Barry Mishra - Academia.edu (original) (raw)

Papers by Barry Mishra

Research paper thumbnail of A framework for enterprise risk identification and management: the resource-based view

Managerial Auditing Journal, 2019

Purpose This study aims to examine the factors influencing enterprise risk management and propose... more Purpose This study aims to examine the factors influencing enterprise risk management and propose a framework for identifying and explaining the components of enterprise risk management. To enable broader analytical thinking about risk factors, the framework utilizes the resource-based theory to link various classes of risks to an extended set of organizational resources. Design/methodology/approach The paper opted for an exploratory study using a sample from an online survey. The survey subjects were recruited from the membership database of the American Institute of Certified Public Accountants, focusing primarily on CFOs. The survey consisted of six sections: demographics, a section on each of the four risk types included in ERM: strategic risk, operational risk, financial risk and hazard risk, and exit questions (where very general questions about ERM were asked). The survey yielded a data set of 227 valid responses. Findings Using the associated sample survey data, the paper pr...

Research paper thumbnail of Indigenous <i>Lactobacillus</i> strains improve growth performance and high density cholesterol levels in broilers

556-563Antibiotics have been used extensively in poultry chicken to promote growth rate, increase... more 556-563Antibiotics have been used extensively in poultry chicken to promote growth rate, increase feed conversion efficiency, and prevent intestinal infections, resulting in an imbalance of the beneficial intestinal flora. The use of lactic acid bacteria as feed additives to substitute antibiotic associated growth stimulators as well as their impact on meat quality, could possibly be the major approach. In this context, here, we studied two Lactobacillus cultures viz., L. plantarum KGL3A and L. fermentum KGL4 as an alternative to growth promoters. Broilers were grouped into four different treatments: T1 (control: basal diet + antibiotic growth promoter and immunomodulatory factor), T2 [basal diet without having antibiotic growth promoter and immunomodulatory factor + L. plantarum KGL3A (108 CFU/mL)], T3 [basal diet without having antibiotic growth promoter and immunomodulatory factor + L. fermentum KGL4 (108 CFU/mL)] and T4 (basal diet without having antibiotic growth promoter and i...

Research paper thumbnail of Expression of extracellular matrix metalloproteinase inducer (EMMPRIN) and its related extracellular matrix degrading enzymes in the endometrium during estrous cycle and early gestation in cattle

Reproductive Biology and Endocrinology, 2010

Research paper thumbnail of Dietary supplementation of alpha-lipoic acid mitigates the negative effects of heat stress in broilers

PLoS ONE, 2021

Heat stress accounts for substantial economic loss in the poultry industry by altering the health... more Heat stress accounts for substantial economic loss in the poultry industry by altering the health and performance of chickens. Alpha-lipoic acid (ALA) is a water and fat-soluble antioxidant which is readily absorbed from the intestine resulting in maximum bioavailability. Moreover, ALA acts as a coenzyme in glucose metabolism and helps generate other antioxidants. Considering these benefits, we hypothesized that dietary supplementation of ALA would help mitigate heat stress in poultry. A total of 72 Day-old broiler chicks were randomly assigned into three treatment groups: no heat stress (NHS), heat stress with basal diet (HS), and heat stress with alpha-lipoic acid (HS+ALA); each treatment group had 6 replicate pens with 4 birds in each pen (n = 24/group). The allocated birds were raised under standard husbandry practices for 3 weeks. After 21 d, birds in the HS and HS+ALA groups were exposed to heat stress (33°C for 8 hours during the day) for 3 weeks, while the NHS group was rear...

