Barbara Bekman - Academia.edu (original) (raw)
Papers by Barbara Bekman
Inżynier i Fizyk Medyczny, 2018
Acta Physica Polonica B, Apr 1, 2003
The 98Mo (16O, xn) reaction has been used to study the level structure of the semi-magic nuclei 1... more The 98Mo (16O, xn) reaction has been used to study the level structure of the semi-magic nuclei 11050Sn, 11150Sn and 11250Sn. The OSIRIS-II array equipped with 10 HPGe detectors with anticompton shields was used in conjunction with an 48-element BGO multiplicity filter. The experiments performed with projectile energy E{16}{O}=60-80 MeV brought results on relative excitation functions, gamma -ray angular distributions,
The e- and e+ energy spectra from the SN1987A Supernova neutrino burst interactions are calculate... more The e- and e+ energy spectra from the SN1987A Supernova neutrino burst interactions are calculated and compared to the observed spectra in Kamiokande-II and IMB experiments. Neutrino oscillations in Supernova and regeneration effects in the Earth, for four combinations of neutrino mass hierarchy (Direct/Inverted) and the value of the mixing angle Theta_13 (Large/Small), are taken into account. The influence of the (anti)neutrino production spectra in Supernova on the observed, in Kamiokande-II and IMB detectors, e-/e+ spectra is shown.
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2004
The European Physical Journal A, 2005
Excited states in 110 Sn and 111 Sn nuclei have been investigated using in-beam γ-ray spectroscop... more Excited states in 110 Sn and 111 Sn nuclei have been investigated using in-beam γ-ray spectroscopic methods. An 16 O beam with an energy of 60-80 MeV was used to bombard a 98 Mo target. On the basis of the relative excitation functions, γ-ray angular distributions, γ-γ and γ-time distributions, γ-ray multiplicity and total energy data, the level schemes of 110 Sn and 111 Sn have been studied and extended up to Eexc ∼ 11.5 MeV, I = 24 , and Eexc ∼ 11.1 MeV and I = (51/2) , respectively. An extension of the intruder, g.s. and negative-parity bands, as well as 5 new band-like structures are proposed in 110 Sn. The nature of newly introduced collective band 8 as well as 10 + states fed in the decay of the collective band is discussed. In the 111 Sn nucleus an intruder band based on the 23/2 − state has been reinvestigated and the extension of the g.s. band and second negative-parity band is given. Evidence for neutron-core coupling in 111 Sn is found. The structure and systematics of excited states in light Sn isotopes is discussed.
arXiv: High Energy Physics - Phenomenology, 2004
Matter effects on neutrino oscillations in both, a supernova and the Earth, change the observed s... more Matter effects on neutrino oscillations in both, a supernova and the Earth, change the observed supernova neutrino spectra. We calculate the expected number of supernova neutrino interactions for ICARUS, SK and SNO detectors as a function of the distance which they traveled in the Earth. Calculations are performed for supernova type II at 10kpc from the Earth, using standard supernova neutrino fluxes described by thermal Fermi--Dirac distributions and the PREM I Earth matter density profile.
Reports of Practical Oncology and Radiotherapy
This article is available in open access under creative common attribution-Non-commercial-No Deri... more This article is available in open access under creative common attribution-Non-commercial-No Derivatives 4.0 International (cc BY-Nc-ND 4.0) license, allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially
Monte Carlo simulations are more and more popular trend in nuclear medicine imaging. They were al... more Monte Carlo simulations are more and more popular trend in nuclear medicine imaging. They were also widely used in radiotherapy and brachytherapy with use of more general simulation software. GATE (Geant4 Application for Tomographic Emission) is a platform developed on general Monte Carlo code designed for simulating and tracking the passage of particles through matter (Geant4) but is specifically designed for nuclear medicine imaging purposes. The aim of this work was to create and validate a model of specific gamma-camera (E.Cam DUET), used in our department, for further use in image analysis and dosimetry field, with GATE simulation platform. We have modeled in first step a point source in the air in three configurations of gamma camera (without collimator, with low-energy high-resolution (LEHR) collimator and with high-energy (HE collimator)), then we have created a phantom with three spherical sources of different sizes but with the same concentration of the radiopharmaceutical...
