Uros Babic - Academia.edu (original) (raw)

Papers by Uros Babic

Research paper thumbnail of Massive retroperitoneal hematoma as a complication of anticoagulation therapy in a patient treated in a pulmonary intensive care unit

Vojnosanitetski pregled, 2015

Retroperitoneal hematoma may occur as a result of trauma, but also from rapture of arterial aneur... more Retroperitoneal hematoma may occur as a result of trauma, but also from rapture of arterial aneurysms (aortic or iliac), surgical complications, tumors or anticoagulation therapy. We presented a patient on permanent anticoagulation therapy. On the day of admission to our institudon, the patient had the value of his INR 5.57 which required immediate suspension of the therapy. The main symptom in this patient was pain in the right inguinal canal with propagation along the right leg, which was indicated in clinical picture of spontaneous retroperitoneal haematoma. After three days the fall of hemoglobin occurred, so the additonal diagnostics was done. A computed tomography of the abdomen was performed showing well limited, large retroperitoneal hematoma (213 x 79 x 91 mm). Transfusion of concentrated red blood cells was performed twice with satisfactory correction of hemoglobin level, and four units of fresh frozen plasma. The patient was hemodynamically stabilized and discharged after a two-month long intensive care unit treatment, with the advice to use low-molecular weight heparin 2 x 0.4 mg subcutaneusly, due to persistent arrhythmia. In patients on anticoagulation therapy regular monitoring of the anticoagulant status is extremely important, because of the possibility of fatal complications development, such as retroperitoneal hematoma.

Research paper thumbnail of Retrospective evaluation of male slings for patients with urinary incontinence after radical prostatectomy - one surgeon’s experience

Acta chirurgica iugoslavica, 2014

Stress urinary incontinence is one of the main complications after radical prostatectomy (RP) wit... more Stress urinary incontinence is one of the main complications after radical prostatectomy (RP) with a significant percentage of patients reporting bothersome incontinence > 1 year after surgery. Assessment of one surgeon's results in surgical treatment of urinary stress incontinence of patients with radical prostatectomy applying transobturator and suprapubic slings. From February 2010-February 2014, 20 patients, age 57-76, with moderate and severe stress urinary incontinence (SUI) were treated surgically. All patients previously had radical prostatectomy due to prostate cancer. All 20 patients with stress urinary incontinence (PRPUI) had Argus slings placement after radical prostatectomy. Patients were followed for a longer period of time, 6 months minimum, 48 months maximum.18 patients (90%) had negative, dry PAD test after surgery, one patient (5%) had positive PAD test, and one patient (5%) who previously had Advance transobturator sling placement with no positive results, had sling removed due to an infection. 6 patients (30%) needed additional sling adjustment, performed between 9-21st day after the surgery. We concluded that Argus sligs, suprapubic or transobturatory are an effective and safe treatment for PRPUI. This procedure is minimal invasive and our results clearly demonstrate that both heavy and moderate incontinence responds well.

Research paper thumbnail of Diode laser vaporization of prostate as treatment for benign prostatic enlargement: Initial results of 73 patients with 1 year follow-up

Acta chirurgica iugoslavica, 2014

Objec tive: Our ob jec tive is to eval u ate the ef ficacy, safety and 12 month out come of a 980... more Objec tive: Our ob jec tive is to eval u ate the ef ficacy, safety and 12 month out come of a 980 nm di ode la ser with Twister fi ber in the treat ment of be nign pros tatic en large ment.

Research paper thumbnail of Surgical care vesicovaginal fistulas in women with malignant gynecological disease

