Bamidele Johnson Alegbeleye - Academia.edu (original) (raw)

Papers by Bamidele Johnson Alegbeleye

Zenodo (CERN European Organization for Nuclear Research), May 21, 2021

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British Journal of Surgery

Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The a... more Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains...

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Worldwide Medicine, 2019

BACKGROUND: Differentiated thyroid cancers with secondaries in sites other than the neck are rela... more BACKGROUND: Differentiated thyroid cancers with secondaries in sites other than the neck are relatively uncommon, and even rarer are the initial atypical presentation i.e. symptoms that are not related to the neck. The objective of this study was to bring to the fore the atypical cases of patients diagnosed with well-differentiated thyroid cancer and the complicating distant metastasis; with specific emphasis on presentation, management and outcome of patients with thyroid malignancy. METHODS: A retrospective cross-sectional descriptive study; in which we conducted a review of casefiles of 126 patients who had thyroid surgeries. There were 48 cases of well-differentiated thyroid cancer with confirmed histopathological diagnosis on the final analysis and we subsequently identified and reviewed 5 patients who initially presented with unusual complaints to the thyroid clinic. RESULTS: During the study period under review, forty-eight consecutive patients, 4 male (8.4%) and 44 females (91.6%) with well-differentiated thyroid cancer, who had more than two follow-up visits to the Thyroid Clinic, over the last two years were included in this study. Subsequently, we described the profile of 5 selected patients with atypical presentations including four patients diagnosed with follicular carcinoma, and one patient with papillary carcinoma. CONCLUSION: It is glaring from this case series that differentiated thyroid cancer can present with atypical manifestations. For the clinicians worldwide, a routine preoperative physical examination of the thyroid patient is mandatory. A high index of clinical suspicion, aggressive work-up and treatment are usually rewarding. We equally suggest and encourage a comprehensive multi-center study for a better understanding of the natural history of the thyroid cancer disease process.

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Paradigm shift may be defined as a fundamental change in the basic concepts and experimental prac... more Paradigm shift may be defined as a fundamental change in the basic concepts and experimental practices of a scientific discipline. Paradigm shift is a concept initially propounded by the American physicist and philosopher Thomas Kuhn in 1964. The populist saying is “the only thing that is constant in nature is change.” 2Gastro-Hépatologie et Nutrition Pédiatriques, CHU Sainte-Justine, Université de Montréal, Montréal (Qc), Canada Globally, there is obviously a “Paradigm Shift” in thesis writing but several teachers, trainers, mentors and academicians in scientific institutions are unaware of the new order of progress in postgraduate research writing. This article therefore is aimed at informing the readers about this paradigm shift. The role of research writing to our society cannot be overemphasized. The creation of a new approach to research writing especially that of PhD by publication has wide range of benefits yet to be mined by our scientific world. This has far reaching impli...

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BACKGROUND: There is a global resolve among Clinicians towards adoption of ima... more BACKGROUND: There is a global resolve among Clinicians towards adoption of imaging modalities in the evaluation of appendicitis because clinical algorithms have been disappointing. We sought to determine the authenticity of interobserver variability in ultrasound scan in a resource-constrained mission hospital settings, northwestern region of Cameroon. METHODS: In this study, we reviewed the standardized diagnostic approach in acute appendicitis and also performed prospective cross observational qualitative testing using sensitivity, specificity, positive predictive value, negative predictive value, and accuracy to determine the interobserver variability of ultrasonography using the medical database of the two Mission Hospitals, northwestern region of Cameroon from January 2012 to December 2016. A sequential non-randomized convenient sampling was used and data was analyzed using the Statistical Package for the Social Sciences version 22. RESULTS: A total of 103 patients who had pre-operative evaluation with Ultrasound scan and subsequently underwent surgery with histo-pathological examination of the removed appendix were analyzed. Their ages ranged from 15 to 65 years with a mean age of 30.6±18. There were 62 males and 41 females with a ratio of 1.5:1. Of the 103 patients, (n=90; 87.4%) cases were diagnosed as AA by histopathology while (n= 9; 8.7%) cases were negative. Ultrasound was positive in (n=75; 72.8%) cases, equivocal in (n=16; 15.5%), and negative in (n=10; 10.4%) cases. Sensitivity of ultrasound from this study when compared with ultrasound as the gold standard was 90.2% with a specificity of 85.6%; while Overall accuracy was 72.4%. Age and gender had no significant relationship with the accuracy of ultrasound in this study (p value=0.2 and 0.7 respectively). CONCLUSION: Ultrasound scan is more useful in detecting than in ruling out appendicitis. The radiological criteria for acute appendicitis, the accuracy of various imaging modalities and the limitations of the availa [...]