Polish Journal of Medical Physics and Engineering, 2020
Introduction: One of many procedures to control the quality of radiotherapy is daily imaging of t... more Introduction: One of many procedures to control the quality of radiotherapy is daily imaging of the patient’s anatomy. The CBCT (Cone Beam Computed Tomography) plays an important role in patient positioning, and dose delivery monitoring. Nowadays, CBCT is a baseline for the calculation of fraction and total dose. Thus, it provides the potential for more comprehensive monitoring of the delivered dose and adaptive radiotherapy. However, due to the poor quality and the presence of numerous artifacts, the replacement of the CBCT image with the corrected one is desired for dose calculation. The aim of the study was to validate a method for generating a synthetic CT image based on deformable image registration. Material and methods: A Head & Torso Freepoint phantom, model 002H9K (Computerized Imaging Reference Systems, Norfolk, USA) with inserts was imaged with CT (Computed Tomography). Then, contouring and treatment plan were created in Eclipse (Varian Medical Systems, Palo Alto, CA, USA...
Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology, 2021
Background The comparison between profiles during the commissioning of the treatment planning sys... more Background The comparison between profiles during the commissioning of the treatment planning system is an essential procedure. It is impossible to designate a field size for off-axis, wedged, and FFF beams directly by using the definition of the on-axis symmetric field size. This work proposes the use of different characteristic points as indicators of the field size for commissioning and QA purposes. This work aimed to search for the beam profile's characteristic points and use them for the TPS commissioning purposes. Materials and methods The proposal is to use profile inflection points as the beam profile characteristic points. The usage of dedicated software allowed for comparing distances between inflection points and between points of 50% intensity. For the off-axis, wedged, and FFF fields, comparisons were made to the nominal field sizes. Results Distances between inflection points proved to be different by less than 1 mm from nominal field sizes for all kinds of investi...
Glowne postepy radioterapii w ostatnich latach związane są z wprowadzeniem technik dynamicznych o... more Glowne postepy radioterapii w ostatnich latach związane są z wprowadzeniem technik dynamicznych oraz radioterapii 4D. Radioterapia ruchomych guzow realizowana jest poprzez dwie techniki: bramkowanie ( gating ) i śledzenie ruchow ( tracking ). Ograniczeniem techniki bramkowania jest stosunkowo maly czas fazy oddechowej, w ktorym mozna podac dawke promieniowania, oraz koniecznośc nauczenia pacjenta wlaściwego toru oddechowego. Jednocześnie istnieją sytuacje kliniczne, w ktorych niezbedne staje sie uzycie technik dynamicznych. Modulacja intensywności mocy dawki (IMRT) w polączeniu z obrotem glowicy staly sie podstawą techniki VMAT. Realizacja takiego leczenia zwykle trwa krocej niz w przypadku pozostalych technik dynamicznych, co poza innymi aspektami rowniez wplywa na komfort leczenia pacjenta. Wprowadzony niedawno do uzytkowania przyspieszacz True BeamTM wykorzystuje wszystkie innowacje dotyczące modelowania intensywności mocy dawki oraz bramkowania oddechowego.
Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, has been equipped with ... more Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, has been equipped with a 1.5T MAGNETOM Aera (Siemens Healthcare, Erlangen, Germany) since 2012. An on-site scanner is needed because MRI is used as a standard in both conventional radiotherapy and radiosurgical techniques. According to target volume type and location, various imaging sequences are routinely used. Ionizing radiation has been successfully used for years in the treatment of trigeminal neuralgia. This method enables noninvasive treatment of severe facial pain using a high dose of radiation. With the Leksell Gamma Knife (Elekta AB, Stockholm, Sweden), high dose means 80–90 Gy in a single fraction specified at dose maximum. With the CyberKnife (Accuray, Sunnyvale, CA, USA), it means 60 Gy in a single fraction specified at the isodose encompassing the target volume [1–4]. High radiation doses, very small target volumes and close proximity to critical organs require definition of all the anatomical st...