Acta chirurgica iugoslavica, 2014

Vesicovaginal fistulae (VVF)rep re sents one of the most fre quent com pli ca tions of var i ous ... more Vesicovaginal fistulae (VVF)rep re sents one of the most fre quent com pli ca tions of var i ous gynecolog i cal and ob stet ric pro ce dures. In pres ence of a gynecological ma lig nant tu mor, fis tula could be the out come of sur gi cal com pli ca tions, ra dio therapy or con se quence of the tu mor pro cess. Rep a ration of these fistulae is a very com plex prob lem. Our aim was to an a lyze the re sults of sur gi cal care VVF-s oc curred in women with ma lig nant gynecological dis ease which was treated sur gi cally or with radiotherapy. Out of the 48 sur gi cally treated patients with pri mary VVF, in 28 of them fis tula oc curred after hys ter ec tomy, and in 20 pa tients af ter ra dio therapy. In 15 pa tients (31.25%) transvaginal ap proach was ap plied, and in 33 pa tients (68.75%) abdominal ap proach was ap plied, with the in ter po si tion of a well vascularized lobe be ing used in 25 pa tients. All the VVFs that oc curred af ter ra dio ther apy were re paired by us ing the ab dom i nal ap proach. The ef fi ciency of sur gi cal treat ment of VVFs af ter hys ter ec tomy due to a ma lig nant dis ease was 78.5%, and af ter ra dio therapy 65%. In pa tients that have not been sub jected to ra dio ther apy, de pend ing on the char ac ter is tics of the fis tula, transvaginal or ab dom i nal ap proach is ap plica ble in VVF rep a ra tion, while the ab dom i nal approach re mains a golden stan dard in post-ra di a tion fis tula treat ment, de spite the fact that it has not solved the prob lem af ter the first med i cal treat ment in as far as 35% of pa tients.

Research paper thumbnail of Cross-Cultural Adaptation and Validation of the Serbian Version of the ICS SF Male Questionnaire

The Scientific World Journal, 2015

Introduction. The objective of this study was to cross-culturally adapt and validate ICS male SF ... more Introduction. The objective of this study was to cross-culturally adapt and validate ICS male SF questionnaire to Serbian language. Materials and Methods. This study included 91 male patients with lower urinary tract symptoms and 24 men with similar age and with confirmed absence of LUTS. ICS male SF questionnaire was translated from English to Serbian language and then back-translated to English. Results. Internal consistency was high in both dimensions, voiding (Cronbach's alpha = 0.916) and incontinence (Cronbach's alpha = 0.763). Comparison of the average scores between patients and controls revealed significant differences in both dimensions: voiding (med = 8 versus med = 0; < 0.001) and incontinence (med = 3 versus med = 0; < 0.001). Interclass correlation revealed high testretest validity in both dimensions, voiding ICC = 0.992 ( < 0.001) and incontinece ICC = 0.989 ( < 0.001). Correlation analysis revealed high agreement between ICS male SF voiding dimension and IPSS questionnaire ( = 0.943; < 0.001). Conclusion. The Serbian version of male ICS SF questionnaire showed acceptable reliability and validity. The ICS male SF questionnaire could be used in routine practice as an easy and comprehensive tool for assessment of LUTS.

Research paper thumbnail of Evaluation of compliance to local guidelines for risk factor based screening for gestational diabetes mellitus in Trebinje and Belgrade

Research paper thumbnail of Relationship between mid-trimester ultrasound fetal liver length measurements and gestational diabetes mellitus

Journal of Diabetes, 2014

The aim of the present study was to investigate the relationship between mid-trimester ultrasound... more The aim of the present study was to investigate the relationship between mid-trimester ultrasound fetal liver length (FLL) and gestational diabetes mellitus (GDM) in a high-risk population. A prospective study was performed in 331 women with singleton pregnancies who were at high risk of GDM and were undergoing a mid-trimester ultrasound examination. The ultrasound scan at 23 weeks gestation was followed by a 100-g oral glucose tolerance test (OGTT) at 24 weeks gestation. Correlations between FLL and OGTT results at different time points were tested. Receiver operating characteristic (ROC) analysis of FLL as a potential prognostic factor for GDM was also performed. In GDM patients, there was a significant positive correlation (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01) between FLL and OGTT glycemia immediately before and 60, 120, and 180 min after glucose intake. Mean FLL in GDM was significantly higher than in healthy subjects (41.04 vs 31.09 mm, respectively; P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.001). When tested as a potential prognostic factor for GDM, fetal liver measurements showed excellent diagnostic performance. The ROC analysis established a cut-off value of FLL of 39 mm for the prediction GDM, with sensitivity of 71.76%, specificity 97.56%, positive predictive value 91.0%, and negative predictive value 90.9%. The usefulness of FLL measurements was supported by a high area under the ROC curve (90.5%). In conclusion, there is a strong correlation between FLL and OGTT results, with FLL possibly serving as a valid marker for the prediction of GDM in high-risk populations.

