Bahar ÖÇ - Academia.edu (original) (raw)

Papers by Bahar ÖÇ

The American Journal of Cardiology, 2018

American Journal of Cardiology, 2018

Objective: Carotid artery disease is a major cause of ischemic stroke. Many stenoses are inaccess... more Objective: Carotid artery disease is a major cause of ischemic stroke. Many stenoses are inaccessible surgically and many patients are considered high risk to undergo carotid endarterectomy (CEA). Carotid artery stenting (CS) is an evolving technique for the treatment of carotid artery disease and is the leading alternative to CEA. Diffusion weighted MRI (DWI) offers the possibility of making even small and therefore asymptomatic distal embolic lesions visible. Methods: We prospectively examined 14 patients who underwent CEA and 12 patients who underwent CS from September 2004 to August 2005. DWI was performed on the day before as well as the day after the intervention. Results: Distal embolic lesions were detected at DWI in one patient of CEA group and in one of CS group, which revealed no statistical difference. No post procedural complication was observed. Conclusion: We observed no significant difference regarding post-interventional DWI-lesions. Therefore CEA as well CS are sui...

Arşiv Kaynak Tarama Dergisi, 2014

Foreign body aspiration is a real emergency for chidlren. Mortality and morbidity rates are direc... more Foreign body aspiration is a real emergency for chidlren. Mortality and morbidity rates are directly correlated with clinical symptoms present during admission. The patients may present with a range of symptoms from cardiopulmonary arrest to mild respiratory symptoms without an apparent history of foreign body aspiration. This may lead to delays in diagnosis for several weeks or months which may further worsen lung problems. Chest X-ray or high-resolution computed tomography in the diagnosis phase could be beneficial. Bronchoscopy is used for both confirming the diagnosis and removing the obstruction in airways. Although there is no consensus on which method should be used during these procedures, pharmacological and technical advances in the field of anesthesia has lead to significant decrease in morbidity and mortality. The ventilation and anesthesia methods that would be applied largely depend on the cooperation and compliance between bronchoscopy user and anesthetist. In this article, anesthetic management used to remove foreign bodies in children to remove airway obstructions has been briefly reviewed.

Transplantation Proceedings, 2007

Background. The main metabolic pathway for defluorination of sevoflurane in the liver produces in... more Background. The main metabolic pathway for defluorination of sevoflurane in the liver produces inorganic fluoride (Fl). The metabolism and effect of sevoflurane on the kidney is not clear during anhepatic phase in liver transplantation. The goal of the present study was to investigate the metabolism and renal effect of sevoflurane by measuring plasma and urine inorganic fluoride, urinary N-acetyl-glucosaminidase (NAG), and plasma creatinine levels in patients undergoing liver transplantations. Methods. After institutional approval and informed consent, we studied nine cases of orthotopic liver transplantation after anesthesia was induced with 5 mg • kg Ϫ1 thiopental, 1 g • kg Ϫ1 fentanyl intravenously, the trachea was intubated after vecuronium bromide 0.1 mg • kg Ϫ1. Anesthesia was maintained with sevoflurane (2%), O 2 , and N 2 O at a total gas flow of 6 L • min Ϫ1 using a semiclosed circle system with a sodalime canister. Blood and urine samples were obtained to measure plasma and urine fluoride concentrations and urinary NAG excretions before induction (P0), hourly during resection (P1, P2, P3), every 15 minutes during anhepatic phase (A1, A2, A3), hourly after reperfusion (neohepatic phase) (N1, N2, N3), and postoperative first hour (Po1). Preoperative (T0) and postoperative day 1 (T1), 3 (T3), 7 (T7) plasma blood urea nitrogen (BUN) and creatinine (Cr) levels were also recorded. Results. Mean duration of surgery was 9:06 Ϯ 0:09 hours. Mean inorganic fluoride concentrations in plasma were in the range of 0.71 Ϯ 0.30 to 28.73 Ϯ 3.31 mole • L Ϫ1. In P3, N1, N2, N3, increases in plasma inorganic fluoride concentrations were significant (P Ͻ .05) and reached a peak value at Po1. The mean urine inorganic fluoride concentrations were 12.49 Ϯ 2.04 to 256.7 Ϯ 49.62 mole • L Ϫ1. In A2, A3, N1, N2, and

ajcionline.org

Page 1. Anatol J Clin Investig 2008:2(4):146-149 Birkan Akbulut 100.Yıl Mah. Dumlupınar Bulvarı B... more Page 1. Anatol J Clin Investig 2008:2(4):146-149 Birkan Akbulut 100.Yıl Mah. Dumlupınar Bulvarı Beylikkent Sitesi D-Blok No:5,Kütahya E-mail: birkan.akbulut@gmail.com ERECTILE FUNCTION AFTER CORONARY ARTERY BYPASS SURGERY ...