Journal of Applied Clinical Medical Physics, 2020
The accuracy of radiotherapy is the subject of continuous discussion, and dosimetry methods, part... more The accuracy of radiotherapy is the subject of continuous discussion, and dosimetry methods, particularly in dynamic techniques, are being developed. At the same time, many oncology centers develop quality procedures, including pretreatment and online dose verification and proper patient tracking methods. This work aims to present the possibility of using portal dosimetry in the assessment of radiotherapy repeatability. The analysis was conducted on 74 cases treated with dynamic techniques. Transit dosimetry was made for each collision-free radiation beam. It allowed the comparison of summary fluence maps, obtained for fractions with the corresponding summary maps from all other treatment fractions. For evaluation of the compatibility in the fluence map pairs (6798), the gamma coefficient was calculated. The results were considered in four groups, depending on the used radiotherapy technique: stereotactic fractionated radiotherapy, breath-hold, free-breathing, and conventionally fractionated other cases. The chi 2 or Fisher's exact test was made depending on the size of the analyzed set and also Mann-Whitney U-test was used to compare treatment repeatability of different techniques. The aim was to test whether the null hypothesis of error-free therapy was met. The patient is treated repeatedly if the P-value in all the fluence maps sets is higher than the level of 0.01. The best compatibility between treatment fractions was obtained for the stereotactic technique. The technique with breath-holding gave the lowest percentage of compliance of the analyzed fluence pairs. The results indicate that the repeatability of the treatment is associated with the radiotherapy technique. Treated volume location is also an essential factor found in the evaluation of treatment accuracy. The EPID device is a useful tool in assessing the repeatability of radiotherapy. The proposed method of fluence maps comparison also allows us to assess in which therapeutic session the patient was treated differently from the other fractions.
Nowotwory. Journal of Oncology, 2018
Main advancements in radiation treatment in recent years have included the introduction of dynami... more Main advancements in radiation treatment in recent years have included the introduction of dynamic techniques and 4D radiotherapy. The treatment of movable tumors relies on two important techniques: gating and tracking. The limitation of the former is the relatively short duration of the respiratory phase during which the radiation can be delivered and the need to teach the patient to breathe in accordance with the correct pattern. At the same time, certain clinical situations require the use of dynamic techniques. Intensity modulated radiotherapy (IMRT), combined with gantry rotation, forms the basis for the VMAT technique. The procedure usually takes a shorter time to complete than other dynamic techniques, which considerably improves patient comfort. The recently introduced True Beam TM accelerator employs all the latest innovations in terms of dose-rate modeling and respiratory gating.
Polish Journal of Medical Physics and Engineering, 2019
Biomedical accelerators used in radiotherapy are equipped with detector arrays which are commonly... more Biomedical accelerators used in radiotherapy are equipped with detector arrays which are commonly used to obtain the image of patient position during the treatment session. These devices use both kilovolt and megavolt x-ray beams. The advantage of EPID (Electronic Portal Imaging Device) megavolt panels is the correlation of the measured signal with the calibrated dose. The EPID gives a possibility to verify delivered dose. The aim of the study is to answer the question whether EPID can be useful as a tool for interfraction QC (quality control) of dose and geometry repeatability. The EPID system has been calibrated according to the manufacturer’s recommendations to obtain a signal and dose values correlation. Initially, the uncertainty of the EPID matrix measurement was estimated. According to that, the detecting sensitivity of two parameters was checked: discrepancies between the planned and measured dose and field geometry variance. Moreover, the linearity of measured signal-dose f...
Radiation Oncology, 2018
Background: To appraise the dosimetric features and the quality of the treatment plan for radiosu... more Background: To appraise the dosimetric features and the quality of the treatment plan for radiosurgery of multiple brain metastases optimized with a novel automated engine and to compare with plans optimized for robotic-based delivery. Methods: A set of 15 patients with multiple brain metastases was selected for this in silico study. The technique under investigation is the recently introduced HyperArc. For all patients, three treatment plans were computed and compared: i: a HyperArc; ii: a standard VMAT; iii) a CyberKnife. Dosimetric features were computed for the clinical target volumes as well as for the healthy brain tissue and the organs at risk. Results: The data showed that the best dose homogeneity was achieved with the VMAT technique. HyperArc allowed to minimize the volume of brain receiving 4Gy (as well as for the mean dose and the volume receiving 12Gy, although not statistically significant). The smallest dose on 1 cm 3 volume for all organs at risk is for CK techniques, and the biggest for VMAT (p < 0.05). The Radiation Planning Index coefficient indicates that, there are no significant differences among the techniques investigated, suggesting an equivalence among these. Conclusion: At treatment planning level, the study demonstrates that the use of HyperArc technique can significantly improve the sparing of the healthy brain while maintaining a full coverage of the target volumes.
