Baha Arslan - Academia.edu (original) (raw)

Papers by Baha Arslan

Research paper thumbnail of Laparoscopic Approach to Giant Over Cysts and Case Report

Bezmialem Science, 2018

Abdominal kitlelere yaklaşım belirlenirken tümörün davranışı önemli ölçüde rol oynar. Benign oldu... more Abdominal kitlelere yaklaşım belirlenirken tümörün davranışı önemli ölçüde rol oynar. Benign olduğu düşünülen olgularda minimal invaziv cerrahi hasta ve cerrah konforu için değerli bir yaklaşımdır. Burada karında şişlik nedeni ile kliniğimize başvuran ve tetkiklerinde mezenterik kist ve over kisti ayırımı tam yapılamayan premenapozal kadın hastaya laparoskopik cerrahi yaklaşım literatür eşliğinde incelenmiştir.

Research paper thumbnail of Can Cholecystectomy Be Performed as Safely in Elderly Patients as It is in Young Patients

The Turkish Journal of Geriatrics, 2020

In this study, we aimed to compare the surgical outcomes between elderly and young patients under... more In this study, we aimed to compare the surgical outcomes between elderly and young patients undergoing surgery for gallstone disease and determine variations in patient characteristics, if any. Materials and Method: Data of patients who underwent surgery for gallstone disease at a single center between 2010 and 2018 were analyzed retrospectively. Two patient groups were evaluated: patients <65 years and ≥65 years. Patient characteristics, preoperative outpatient clinic data, surgical data, and postoperative data were collected. Results: In total, 1,198 patients with a mean age of 54.77 ± 15.03 (15-91) years were assessed. Comorbid conditions, including cardiovascular disease, pulmonary disease, renal disease, and diabetes mellitus were significantly more common in elderly patients (p<0.001). Acute cholecystitis in the preoperative period was noted in 15.36% of young patients and in 30.4% of elderly patients (p<0.001). Need for emergency surgery was higher in elderly patients than in young patients [13.86% (47) and 9.31% (80), respectively] (p=0.021). Laparoscopic cholecystectomy and open cholecystectomy were performed in 98.37% and 1.04% of young patients, respectively, and in 92.62% and 3.53% of elderly patients, respectively (p<0.001). Among factors affecting the length of hospital stay in elderly patients, the duration of hospitalization was significantly longer in elderly patients who underwent emergency surgery, open surgery, needed additional surgery, and who had high American Society of Anesthesiologists scores (p<0.001, p<0.001, p=0.013, p<0.001, respectively). Conclusion: Complications rates associated with cholecystectomy are similar between young and elderly patients when appropriate surgical preparations are performed. Surgery for gallstone disease can be performed safely in elderly patients with low morbidity and mortality rates.

Research paper thumbnail of Retrorektal Kitle Nedeni ile Multidisipliner Yaklafl›m Yap›lan Bir Olgu Sunumu A Case Presentation of a Retrorectal Mass Managed in a Multidisciplinary Method

The retrorectal masses belong in a large spectrum cases that from neurological masses to inflamat... more The retrorectal masses belong in a large spectrum cases that from neurological masses to inflamatuar process which are infrequent illness that most of surgeons are encountered in a part of their career. Usually surgery is the specific remedy method. In this study the case which was remedied by multidisciplinary method for retrorectal mass is presented.

Research paper thumbnail of Benefits and reliability of laparoscopic sleeve gastrectomy in patients aged 60 years and older

Annals of Medical Research, 2019

Aim: Obesity is a disease that reduces the quality and duration of life and its prevalence is als... more Aim: Obesity is a disease that reduces the quality and duration of life and its prevalence is also increasing in the elderly population.In this study, we aimed to investigate the results of early and midterm weight loss and treatment of concomitant diseases and evaluate the safety and efficacy of bariatric surgery in patients aged 60 years and older who underwent Laparoscopic Sleeve Gastrectomy (LSG) in our clinic. Material and Methods: We retrospectively evaluated 28 morbid obese patients ≥60 years oldwho underwent LSG between September 2014 and January 2018.Data reviewed included age, sex, preoperative weight and body mass index (BMI), comorbid conditions, early or delayed complications, mortality, length of follow-up, weight lost, BMI points lost, and effects on obesity-related comorbid conditions. Results: Of 28 patients included in the study there were 22 (78.6%) females and 6 (21.4%) males. The average age of patients was 63.4±3.39.Preoperative mean BMI was 48.4±7.0kg/m2.Ave...

