucial for estimating its operating li... more Failure prediction of any electrical/optical component is crucial for estimating its operating life. Using high temperature operating life (HTOL) tests, it is possible to model the failure mechanisms for integrated circuits. Conventional HTOL standards are not suitable for operating life prediction of photonic components owing to their functional dependence on the thermo-optic effect. This work presents an infrared (IR)-assisted thermal vulnerability detection technique suitable for photonic as well as electronic components. By accurately mapping the thermal profile of an integrated circuit under a stress condition, it is possible to precisely locate the heat center for predicting the long-term operational failures within the device under test. For the first time, the reliability testing is extended to a fully functional microwave photonic system using conventional IR thermography. By applying image fusion using affine transformation on multimodal acquisition, it was demonstrated th...

Research paper thumbnail of Right atrial myxoma in a patient with Budd-Chiari syndrome (RCD code: VI-1A.1)

Journal of Rare Cardiovascular Diseases, 2018

Budd-Chiari syndrome (BCS) is a rare clinical disorder which is caused by obstruction of the majo... more Budd-Chiari syndrome (BCS) is a rare clinical disorder which is caused by obstruction of the major hepatic veins or suprahepatic portion of the inferior vena cava. Either thrombosis or a mechanical venous obstruction may be present. BCS has been shown to be associated with a number of diseases including polycythaemia vera, myeloproliferative disorders, malignancy or congenital web of the gastro-intestinal tract. Right-sided cardiac tumours, although rarely reported as a cause for BCS, are generally considered as a surgically curable cause for this otherwise potentially lethal clinical condition.

Research paper thumbnail of Treatment of a Rare Vascular Complication of Coronary Stenting in an Octagenarian

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2018

The ability of drug-eluting stent (DES) to inhibit intimal proliferation has resulted in a massiv... more The ability of drug-eluting stent (DES) to inhibit intimal proliferation has resulted in a massive increase in their usage over the years. However, it is known that the application of DES can alter the normal cascade of vascular healing, resulting in delayed endothelialisation with risk of vascular complications. Coronary artery aneurysms (CAN) are defined as more than 50% dilatation of the coronary artery compared to the reference vessel diameter with the reported incidence after percutaneous intervention (PCI) being only around 0.35 to 6.0%. Previously, CAN had been reported with the use of bare metal stent secondary to stretch, stent fracture and dissection. However, recently, increasing number of cases have been reported describing CAN after DES implantation. To the best of the authors' knowledge, they present the first case from Pakistan of a left anterior descending coronary artery aneurysm after DES implantation treated successfully with stenting under intravascular ultra...

Research paper thumbnail of Positive Teacher-Student Relationship and Teachers Experience-A Teacher’s Perspective

Global Journal of Management and Business Research, Sep 4, 2013

This is a descriptive study of a teacher's perspective regarding creating and maintaining a posit... more This is a descriptive study of a teacher's perspective regarding creating and maintaining a positive teacher-student relationship with the teacher's professional experience at undergraduate levels. The study is a qualitative study involving interviews with a convenience sample selected randomly. The study was carried out with a sample size of 60 teachers from universities located in Islamabad/ Rawalpindi Pakistan. Teachers emphasized the importance of positive teacher-student relationship and concluded that such relationship increases the confidence level of the students, produces mutual respect and obedience. Findings of the interview results indicated that building a positive teacher-student relationship is a time taking process; that comes with teacher's experience and it varies with the passage of time.

Research paper thumbnail of Discriminating instance generation for automated constraint model selection

One approach to automated constraint modelling is to generate, and then select from, a set of can... more One approach to automated constraint modelling is to generate, and then select from, a set of candidate models. This method is used by the automated modelling system CONJURE. To select a preferred model or set of models for a problem class from the candidates CONJURE produces, we use a set of training instances drawn from the target class. It is important that the training instances are discriminating. If all models solve a given instance in a trivial amount of time, or if no models solve it in the time available, then the instance is not useful for model selection. This paper addresses the task of generating small sets of discriminating training instances automatically. The instance space is determined by the parameters of the associated problem class. We develop a number of methods of finding parameter configurations that give discriminating training instances, some of them leveraging existing parameter-tuning techniques. Our experimental results confirm the success of our approach in reducing a large set of input models to a small set that we can expect to perform well for the given problem class.