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Surgery for pain in the right lower quadrant of the abdomen remains a clinical dilemma. Acute app... more Surgery for pain in the right lower quadrant of the abdomen remains a clinical dilemma. Acute appendicitis is considered one of the commonest surgical emergencies. Correct diagnosis and prompt treatment are required to reduce the development of complications. Ultrasound has been shown to be of value in the diagnosis of acute appendicitis with sensitivity varying from one study to another. Background This retrospective cross-sectional study assessed the accuracy of preoperative ultrasound scan in the evaluation of patients with suspected acute appendicitis. Aim One hundred-and-three adult patients with suspected acute appendicitis who underwent preoperative ultrasound scan of the abdomen and subsequently appendectomy; had the histopathology reports compared with their operative findings. Patients and Methods

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BACKGROUND: The first laparoscopic procedures were performed well for over thirty years in Europe... more BACKGROUND: The first laparoscopic procedures were performed well for over thirty years in Europe. Mostly, these include appendectomy and cholecystectomy. However, in Nigeria and other developing countries, the practice commenced only recently and with encouraging results in many centers. Laparoscopic appendectomy (LA) in the low resource setting remains controversial. We audit the procedures; highlight the cost-saving technique, and the practical skills transfer model for laparoscopic appendectomy performed at Lagoon Hospitals in Lagos, Nigeria. METHODS: We review the hospital records per case of appendectomy done from June 2013 through December 2016 at the Lagoon Hospitals, Lagos Nigeria. RESULTS: Two hundred and fifty-eight 258 patients were diagnosed with acute appendicitis (AA) within the study period. (Number n=97; 37.6%) Patients had open appendectomy (OA). Then (n=16; 6.2%) patients that presented with clinical and radiological diagnosis of complicated AA eventually had an o...

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1* Dr. Bamidele Johnson Alegbeleye, B.Sc, MBBS, MMCS, PhD, FRCS (Glasg.) 2Dr. Rana Khadim Mohamme... more 1* Dr. Bamidele Johnson Alegbeleye, B.Sc, MBBS, MMCS, PhD, FRCS (Glasg.) 2Dr. Rana Khadim Mohammed, B.Sc., M.Sc, PhD 1*Department of Surgery, St Elizabeth Catholic General Hospital & Cardiac Center, Shisong, P.O Box 8, Kumbo-Nso, Northwestern Region, Cameroon 2Department of Biotechnology, College of Science, University of Baghdad, Baghdad, Iraq *Corresponding Author: Email: drbalegbeleye@gmail.com; Tel: +237-670628857*

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Iberoamerican Journal of Medicine, 2020

Introduction: There is the obscurity of published data on surgical management of external abdomin... more Introduction: There is the obscurity of published data on surgical management of external abdominal wall hernias in our environment. This study was, therefore, to describe the pattern, outcome, and experience in the surgical management of anterior abdominal wall hernias in Shisong, Cameroon. Methods: This was a descriptive retrospective study conducted at St. Elizabeth Catholic General Hospital, Shisong. The various cases of abdominal wall hernias performed in the hospital during the study period of three years covering January 2017 to December 2019 by the surgical teams were included. We ensured that Ethical clearance and written informed consent were obtained before the start of the project. Information includes detailed sociodemographic data collected and analyzed by using SPSS 22 statistical software. Results: 465 cases of various abdominal wall hernias were included in this study. The most common type of hernia was indirect inguinal hernia (86.5%), and one rare Spigelian hernia...