Research paper thumbnail of The effect of amniotic membrane wrapping on colorectal anastomosis in rats undergoing pelvic radiotherapy

Annals of Medical Research, 2020

Aim: This study aimed to investigate the effect of amniotic membrane wrapped onto the anastomosis... more Aim: This study aimed to investigate the effect of amniotic membrane wrapped onto the anastomosis line following colon resection and primary anastomosis on anastomosis healing in rats undergoing pelvic radiotherapy. Material and Methods: Fifty-six male Wistar albino rats were randomly allocated to four main groups. Group I, left colon resection and primary anastomosis; Group II, post-anastomotic amniotic membrane; Group III, preoperative radiotherapy; Group IV, preoperative radiotherapy and amniotic membrane. Radiotherapy was administered under general anesthesia eight and four days prior to surgery at a total of 20 Gy. In the first operation, all the rats underwent 1 cm left colon resection and primary anastomosis. The animals in each group were anesthetized to assess the clinical, mechanical, histologic, and biochemical parameters of anastomotic healing on the third and seventh postoperative days. Results: In the third day groups, anastomosis line bursting was observed in only one subject in those undergoing amniotic membrane wrapping(p<0.05) and in all rats in those with no amniotic membrane wrapping. No statistically significant difference was observed in any of the parameters on the histopathological examination of the day 3 groups. The amounts of granulation tissue and fibroblast were significantly higher in the post-anastomotic amniotic membrane group (p<0.05), and the macrophage amount was seen to be significantly low in both amniotic membrane groups (p<0.05). Conclusion: Amniotic membrane application on the anastomoses in the intestines, either with or without radiotherapy, may contribute to wound healing by positively affecting the anastomosis health.

Research paper thumbnail of A retrospective comparison of the results of wide excision-lay open, primary closure and flap application in surgical treatment for primary pilonidal sinus disease

Ege Tıp Dergisi, 2019

Amaç: Bu çalışmada primer pilonidal sinüs nedeni ile ameliyat edilen hastalarda geniş eksizyon so... more Amaç: Bu çalışmada primer pilonidal sinüs nedeni ile ameliyat edilen hastalarda geniş eksizyon sonrası açık bırakma (GE), geniş eksizyon primer kapama (PK) ve flep uygulaması (F) yapılan hastaların sonuçlarının karşılaştırılması planlandı. Gereç ve Yöntem: Toplam 249 hastanın verileri retrospektif olarak değerlendirildi. Bu hastaların 12’si nüks hastalık nedeni ile değerlendirme dışı bırakıldı. Hastaların 101’ine GE, 68’ine PK ve 68’ine de F yapılmıştı. Demografik özellikler, semptomların süresi, gluteal kleftin özelliği, perioperatif komplikasyonlar, ameliyat süresi ve hastanede kalış süresi, dren kullanımı ve pansuman durumu patolojik piyes hacmi anüse uzaklık ve hastalığın nüksü kaydedildi. Bulgular: Ortalama operasyon süresi GE grubunda 32,62±9,65; PK grubunda 53,23±15,40; F grubunda 76,69±17,00 dakika idi (p

Research paper thumbnail of Appendiceal intussusception, a peroperative surprise: A case report

Journal of Surgery and Medicine, 2019

Intussusception of the appendix is very uncommon and when encountered, it may alter surgical proc... more Intussusception of the appendix is very uncommon and when encountered, it may alter surgical procedures. For this reason, it should be kept in mind that appendiceal intussusception may occur in every patient diagnosed with acute appendicitis. It is critical to consider appendiceal intussusception in patients presenting with recurrent nausea, vomiting and chronic abdominal pain.

Research paper thumbnail of Comparison of Resection and Liver Transplant in Treatment of Hepatocellular Carcinoma

Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, Jan 28, 2018

Hepatic resection and liver transplant are regarded as 2 potentially curative treatments for hepa... more Hepatic resection and liver transplant are regarded as 2 potentially curative treatments for hepatocellular carcinoma. Here, we compared both options in patients with hepatocellular carcinoma secondary to cirrhosis seen at a single center over 12 years. We evaluated early complications and survival of patients with hepatocellular carcinoma treated with liver transplant (57 patients) or hepatic resection (36 patients) at our center between 1998 and 2010. The 34-month mean follow-up period was similar for both treatment groups. The liver transplant group had a longer hospital stay than the hepatic resection group (P ⟨ .001). Patients with Child-Turcotte-Pugh A stage were treated by hepatic resection more than by liver transplant (P ⟨ .001),with Child-Turcotte-Pugh B stage patients treated by liver transplant more than by hepatic resection (P = .03). All patients with Child-Turcotte-Pugh C stage had liver transplant. Both treatment groups had similar postoperative complications and ear...

