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Research paper thumbnail of Infections in Children with Newly Diagnosed Idiopathic Nephrotic Syndrome

Chattagram Maa-O-Shishu Hospital Medical College Journal, 2013

Patients with nephrotic syndrome (NS) are susceptible to different types of bacterial, viral & fu... more Patients with nephrotic syndrome (NS) are susceptible to different types of bacterial, viral & fungal infections. This prospective observational study was performed in the

Research paper thumbnail of A case of renal transplantation

Mymensingh medical journal : MMJ, 2008

A 12-year-old boy was admitted in paediatric nephrology unit of Bangabandhu Sheikh Mujib Medical ... more A 12-year-old boy was admitted in paediatric nephrology unit of Bangabandhu Sheikh Mujib Medical University (BSMMU) with massive proteinuria, hypertension, respiratory distress and anaemia and diagnosed as nephrotic syndrome. Percutaneous needle biopsy was consistent with diffuse endocapillary proliferative glomerulonephritis and initially managed conservatively with injection methyl prednisolone, cyclophosphamide, lisinopril etc. without any improvement. Living-related renal transplantation was done successfully from paternal uncle. Two episodes of acute rejection occurred, one immediately after transplantation and another after one month. These were managed with IV methyl prednisolone for 3 days. At present, he is on oral prednisolone, cyclosporine, azathioprine and antihypertensives with normal haemoglobin and stable serum creatinine level (pre-transplant level 12.5mg/dl to post-transplant level 1.5mg/dl). He has been maintaining his normal life including schooling for last few m...

Research paper thumbnail of Impact of etiology of chronic renal failure on growth in children

Mymensingh medical journal : MMJ, 2007

A prospective study was carried out in the Department of Pediatrics, Bangabandhu Sheikh Mujib Med... more A prospective study was carried out in the Department of Pediatrics, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh, from October, 2001 to October, 2003 to find out the impact of different etiology of chronic renal failure on growth in children. Fifty children of both sexes under 15 years of age with clinical and biochemical evidence of chronic renal failure (CRF) with creatinine clearance (Ccr) of <75 ml/min/1.73m2 were included in the study. On the basis of underlying causes of CRF, the children were divided into congenital (n=30) and acquired (n=20) groups. All patients' height, weight, radiographs of different bones was obtained to evaluate the presence of renal osteodystrophy (ROD) and for assessment of bone age. Serum intact parathormone (iPTH) level was also assayed in all patients. These parameters were evaluated in two groups. CRF children due to congenital anomalies had stunting and wasting in 23 (76.7%) and 20 (66.7%) cases respectively and ...

Research paper thumbnail of Complimentary Feeding Practices in Under-2 Children

Chattagram Maa-O-Shishu Hospital Medical College Journal, 2014

Background: Complimentary feeding (CF) practices are quiet frustating in our country. Innaproprit... more Background: Complimentary feeding (CF) practices are quiet frustating in our country. Innaproprite foods in first two years of life have detrimental impact on health and growth of children. The aim of the study was to see the present pattern of CF practices, to identify wrong practices and to develop awareness among medical professionals so that they may encourage appropriate practices more vigorously for reducing child mortality and morbidity.Methods: A cross-sectional study was conducted from October, 2011 to December, 2011 in the Pediatric department (indoor and outdoor) of Sir Salimullah Medical College Mitford Hospital, Dhaka and in a private chamber of a district town of Bangladesh. Four hundred motherchild pairs were selected by non-random convenience sampling method. 6-24 months old children and children under six months (if was on complimentary feeding) were included. Data was collected from the mothers/caregivers of the children in a pretested semi-structured data collect...