Research paper thumbnail of Management of penile trauma caused by a dog bite

Acta chirurgica iugoslavica, 2014

Dog bites to the external genitalia are extremely rare. The literature shows only sporadic cases ... more Dog bites to the external genitalia are extremely rare. The literature shows only sporadic cases of penile injuries due to dog bites, presenting mostly as children and adolescents. We report the case of a 45-year old patient with avulsion and traumatic de-gloving of the penile skin, with exposure of the tunica albuginea, which surrounds the cavernous bodies. Dog bite wounds pose a serious medical threat. An effective initial treatment of the wound, as well as adequate supportive treatments are essential for the efficient healing of the resulting infection.

Research paper thumbnail of Pre and post test HAMA scores in women undergoing oral glucose challenge test

Research paper thumbnail of Comparative analysis of current payment system for hospital services in Serbia and projected payments under diagnostic related groups system in urology

Vojnosanitetski pregled, 2014

Background/Aim. Global budget per calendar year is a traditional method of funding hospitals in S... more Background/Aim. Global budget per calendar year is a traditional method of funding hospitals in Serbia. Diagnose related groups (DGR) is a method of hospital payment based on classification of patients into groups with clinically similar problems and similar utilization of hospital resources. The aim of this study was to compare current methods of hospital services payment with the projected costs by DRG payment method in urology. Methods. The data were obtained from the information system used in the Clinical Hospital Center "Dr. Dragiša Mišović" -Dedinje in Belgrade, Serbia. The implemented hospital information system was the main criterion for selection of healthcare institutions. The study included 994 randomly selected patients treated surgically and conservatively in 2012. Results.

Research paper thumbnail of A novel technique for treatment of mitral valve prolapse/flail

Journal of Thoracic and Cardiovascular Surgery, 2009

Research paper thumbnail of Massive retroperitoneal hematoma as a complication of anticoagulation therapy in a patient treated in a pulmonary intensive care unit

Vojnosanitetski pregled, 2015

Retroperitoneal hematoma may occur as a result of trauma, but also from rapture of arterial aneur... more Retroperitoneal hematoma may occur as a result of trauma, but also from rapture of arterial aneurysms (aortic or iliac), surgical complications, tumors or anticoagulation therapy. We presented a patient on permanent anticoagulation therapy. On the day of admission to our institudon, the patient had the value of his INR 5.57 which required immediate suspension of the therapy. The main symptom in this patient was pain in the right inguinal canal with propagation along the right leg, which was indicated in clinical picture of spontaneous retroperitoneal haematoma. After three days the fall of hemoglobin occurred, so the additonal diagnostics was done. A computed tomography of the abdomen was performed showing well limited, large retroperitoneal hematoma (213 x 79 x 91 mm). Transfusion of concentrated red blood cells was performed twice with satisfactory correction of hemoglobin level, and four units of fresh frozen plasma. The patient was hemodynamically stabilized and discharged after a two-month long intensive care unit treatment, with the advice to use low-molecular weight heparin 2 x 0.4 mg subcutaneusly, due to persistent arrhythmia. In patients on anticoagulation therapy regular monitoring of the anticoagulant status is extremely important, because of the possibility of fatal complications development, such as retroperitoneal hematoma.