Research paper thumbnail of AAsymptomatic cholecysto-enteric fistula and gallstone ileus: Two case reports

Annals of Medical Research, 2018

Research paper thumbnail of Diagnostic Accuracy of Axillary Ultrasound in Early–Stage Breast Cancer

Indian Journal of Surgery, 2018

Sentinel lymph node biopsy is the standard application for evaluating the axilla in patients with... more Sentinel lymph node biopsy is the standard application for evaluating the axilla in patients with breast cancer. The Z0011 trial conducted by The American College of Surgeons Oncology Group (ACOSOG) revealed that axillary dissection may be redundant in selected patients with positive sentinel node. This raises questions regarding the application of this result to ultrasoundpositive patients. This research therefore aimed to evaluate how accurate an ultrasound scan is for axillary node status in earlystage breast carcinoma. The study included 156 newly diagnosed clinical T1-T2, N0 breast cancer patients attending our breast clinic between January 2010 and February 2016. Sentinel lymph node biopsy and axillary lymph node clearance in the presence of sentinel lymph node metastasis was performed on all the breast cancer patients. Axillary ultrasound reports were reviewed retrospectively and the results compared with surgical pathology results. The sensitivity and specificity of axillary ultrasound for detecting axillary lymph node disease was 69.2% and 98%, respectively, with a negative predictive value of 86.4% and positive predictive value of 94.7%. Given the high sensitivity and specificity, and high positive predictive value and negative predictive value demonstrated in the present study, axillary ultrasound represents a potential alternative to sentinel lymph node biopsy for staging of the axilla in early breast cancer. Subsequent trials (SOUND) comparing axillary ultrasound alone with sentinel lymph node biopsy in early breast cancer patients will provide additional information about the subject.

Research paper thumbnail of Changes in serum lipid levels after laparoscopic sleeve gastrectomy in morbidly obese dyslipidemic and normolipidemic patients

Acta chirurgica Belgica, Jan 17, 2017

This study investigated the effect of laparoscopic sleeve gastrectomy (LSG) performed for morbid ... more This study investigated the effect of laparoscopic sleeve gastrectomy (LSG) performed for morbid obesity on serum lipid levels of dyslipidemic and normolipidemic patients. 141 patients who underwent LSG between September 2014 and January 2016 were included in the study. The patients' mean body mass index was 46.27 ± 6.79 kg/mpreoperatively, 31.60 ± 5.37 kg/min the 6th month postoperatively and 27.80 ± 4.25 kg/min the 12th month (p < .001). Preoperatively and 12 months after the operation, mean total cholesterol (TC) levels and mean LDL cholesterol, mean HDL cholesterol, and mean triglyceride (TG) levels were statistically significantly decreased (p < .01). Comparing TC levels in the 12th month with preoperative levels, dyslipidemic patients showed a statistically more significant decrease than normolipidemic patients. LDL cholesterol levels were significantly decreased in both the groups. HDL cholesterol levels increased significantly in both groups while mean TG levels de...

Research paper thumbnail of A case presentation of retrorectal mass approached by multidisciplinary method

Journal of Turkish Association of Colorectal Surgeons, 2011

Research paper thumbnail of Expression and activity levels of matrix metalloproteinase-7 and in situ localization of caseinolytic activity in colorectal cancer

Clinical Biochemistry, 2014

In situ casein zymography Colorectal cancer Objectives: Matrix metalloproteinase-7 is capable of ... more In situ casein zymography Colorectal cancer Objectives: Matrix metalloproteinase-7 is capable of degrading several ECM and non-ECM molecules and contributes to colorectal cancer progression and metastasis. Here, we examined the significance of MMP-7 in colorectal tumors by detecting active and latent MMP-7 levels and localization of its caseinolytic activity. Design and methods: We investigated expression levels, localization, and proteolytic activity of MMP-7 and local caseinolytic activity in colorectal tumor and paired normal tissues by using real time PCR, casein zymography, immunohistochemistry and in situ casein zymography, respectively. In addition the results were compared with clinicopathological variables. Results: Real time PCR and immunohistochemistry showed that MMP-7 expressions were higher in colorectal tumor tissues than in normal tissues. Also, mRNA expressions of MMP-7 were positively correlated with tumor and pathological stages and negatively correlated with age. Furthermore, MMP-7 mRNA expression had a sensitivity of 81.3% and a specificity of 81.2% at a cutoff value of 0.0006, making it a potential marker for diagnosis of colorectal cancer. According to casein zymography, pro-and active MMP-7 levels were also elevated in tumor tissues. In addition, we assessed local caseinolytic activity using in situ casein zymography. Increased immunoreactivity of MMP-7 and local caseinolytic activity were found in neoplastic cells but not in stromal cells. Conclusion: We emphasized the significant role of MMP-7 in diagnosis and progression and/or development of colorectal cancer.

