Balasaheb yelikar - Academia.edu (original) (raw)
Papers by Balasaheb yelikar
Journal of Cytology, 2007
... 2 [PUBMED]. 3. Reddy PS, Sadhikhi AK, Rai R. Microfilariae in fine needle aspirates of the li... more ... 2 [PUBMED]. 3. Reddy PS, Sadhikhi AK, Rai R. Microfilariae in fine needle aspirates of the liver [Letter]. Acta Cytol 1998; 42:454. ... 1, Microfilaria in liver aspiration cytology: An extremely rare finding, Mukul Vij, Niraj Kumari, Narendra Krishnani. Diagnostic Cytopathology. 2010; : n/a ...
Indian Journal of Pathology and Microbiology, 2010
Pediatric Dermatology, 2009
A 1-month-old boy was referred to the Pediatric Dermatology Unit with a solitary asymptomatic nod... more A 1-month-old boy was referred to the Pediatric Dermatology Unit with a solitary asymptomatic nodule on the back. The patient was born at 38 weeks gestation after an uncomplicated delivery. The congenital lesion appeared first as a rounded ulceration and started to become exophytic after the second week of life. At the first visit, it presented as a pink well-defined nodule, firm in consistency, with a partially eroded and crusted surface, measuring about 2 · 1.5 cm . Full blood count, serum chemistry, liver function tests, and a complete physical examination were unremarkable.
Pediatric Dermatology, 2005
An 11-year-old girl presented with three nodular lesions on the medial aspect of the right knee t... more An 11-year-old girl presented with three nodular lesions on the medial aspect of the right knee that have been present since early childhood. There was a gradual increase in the size of the lesions, associated with occasional pain. On handling, beads of clear fluid would appear over the lesions . The nodules were closely set, dome-shaped, and about 2.5 × 2.5 cm in size. The overlying skin was smooth and hyperpigmented, with a bluish hue. The consistency of the nodules was firm, associated with tenderness and localized sweating following palpation. The local temperature was normal and no pulsation or bruit was appreciated. A radiograph of the right knee joint was normal.
Sexually Transmitted Infections, 2007
Indian Journal of Dermatology Venereology & Leprology, 2010
Background: Itchy folliculitis are pruritic, folliculo-papular lesions seen in human immunodefici... more Background: Itchy folliculitis are pruritic, folliculo-papular lesions seen in human immunodeficiency virus (HIV)-infected patients. Previous studies have shown that it was impossible to clinically differentiate between eosinophilic folliculitis (EF) and infective folliculitis (IF). Also, attempts to suppress the intense itch of EF were ineffective. Aims: The present study is aimed at correlating clinical, histopathological and immunological features of itchy folliculitis in HIV patients along with their treatment. Methods: The present prospective study lasted for 36 months (September, 2005 to August, 2008) after informed consent, data on skin disorders, HIV status and CD4 count were obtained by physical examination, histopathological examination and laboratory methods. Results: Of 51 HIV-positive patients with itchy folliculitis, the predominant lesion was EF in 23 (45.1%) followed by bacterial folliculitis in 21 (41.2%), Pityrosporum folliculitis in five (9.8%) and Demodex folliculitis in two (3.9%) patients. The diagnosis was based on characteristic histopathological features and was also associated with microbiology confirmation wherever required. EF was associated with a lower mean CD4 count (180.58 ± 48.07 cells/mm 3 , P-value < 0.05), higher mean CD8 count (1675.42 ± 407.62 cells/mm3) and CD8/CD4 ratio of 9.27:1. There was significant reduction in lesions following specific treatment for the specific lesion identified. Conclusion: Clinically, it is impossible to differentiate itchy folliculitis and therefore it requires histopathological confirmation. Appropriate antimicrobial treatment for IF can be rapidly beneficial. The highly active antiretroviral therapy along with Isotretinoin therapy has shown marked reduction in the lesions of EF. Familiarity with these lesions may help in improving the quality of lives of the patients.