Inżynier i Fizyk Medyczny, 2018
Acta Physica Polonica B, Apr 1, 2003
The 98Mo (16O, xn) reaction has been used to study the level structure of the semi-magic nuclei 1... more The 98Mo (16O, xn) reaction has been used to study the level structure of the semi-magic nuclei 11050Sn, 11150Sn and 11250Sn. The OSIRIS-II array equipped with 10 HPGe detectors with anticompton shields was used in conjunction with an 48-element BGO multiplicity filter. The experiments performed with projectile energy E{16}{O}=60-80 MeV brought results on relative excitation functions, gamma -ray angular distributions,
The e- and e+ energy spectra from the SN1987A Supernova neutrino burst interactions are calculate... more The e- and e+ energy spectra from the SN1987A Supernova neutrino burst interactions are calculated and compared to the observed spectra in Kamiokande-II and IMB experiments. Neutrino oscillations in Supernova and regeneration effects in the Earth, for four combinations of neutrino mass hierarchy (Direct/Inverted) and the value of the mixing angle Theta_13 (Large/Small), are taken into account. The influence of the (anti)neutrino production spectra in Supernova on the observed, in Kamiokande-II and IMB detectors, e-/e+ spectra is shown.
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2004
The European Physical Journal A, 2005
Excited states in 110 Sn and 111 Sn nuclei have been investigated using in-beam γ-ray spectroscop... more Excited states in 110 Sn and 111 Sn nuclei have been investigated using in-beam γ-ray spectroscopic methods. An 16 O beam with an energy of 60-80 MeV was used to bombard a 98 Mo target. On the basis of the relative excitation functions, γ-ray angular distributions, γ-γ and γ-time distributions, γ-ray multiplicity and total energy data, the level schemes of 110 Sn and 111 Sn have been studied and extended up to Eexc ∼ 11.5 MeV, I = 24 , and Eexc ∼ 11.1 MeV and I = (51/2) , respectively. An extension of the intruder, g.s. and negative-parity bands, as well as 5 new band-like structures are proposed in 110 Sn. The nature of newly introduced collective band 8 as well as 10 + states fed in the decay of the collective band is discussed. In the 111 Sn nucleus an intruder band based on the 23/2 − state has been reinvestigated and the extension of the g.s. band and second negative-parity band is given. Evidence for neutron-core coupling in 111 Sn is found. The structure and systematics of excited states in light Sn isotopes is discussed.
arXiv: High Energy Physics - Phenomenology, 2004
Matter effects on neutrino oscillations in both, a supernova and the Earth, change the observed s... more Matter effects on neutrino oscillations in both, a supernova and the Earth, change the observed supernova neutrino spectra. We calculate the expected number of supernova neutrino interactions for ICARUS, SK and SNO detectors as a function of the distance which they traveled in the Earth. Calculations are performed for supernova type II at 10kpc from the Earth, using standard supernova neutrino fluxes described by thermal Fermi--Dirac distributions and the PREM I Earth matter density profile.
Reports of Practical Oncology and Radiotherapy
This article is available in open access under creative common attribution-Non-commercial-No Deri... more This article is available in open access under creative common attribution-Non-commercial-No Derivatives 4.0 International (cc BY-Nc-ND 4.0) license, allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially
Monte Carlo simulations are more and more popular trend in nuclear medicine imaging. They were al... more Monte Carlo simulations are more and more popular trend in nuclear medicine imaging. They were also widely used in radiotherapy and brachytherapy with use of more general simulation software. GATE (Geant4 Application for Tomographic Emission) is a platform developed on general Monte Carlo code designed for simulating and tracking the passage of particles through matter (Geant4) but is specifically designed for nuclear medicine imaging purposes. The aim of this work was to create and validate a model of specific gamma-camera (E.Cam DUET), used in our department, for further use in image analysis and dosimetry field, with GATE simulation platform. We have modeled in first step a point source in the air in three configurations of gamma camera (without collimator, with low-energy high-resolution (LEHR) collimator and with high-energy (HE collimator)), then we have created a phantom with three spherical sources of different sizes but with the same concentration of the radiopharmaceutical...