Research paper thumbnail of Five years with a rectal foreign body: A case report

International Journal of Surgery Case Reports, 2015

Research paper thumbnail of Karaciğer Nakli Sonrası İnsizyonel Herni Onarım Sonuçları

Turkiye Klinikleri Journal of Medical Sciences, 2012

Bu olgu serisinde karaciğer nakli sonrası oluşan insizyonel hernilerde risk faktörleri, onarım şe... more Bu olgu serisinde karaciğer nakli sonrası oluşan insizyonel hernilerde risk faktörleri, onarım şekilleri ve sonuçları sunulmaktadır. G Ge er re eç ç v ve e Y Yö ön nt te em ml le er r: : Ortotopik karaciğer nakli yapılan 362 hastanın kayıtları retrospektif olarak incelendi. Bu çalışma tanımlayıcı bir çalışma olarak tasarlandı ve herhangi bir istatistiksel yöntem kullanılmadı. Sonuçlar ortalama±standart sapma ve sayı (%) olarak verildi. Çalışmaya karaciğer nakli sonrası en az bir yıl izlenen hastalar alındı. İlk altı ay içinde ölen 57 (%15,7) hasta çalışma dışı bırakıldı. İnsizyonel herni ortaya çıkan dokuz hastanın risk faktörleri, defekt büyüklükleri, kullanılan yamalar ve onarım şekilleri incelendi. B Bu ul lg gu ul la ar r: : Çalışmaya alınan 305 hastanın dokuzunda (%2,9) insizyonel herni saptandı. Bu hastalarda en sık karaciğer nakil endikasyonu kronik hepatit C'ye bağlı sirozdu. Karaciğer nakli sonrası bu dokuz hastanın dördünde (%44,4) komplikasyon (duodenal ülser perforasyonu, hepatik arter anastomozundan kanama, duodenal ülserden kanama ve mekanik bağırsak tıkanıklığı) gelişti. Dokuz hastanın üçüne relaparotomi uygulandı. Defektin en büyük çapının ortalaması 27,9±10,1 (6-40) cm idi. İnsizyonel herni onarımlarında en sık expanded-politetrafluoroetilen yama kullanıldı. Bir hastada oluşan nüks insizyonel herni dışında erken ve geç dönemde komplikasyon ortaya çıkmadı. S So on nu uç ç: : İnsizyonel herni oluşumu için ek risk faktörlerine sahip sirozlu hastalarda, karaciğer nakli sonrasında uygun kapatılma tekniği ve materyalleri kullanılarak insizyonel herni gelişimi azaltılabilir, insizyonel herni gelişen hastalarda ise uygun yamalar ve teknik kullanılarak güvenle onarım yapılabilir. A An na ah ht ta ar r K Ke el li im me el le er r: : Fıtık, abdominal; karaciğer transplantasyonu; immünosupresyon A AB BS ST TR RA AC CT T O Ob bj je ec ct ti iv ve e: : In this case series, the risk factors, types of repair and outcomes for the development of incisional hernias following liver transplantation are presented. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : The medical records of 362 patients who underwent orthotopic liver transplantation were analyzed retrospectively. This study was designed as a descriptive study and statistical methods were not used. Results were given as mean ± standard deviation and number (%). Patients who were followed up for at least one year after liver transplantation were included in the study. Fiftyseven (15.7%) patients who died within the first six months were excluded. The risk factors, defect size, meshes used and types of repair were analyzed in nine patients who developed incisional hernia. R Re es su ul lt ts s: : Incisional hernia was detected in nine (2.9%) out of 305 patients included in the study. The most common indication for liver transplantation was cirrhosis due to chronic viral hepatitis C. Complications (duodenal ulcer perforation, bleeding from hepatic artery anastomosis, bleeding from duodenal ulcer and mechanical intestinal obstruction) developed in four (44.4%) of these nine patients after liver transplantation. Relaparatomy was performed in three of nine patients. The mean largest diameter of defect was 27.9 ± 10.1 (6-40) cm. Expanded-polytetrafluoroethylene mesh was used most frequently for incisional hernia repair. Early or late complications did not develop except one patient who developed recurrent incisional hernia. C Co on nc cl lu us si io on n: : In cirrhotic patients who have additional risk factors for incisional hernia development, the risk of hernia development may be reduced by using appropriate closure technique and materials after liver transplantation. A safe hernia repair may be performed by using an appropriate technique and meshes if the patient develops an incisional hernia.