Indian Journal of Pathology and Microbiology, 2009
Pruritic papular eruptions (PPE) are common cutaneous manifestations in HIV-infected patients. Th... more Pruritic papular eruptions (PPE) are common cutaneous manifestations in HIV-infected patients. Their frequencies, patterns and associated factors vary from region to region. There is no clear consensus on the etiology of PPE, the exact spectrum of the condition, the pathologic findings, or treatment. The present study is aimed at documenting the histopathological patterns of PPE, and their relation with CD4, CD8 counts in HIV-infected patients. The present study lasted for 12 months (September 2005 to August 2006). After informed consent, data on skin disorders, HIV status, CD4 and CD8 counts were obtained by physical examination and laboratory methods. Of the 36 HIV-infected patients with clinical diagnosis of PPE, the most common histopathological patterns were prurigo simplex and eosinophilic folliculitis. The mean CD4 count of PPE was 186.49 cells/mm3 with mean CD8 count of 619.60 cells/ mm3, and the CD4:CD8 ratio was 0.32. Patients with prurigo simplex had significantly lower mean CD4 counts (50.36 +/- 30.67 cells/cmm 3 , P < 0.001) while in eosinophilic folliculitis, the mean CD8 counts were higher (1239.77 +/- 402.30 cells/cmm3). We conclude that histopathology helps in specifying the pattern of PPE and also indicates underlying immunosuppression and can be a marker of advanced HIV infection. Thus, correlation between the histopathology and immunology findings helps to know the disease process.
Dermatology, 2004
... Occasion-ally, individual nodules ruptured to discharge white granular materi-al. ... Referen... more ... Occasion-ally, individual nodules ruptured to discharge white granular materi-al. ... References 1 Odom RB, James WD, Berger TG: Errors in metabolism; in Odom RB, James WD, Berger TG (eds): Andrew's Diseases of the Skin, Clinical Der-matology, ed 9. Philadelphia ...
Indian Journal of Dermatology Venereology & Leprology, 2008
Journal of Cutaneous Pathology, 2008
A young human immunodeficiency virus-infected man was admitted in unconsciousness state. Few papu... more A young human immunodeficiency virus-infected man was admitted in unconsciousness state. Few papular skin lesions resembling molluscum contagiosum (MC) were present on the face. He was found to have cryptococcal meningitis using India ink preparation of cerebrospinal fluid. Histopathological examination of skin lesion revealed the presence of capsulated yeast forms of Cryptococcus within the lesion of MC. The co-existence of MC and cryptococcosis in the same cutaneous lesion is rare, and it could be because of immunosuppression (low CD4 count).
Pediatric Dermatology, 2004
Postgraduate Medical Journal, 2005
A 52 year old male office worker presented with localised areas of dark, rugose skin over the fac... more A 52 year old male office worker presented with localised areas of dark, rugose skin over the face, dorsa of the hands and feet of 15 days' duration. The lesions were asymptomatic but rapidly progressive causing concern to the patient. In addition, he had weight loss (.10 kg), anorexia, and profound weakness for the past month. He was non-smoker and non-alcoholic. He had been suffering from bleeding piles and anal fissures for the past 15 years. There was no history of fever, cough, respiratory distress, change of bowel habits, or difficulties in micturition.
Indian Journal of Dermatology Venereology & Leprology, 2009
An adult female patient on hemodialysis for chronic renal failure presented with large, brownish,... more An adult female patient on hemodialysis for chronic renal failure presented with large, brownish, and indurated plaques with bound-down skin on both lower limbs and abdomen along with difficulty in movement of the legs. Histopathological features revealed thick collagen bundles admixed with mucin and intercalating spindle-like cells characteristic of nephrogenic fibrosing dermopathy (NFD). Immunohistochemical study showed prominent CD68 positivity and weak CD34 positivity suggesting that the plaques were more than 20-weeks old. NFD in patients with chronic renal failure of unknown cause is a poor prognostic indicator. Early detection before the development of contracture and prompt treatment of NFD and underlying renal failure may reverse this disabling condition.