Research paper thumbnail of Effects of Multi-Enzymes on Growth Performance , and Effects of Multi-Enzymes and Probiotics on Nutrient Utilization in Broilers Fed Different Level of Fibers

Research paper thumbnail of Effect of Nutritional Factors on Growth Behaviour, Proteolytic, β-Glucosidase and β-Galactosidase Activities of Lactobacillus Cultures during Soy-Drink Fermentation

Current Research in Nutrition and Food Science Journal, 2020

In this study, inulin, whey protein concentrate (WPC 70) and skimmed milk powder (SMP) were used ... more In this study, inulin, whey protein concentrate (WPC 70) and skimmed milk powder (SMP) were used as nutritional factors to improve the quality of soy-drink fermented with indigenous Lactobacillus cultures. The growth behaviour (pH, titratable acidity, viable cell count), β-glucosidase, β-galactosidase, and proteolytic activity of indigenous Lactobacillus cultures were studied with various nutritional supplements in soy-drink. Two-way analysis of variance (ANOVA) was applied and the post-hoc comparison was acquired by Tukey’s HSD test for all the data presented in the study. Due to the supplementation of nutritional factors, the pH dropped as a bit of lactic acid production was also observed due to a lack of lactose. The supplements also provided extra nutrition during their growth in different incubation hours. At 2% rate of WPC 70 supplementation, maximum proteolysis (1.17 O.D.) was found by L. fermentum K7. L. fermentum K16 showed the highest β-glucosidase enzyme activity (0.154µM...

Research paper thumbnail of Impact of Lactobacillus cultures on production of B-vitamins, organic acids and biotransformation of soy isoflavones

Acta Alimentaria, 2021

In the study, four potent Lactobacillus cultures of L. rhamnosus K4E, L. plantarum RD7, L. fermen... more In the study, four potent Lactobacillus cultures of L. rhamnosus K4E, L. plantarum RD7, L. fermentum K7, and L. fermentum K16 were considered for the production of B-vitamins, organic acids and biotransformation of soy isoflavones. L. plantarum RD7 showed the highest B2 production (0.84 μg mL−1) after 36 h, while L. fermentum K16 exhibited maximum B12 production (0.084 μg mL−1) after 12 h. L. rhamnosus K4E produced 0.24 μg mL−1 of folate after 12 h. Highest production of lactate (16.43 μg mL−1) and acetate (5.86 μg mL−1) was reported by L. rhamnosus K4E. L. plantarum RD7 showed maximum butyrate (0.253 μg mL−1) production compared to the other cultures. The highest bioconversion of soy aglycones was reported by L. rhamnosus K4E with 55.43% for daidzein and 72.30% for genistein, during soymilk fermentation. These potent cultures have a potential to be used as functional starter cultures for the production of functional fermented soy foods.

Research paper thumbnail of Effects of supplemental xylanase and xylooligosaccharides on production performance and gut health variables of broiler chickens

Journal of Animal Science and Biotechnology, 2021

Background This study evaluated the effects of supplemental xylanase and xylooligosaccharides (XO... more Background This study evaluated the effects of supplemental xylanase and xylooligosaccharides (XOS) in a corn-soybean meal (SBM)-based diet on growth performance and intestinal health of broilers. A total of 288 day-old chicks (Cobb 500) were allocated to 36 floor pens (8 birds/pen) equally in 9 dietary treatments in a 3 × 3 factorial arrangement. The treatments were combinations of 3 levels of xylanase (0, 0.005% and 0.01% Econase XT) and 3 levels of prebiotics (0, 0.005% and 0.01% XOS) added to basal mash diets formulated in three phases (starter, d 0–14; grower, d 15–28; finisher, d 29–42). The feed intake and body weights were recorded weekly. On d 42, ileal sections were collected for histomorphometric and gene expression analysis, and cecal content was collected for determining short-chain fatty acids (SCFA) and microbiota. Results Xylanase linearly (P 0.05). Supplemental xylanase and XOS did not affect average daily feed intake and feed conversion ratio (P > 0.05). Xylana...

Research paper thumbnail of Dietary supplementation of dried plum: a novel strategy to mitigate heat stress in broiler chickens

Journal of Animal Science and Biotechnology, 2021

Background Heat stress is a significant problem in the poultry industry, causing a severe economi... more Background Heat stress is a significant problem in the poultry industry, causing a severe economic loss due to its detrimental effects on chickens’ health and performance. Dried plum (DP) is a good source of minerals, vitamins, antioxidants, and phenolic compounds. Studies have suggested that DP has several health benefits, such as maintaining the body’s redox system, immune status, and calcium hemostasis. Based on the health benefits of DP, we hypothesized that the dietary supplementation of DP would alleviate the detrimental effects of heat stress on broiler chickens. Results To test the hypothesis, day-old broiler chicks (n = 72) were randomly allocated to three treatment groups (n = 24/group): no heat stress (NHS), heat stress (HS), and heat stress with dried plum (HS + DP), and reared under standard conditions. The inclusion of 2.5% DP in the feed of the HS + DP group was made during the treatment period, while birds in other groups were provided with a standard finisher diet. ...