Research paper thumbnail of Retrospective evaluation of male slings for patients with urinary incontinence after radical prostatectomy - one surgeon’s experience

Acta chirurgica iugoslavica, 2014

Stress urinary incontinence is one of the main complications after radical prostatectomy (RP) wit... more Stress urinary incontinence is one of the main complications after radical prostatectomy (RP) with a significant percentage of patients reporting bothersome incontinence &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt; 1 year after surgery. Assessment of one surgeon&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39;s results in surgical treatment of urinary stress incontinence of patients with radical prostatectomy applying transobturator and suprapubic slings. From February 2010-February 2014, 20 patients, age 57-76, with moderate and severe stress urinary incontinence (SUI) were treated surgically. All patients previously had radical prostatectomy due to prostate cancer. All 20 patients with stress urinary incontinence (PRPUI) had Argus slings placement after radical prostatectomy. Patients were followed for a longer period of time, 6 months minimum, 48 months maximum.18 patients (90%) had negative, dry PAD test after surgery, one patient (5%) had positive PAD test, and one patient (5%) who previously had Advance transobturator sling placement with no positive results, had sling removed due to an infection. 6 patients (30%) needed additional sling adjustment, performed between 9-21st day after the surgery. We concluded that Argus sligs, suprapubic or transobturatory are an effective and safe treatment for PRPUI. This procedure is minimal invasive and our results clearly demonstrate that both heavy and moderate incontinence responds well.

Research paper thumbnail of Diode laser vaporization of prostate as treatment for benign prostatic enlargement: Initial results of 73 patients with 1 year follow-up

Acta chirurgica iugoslavica, 2014

Objec tive: Our ob jec tive is to eval u ate the ef ficacy, safety and 12 month out come of a 980... more Objec tive: Our ob jec tive is to eval u ate the ef ficacy, safety and 12 month out come of a 980 nm di ode la ser with Twister fi ber in the treat ment of be nign pros tatic en large ment.

Research paper thumbnail of Surgical care vesicovaginal fistulas in women with malignant gynecological disease

Acta chirurgica iugoslavica, 2014

Vesicovaginal fistulae (VVF)rep re sents one of the most fre quent com pli ca tions of var i ous ... more Vesicovaginal fistulae (VVF)rep re sents one of the most fre quent com pli ca tions of var i ous gynecolog i cal and ob stet ric pro ce dures. In pres ence of a gynecological ma lig nant tu mor, fis tula could be the out come of sur gi cal com pli ca tions, ra dio therapy or con se quence of the tu mor pro cess. Rep a ration of these fistulae is a very com plex prob lem. Our aim was to an a lyze the re sults of sur gi cal care VVF-s oc curred in women with ma lig nant gynecological dis ease which was treated sur gi cally or with radiotherapy. Out of the 48 sur gi cally treated patients with pri mary VVF, in 28 of them fis tula oc curred after hys ter ec tomy, and in 20 pa tients af ter ra dio therapy. In 15 pa tients (31.25%) transvaginal ap proach was ap plied, and in 33 pa tients (68.75%) abdominal ap proach was ap plied, with the in ter po si tion of a well vascularized lobe be ing used in 25 pa tients. All the VVFs that oc curred af ter ra dio ther apy were re paired by us ing the ab dom i nal ap proach. The ef fi ciency of sur gi cal treat ment of VVFs af ter hys ter ec tomy due to a ma lig nant dis ease was 78.5%, and af ter ra dio therapy 65%. In pa tients that have not been sub jected to ra dio ther apy, de pend ing on the char ac ter is tics of the fis tula, transvaginal or ab dom i nal ap proach is ap plica ble in VVF rep a ra tion, while the ab dom i nal approach re mains a golden stan dard in post-ra di a tion fis tula treat ment, de spite the fact that it has not solved the prob lem af ter the first med i cal treat ment in as far as 35% of pa tients.

Research paper thumbnail of Cross-Cultural Adaptation and Validation of the Serbian Version of the ICS SF Male Questionnaire

The Scientific World Journal, 2015

Introduction. The objective of this study was to cross-culturally adapt and validate ICS male SF ... more Introduction. The objective of this study was to cross-culturally adapt and validate ICS male SF questionnaire to Serbian language. Materials and Methods. This study included 91 male patients with lower urinary tract symptoms and 24 men with similar age and with confirmed absence of LUTS. ICS male SF questionnaire was translated from English to Serbian language and then back-translated to English. Results. Internal consistency was high in both dimensions, voiding (Cronbach's alpha = 0.916) and incontinence (Cronbach's alpha = 0.763). Comparison of the average scores between patients and controls revealed significant differences in both dimensions: voiding (med = 8 versus med = 0; < 0.001) and incontinence (med = 3 versus med = 0; < 0.001). Interclass correlation revealed high testretest validity in both dimensions, voiding ICC = 0.992 ( < 0.001) and incontinece ICC = 0.989 ( < 0.001). Correlation analysis revealed high agreement between ICS male SF voiding dimension and IPSS questionnaire ( = 0.943; < 0.001). Conclusion. The Serbian version of male ICS SF questionnaire showed acceptable reliability and validity. The ICS male SF questionnaire could be used in routine practice as an easy and comprehensive tool for assessment of LUTS.