Pediatric Dermatology, 2004
Journal of Cytology, 2007
... 2 [PUBMED]. 3. Reddy PS, Sadhikhi AK, Rai R. Microfilariae in fine needle aspirates of the li... more ... 2 [PUBMED]. 3. Reddy PS, Sadhikhi AK, Rai R. Microfilariae in fine needle aspirates of the liver [Letter]. Acta Cytol 1998; 42:454. ... 1, Microfilaria in liver aspiration cytology: An extremely rare finding, Mukul Vij, Niraj Kumari, Narendra Krishnani. Diagnostic Cytopathology. 2010; : n/a ...
Indian Journal of Pathology and Microbiology, 2010
Pediatric Dermatology, 2009
A 1-month-old boy was referred to the Pediatric Dermatology Unit with a solitary asymptomatic nod... more A 1-month-old boy was referred to the Pediatric Dermatology Unit with a solitary asymptomatic nodule on the back. The patient was born at 38 weeks gestation after an uncomplicated delivery. The congenital lesion appeared first as a rounded ulceration and started to become exophytic after the second week of life. At the first visit, it presented as a pink well-defined nodule, firm in consistency, with a partially eroded and crusted surface, measuring about 2 · 1.5 cm . Full blood count, serum chemistry, liver function tests, and a complete physical examination were unremarkable.
Pediatric Dermatology, 2005
An 11-year-old girl presented with three nodular lesions on the medial aspect of the right knee t... more An 11-year-old girl presented with three nodular lesions on the medial aspect of the right knee that have been present since early childhood. There was a gradual increase in the size of the lesions, associated with occasional pain. On handling, beads of clear fluid would appear over the lesions . The nodules were closely set, dome-shaped, and about 2.5 × 2.5 cm in size. The overlying skin was smooth and hyperpigmented, with a bluish hue. The consistency of the nodules was firm, associated with tenderness and localized sweating following palpation. The local temperature was normal and no pulsation or bruit was appreciated. A radiograph of the right knee joint was normal.
Sexually Transmitted Infections, 2007
Indian Journal of Dermatology Venereology & Leprology, 2010
Background: Itchy folliculitis are pruritic, folliculo-papular lesions seen in human immunodefici... more Background: Itchy folliculitis are pruritic, folliculo-papular lesions seen in human immunodeficiency virus (HIV)-infected patients. Previous studies have shown that it was impossible to clinically differentiate between eosinophilic folliculitis (EF) and infective folliculitis (IF). Also, attempts to suppress the intense itch of EF were ineffective. Aims: The present study is aimed at correlating clinical, histopathological and immunological features of itchy folliculitis in HIV patients along with their treatment. Methods: The present prospective study lasted for 36 months (September, 2005 to August, 2008) after informed consent, data on skin disorders, HIV status and CD4 count were obtained by physical examination, histopathological examination and laboratory methods. Results: Of 51 HIV-positive patients with itchy folliculitis, the predominant lesion was EF in 23 (45.1%) followed by bacterial folliculitis in 21 (41.2%), Pityrosporum folliculitis in five (9.8%) and Demodex folliculitis in two (3.9%) patients. The diagnosis was based on characteristic histopathological features and was also associated with microbiology confirmation wherever required. EF was associated with a lower mean CD4 count (180.58 ± 48.07 cells/mm 3 , P-value < 0.05), higher mean CD8 count (1675.42 ± 407.62 cells/mm3) and CD8/CD4 ratio of 9.27:1. There was significant reduction in lesions following specific treatment for the specific lesion identified. Conclusion: Clinically, it is impossible to differentiate itchy folliculitis and therefore it requires histopathological confirmation. Appropriate antimicrobial treatment for IF can be rapidly beneficial. The highly active antiretroviral therapy along with Isotretinoin therapy has shown marked reduction in the lesions of EF. Familiarity with these lesions may help in improving the quality of lives of the patients.