Research paper thumbnail of Laparoscopic Approach to Giant Over Cysts and Case Report

Bezmialem Science, 2018

Abdominal kitlelere yaklaşım belirlenirken tümörün davranışı önemli ölçüde rol oynar. Benign oldu... more Abdominal kitlelere yaklaşım belirlenirken tümörün davranışı önemli ölçüde rol oynar. Benign olduğu düşünülen olgularda minimal invaziv cerrahi hasta ve cerrah konforu için değerli bir yaklaşımdır. Burada karında şişlik nedeni ile kliniğimize başvuran ve tetkiklerinde mezenterik kist ve over kisti ayırımı tam yapılamayan premenapozal kadın hastaya laparoskopik cerrahi yaklaşım literatür eşliğinde incelenmiştir.

Research paper thumbnail of Can Cholecystectomy Be Performed as Safely in Elderly Patients as It is in Young Patients

The Turkish Journal of Geriatrics, 2020

In this study, we aimed to compare the surgical outcomes between elderly and young patients under... more In this study, we aimed to compare the surgical outcomes between elderly and young patients undergoing surgery for gallstone disease and determine variations in patient characteristics, if any. Materials and Method: Data of patients who underwent surgery for gallstone disease at a single center between 2010 and 2018 were analyzed retrospectively. Two patient groups were evaluated: patients <65 years and ≥65 years. Patient characteristics, preoperative outpatient clinic data, surgical data, and postoperative data were collected. Results: In total, 1,198 patients with a mean age of 54.77 ± 15.03 (15-91) years were assessed. Comorbid conditions, including cardiovascular disease, pulmonary disease, renal disease, and diabetes mellitus were significantly more common in elderly patients (p<0.001). Acute cholecystitis in the preoperative period was noted in 15.36% of young patients and in 30.4% of elderly patients (p<0.001). Need for emergency surgery was higher in elderly patients than in young patients [13.86% (47) and 9.31% (80), respectively] (p=0.021). Laparoscopic cholecystectomy and open cholecystectomy were performed in 98.37% and 1.04% of young patients, respectively, and in 92.62% and 3.53% of elderly patients, respectively (p<0.001). Among factors affecting the length of hospital stay in elderly patients, the duration of hospitalization was significantly longer in elderly patients who underwent emergency surgery, open surgery, needed additional surgery, and who had high American Society of Anesthesiologists scores (p<0.001, p<0.001, p=0.013, p<0.001, respectively). Conclusion: Complications rates associated with cholecystectomy are similar between young and elderly patients when appropriate surgical preparations are performed. Surgery for gallstone disease can be performed safely in elderly patients with low morbidity and mortality rates.

Research paper thumbnail of Retrorektal Kitle Nedeni ile Multidisipliner Yaklafl›m Yap›lan Bir Olgu Sunumu A Case Presentation of a Retrorectal Mass Managed in a Multidisciplinary Method

The retrorectal masses belong in a large spectrum cases that from neurological masses to inflamat... more The retrorectal masses belong in a large spectrum cases that from neurological masses to inflamatuar process which are infrequent illness that most of surgeons are encountered in a part of their career. Usually surgery is the specific remedy method. In this study the case which was remedied by multidisciplinary method for retrorectal mass is presented.

Research paper thumbnail of Benefits and reliability of laparoscopic sleeve gastrectomy in patients aged 60 years and older

Annals of Medical Research, 2019

Aim: Obesity is a disease that reduces the quality and duration of life and its prevalence is als... more Aim: Obesity is a disease that reduces the quality and duration of life and its prevalence is also increasing in the elderly population.In this study, we aimed to investigate the results of early and midterm weight loss and treatment of concomitant diseases and evaluate the safety and efficacy of bariatric surgery in patients aged 60 years and older who underwent Laparoscopic Sleeve Gastrectomy (LSG) in our clinic. Material and Methods: We retrospectively evaluated 28 morbid obese patients ≥60 years oldwho underwent LSG between September 2014 and January 2018.Data reviewed included age, sex, preoperative weight and body mass index (BMI), comorbid conditions, early or delayed complications, mortality, length of follow-up, weight lost, BMI points lost, and effects on obesity-related comorbid conditions. Results: Of 28 patients included in the study there were 22 (78.6%) females and 6 (21.4%) males. The average age of patients was 63.4±3.39.Preoperative mean BMI was 48.4±7.0kg/m2.Ave...