European Journal of Anaesthesiology, 2004

Renal insufficiency after cardiac surgery is associated with increased mortality, morbidity, and ... more Renal insufficiency after cardiac surgery is associated with increased mortality, morbidity, and length of stay in the intensive care unit. We investigated the effect of isoflurane, halothane, sevoflurane and propofol anesthesia on perioperative renal function following elective coronary artery surgery. The medical records of 224 patients, in the Hacettepe University Medical Faculty Hospital who had undergone cardiac surgery in one year, were retrospectively reviewed. 65 (29%) patients received isoflurane, 68 (30%) patients received halothane, 64 (29%) patients received sevoflurane, and 27 (12%) patients received propofol infusion as part of maintenance anesthesia for coronary artery bypass surgery. Patient characteristics (age, sex, preoperative ejection fraction), operative data (duration of CPB, duration of operation, number of distal anastomoses, usage of diuretic, intraoperative crystalloid and blood transfusion), intraoperative urinary output, preoperative and postoperative (6th hours and 24th hours) BUN and plasma creatinine levels, were not statistically significant between and within groups. Intraoperative inotropic agent (dopamine) was used in 8 (12.3%) patients in the isoflurane group, in 10 (14.7%) patients in the halothane group, in 11 (17.2%) patients in sevoflurane group and in 9 (33.3%) patients in the propofol group. Postoperatively fluid and blood transfusion, postoperative drainage, urinary output, diuretic usage were smiliar between the four groups (p&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;0,05). Inotropic agent was used in 8 (12.3%) patients in the isoflurane group, in 9 (13.2%) patients in the halothane group, in 16 (25%) patients in the sevoflurane group and in 7 (25.9%) patients in the propofol group. It is concluded that, halothane, isoflurane, sevoflurane and propofol infusion anesthesia as part of anesthesia maintenance for elective coronary artery bypass surgery does not affect early postoperative renal functions.

European Journal of Anaesthesiology, 2005

Department of Anaesthesiology and Reanimation, Hacettepe University Faculty of Medicine, Ankara, ... more Department of Anaesthesiology and Reanimation, Hacettepe University Faculty of Medicine, Ankara, Turkey Background and Goal of Study: There are few data on perioperative renal function in cyanotic children (1). We aimed to investigate the perioperative renal function in cyanotic versus acyanotic children undergoing open heart surgery under sevoflurane anaesthesia. Materials and Methods: After receiving ethical committee approval, 12 acyanotic patients (preoperative oxygen saturation: SaO2 85%) and 12 cyanotic children (SaO2 85%) were included. Sevoflurane was given at concentration levels of 2% before cardiopulmonary bypass (CPB) and 1–2% during CPB with BIS monitorization after standard anaesthesia induction. Inorganic fluoride (IF), electrolytes, creatinine (Cr), urea nitrogen in serum and urine samples, N-acetyl-D-glucosaminidase (NAG) in urine samples were measured before induction (t1), before CPB (t2), during CPB (t3), after CPB (t4), at the end of the operation (t5) and 24 hours postoperatively (t6). T-test and chi-square tests were used for statistical analysis. Results and Discussions: The levels of serum uric acid levels were higher in the cyanotic group (p 0.05). While there were no differences in the levels of serum and urine IF between the groups, the levels of serum IF at t2, t3, t4, t5 and the levels of urine IF at t3, t4, t5, t6 were higher compared to t1 in the cyanotic group. No differences were found in the levels of serum and urine Cr, urea nitrogen and electrolytes and NAG levels between the two groups. Data is given as mean SD.

Blood Coagulation & Fibrinolysis, 2011

Nitroglycerin (NTG) reduces the anticoagulant effects of heparin and may lead to heparin resistan... more Nitroglycerin (NTG) reduces the anticoagulant effects of heparin and may lead to heparin resistance. Fresh frozen plasma (FFP) and antithrombin III (ATIII) may be used for the treatment of heparin resistance. We aimed to compare the effects of FFP and ATIII on heparin requirement, coagulation parameters, and bleeding in patients undergoing coronary artery bypass graft surgery (CABGS) with moderate dose of intraoperative NTG infusion. Forty-eight patients undergoing CABGS with NTG infusion were randomly allocated to three groups. Group C served as control, whereas the patients in group P received FFP and those in group A received ATIII after anesthesia induction. ATIII activity and coagulation parameters were measured at five different times intraoperatively. Total heparin requirement, heparin consumption, and heparin sensitivity were calculated. ATIII activity and ACT were significantly higher and activated partial thromboplastin time and fibrinogen level were significantly lower during cardiopulmonary bypass in group A than in groups P and C. Heparin sensitivity was significantly higher and total heparin requirement and consumption were significantly lower in ATIII group than in other groups. ATIII administration increases heparin sensitivity and decreases heparin requirements compared with FFP in patients undergoing CABGS with peroperative NTG infusion. ATIII may be preferred to FFP in patients with heparin resistance due to NTG infusion undergoing CABGS.

Genel Tip Dergisi, Nov 14, 2017