Research paper thumbnail of Impact of Heat Stress on Poultry Health and Performances, and Potential Mitigation Strategies

Animals, 2020

Heat stress is one of the major environmental stressors in the poultry industry resulting in subs... more Heat stress is one of the major environmental stressors in the poultry industry resulting in substantial economic loss. Heat stress causes several physiological changes, such as oxidative stress, acid-base imbalance, and suppressed immunocompetence, which leads to increased mortality and reduced feed efficiency, body weight, feed intake, and egg production, and also affects meat and egg quality. Several strategies, with a variable degree of effectiveness, have been implemented to attenuate heat stress in poultry. Nutritional strategies, such as restricting the feed, wet or dual feeding, adding fat in diets, supplementing vitamins, minerals, osmolytes, and phytochemicals, have been widely studied and found to reduce the deleterious effects of heat stress. Furthermore, the use of naked neck (Na) and frizzle (F) genes in certain breed lines have also gained massive attention in recent times. However, only a few of these strategies have been widely used in the poultry industry. Therefor...

Research paper thumbnail of Transcriptional Profiling Shows that BHR4 and E74A Are the Regulators of CPH33 and CPH34 Gene Expression

Journal of Advances in Molecular Biology, 2018

Research paper thumbnail of Successively expressed cuticular protein genes at the prepupal stage in wing discs of Bombyx mori

The Journal of Basic and Applied Zoology, 2019

Background We classified cuticular protein genes expressed at prepupal stage in wing discs of Bom... more Background We classified cuticular protein genes expressed at prepupal stage in wing discs of Bombyx mori into six groups according to their developmental expression and ecdysone responsiveness. Their expression pattern is suggested to be regulated by ecdysone-responsive transcription factors, whose transcripts showed resemblance with those of cuticular protein gene expression. Result Group1 and Group2 CP genes showed peak expression at stage W2. Group3 CP genes showed high expression at stage W3E and W3L and were upregulated by 20E addition, showing a peak 12 h after 20E pulse treatment. Group4 CP gene transcripts started expression from stage V5 and peaked at stage W3L. Some genes showed significant increase 4 or 6 h after 20E addition and were induced 6 h and showed a peak 18 h after the 20E pulse treatment. Group5 CP gene transcripts peaked at the same stage W3L. Some Group5 genes showed significant increase 6 h after the 20E addition, while others were not induced by the 20E ad...

Research paper thumbnail of Author Correction: Reproductive hazards of space travel in women and men

Nature Reviews Endocrinology, 2019

Research paper thumbnail of Early Nutrition Programming (in ovo and Post-hatch Feeding) as a Strategy to Modulate Gut Health of Poultry

Frontiers in Veterinary Science, 2019

Research paper thumbnail of Genetic and Hormonal Regulation of Egg Formation in the Oviduct of Laying Hens

Poultry [Working Title], 2019

Research paper thumbnail of Synergistic inhibition of csal1 and csal3 in granulosa cell proliferation and steroidogenesis of hen ovarian prehierarchical development

Biology of Reproduction, 2019

Spalt-like 1 (SALL1) and spalt-like 3 (SALL3) are multi-zinc finger transcription factors that pl... more Spalt-like 1 (SALL1) and spalt-like 3 (SALL3) are multi-zinc finger transcription factors that play an essential role in regulating developmental processes and organogenesis in many species. However, the functional role of SALL1 (csal1) and SALL3 (csal3) in chicken prehierarchical follicle (PF) development is unknown. This study aimed to explore the potential role and mechanism of csal1 and csal3 in granulosa cells (GCs) proliferation, differentiation, and follicle selection within the PFs of hen ovary. Our data demonstrated that the csal1 and csal3 transcriptions were highly expressed in GCs of the various-sized PFs and their proteins were mainly localized in the cytoplasm of granulosa cells and oocytes of the examined PFs as well as in the ovarian stroma and epithelium. It initially revealed that both csal1 and csal3 may be involved in chicken PF development via a translocation mechanism. Furthermore, our results showed an abundance of CCND1, Bcat, StAR, CYP11A1, and FSHR mRNA in ...