Research paper thumbnail of The effect of amniotic membrane wrapping on colorectal anastomosis in rats undergoing pelvic radiotherapy

Annals of Medical Research, 2020

Aim: This study aimed to investigate the effect of amniotic membrane wrapped onto the anastomosis... more Aim: This study aimed to investigate the effect of amniotic membrane wrapped onto the anastomosis line following colon resection and primary anastomosis on anastomosis healing in rats undergoing pelvic radiotherapy. Material and Methods: Fifty-six male Wistar albino rats were randomly allocated to four main groups. Group I, left colon resection and primary anastomosis; Group II, post-anastomotic amniotic membrane; Group III, preoperative radiotherapy; Group IV, preoperative radiotherapy and amniotic membrane. Radiotherapy was administered under general anesthesia eight and four days prior to surgery at a total of 20 Gy. In the first operation, all the rats underwent 1 cm left colon resection and primary anastomosis. The animals in each group were anesthetized to assess the clinical, mechanical, histologic, and biochemical parameters of anastomotic healing on the third and seventh postoperative days. Results: In the third day groups, anastomosis line bursting was observed in only one subject in those undergoing amniotic membrane wrapping(p<0.05) and in all rats in those with no amniotic membrane wrapping. No statistically significant difference was observed in any of the parameters on the histopathological examination of the day 3 groups. The amounts of granulation tissue and fibroblast were significantly higher in the post-anastomotic amniotic membrane group (p<0.05), and the macrophage amount was seen to be significantly low in both amniotic membrane groups (p<0.05). Conclusion: Amniotic membrane application on the anastomoses in the intestines, either with or without radiotherapy, may contribute to wound healing by positively affecting the anastomosis health.

Research paper thumbnail of A retrospective comparison of the results of wide excision-lay open, primary closure and flap application in surgical treatment for primary pilonidal sinus disease

Ege Tıp Dergisi, 2019

Amaç: Bu çalışmada primer pilonidal sinüs nedeni ile ameliyat edilen hastalarda geniş eksizyon so... more Amaç: Bu çalışmada primer pilonidal sinüs nedeni ile ameliyat edilen hastalarda geniş eksizyon sonrası açık bırakma (GE), geniş eksizyon primer kapama (PK) ve flep uygulaması (F) yapılan hastaların sonuçlarının karşılaştırılması planlandı. Gereç ve Yöntem: Toplam 249 hastanın verileri retrospektif olarak değerlendirildi. Bu hastaların 12’si nüks hastalık nedeni ile değerlendirme dışı bırakıldı. Hastaların 101’ine GE, 68’ine PK ve 68’ine de F yapılmıştı. Demografik özellikler, semptomların süresi, gluteal kleftin özelliği, perioperatif komplikasyonlar, ameliyat süresi ve hastanede kalış süresi, dren kullanımı ve pansuman durumu patolojik piyes hacmi anüse uzaklık ve hastalığın nüksü kaydedildi. Bulgular: Ortalama operasyon süresi GE grubunda 32,62±9,65; PK grubunda 53,23±15,40; F grubunda 76,69±17,00 dakika idi (p

Research paper thumbnail of Appendiceal intussusception, a peroperative surprise: A case report

Journal of Surgery and Medicine, 2019

Intussusception of the appendix is very uncommon and when encountered, it may alter surgical proc... more Intussusception of the appendix is very uncommon and when encountered, it may alter surgical procedures. For this reason, it should be kept in mind that appendiceal intussusception may occur in every patient diagnosed with acute appendicitis. It is critical to consider appendiceal intussusception in patients presenting with recurrent nausea, vomiting and chronic abdominal pain.

Research paper thumbnail of Comparison of Resection and Liver Transplant in Treatment of Hepatocellular Carcinoma

Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, Jan 28, 2018

Hepatic resection and liver transplant are regarded as 2 potentially curative treatments for hepa... more Hepatic resection and liver transplant are regarded as 2 potentially curative treatments for hepatocellular carcinoma. Here, we compared both options in patients with hepatocellular carcinoma secondary to cirrhosis seen at a single center over 12 years. We evaluated early complications and survival of patients with hepatocellular carcinoma treated with liver transplant (57 patients) or hepatic resection (36 patients) at our center between 1998 and 2010. The 34-month mean follow-up period was similar for both treatment groups. The liver transplant group had a longer hospital stay than the hepatic resection group (P ⟨ .001). Patients with Child-Turcotte-Pugh A stage were treated by hepatic resection more than by liver transplant (P ⟨ .001),with Child-Turcotte-Pugh B stage patients treated by liver transplant more than by hepatic resection (P = .03). All patients with Child-Turcotte-Pugh C stage had liver transplant. Both treatment groups had similar postoperative complications and ear...