Indian Journal of Pathology and Microbiology, 2009
Pruritic papular eruptions (PPE) are common cutaneous manifestations in HIV-infected patients. Th... more Pruritic papular eruptions (PPE) are common cutaneous manifestations in HIV-infected patients. Their frequencies, patterns and associated factors vary from region to region. There is no clear consensus on the etiology of PPE, the exact spectrum of the condition, the pathologic findings, or treatment. The present study is aimed at documenting the histopathological patterns of PPE, and their relation with CD4, CD8 counts in HIV-infected patients. The present study lasted for 12 months (September 2005 to August 2006). After informed consent, data on skin disorders, HIV status, CD4 and CD8 counts were obtained by physical examination and laboratory methods. Of the 36 HIV-infected patients with clinical diagnosis of PPE, the most common histopathological patterns were prurigo simplex and eosinophilic folliculitis. The mean CD4 count of PPE was 186.49 cells/mm3 with mean CD8 count of 619.60 cells/ mm3, and the CD4:CD8 ratio was 0.32. Patients with prurigo simplex had significantly lower mean CD4 counts (50.36 +/- 30.67 cells/cmm 3 , P < 0.001) while in eosinophilic folliculitis, the mean CD8 counts were higher (1239.77 +/- 402.30 cells/cmm3). We conclude that histopathology helps in specifying the pattern of PPE and also indicates underlying immunosuppression and can be a marker of advanced HIV infection. Thus, correlation between the histopathology and immunology findings helps to know the disease process.
Dermatology, 2004
... Occasion-ally, individual nodules ruptured to discharge white granular materi-al. ... Referen... more ... Occasion-ally, individual nodules ruptured to discharge white granular materi-al. ... References 1 Odom RB, James WD, Berger TG: Errors in metabolism; in Odom RB, James WD, Berger TG (eds): Andrew's Diseases of the Skin, Clinical Der-matology, ed 9. Philadelphia ...
Indian Journal of Dermatology Venereology & Leprology, 2008
Journal of Cutaneous Pathology, 2008
A young human immunodeficiency virus-infected man was admitted in unconsciousness state. Few papu... more A young human immunodeficiency virus-infected man was admitted in unconsciousness state. Few papular skin lesions resembling molluscum contagiosum (MC) were present on the face. He was found to have cryptococcal meningitis using India ink preparation of cerebrospinal fluid. Histopathological examination of skin lesion revealed the presence of capsulated yeast forms of Cryptococcus within the lesion of MC. The co-existence of MC and cryptococcosis in the same cutaneous lesion is rare, and it could be because of immunosuppression (low CD4 count).
Pediatric Dermatology, 2004
Postgraduate Medical Journal, 2005
A 52 year old male office worker presented with localised areas of dark, rugose skin over the fac... more A 52 year old male office worker presented with localised areas of dark, rugose skin over the face, dorsa of the hands and feet of 15 days' duration. The lesions were asymptomatic but rapidly progressive causing concern to the patient. In addition, he had weight loss (.10 kg), anorexia, and profound weakness for the past month. He was non-smoker and non-alcoholic. He had been suffering from bleeding piles and anal fissures for the past 15 years. There was no history of fever, cough, respiratory distress, change of bowel habits, or difficulties in micturition.
Indian Journal of Dermatology Venereology & Leprology, 2009
An adult female patient on hemodialysis for chronic renal failure presented with large, brownish,... more An adult female patient on hemodialysis for chronic renal failure presented with large, brownish, and indurated plaques with bound-down skin on both lower limbs and abdomen along with difficulty in movement of the legs. Histopathological features revealed thick collagen bundles admixed with mucin and intercalating spindle-like cells characteristic of nephrogenic fibrosing dermopathy (NFD). Immunohistochemical study showed prominent CD68 positivity and weak CD34 positivity suggesting that the plaques were more than 20-weeks old. NFD in patients with chronic renal failure of unknown cause is a poor prognostic indicator. Early detection before the development of contracture and prompt treatment of NFD and underlying renal failure may reverse this disabling condition.
Pediatric Dermatology, 2004