Research paper thumbnail of Bio-nutritional aspects of Tungrymbai, an ethnic functional fermented soy food of Khasi Hills, Meghalaya, India

Clinical Nutrition Experimental, 2019

Research paper thumbnail of Oxidative Stress in the Poultry Gut: Potential Challenges and Interventions

Frontiers in Veterinary Science, 2019

Research paper thumbnail of Very low doses of heavy oxygen ion radiation induce premature ovarian failure

Reproduction (Cambridge, England), Aug 20, 2017

Astronauts are exposed to charged particles during space travel, and charged particles are also u... more Astronauts are exposed to charged particles during space travel, and charged particles are also used for cancer radiotherapy. Premature ovarian failure is a well-known side-effect of conventional, low linear energy transfer (LET) cancer radiotherapy, but little is known about the effects of high LET charged particles on the ovary. We hypothesized that lower LET (16.5 keV/µm) oxygen particles would be less damaging to the ovary than we previously found for iron (LET=179 keV/µm). Adult female mice were irradiated with 0, 5, 30, or 50 cGy oxygen ions or 50 cGy oxygen plus dietary supplementation with the antioxidant alpha lipoic acid (ALA). 6h after irradiation, percentages of ovarian follicles immunopositive for γH2AX, a marker of DNA double strand breaks, 4-HNE, a marker of oxidative lipid damage, and PUMA, a proapoptotic BCL-2 family protein, were dose-dependently increased in irradiated mice compared to controls. One week after irradiation, numbers of primordial, primary, and secon...

Research paper thumbnail of Budget Adjustments and Spending Patterns: A Transaction Cycle View

Journal of Information Systems, 2017

Organizational- and departmental-level budgeting suffer from various shortcomings, such as asymme... more Organizational- and departmental-level budgeting suffer from various shortcomings, such as asymmetric ratcheting. In this regard, we theorize, and propose, budgeting at the transaction-cycle level for effective budget designs. The transaction-cycle level budget requires management justification for resource assignment to business processes, often spanning multiple departments. The transaction-cycle typology consists of five cycles: production, expenditure, financial, revenue, and human-resources. In order to distinguish among transaction cycles, we use their relative positions within the value chain and technology content in their business processes. As a proof-of-concept, we develop theoretical arguments for asymmetric ratcheting in operating budgets at the transaction-cycle level in hospitals, and empirically examine this phenomenon using longitudinal archival data. Our hypotheses examine budgetary responses to overspending and underspending variances in operating budgets for fixe...

Research paper thumbnail of A framework for enterprise risk identification and management: the resource-based view

Managerial Auditing Journal, 2019

Purpose This study aims to examine the factors influencing enterprise risk management and propose... more Purpose This study aims to examine the factors influencing enterprise risk management and propose a framework for identifying and explaining the components of enterprise risk management. To enable broader analytical thinking about risk factors, the framework utilizes the resource-based theory to link various classes of risks to an extended set of organizational resources. Design/methodology/approach The paper opted for an exploratory study using a sample from an online survey. The survey subjects were recruited from the membership database of the American Institute of Certified Public Accountants, focusing primarily on CFOs. The survey consisted of six sections: demographics, a section on each of the four risk types included in ERM: strategic risk, operational risk, financial risk and hazard risk, and exit questions (where very general questions about ERM were asked). The survey yielded a data set of 227 valid responses. Findings Using the associated sample survey data, the paper pr...