Research paper thumbnail of Long versus standard initial prednisolone therapy in children with idiopathic nephrotic syndrome

Mymensingh medical journal : MMJ, 2014

The efficacy of longer initial course of prednisolone with standard regimen was compared in child... more The efficacy of longer initial course of prednisolone with standard regimen was compared in children with idiopathic nephrotic syndrome (INS). It was a randomized controlled trial in which patients with INS who responded to initial course of prednisolone, either long or standard regimen were included and followed for one year after completion of treatment of first attack. The long regimen consisted of prednisolone 60mg/m²/day for six weeks followed by 40mg/m² every alternate day single morning dose for further six weeks. The standard regimen consisted of prednisolone 60mg/m²/day for four weeks followed by 40mg/m² every alternate day single morning dose for further four weeks. There were 93 children who fulfilled the criteria of the study, 47 from long group and 46 from standard group though ultimately 72 completed the study (41 from long and 31 from standard group). The primary outcome measure was relapse within next one year. Relapse within one year was noted in 73.2% of long and 6...

Research paper thumbnail of Infections in Children with Newly Diagnosed Idiopathic Nephrotic Syndrome

Chattagram Maa-O-Shishu Hosp. Med. College J. , 2013

Patients with nephrotic syndrome (NS) are susceptible to different types of bacterial, viral & fu... more Patients with nephrotic syndrome (NS) are susceptible to different types of bacterial, viral & fungal infections. This prospective observational study was performed in the

Research paper thumbnail of Complimentary Feeding Practices in Under-2 Children

Chattagram Maa-O-Shishu Hospital Medical College Journal, 2014

Background: Complimentary feeding (CF) practices are quiet frustating in our country. Innaproprit... more Background: Complimentary feeding (CF) practices are quiet frustating in our country. Innaproprite foods in first two years of life have detrimental impact on health and growth of children. The aim of the study was to see the present pattern of CF practices, to identify wrong practices and to develop awareness among medical professionals so that they may encourage appropriate practices more vigorously for reducing child mortality and morbidity. Methods: A cross-sectional study was conducted from October, 2011 to December, 2011 in the Pediatric department (indoor and outdoor) of Sir Salimullah Medical College Mitford Hospital, Dhaka and in a private chamber of a district town of Bangladesh. Four hundred motherchild pairs were selected by non-random convenience sampling method. 6-24 months old children and children under six months (if was on complimentary feeding) were included. Data was collected from the mothers/caregivers of the children in a pretested semi-structured data collection sheet and analyzed by SPSS version 12. Appropriate statistical tests were done. Statistical significance was considered if p value was <0.05. Results: Early initiation was very high (49.25%). Most common first complimentary food was rice gruel with milk (26.56%). Most common current main complimentary food (25.52%) and most common main complimentary food fed in last 24 hours (26.82%) was also rice gruel with milk. Amount of complimentary food per feed was inappropriate in most cases. Frequency of CF was not appropriate in many cases. Fast foods and commercial cereal were given to 54.8% & 33.33% children respectively. Only 1% mothers/caregivers had sound knowledge about CF. Positive support from family regarding practicing appropriate CF was found in 24.75% cases. Feeding practices were mostly influenced by relatives (25%). Conclusion: CF practices are still not ideal in our country. So, all possible interventions should be applied to improve it and thus to improve child survival.

Research paper thumbnail of Nephrogenic Diabetes Insipidus (NDI): a Rare Presentation in Early Infancy-A Case Report

Bangladesh Medical Journal, 2012

A 30 months old boy presented with polyuria and polydipsia since 6 months of age. There was no fa... more A 30 months old boy presented with polyuria and polydipsia since 6 months of age. There was no family history of similar illness. Investigations revealed serum hyperosmolarity and normal renal function. Diagnostic findings correlated with nephrogenic diabetis insipidus (NDI) as the patient was non-responsive to vasopressin in water deprivation test. MRI of brain was normal and ultrasonogram of kidney, ureter, and urinary bladder was normal and other investigations showed no abnormality.