Research paper thumbnail of AAsymptomatic cholecysto-enteric fistula and gallstone ileus: Two case reports

Annals of Medical Research, 2018

Research paper thumbnail of Diagnostic Accuracy of Axillary Ultrasound in Early–Stage Breast Cancer

Indian Journal of Surgery, 2018

Sentinel lymph node biopsy is the standard application for evaluating the axilla in patients with... more Sentinel lymph node biopsy is the standard application for evaluating the axilla in patients with breast cancer. The Z0011 trial conducted by The American College of Surgeons Oncology Group (ACOSOG) revealed that axillary dissection may be redundant in selected patients with positive sentinel node. This raises questions regarding the application of this result to ultrasoundpositive patients. This research therefore aimed to evaluate how accurate an ultrasound scan is for axillary node status in earlystage breast carcinoma. The study included 156 newly diagnosed clinical T1-T2, N0 breast cancer patients attending our breast clinic between January 2010 and February 2016. Sentinel lymph node biopsy and axillary lymph node clearance in the presence of sentinel lymph node metastasis was performed on all the breast cancer patients. Axillary ultrasound reports were reviewed retrospectively and the results compared with surgical pathology results. The sensitivity and specificity of axillary ultrasound for detecting axillary lymph node disease was 69.2% and 98%, respectively, with a negative predictive value of 86.4% and positive predictive value of 94.7%. Given the high sensitivity and specificity, and high positive predictive value and negative predictive value demonstrated in the present study, axillary ultrasound represents a potential alternative to sentinel lymph node biopsy for staging of the axilla in early breast cancer. Subsequent trials (SOUND) comparing axillary ultrasound alone with sentinel lymph node biopsy in early breast cancer patients will provide additional information about the subject.

Research paper thumbnail of Changes in serum lipid levels after laparoscopic sleeve gastrectomy in morbidly obese dyslipidemic and normolipidemic patients

Acta chirurgica Belgica, Jan 17, 2017

This study investigated the effect of laparoscopic sleeve gastrectomy (LSG) performed for morbid ... more This study investigated the effect of laparoscopic sleeve gastrectomy (LSG) performed for morbid obesity on serum lipid levels of dyslipidemic and normolipidemic patients. 141 patients who underwent LSG between September 2014 and January 2016 were included in the study. The patients' mean body mass index was 46.27 ± 6.79 kg/mpreoperatively, 31.60 ± 5.37 kg/min the 6th month postoperatively and 27.80 ± 4.25 kg/min the 12th month (p < .001). Preoperatively and 12 months after the operation, mean total cholesterol (TC) levels and mean LDL cholesterol, mean HDL cholesterol, and mean triglyceride (TG) levels were statistically significantly decreased (p < .01). Comparing TC levels in the 12th month with preoperative levels, dyslipidemic patients showed a statistically more significant decrease than normolipidemic patients. LDL cholesterol levels were significantly decreased in both the groups. HDL cholesterol levels increased significantly in both groups while mean TG levels de...

Research paper thumbnail of A case presentation of retrorectal mass approached by multidisciplinary method

Journal of Turkish Association of Colorectal Surgeons, 2011

Research paper thumbnail of Expression and activity levels of matrix metalloproteinase-7 and in situ localization of caseinolytic activity in colorectal cancer

Clinical Biochemistry, 2014

In situ casein zymography Colorectal cancer Objectives: Matrix metalloproteinase-7 is capable of ... more In situ casein zymography Colorectal cancer Objectives: Matrix metalloproteinase-7 is capable of degrading several ECM and non-ECM molecules and contributes to colorectal cancer progression and metastasis. Here, we examined the significance of MMP-7 in colorectal tumors by detecting active and latent MMP-7 levels and localization of its caseinolytic activity. Design and methods: We investigated expression levels, localization, and proteolytic activity of MMP-7 and local caseinolytic activity in colorectal tumor and paired normal tissues by using real time PCR, casein zymography, immunohistochemistry and in situ casein zymography, respectively. In addition the results were compared with clinicopathological variables. Results: Real time PCR and immunohistochemistry showed that MMP-7 expressions were higher in colorectal tumor tissues than in normal tissues. Also, mRNA expressions of MMP-7 were positively correlated with tumor and pathological stages and negatively correlated with age. Furthermore, MMP-7 mRNA expression had a sensitivity of 81.3% and a specificity of 81.2% at a cutoff value of 0.0006, making it a potential marker for diagnosis of colorectal cancer. According to casein zymography, pro-and active MMP-7 levels were also elevated in tumor tissues. In addition, we assessed local caseinolytic activity using in situ casein zymography. Increased immunoreactivity of MMP-7 and local caseinolytic activity were found in neoplastic cells but not in stromal cells. Conclusion: We emphasized the significant role of MMP-7 in diagnosis and progression and/or development of colorectal cancer.