Research paper thumbnail of Indigenous <i>Lactobacillus</i> strains improve growth performance and high density cholesterol levels in broilers

556-563Antibiotics have been used extensively in poultry chicken to promote growth rate, increase... more 556-563Antibiotics have been used extensively in poultry chicken to promote growth rate, increase feed conversion efficiency, and prevent intestinal infections, resulting in an imbalance of the beneficial intestinal flora. The use of lactic acid bacteria as feed additives to substitute antibiotic associated growth stimulators as well as their impact on meat quality, could possibly be the major approach. In this context, here, we studied two Lactobacillus cultures viz., L. plantarum KGL3A and L. fermentum KGL4 as an alternative to growth promoters. Broilers were grouped into four different treatments: T1 (control: basal diet + antibiotic growth promoter and immunomodulatory factor), T2 [basal diet without having antibiotic growth promoter and immunomodulatory factor + L. plantarum KGL3A (108 CFU/mL)], T3 [basal diet without having antibiotic growth promoter and immunomodulatory factor + L. fermentum KGL4 (108 CFU/mL)] and T4 (basal diet without having antibiotic growth promoter and i...

Research paper thumbnail of Expression of extracellular matrix metalloproteinase inducer (EMMPRIN) and its related extracellular matrix degrading enzymes in the endometrium during estrous cycle and early gestation in cattle

Reproductive Biology and Endocrinology, 2010

Research paper thumbnail of Dietary supplementation of alpha-lipoic acid mitigates the negative effects of heat stress in broilers

PLoS ONE, 2021

Heat stress accounts for substantial economic loss in the poultry industry by altering the health... more Heat stress accounts for substantial economic loss in the poultry industry by altering the health and performance of chickens. Alpha-lipoic acid (ALA) is a water and fat-soluble antioxidant which is readily absorbed from the intestine resulting in maximum bioavailability. Moreover, ALA acts as a coenzyme in glucose metabolism and helps generate other antioxidants. Considering these benefits, we hypothesized that dietary supplementation of ALA would help mitigate heat stress in poultry. A total of 72 Day-old broiler chicks were randomly assigned into three treatment groups: no heat stress (NHS), heat stress with basal diet (HS), and heat stress with alpha-lipoic acid (HS+ALA); each treatment group had 6 replicate pens with 4 birds in each pen (n = 24/group). The allocated birds were raised under standard husbandry practices for 3 weeks. After 21 d, birds in the HS and HS+ALA groups were exposed to heat stress (33°C for 8 hours during the day) for 3 weeks, while the NHS group was rear...

Research paper thumbnail of Effects of Multi-Enzymes on Growth Performance , and Effects of Multi-Enzymes and Probiotics on Nutrient Utilization in Broilers Fed Different Level of Fibers

Research paper thumbnail of Effect of Nutritional Factors on Growth Behaviour, Proteolytic, β-Glucosidase and β-Galactosidase Activities of Lactobacillus Cultures during Soy-Drink Fermentation

Current Research in Nutrition and Food Science Journal, 2020

In this study, inulin, whey protein concentrate (WPC 70) and skimmed milk powder (SMP) were used ... more In this study, inulin, whey protein concentrate (WPC 70) and skimmed milk powder (SMP) were used as nutritional factors to improve the quality of soy-drink fermented with indigenous Lactobacillus cultures. The growth behaviour (pH, titratable acidity, viable cell count), β-glucosidase, β-galactosidase, and proteolytic activity of indigenous Lactobacillus cultures were studied with various nutritional supplements in soy-drink. Two-way analysis of variance (ANOVA) was applied and the post-hoc comparison was acquired by Tukey’s HSD test for all the data presented in the study. Due to the supplementation of nutritional factors, the pH dropped as a bit of lactic acid production was also observed due to a lack of lactose. The supplements also provided extra nutrition during their growth in different incubation hours. At 2% rate of WPC 70 supplementation, maximum proteolysis (1.17 O.D.) was found by L. fermentum K7. L. fermentum K16 showed the highest β-glucosidase enzyme activity (0.154µM...