Research paper thumbnail of Barriers of Appropriate Complementary Feeding Practices in Under -2 Children

Journal of Bangladesh College of Physicians and Surgeons, 2015

When breast milk is no longer enough to meet the nutritional needs of infants, complementary food... more When breast milk is no longer enough to meet the nutritional needs of infants, complementary foods should be added to their diet. It is a very vulnerable period when malnutrition starts in many infants, contributing significantly to high prevalence of malnutrition in under-5 children worldwide. In Bangladesh, complementary feeding (CF) practices are not satisfactory. The objectives of the study were to look into the feeding patterns of under-2 children and to identify the causes which lead mothers/ caregivers to practice inappropriate CF. This cross-sectional study was done in the Pediatric department of Sir Salimullah Medical College Mitford Hospital, Dhaka and in a private chamber from a district town of Bangladesh from October, 2011 to December, 2011. Four hundred mother-child pairs were enrolled by non-random convenience sampling. Different aspects of feeding practices (age of initiation of CF, type of first complementary food, current main complementary food & its quantity, and frequency of CF) were analyzed. Bottle feeding, fast foods and lack of proper family support were most important barriers (p<0.05). High rate of early initiation of CF was mainly due to mothers' perception that breast milk alone was not enough (81.8%) and main cause of late initiation was refusal of complementary foods by their babies (48.4%). Feeding practices were mainly influenced by relatives (25%), qualified doctors (15.3%), neighbors (14.5%) & mother-in-laws (13.5%). CF practices are still far from ideal. Strengthening of nutrition education to mothers/caregivers and family members/relatives along with awareness building in the community may change the wrong practices.

Research paper thumbnail of Clinical Presentations and Outcome of Acute Glomerulonephritis in Children

Bangladesh Medical Journal, 2019

Acute post streptococcal glomerulonephritis (APSGN) is the most common type of acute glomerulonep... more Acute post streptococcal glomerulonephritis (APSGN) is the most common type of acute glomerulonephritis (AGN) in childhood. It has not been studied well in Bangladesh. To evaluate the clinical characteristics, complications and outcome of Acute post streptococcal glomerulonephritis (AGN). the

Research paper thumbnail of Infections in Children with Newly Diagnosed Idiopathic Nephrotic Syndrome

Chattagram Maa-O-Shishu Hospital Medical College Journal, 2013

Patients with nephrotic syndrome (NS) are susceptible to different types of bacterial, viral & fu... more Patients with nephrotic syndrome (NS) are susceptible to different types of bacterial, viral & fungal infections. This prospective observational study was performed in the

Research paper thumbnail of A case of renal transplantation

Mymensingh medical journal : MMJ, 2008

A 12-year-old boy was admitted in paediatric nephrology unit of Bangabandhu Sheikh Mujib Medical ... more A 12-year-old boy was admitted in paediatric nephrology unit of Bangabandhu Sheikh Mujib Medical University (BSMMU) with massive proteinuria, hypertension, respiratory distress and anaemia and diagnosed as nephrotic syndrome. Percutaneous needle biopsy was consistent with diffuse endocapillary proliferative glomerulonephritis and initially managed conservatively with injection methyl prednisolone, cyclophosphamide, lisinopril etc. without any improvement. Living-related renal transplantation was done successfully from paternal uncle. Two episodes of acute rejection occurred, one immediately after transplantation and another after one month. These were managed with IV methyl prednisolone for 3 days. At present, he is on oral prednisolone, cyclosporine, azathioprine and antihypertensives with normal haemoglobin and stable serum creatinine level (pre-transplant level 12.5mg/dl to post-transplant level 1.5mg/dl). He has been maintaining his normal life including schooling for last few m...