Polish Journal of Medical Physics and Engineering, 2020
Introduction: One of many procedures to control the quality of radiotherapy is daily imaging of t... more Introduction: One of many procedures to control the quality of radiotherapy is daily imaging of the patient’s anatomy. The CBCT (Cone Beam Computed Tomography) plays an important role in patient positioning, and dose delivery monitoring. Nowadays, CBCT is a baseline for the calculation of fraction and total dose. Thus, it provides the potential for more comprehensive monitoring of the delivered dose and adaptive radiotherapy. However, due to the poor quality and the presence of numerous artifacts, the replacement of the CBCT image with the corrected one is desired for dose calculation. The aim of the study was to validate a method for generating a synthetic CT image based on deformable image registration. Material and methods: A Head & Torso Freepoint phantom, model 002H9K (Computerized Imaging Reference Systems, Norfolk, USA) with inserts was imaged with CT (Computed Tomography). Then, contouring and treatment plan were created in Eclipse (Varian Medical Systems, Palo Alto, CA, USA...
Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology, 2021
Background The comparison between profiles during the commissioning of the treatment planning sys... more Background The comparison between profiles during the commissioning of the treatment planning system is an essential procedure. It is impossible to designate a field size for off-axis, wedged, and FFF beams directly by using the definition of the on-axis symmetric field size. This work proposes the use of different characteristic points as indicators of the field size for commissioning and QA purposes. This work aimed to search for the beam profile's characteristic points and use them for the TPS commissioning purposes. Materials and methods The proposal is to use profile inflection points as the beam profile characteristic points. The usage of dedicated software allowed for comparing distances between inflection points and between points of 50% intensity. For the off-axis, wedged, and FFF fields, comparisons were made to the nominal field sizes. Results Distances between inflection points proved to be different by less than 1 mm from nominal field sizes for all kinds of investi...
Glowne postepy radioterapii w ostatnich latach związane są z wprowadzeniem technik dynamicznych o... more Glowne postepy radioterapii w ostatnich latach związane są z wprowadzeniem technik dynamicznych oraz radioterapii 4D. Radioterapia ruchomych guzow realizowana jest poprzez dwie techniki: bramkowanie ( gating ) i śledzenie ruchow ( tracking ). Ograniczeniem techniki bramkowania jest stosunkowo maly czas fazy oddechowej, w ktorym mozna podac dawke promieniowania, oraz koniecznośc nauczenia pacjenta wlaściwego toru oddechowego. Jednocześnie istnieją sytuacje kliniczne, w ktorych niezbedne staje sie uzycie technik dynamicznych. Modulacja intensywności mocy dawki (IMRT) w polączeniu z obrotem glowicy staly sie podstawą techniki VMAT. Realizacja takiego leczenia zwykle trwa krocej niz w przypadku pozostalych technik dynamicznych, co poza innymi aspektami rowniez wplywa na komfort leczenia pacjenta. Wprowadzony niedawno do uzytkowania przyspieszacz True BeamTM wykorzystuje wszystkie innowacje dotyczące modelowania intensywności mocy dawki oraz bramkowania oddechowego.
Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, has been equipped with ... more Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, has been equipped with a 1.5T MAGNETOM Aera (Siemens Healthcare, Erlangen, Germany) since 2012. An on-site scanner is needed because MRI is used as a standard in both conventional radiotherapy and radiosurgical techniques. According to target volume type and location, various imaging sequences are routinely used. Ionizing radiation has been successfully used for years in the treatment of trigeminal neuralgia. This method enables noninvasive treatment of severe facial pain using a high dose of radiation. With the Leksell Gamma Knife (Elekta AB, Stockholm, Sweden), high dose means 80–90 Gy in a single fraction specified at dose maximum. With the CyberKnife (Accuray, Sunnyvale, CA, USA), it means 60 Gy in a single fraction specified at the isodose encompassing the target volume [1–4]. High radiation doses, very small target volumes and close proximity to critical organs require definition of all the anatomical st...