Research paper thumbnail of Rosmarinus officinalis essential oil: antiproliferative, antioxidant and antibacterial activities

Brazilian Journal of Microbiology, 2010

The aim of this work was to investigate and compare the antiproliferative, antioxidant and antiba... more The aim of this work was to investigate and compare the antiproliferative, antioxidant and antibacterial activities of Rosmarinus officinalis essential oil, native to Pakistan. The essential oil content from the leaves of R. officinalis was 0.93 g 100g-1. The GC and GC-MS analysis revealed that the major components determined in R. officinalis essential oil were 1,8-cineol (38.5%), camphor (17.1%),-pinene (12.3%), limonene (6.23%), camphene (6.00%) and linalool (5.70%). The antiproliferative activity was tested against two cancer (MCF-7 and LNCaP) and one fibroblast cell line (NIH-3T3) using the MTT assay, while, the antioxidant activity was evaluated by the reduction of 2, 2-diphenyl-1-picryl hydrazyl (DPPH) and measuring percent inhibition of peroxidation in linoleic acid system. The disc diffusion and modified resazurin microtitre-plate assays were used to evaluate the inhibition zones (IZ) and minimum inhibitory concentration (MIC) of R. officinalis essential oil, respectively. It is concluded from the results that Rosmarinus officinalis essential oil exhibited antiproliferative, antioxidant and antibacterial activities.

Research paper thumbnail of Small and medium enterprises in Pakistan

South Asian Journal, 2005

Research paper thumbnail of اعداد اختبار بول نيوتن للقدرة على الاستدلال العددي وفقاً لنظرية السمات الكامنة بأستخدام انموذج راش

Research paper thumbnail of A rare cardiac manifestation of Brucellosis (RCD code: VIII)

Journal of Rare Cardiovascular Diseases, 2017

Brucellosis, a zoonosis caused by gram negative bacillus Brucella, is characterized by a systemic... more Brucellosis, a zoonosis caused by gram negative bacillus Brucella, is characterized by a systemic illness with vague symptoms. Though, cardiac involvement with Brucella is reported mostly as endocarditis, the occurrence of exclusive Brucella constrictive pericarditis without endocardium involvement is extremely rare. We report a case of a young villager who presented with symptoms of low grade fever, dypnea and malaise with signs of right heart failure. He was diagnosed to have constrictive pericarditis on 2-D echocardiogram and the diagnosis was confirmed by cardiac magnetic resonance(CMR) imaging. A pericardiectomy was performed for the relief of pericardial constriction. The patient, however, continued to have low grade fever and lethargy. A workup for chronic infections revealed strongly positive titres for Brucella, indicating that the patient was suffering from systemic Brucellosis. The patient was treated with combination of antibiotics for six weeks and responded well to tre...

Research paper thumbnail of Caught in the act - Migration of a large right atrial thrombus to pulmonary artery during transthoracic echocardiography - A case report

JPMA. The Journal of the Pakistan Medical Association, 2017

In cases of pulmonary embolism, the visualization of a free-floating right heart thrombus on conv... more In cases of pulmonary embolism, the visualization of a free-floating right heart thrombus on conventional transthoracic echocardiography is extremely rare. Even rarer is an echocardiographic recording of migration of a free-floating clot from the right heart into the pulmonary vasculature leading to pulmonary embolism. We present a unique case of an elderly man who presented with dyspnoea, in whom a routine 2-D bed side transthoracic echo recorded the live transit of a free floating thrombus from the right heart into the pulmonary artery resulting in pulmonary embolism. The patient remained haemodynamically stable and was managed with anticoagulation. Our case objectively highlights the rare occurrence of free floating right heart thrombi and their association with pulmonary embolism and also focuses on the options of management of such thrombi.

Research paper thumbnail of Wide Scanning Angle Millimetre Wave 1 × 4 Planar Antenna Array on InP at 300 GHz

Applied Sciences, 2021

The design of a uniformly spaced 1 × 4 linear antenna array using epitaxial layers of benzocyclob... more The design of a uniformly spaced 1 × 4 linear antenna array using epitaxial layers of benzocyclobutene over an InP substrate is demonstrated. The array elements are conjugately matched with a uni-travelling carrier photodiode at the input. The phased array is optimised to counteract mutual coupling effects by introducing metal strips with isolated ground planes for each radiating element. The proposed antenna array can provide a gain of 10 dBi with a gain variation of ±3 dB. The array operates over a bandwidth of 10 GHz (295–305 GHz) with a wide scanning angle of 100° in the broadside.