Research paper thumbnail of Impact of etiology of chronic renal failure on growth in children

Mymensingh medical journal : MMJ, 2007

A prospective study was carried out in the Department of Pediatrics, Bangabandhu Sheikh Mujib Med... more A prospective study was carried out in the Department of Pediatrics, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh, from October, 2001 to October, 2003 to find out the impact of different etiology of chronic renal failure on growth in children. Fifty children of both sexes under 15 years of age with clinical and biochemical evidence of chronic renal failure (CRF) with creatinine clearance (Ccr) of <75 ml/min/1.73m2 were included in the study. On the basis of underlying causes of CRF, the children were divided into congenital (n=30) and acquired (n=20) groups. All patients' height, weight, radiographs of different bones was obtained to evaluate the presence of renal osteodystrophy (ROD) and for assessment of bone age. Serum intact parathormone (iPTH) level was also assayed in all patients. These parameters were evaluated in two groups. CRF children due to congenital anomalies had stunting and wasting in 23 (76.7%) and 20 (66.7%) cases respectively and ...

Research paper thumbnail of Complimentary Feeding Practices in Under-2 Children

Chattagram Maa-O-Shishu Hospital Medical College Journal, 2014

Background: Complimentary feeding (CF) practices are quiet frustating in our country. Innaproprit... more Background: Complimentary feeding (CF) practices are quiet frustating in our country. Innaproprite foods in first two years of life have detrimental impact on health and growth of children. The aim of the study was to see the present pattern of CF practices, to identify wrong practices and to develop awareness among medical professionals so that they may encourage appropriate practices more vigorously for reducing child mortality and morbidity.Methods: A cross-sectional study was conducted from October, 2011 to December, 2011 in the Pediatric department (indoor and outdoor) of Sir Salimullah Medical College Mitford Hospital, Dhaka and in a private chamber of a district town of Bangladesh. Four hundred motherchild pairs were selected by non-random convenience sampling method. 6-24 months old children and children under six months (if was on complimentary feeding) were included. Data was collected from the mothers/caregivers of the children in a pretested semi-structured data collect...

Research paper thumbnail of Long versus standard initial prednisolone therapy in children with idiopathic nephrotic syndrome

Mymensingh medical journal : MMJ, 2014

The efficacy of longer initial course of prednisolone with standard regimen was compared in child... more The efficacy of longer initial course of prednisolone with standard regimen was compared in children with idiopathic nephrotic syndrome (INS). It was a randomized controlled trial in which patients with INS who responded to initial course of prednisolone, either long or standard regimen were included and followed for one year after completion of treatment of first attack. The long regimen consisted of prednisolone 60mg/m²/day for six weeks followed by 40mg/m² every alternate day single morning dose for further six weeks. The standard regimen consisted of prednisolone 60mg/m²/day for four weeks followed by 40mg/m² every alternate day single morning dose for further four weeks. There were 93 children who fulfilled the criteria of the study, 47 from long group and 46 from standard group though ultimately 72 completed the study (41 from long and 31 from standard group). The primary outcome measure was relapse within next one year. Relapse within one year was noted in 73.2% of long and 6...

Research paper thumbnail of Infections in Children with Newly Diagnosed Idiopathic Nephrotic Syndrome

Chattagram Maa-O-Shishu Hosp. Med. College J. , 2013

Patients with nephrotic syndrome (NS) are susceptible to different types of bacterial, viral & fu... more Patients with nephrotic syndrome (NS) are susceptible to different types of bacterial, viral & fungal infections. This prospective observational study was performed in the