Journal of Applied Clinical Medical Physics, 2020
The accuracy of radiotherapy is the subject of continuous discussion, and dosimetry methods, part... more The accuracy of radiotherapy is the subject of continuous discussion, and dosimetry methods, particularly in dynamic techniques, are being developed. At the same time, many oncology centers develop quality procedures, including pretreatment and online dose verification and proper patient tracking methods. This work aims to present the possibility of using portal dosimetry in the assessment of radiotherapy repeatability. The analysis was conducted on 74 cases treated with dynamic techniques. Transit dosimetry was made for each collision-free radiation beam. It allowed the comparison of summary fluence maps, obtained for fractions with the corresponding summary maps from all other treatment fractions. For evaluation of the compatibility in the fluence map pairs (6798), the gamma coefficient was calculated. The results were considered in four groups, depending on the used radiotherapy technique: stereotactic fractionated radiotherapy, breath-hold, free-breathing, and conventionally fractionated other cases. The chi 2 or Fisher's exact test was made depending on the size of the analyzed set and also Mann-Whitney U-test was used to compare treatment repeatability of different techniques. The aim was to test whether the null hypothesis of error-free therapy was met. The patient is treated repeatedly if the P-value in all the fluence maps sets is higher than the level of 0.01. The best compatibility between treatment fractions was obtained for the stereotactic technique. The technique with breath-holding gave the lowest percentage of compliance of the analyzed fluence pairs. The results indicate that the repeatability of the treatment is associated with the radiotherapy technique. Treated volume location is also an essential factor found in the evaluation of treatment accuracy. The EPID device is a useful tool in assessing the repeatability of radiotherapy. The proposed method of fluence maps comparison also allows us to assess in which therapeutic session the patient was treated differently from the other fractions.
Nowotwory. Journal of Oncology, 2018
Main advancements in radiation treatment in recent years have included the introduction of dynami... more Main advancements in radiation treatment in recent years have included the introduction of dynamic techniques and 4D radiotherapy. The treatment of movable tumors relies on two important techniques: gating and tracking. The limitation of the former is the relatively short duration of the respiratory phase during which the radiation can be delivered and the need to teach the patient to breathe in accordance with the correct pattern. At the same time, certain clinical situations require the use of dynamic techniques. Intensity modulated radiotherapy (IMRT), combined with gantry rotation, forms the basis for the VMAT technique. The procedure usually takes a shorter time to complete than other dynamic techniques, which considerably improves patient comfort. The recently introduced True Beam TM accelerator employs all the latest innovations in terms of dose-rate modeling and respiratory gating.
Polish Journal of Medical Physics and Engineering, 2019
Biomedical accelerators used in radiotherapy are equipped with detector arrays which are commonly... more Biomedical accelerators used in radiotherapy are equipped with detector arrays which are commonly used to obtain the image of patient position during the treatment session. These devices use both kilovolt and megavolt x-ray beams. The advantage of EPID (Electronic Portal Imaging Device) megavolt panels is the correlation of the measured signal with the calibrated dose. The EPID gives a possibility to verify delivered dose. The aim of the study is to answer the question whether EPID can be useful as a tool for interfraction QC (quality control) of dose and geometry repeatability. The EPID system has been calibrated according to the manufacturer’s recommendations to obtain a signal and dose values correlation. Initially, the uncertainty of the EPID matrix measurement was estimated. According to that, the detecting sensitivity of two parameters was checked: discrepancies between the planned and measured dose and field geometry variance. Moreover, the linearity of measured signal-dose f...
Radiation Oncology, 2018
Background: To appraise the dosimetric features and the quality of the treatment plan for radiosu... more Background: To appraise the dosimetric features and the quality of the treatment plan for radiosurgery of multiple brain metastases optimized with a novel automated engine and to compare with plans optimized for robotic-based delivery. Methods: A set of 15 patients with multiple brain metastases was selected for this in silico study. The technique under investigation is the recently introduced HyperArc. For all patients, three treatment plans were computed and compared: i: a HyperArc; ii: a standard VMAT; iii) a CyberKnife. Dosimetric features were computed for the clinical target volumes as well as for the healthy brain tissue and the organs at risk. Results: The data showed that the best dose homogeneity was achieved with the VMAT technique. HyperArc allowed to minimize the volume of brain receiving 4Gy (as well as for the mean dose and the volume receiving 12Gy, although not statistically significant). The smallest dose on 1 cm 3 volume for all organs at risk is for CK techniques, and the biggest for VMAT (p < 0.05). The Radiation Planning Index coefficient indicates that, there are no significant differences among the techniques investigated, suggesting an equivalence among these. Conclusion: At treatment planning level, the study demonstrates that the use of HyperArc technique can significantly improve the sparing of the healthy brain while maintaining a full coverage of the target volumes.