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Iberoamerican Journal of Medicine, 2020

Objective: The study aimed to highlight the pattern and treatment outcome of childhood burn injur... more Objective: The study aimed to highlight the pattern and treatment outcome of childhood burn injuries in northwestern Cameroon. Such reports are expected to provide preventive and improvement guidelines in our settings in the long run. Methods: Forty-two consecutive patients under fifteen with burns injuries managed at our facility were prospectively enrolled in the study. Results: The study population was 42 patients, which consisted of 23 (54%) male and 19 (46%) female, with the median 2.40±3.05 years, interquartile range of 1-14 years. The most frequent timing of burns was about mid-day (median 11:50 am). The majority of injuries were right at the patient's homes (70% cases). Interestingly, 4%, 15%, and 20% applied raw-egg, ice, and nothing as the first intervention for their children burns, respectively. Scald burns were the leading category of wounds (p<0.012). The majority of the cases were minor burns injuries with TBSA of 1-12% (p=0.002), with a mortality rate of 4%. C...

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Iberoamerican Journal of Medicine, 2020

Introduction: Public health security is concerned with infection prevention and control worldwide... more Introduction: Public health security is concerned with infection prevention and control worldwide. These measures are the concern of all and sundry to ensure prevention of any outbreaks of diseases that has epidemic potential. Africa may be uniquely positioned to have the most severe and under-detected outcomes related to COVID-19 infection. This article seeks to highlight such challenges of healthcare delivery systems in the context of the COVID-19 pandemic in sub-Saharan Africa. The communique also suggests possible strategies for improvement in such settings. Method: We identified relevant articles to date using a manual library search, journal publications on the subject, and critically reviewed them. Results: We identified and exhaustively discussed the main limitations to public health security in sub-Saharan Africa as follows i) Continuing deterioration of the public health infrastructure for disease control, ii) The changing outlooks of contagious diseases, iii) Private sect...

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Iberoamerican Journal of Medicine, 2020

Objective: This article aims to explore the role and responsibility of physicians in the era of s... more Objective: This article aims to explore the role and responsibility of physicians in the era of social media; the authors take as an example of the current pandemic of Coronavirus disease 2019 (COVID-19). Also, we highlight how social media impact the way populations trust and follow the recommendations of the governments. Methods: We identified relevant articles to date using a manual library search, journal publications on the subject, and critically reviewed them. Results: We critically examined the fake news around COVID-19 disease: the disease origin, manifestations, symptoms, and treatments. The authors also explore the high expectation of people and changes in behaviors that led to risky manners, including self-medication after American President Donald Trump has claimed a major benefit of treatment with chloroquine in COVID-19. Surprisingly, the potential BCG vaccination trials in the COVID-19 pandemic were also greeted with much controversy and rejection, especially in Afri...

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Iberoamerican Journal of Medicine, 2020

Introduction: We report a case of gastroschisis seen in our center, highlighting the rarity of th... more Introduction: We report a case of gastroschisis seen in our center, highlighting the rarity of this clinical entity. The author equally reviewed the existing literature covering the epidemiology, etiopathogenesis, management options, and outcomes of gastroschisis in low-income countries in sub-Saharan Africa and compares the reports with middle-income and high-income countries across the world. Case presentation: A preterm female neonate with a clinical diagnosis of gastroschisis at a primary care center was referred to the Neonatology Service of our tertiary care institution. She received optimal resuscitation and interdisciplinary management. Besides, the baby underwent an initial covering with an improvised silo bag of exposed bowel with unfavorable outcomes. Conclusion: The specific etiological factors for gastroschisis are yet to be established. The condition is considered a multifactorial disease. More frequently than ever, it's becoming easy to make prenatal diagnosis uti...