Research paper thumbnail of Complimentary Feeding Practices in Under-2 Children

Chattagram Maa-O-Shishu Hospital Medical College Journal, 2014

Background: Complimentary feeding (CF) practices are quiet frustating in our country. Innaproprit... more Background: Complimentary feeding (CF) practices are quiet frustating in our country. Innaproprite foods in first two years of life have detrimental impact on health and growth of children. The aim of the study was to see the present pattern of CF practices, to identify wrong practices and to develop awareness among medical professionals so that they may encourage appropriate practices more vigorously for reducing child mortality and morbidity. Methods: A cross-sectional study was conducted from October, 2011 to December, 2011 in the Pediatric department (indoor and outdoor) of Sir Salimullah Medical College Mitford Hospital, Dhaka and in a private chamber of a district town of Bangladesh. Four hundred motherchild pairs were selected by non-random convenience sampling method. 6-24 months old children and children under six months (if was on complimentary feeding) were included. Data was collected from the mothers/caregivers of the children in a pretested semi-structured data collection sheet and analyzed by SPSS version 12. Appropriate statistical tests were done. Statistical significance was considered if p value was <0.05. Results: Early initiation was very high (49.25%). Most common first complimentary food was rice gruel with milk (26.56%). Most common current main complimentary food (25.52%) and most common main complimentary food fed in last 24 hours (26.82%) was also rice gruel with milk. Amount of complimentary food per feed was inappropriate in most cases. Frequency of CF was not appropriate in many cases. Fast foods and commercial cereal were given to 54.8% & 33.33% children respectively. Only 1% mothers/caregivers had sound knowledge about CF. Positive support from family regarding practicing appropriate CF was found in 24.75% cases. Feeding practices were mostly influenced by relatives (25%). Conclusion: CF practices are still not ideal in our country. So, all possible interventions should be applied to improve it and thus to improve child survival.

Research paper thumbnail of Nephrogenic Diabetes Insipidus (NDI): a Rare Presentation in Early Infancy-A Case Report

Bangladesh Medical Journal, 2012

A 30 months old boy presented with polyuria and polydipsia since 6 months of age. There was no fa... more A 30 months old boy presented with polyuria and polydipsia since 6 months of age. There was no family history of similar illness. Investigations revealed serum hyperosmolarity and normal renal function. Diagnostic findings correlated with nephrogenic diabetis insipidus (NDI) as the patient was non-responsive to vasopressin in water deprivation test. MRI of brain was normal and ultrasonogram of kidney, ureter, and urinary bladder was normal and other investigations showed no abnormality.

Research paper thumbnail of Barriers of Appropriate Complementary Feeding Practices in Under -2 Children

Journal of Bangladesh College of Physicians and Surgeons, 2015

When breast milk is no longer enough to meet the nutritional needs of infants, complementary food... more When breast milk is no longer enough to meet the nutritional needs of infants, complementary foods should be added to their diet. It is a very vulnerable period when malnutrition starts in many infants, contributing significantly to high prevalence of malnutrition in under-5 children worldwide. In Bangladesh, complementary feeding (CF) practices are not satisfactory. The objectives of the study were to look into the feeding patterns of under-2 children and to identify the causes which lead mothers/ caregivers to practice inappropriate CF. This cross-sectional study was done in the Pediatric department of Sir Salimullah Medical College Mitford Hospital, Dhaka and in a private chamber from a district town of Bangladesh from October, 2011 to December, 2011. Four hundred mother-child pairs were enrolled by non-random convenience sampling. Different aspects of feeding practices (age of initiation of CF, type of first complementary food, current main complementary food & its quantity, and frequency of CF) were analyzed. Bottle feeding, fast foods and lack of proper family support were most important barriers (p<0.05). High rate of early initiation of CF was mainly due to mothers' perception that breast milk alone was not enough (81.8%) and main cause of late initiation was refusal of complementary foods by their babies (48.4%). Feeding practices were mainly influenced by relatives (25%), qualified doctors (15.3%), neighbors (14.5%) & mother-in-laws (13.5%). CF practices are still far from ideal. Strengthening of nutrition education to mothers/caregivers and family members/relatives along with awareness building in the community may change the wrong practices.

Research paper thumbnail of Clinical Presentations and Outcome of Acute Glomerulonephritis in Children

Bangladesh Medical Journal, 2019

Acute post streptococcal glomerulonephritis (APSGN) is the most common type of acute glomerulonep... more Acute post streptococcal glomerulonephritis (APSGN) is the most common type of acute glomerulonephritis (AGN) in childhood. It has not been studied well in Bangladesh. To evaluate the clinical characteristics, complications and outcome of Acute post streptococcal glomerulonephritis (AGN). the