Research paper thumbnail of Evaluation of compliance to local guidelines for risk factor based screening for gestational diabetes mellitus in Trebinje and Belgrade

Research paper thumbnail of Relationship between mid-trimester ultrasound fetal liver length measurements and gestational diabetes mellitus

Journal of Diabetes, 2014

The aim of the present study was to investigate the relationship between mid-trimester ultrasound... more The aim of the present study was to investigate the relationship between mid-trimester ultrasound fetal liver length (FLL) and gestational diabetes mellitus (GDM) in a high-risk population. A prospective study was performed in 331 women with singleton pregnancies who were at high risk of GDM and were undergoing a mid-trimester ultrasound examination. The ultrasound scan at 23 weeks gestation was followed by a 100-g oral glucose tolerance test (OGTT) at 24 weeks gestation. Correlations between FLL and OGTT results at different time points were tested. Receiver operating characteristic (ROC) analysis of FLL as a potential prognostic factor for GDM was also performed. In GDM patients, there was a significant positive correlation (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01) between FLL and OGTT glycemia immediately before and 60, 120, and 180 min after glucose intake. Mean FLL in GDM was significantly higher than in healthy subjects (41.04 vs 31.09 mm, respectively; P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.001). When tested as a potential prognostic factor for GDM, fetal liver measurements showed excellent diagnostic performance. The ROC analysis established a cut-off value of FLL of 39 mm for the prediction GDM, with sensitivity of 71.76%, specificity 97.56%, positive predictive value 91.0%, and negative predictive value 90.9%. The usefulness of FLL measurements was supported by a high area under the ROC curve (90.5%). In conclusion, there is a strong correlation between FLL and OGTT results, with FLL possibly serving as a valid marker for the prediction of GDM in high-risk populations.

Research paper thumbnail of Management of penile trauma caused by a dog bite

Acta chirurgica iugoslavica, 2014

Dog bites to the external genitalia are extremely rare. The literature shows only sporadic cases ... more Dog bites to the external genitalia are extremely rare. The literature shows only sporadic cases of penile injuries due to dog bites, presenting mostly as children and adolescents. We report the case of a 45-year old patient with avulsion and traumatic de-gloving of the penile skin, with exposure of the tunica albuginea, which surrounds the cavernous bodies. Dog bite wounds pose a serious medical threat. An effective initial treatment of the wound, as well as adequate supportive treatments are essential for the efficient healing of the resulting infection.

Research paper thumbnail of Pre and post test HAMA scores in women undergoing oral glucose challenge test

Research paper thumbnail of Comparative analysis of current payment system for hospital services in Serbia and projected payments under diagnostic related groups system in urology

Vojnosanitetski pregled, 2014

Background/Aim. Global budget per calendar year is a traditional method of funding hospitals in S... more Background/Aim. Global budget per calendar year is a traditional method of funding hospitals in Serbia. Diagnose related groups (DGR) is a method of hospital payment based on classification of patients into groups with clinically similar problems and similar utilization of hospital resources. The aim of this study was to compare current methods of hospital services payment with the projected costs by DRG payment method in urology. Methods. The data were obtained from the information system used in the Clinical Hospital Center "Dr. Dragiša Mišović" -Dedinje in Belgrade, Serbia. The implemented hospital information system was the main criterion for selection of healthcare institutions. The study included 994 randomly selected patients treated surgically and conservatively in 2012. Results.

Research paper thumbnail of A novel technique for treatment of mitral valve prolapse/flail

Journal of Thoracic and Cardiovascular Surgery, 2009