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Iberoamerican Journal of Medicine, 2020

Introduction: Aspirin has justifiably been called the first miracle drug. In this article, we hig... more Introduction: Aspirin has justifiably been called the first miracle drug. In this article, we highlight the history of Aspirin, a novel mechanism of action, and its use in cardiovascular and other diseases. Also included is a brief statement of emerging new applications. Objective: We highlight principal mechanisms by which Aspirin inhibits acute inflammation and alters platelet-biology; therefore, hypothesized that Aspirin might prove highly beneficial as a novel therapeutic drug for combating severe acute inflammation and thrombosis associated with the cytokine storm in COVID -19 patients. The communiqué also suggests possible strategies for maximizing the gain of Aspirin as a wonder-drug of the future. Discussion: Interestingly, some fascinating studies demonstrated Aspirin's superior benefits with dangerous side effects. Aspirin inhibits COX-1 (cyclooxygenase-1). Its impact on COX-2 is more delicate because it “turns off” COX-2's production of prostaglandins but “switche...

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Journal of Drug Delivery and Therapeutics, 2020

Background: Aspirin is one of the most frequently used and cheapest drugs in medicine. Since its ... more Background: Aspirin is one of the most frequently used and cheapest drugs in medicine. Since its first synthesis in 1897, several medicinal roles and mechanisms of action of Aspirin have become apparent, the latest among these being its role in cancer prevention and treatment. Objective: We present a review of Aspirin's biochemistry and pharmacology, as well as the clinical use of Aspirin. The communiqué also suggests possible strategies for maximizing the gain of Aspirin as a wonder-drug of the future. Methods: The literature search strategy covered printed and online sources, including manual library search (PubMed), Embase, Medline, and Cochrane Library. For papers written in English and published in the last ten years. A systematic analysis of available data was subsequently performed based on the review questions. An estimated 155 articles were found online, and twenty-eight articles utilized in the final analysis. Discussion: Aspirin bel...

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Surgical Research Updates, 2020

BACKGROUND: Enterocutaneous fistula remains an enigma and constitutes one of the most challenging... more BACKGROUND: Enterocutaneous fistula remains an enigma and constitutes one of the most challenging situations to the patient, the caregiver, and the surgeon. Notwithstanding the conglomerates of recent progress in critical care, therapeutics, as well as nutritional support; there is yet attendant high mortality and morbidity. Interestingly, there is the obscurity of the work of literature on the condition in most African settings. Therefore, this article aimed to provide updated data on this critical postoperative complication of abdominal surgery. METHOD: Published articles discussing enterocutaneous fistula up to April 2020 were obtained for review from Medline search, medical libraries, and Google. The google search was done in the English language. Interestingly, the search was conducted using the words “enterocutaneous fistula,” “intestinal fistula,” “bowel fistula,” “enteric fistula,” “fistula surgery,” and “fistula and surgical diseases burden”. Ultimately, sixteen materials were included in the quantitative analysis. Some were excluded from the subgroup analyses. DISCUSSION: Treatment of enterocutaneous fistula remains a surgical challenge despite the recent improvement of supportive patient care. Once enterocutaneous fistula occurs, adequate stabilization of the patient, a thorough investigation of the fistula anatomy, and nonoperative management should initially be attempted. The majority of the uncomplicated enterocutaneous fistula will close spontaneously when adequately managed. Interestingly, a simple suture of the fistula is not recommended. However, to intervene surgically as per uncomplicated fistula requires careful planning, meticulous dissection, resection, and anastomosis or bypass procedures are the preferred surgical procedures; besides, reconstruction of the abdominal wall is critical. A multidisciplinary team approach with a gastroenterologist, interventional radiologists, dieticians, enterostomal therapy nurses, and surgeons will maximize successful enterocutaneous fistula closure.