Research paper thumbnail of Impact of Lactobacillus cultures on production of B-vitamins, organic acids and biotransformation of soy isoflavones

Acta Alimentaria, 2021

In the study, four potent Lactobacillus cultures of L. rhamnosus K4E, L. plantarum RD7, L. fermen... more In the study, four potent Lactobacillus cultures of L. rhamnosus K4E, L. plantarum RD7, L. fermentum K7, and L. fermentum K16 were considered for the production of B-vitamins, organic acids and biotransformation of soy isoflavones. L. plantarum RD7 showed the highest B2 production (0.84 μg mL−1) after 36 h, while L. fermentum K16 exhibited maximum B12 production (0.084 μg mL−1) after 12 h. L. rhamnosus K4E produced 0.24 μg mL−1 of folate after 12 h. Highest production of lactate (16.43 μg mL−1) and acetate (5.86 μg mL−1) was reported by L. rhamnosus K4E. L. plantarum RD7 showed maximum butyrate (0.253 μg mL−1) production compared to the other cultures. The highest bioconversion of soy aglycones was reported by L. rhamnosus K4E with 55.43% for daidzein and 72.30% for genistein, during soymilk fermentation. These potent cultures have a potential to be used as functional starter cultures for the production of functional fermented soy foods.

Research paper thumbnail of Effects of supplemental xylanase and xylooligosaccharides on production performance and gut health variables of broiler chickens

Journal of Animal Science and Biotechnology, 2021

Background This study evaluated the effects of supplemental xylanase and xylooligosaccharides (XO... more Background This study evaluated the effects of supplemental xylanase and xylooligosaccharides (XOS) in a corn-soybean meal (SBM)-based diet on growth performance and intestinal health of broilers. A total of 288 day-old chicks (Cobb 500) were allocated to 36 floor pens (8 birds/pen) equally in 9 dietary treatments in a 3 × 3 factorial arrangement. The treatments were combinations of 3 levels of xylanase (0, 0.005% and 0.01% Econase XT) and 3 levels of prebiotics (0, 0.005% and 0.01% XOS) added to basal mash diets formulated in three phases (starter, d 0–14; grower, d 15–28; finisher, d 29–42). The feed intake and body weights were recorded weekly. On d 42, ileal sections were collected for histomorphometric and gene expression analysis, and cecal content was collected for determining short-chain fatty acids (SCFA) and microbiota. Results Xylanase linearly (P 0.05). Supplemental xylanase and XOS did not affect average daily feed intake and feed conversion ratio (P > 0.05). Xylana...

Research paper thumbnail of Dietary supplementation of dried plum: a novel strategy to mitigate heat stress in broiler chickens

Journal of Animal Science and Biotechnology, 2021

Background Heat stress is a significant problem in the poultry industry, causing a severe economi... more Background Heat stress is a significant problem in the poultry industry, causing a severe economic loss due to its detrimental effects on chickens’ health and performance. Dried plum (DP) is a good source of minerals, vitamins, antioxidants, and phenolic compounds. Studies have suggested that DP has several health benefits, such as maintaining the body’s redox system, immune status, and calcium hemostasis. Based on the health benefits of DP, we hypothesized that the dietary supplementation of DP would alleviate the detrimental effects of heat stress on broiler chickens. Results To test the hypothesis, day-old broiler chicks (n = 72) were randomly allocated to three treatment groups (n = 24/group): no heat stress (NHS), heat stress (HS), and heat stress with dried plum (HS + DP), and reared under standard conditions. The inclusion of 2.5% DP in the feed of the HS + DP group was made during the treatment period, while birds in other groups were provided with a standard finisher diet. ...

Research paper thumbnail of Impact of Heat Stress on Poultry Health and Performances, and Potential Mitigation Strategies

Animals, 2020

Heat stress is one of the major environmental stressors in the poultry industry resulting in subs... more Heat stress is one of the major environmental stressors in the poultry industry resulting in substantial economic loss. Heat stress causes several physiological changes, such as oxidative stress, acid-base imbalance, and suppressed immunocompetence, which leads to increased mortality and reduced feed efficiency, body weight, feed intake, and egg production, and also affects meat and egg quality. Several strategies, with a variable degree of effectiveness, have been implemented to attenuate heat stress in poultry. Nutritional strategies, such as restricting the feed, wet or dual feeding, adding fat in diets, supplementing vitamins, minerals, osmolytes, and phytochemicals, have been widely studied and found to reduce the deleterious effects of heat stress. Furthermore, the use of naked neck (Na) and frizzle (F) genes in certain breed lines have also gained massive attention in recent times. However, only a few of these strategies have been widely used in the poultry industry. Therefor...