Research paper thumbnail of Cardiac magnetic resonance imaging in a young patient with left ventricular spongiform cardiomyopathy: A case report and review of literature

JPMA. The Journal of the Pakistan Medical Association, 2018

Left ventricular spongiform or non compaction cardiomyopathy is one of the rarer forms of cardiom... more Left ventricular spongiform or non compaction cardiomyopathy is one of the rarer forms of cardiomyopathy with a reported prevalence of 0.014-0.05% in adults. It is characterized by severe left ventricular systolic dysfunction occurring secondary to the failure of the myocardium to fuse resulting in non-compacted myocardium with a trabeculated appearance of the myocardium. Initially described on the basis of 2-D echocardiography, the identification of left ventricular non compaction has now improved with the introduction of sophisticated imaging modalities such as cardiac magnetic resonance imaging that allows better visualization of the non-compacted myocardium assisting in accurate diagnosis. We report a case of isolated left ventricular spongiform or non-compaction cardiomyopathy that was diagnosed on cardiac magnetic resonance imaging with classical features. The patient was started on standard heart failure medications along with anticoagulation and continues to do well on follo...

Research paper thumbnail of Design of Passive Components for Microwave Photonics-based Millimetre Wave Systems

Next Generation Wireless Terahertz Communication Networks, 2021

Research paper thumbnail of High-Performance Beamforming Network Based on Si-Photonics Phase Shifters for Wideband Communications and Radar Applications

IEEE Journal of Selected Topics in Quantum Electronics, 2020

The evolution of microwave and mm-wave systems for communication and remote sensing is heading to... more The evolution of microwave and mm-wave systems for communication and remote sensing is heading towards a massive deployment of phased-array antennas with beamforming capabilities. 5G wireless access networks are expected to employ beamforming to optimize resources allocation, whereas radars will benefit from precise and fast-scanning antennas. Moreover, in the next future, those systems are expected to widely employ photonic technologies for signal generation, acquisition, and distribution. In this scenario, photonics can allow for the development of high-performance beamforming networks, which can easily be integrated in photonics-assisted RF systems, combining broad operational bandwidth, low signal distortion, and high pointing precision with unprecedented flexibility. In this paper, a phase shift-based beamforming network for microwave applications is presented and its performance analyzed. The Si-photonics integrated phase shifters exhibit large phase shift (>360°) and limited amplitude fluctuations (∼2.5 dB). The packaged beamforming network elements show extremely low signal distortion, low steering error (<3°), and fast switching time (<5 ns), demonstrated by the transmission with beam-steering of a 2-Gb/s communication signal and of a 1-GHz chirped radar waveform. A comparison with commercial RF devices shows that the photonics-assisted beamforming network is well-suited for high bit-rate 5G communications and for wideband radar applications.

Research paper thumbnail of Thermal vulnerability detection in integrated electronic and photonic circuits using infrared thermography

Applied Optics, 2020

Failure prediction of any electrical/optical component is crucial for estimating its operating li... more Failure prediction of any electrical/optical component is crucial for estimating its operating life. Using high temperature operating life (HTOL) tests, it is possible to model the failure mechanisms for integrated circuits. Conventional HTOL standards are not suitable for operating life prediction of photonic components owing to their functional dependence on the thermo-optic effect. This work presents an infrared (IR)-assisted thermal vulnerability detection technique suitable for photonic as well as electronic components. By accurately mapping the thermal profile of an integrated circuit under a stress condition, it is possible to precisely locate the heat center for predicting the long-term operational failures within the device under test. For the first time, the reliability testing is extended to a fully functional microwave photonic system using conventional IR thermography. By applying image fusion using affine transformation on multimodal acquisition, it was demonstrated th...

Research paper thumbnail of Right atrial myxoma in a patient with Budd-Chiari syndrome (RCD code: VI-1A.1)

Journal of Rare Cardiovascular Diseases, 2018

Budd-Chiari syndrome (BCS) is a rare clinical disorder which is caused by obstruction of the majo... more Budd-Chiari syndrome (BCS) is a rare clinical disorder which is caused by obstruction of the major hepatic veins or suprahepatic portion of the inferior vena cava. Either thrombosis or a mechanical venous obstruction may be present. BCS has been shown to be associated with a number of diseases including polycythaemia vera, myeloproliferative disorders, malignancy or congenital web of the gastro-intestinal tract. Right-sided cardiac tumours, although rarely reported as a cause for BCS, are generally considered as a surgically curable cause for this otherwise potentially lethal clinical condition.