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Sudan Journal of Medical Sciences, Dec 26, 2019

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International Medicine, 2020

Background: The study sought to test the knowledge and practices of breast self-examination (BSE)... more Background: The study sought to test the knowledge and practices of breast self-examination (BSE) amongst women attending a surgical outpatient clinic in a northwestern region of Cameroon. Based on the information, we aimed to undertake an education intervention program focused on dealing with any knowledge and practice gaps discovered. Methods: A cross-sectional descriptive research design was used. A computer-based random sampling technique was adopted to select 200 female patients attending a surgical outpatient clinic in Shisong, the northwestern region of Cameroon. We obtained our data using pre-tested proforma which composed of four sections: I) Socio-demographic characteristics, II) knowledge about BSE and breast cancer, III) practices of BSE and IV) factors affecting BSE. Data obtained was analyzed using the Statistical Package for the Social Sciences (SPSS) version 22 and presented with inferential descriptive statistics. Results: Results showed that women attending a surgical outpatient clinic showed good knowledge of early warning signs and symptoms about breast cancer as well as BSE. About 36% of the women were confident of the timing to start BSE and 78% were conversant with how BSE is done, but were not competent in their practice. The multivariate analysis showed that the single most significant factor affecting the practice of BSE was forgetfulness, odd-ratio (95% CI)=1.55 (1.32–1.82); p=0.001. Conclusions: The female patients attending a surgical outpatient clinic in Shisong were conversant with BSE and they practiced it. Knowledge and practice of BSE may be improved significantly by encouraging an aggressive primary health awareness campaigns nationwide, training the health care providers and setting-up sustained educational framework as well as policy guidelines on BSE skills.

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Journal of Case Reports and Images, 2019

Background: Bull gore injuries are not common in a city set up but are common in the rural areas.... more Background: Bull gore injuries are not common in a city set up but are common in the rural areas. The range of injuries varies from abdominal, chest, scrotal injuries which are quite different from the usual injuries seen in the emergency and casualty like road traffic injuries and stab injuries. We report a rare case of bull gore injury seen in a 38-year-old farmer, managed in this peripheral mission hospital one involving a stray domestic bull, its management as well as review of the literature. It is aimed that the knowledge gained from analyses of these injuries may be beneficial to other clinicians in general and also applicable to the management of similar injuries sustained in rodeo or agricultural settings. Case Presentation: A 38-year-old male farmer of Kumbo origin, Northwestern Cameroon was seen at the emergency department after being hit by a stray domestic bull in his farm. He presented with a complaint of pain in the left iliac fossa, actively bleeding deep laceration ...

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Open Scientific Journal of Surgery, 2019

Background: The study aims to provide an overview of the spectrum of perforated typhoid fever cas... more Background: The study aims to provide an overview of the spectrum of perforated typhoid fever cases and their outcome that were managed in resource constrained rural mission hospital, Northwestern of Cameroon. Methods: This was a retrospective observational study which was conducted in St Elizabeth Catholic General Hospital, Shisong, Northwestern region of Cameroon over a two year period covering January 2016 and December 2018. The patients included were those admitted and diagnosed of typhoid ileal perforation. Data collected were analyzed using SPSS computer software version 22. Results: During the study period, thirty-eight patients underwent surgery for typhoid ileal perforation. They included 26 (68.43%) males and 12 (31.57%) females with Male to Female ratio of 2.2: 1. Sixty -five percent of cases occurred between the months of July and September. The most common presentations were with abdominal pains (92.11%), and abdominal distention (92.11%). X-ray abdomen revealed pneumo ...

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Zenodo (CERN European Organization for Nuclear Research), May 21, 2021

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British Journal of Surgery

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Worldwide Medicine, 2019

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Iberoamerican Journal of Medicine, 2020

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Iberoamerican Journal of Medicine, 2020

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Iberoamerican Journal of Medicine, 2020

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Iberoamerican Journal of Medicine, 2020

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Iberoamerican Journal of Medicine, 2020

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Iberoamerican Journal of Medicine, 2020

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Journal of Drug Delivery and Therapeutics, 2020

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Surgical Research Updates, 2020

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Sudan Journal of Medical Sciences, Dec 26, 2019

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International Medicine, 2020

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Journal of Case Reports and Images, 2019

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Open Scientific Journal of Surgery, 2019

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