Research paper thumbnail of Five years with a rectal foreign body: A case report

International Journal of Surgery Case Reports, 2015

Research paper thumbnail of Karaciğer Nakli Sonrası İnsizyonel Herni Onarım Sonuçları

Turkiye Klinikleri Journal of Medical Sciences, 2012

Bu olgu serisinde karaciğer nakli sonrası oluşan insizyonel hernilerde risk faktörleri, onarım şe... more Bu olgu serisinde karaciğer nakli sonrası oluşan insizyonel hernilerde risk faktörleri, onarım şekilleri ve sonuçları sunulmaktadır. G Ge er re eç ç v ve e Y Yö ön nt te em ml le er r: : Ortotopik karaciğer nakli yapılan 362 hastanın kayıtları retrospektif olarak incelendi. Bu çalışma tanımlayıcı bir çalışma olarak tasarlandı ve herhangi bir istatistiksel yöntem kullanılmadı. Sonuçlar ortalama±standart sapma ve sayı (%) olarak verildi. Çalışmaya karaciğer nakli sonrası en az bir yıl izlenen hastalar alındı. İlk altı ay içinde ölen 57 (%15,7) hasta çalışma dışı bırakıldı. İnsizyonel herni ortaya çıkan dokuz hastanın risk faktörleri, defekt büyüklükleri, kullanılan yamalar ve onarım şekilleri incelendi. B Bu ul lg gu ul la ar r: : Çalışmaya alınan 305 hastanın dokuzunda (%2,9) insizyonel herni saptandı. Bu hastalarda en sık karaciğer nakil endikasyonu kronik hepatit C'ye bağlı sirozdu. Karaciğer nakli sonrası bu dokuz hastanın dördünde (%44,4) komplikasyon (duodenal ülser perforasyonu, hepatik arter anastomozundan kanama, duodenal ülserden kanama ve mekanik bağırsak tıkanıklığı) gelişti. Dokuz hastanın üçüne relaparotomi uygulandı. Defektin en büyük çapının ortalaması 27,9±10,1 (6-40) cm idi. İnsizyonel herni onarımlarında en sık expanded-politetrafluoroetilen yama kullanıldı. Bir hastada oluşan nüks insizyonel herni dışında erken ve geç dönemde komplikasyon ortaya çıkmadı. S So on nu uç ç: : İnsizyonel herni oluşumu için ek risk faktörlerine sahip sirozlu hastalarda, karaciğer nakli sonrasında uygun kapatılma tekniği ve materyalleri kullanılarak insizyonel herni gelişimi azaltılabilir, insizyonel herni gelişen hastalarda ise uygun yamalar ve teknik kullanılarak güvenle onarım yapılabilir. A An na ah ht ta ar r K Ke el li im me el le er r: : Fıtık, abdominal; karaciğer transplantasyonu; immünosupresyon A AB BS ST TR RA AC CT T O Ob bj je ec ct ti iv ve e: : In this case series, the risk factors, types of repair and outcomes for the development of incisional hernias following liver transplantation are presented. M Ma at te er ri ia al l a an nd d M Me et th ho od ds s: : The medical records of 362 patients who underwent orthotopic liver transplantation were analyzed retrospectively. This study was designed as a descriptive study and statistical methods were not used. Results were given as mean ± standard deviation and number (%). Patients who were followed up for at least one year after liver transplantation were included in the study. Fiftyseven (15.7%) patients who died within the first six months were excluded. The risk factors, defect size, meshes used and types of repair were analyzed in nine patients who developed incisional hernia. R Re es su ul lt ts s: : Incisional hernia was detected in nine (2.9%) out of 305 patients included in the study. The most common indication for liver transplantation was cirrhosis due to chronic viral hepatitis C. Complications (duodenal ulcer perforation, bleeding from hepatic artery anastomosis, bleeding from duodenal ulcer and mechanical intestinal obstruction) developed in four (44.4%) of these nine patients after liver transplantation. Relaparatomy was performed in three of nine patients. The mean largest diameter of defect was 27.9 ± 10.1 (6-40) cm. Expanded-polytetrafluoroethylene mesh was used most frequently for incisional hernia repair. Early or late complications did not develop except one patient who developed recurrent incisional hernia. C Co on nc cl lu us si io on n: : In cirrhotic patients who have additional risk factors for incisional hernia development, the risk of hernia development may be reduced by using appropriate closure technique and materials after liver transplantation. A safe hernia repair may be performed by using an appropriate technique and meshes if the patient develops an incisional hernia.