Research paper thumbnail of Treatment of a Rare Vascular Complication of Coronary Stenting in an Octagenarian

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2018

The ability of drug-eluting stent (DES) to inhibit intimal proliferation has resulted in a massiv... more The ability of drug-eluting stent (DES) to inhibit intimal proliferation has resulted in a massive increase in their usage over the years. However, it is known that the application of DES can alter the normal cascade of vascular healing, resulting in delayed endothelialisation with risk of vascular complications. Coronary artery aneurysms (CAN) are defined as more than 50% dilatation of the coronary artery compared to the reference vessel diameter with the reported incidence after percutaneous intervention (PCI) being only around 0.35 to 6.0%. Previously, CAN had been reported with the use of bare metal stent secondary to stretch, stent fracture and dissection. However, recently, increasing number of cases have been reported describing CAN after DES implantation. To the best of the authors' knowledge, they present the first case from Pakistan of a left anterior descending coronary artery aneurysm after DES implantation treated successfully with stenting under intravascular ultra...

Research paper thumbnail of Positive Teacher-Student Relationship and Teachers Experience-A Teacher’s Perspective

Global Journal of Management and Business Research, Sep 4, 2013

This is a descriptive study of a teacher's perspective regarding creating and maintaining a posit... more This is a descriptive study of a teacher's perspective regarding creating and maintaining a positive teacher-student relationship with the teacher's professional experience at undergraduate levels. The study is a qualitative study involving interviews with a convenience sample selected randomly. The study was carried out with a sample size of 60 teachers from universities located in Islamabad/ Rawalpindi Pakistan. Teachers emphasized the importance of positive teacher-student relationship and concluded that such relationship increases the confidence level of the students, produces mutual respect and obedience. Findings of the interview results indicated that building a positive teacher-student relationship is a time taking process; that comes with teacher's experience and it varies with the passage of time.

Research paper thumbnail of Discriminating instance generation for automated constraint model selection

One approach to automated constraint modelling is to generate, and then select from, a set of can... more One approach to automated constraint modelling is to generate, and then select from, a set of candidate models. This method is used by the automated modelling system CONJURE. To select a preferred model or set of models for a problem class from the candidates CONJURE produces, we use a set of training instances drawn from the target class. It is important that the training instances are discriminating. If all models solve a given instance in a trivial amount of time, or if no models solve it in the time available, then the instance is not useful for model selection. This paper addresses the task of generating small sets of discriminating training instances automatically. The instance space is determined by the parameters of the associated problem class. We develop a number of methods of finding parameter configurations that give discriminating training instances, some of them leveraging existing parameter-tuning techniques. Our experimental results confirm the success of our approach in reducing a large set of input models to a small set that we can expect to perform well for the given problem class.

Research paper thumbnail of Rosmarinus officinalis essential oil: antiproliferative, antioxidant and antibacterial activities

Brazilian Journal of Microbiology, 2010

The aim of this work was to investigate and compare the antiproliferative, antioxidant and antiba... more The aim of this work was to investigate and compare the antiproliferative, antioxidant and antibacterial activities of Rosmarinus officinalis essential oil, native to Pakistan. The essential oil content from the leaves of R. officinalis was 0.93 g 100g-1. The GC and GC-MS analysis revealed that the major components determined in R. officinalis essential oil were 1,8-cineol (38.5%), camphor (17.1%),-pinene (12.3%), limonene (6.23%), camphene (6.00%) and linalool (5.70%). The antiproliferative activity was tested against two cancer (MCF-7 and LNCaP) and one fibroblast cell line (NIH-3T3) using the MTT assay, while, the antioxidant activity was evaluated by the reduction of 2, 2-diphenyl-1-picryl hydrazyl (DPPH) and measuring percent inhibition of peroxidation in linoleic acid system. The disc diffusion and modified resazurin microtitre-plate assays were used to evaluate the inhibition zones (IZ) and minimum inhibitory concentration (MIC) of R. officinalis essential oil, respectively. It is concluded from the results that Rosmarinus officinalis essential oil exhibited antiproliferative, antioxidant and antibacterial activities.

Research paper thumbnail of Small and medium enterprises in Pakistan

South Asian Journal, 2005