Research paper thumbnail of Transcriptional Profiling Shows that BHR4 and E74A Are the Regulators of CPH33 and CPH34 Gene Expression

Journal of Advances in Molecular Biology, 2018

Research paper thumbnail of Successively expressed cuticular protein genes at the prepupal stage in wing discs of Bombyx mori

The Journal of Basic and Applied Zoology, 2019

Background We classified cuticular protein genes expressed at prepupal stage in wing discs of Bom... more Background We classified cuticular protein genes expressed at prepupal stage in wing discs of Bombyx mori into six groups according to their developmental expression and ecdysone responsiveness. Their expression pattern is suggested to be regulated by ecdysone-responsive transcription factors, whose transcripts showed resemblance with those of cuticular protein gene expression. Result Group1 and Group2 CP genes showed peak expression at stage W2. Group3 CP genes showed high expression at stage W3E and W3L and were upregulated by 20E addition, showing a peak 12 h after 20E pulse treatment. Group4 CP gene transcripts started expression from stage V5 and peaked at stage W3L. Some genes showed significant increase 4 or 6 h after 20E addition and were induced 6 h and showed a peak 18 h after the 20E pulse treatment. Group5 CP gene transcripts peaked at the same stage W3L. Some Group5 genes showed significant increase 6 h after the 20E addition, while others were not induced by the 20E ad...

Research paper thumbnail of Author Correction: Reproductive hazards of space travel in women and men

Nature Reviews Endocrinology, 2019

Research paper thumbnail of Early Nutrition Programming (in ovo and Post-hatch Feeding) as a Strategy to Modulate Gut Health of Poultry

Frontiers in Veterinary Science, 2019

Research paper thumbnail of Genetic and Hormonal Regulation of Egg Formation in the Oviduct of Laying Hens

Poultry [Working Title], 2019

Research paper thumbnail of Synergistic inhibition of csal1 and csal3 in granulosa cell proliferation and steroidogenesis of hen ovarian prehierarchical development

Biology of Reproduction, 2019

Spalt-like 1 (SALL1) and spalt-like 3 (SALL3) are multi-zinc finger transcription factors that pl... more Spalt-like 1 (SALL1) and spalt-like 3 (SALL3) are multi-zinc finger transcription factors that play an essential role in regulating developmental processes and organogenesis in many species. However, the functional role of SALL1 (csal1) and SALL3 (csal3) in chicken prehierarchical follicle (PF) development is unknown. This study aimed to explore the potential role and mechanism of csal1 and csal3 in granulosa cells (GCs) proliferation, differentiation, and follicle selection within the PFs of hen ovary. Our data demonstrated that the csal1 and csal3 transcriptions were highly expressed in GCs of the various-sized PFs and their proteins were mainly localized in the cytoplasm of granulosa cells and oocytes of the examined PFs as well as in the ovarian stroma and epithelium. It initially revealed that both csal1 and csal3 may be involved in chicken PF development via a translocation mechanism. Furthermore, our results showed an abundance of CCND1, Bcat, StAR, CYP11A1, and FSHR mRNA in ...

Research paper thumbnail of Bio-nutritional aspects of Tungrymbai, an ethnic functional fermented soy food of Khasi Hills, Meghalaya, India

Clinical Nutrition Experimental, 2019

Research paper thumbnail of Oxidative Stress in the Poultry Gut: Potential Challenges and Interventions

Frontiers in Veterinary Science, 2019

Research paper thumbnail of Very low doses of heavy oxygen ion radiation induce premature ovarian failure

Reproduction (Cambridge, England), Aug 20, 2017

Astronauts are exposed to charged particles during space travel, and charged particles are also u... more Astronauts are exposed to charged particles during space travel, and charged particles are also used for cancer radiotherapy. Premature ovarian failure is a well-known side-effect of conventional, low linear energy transfer (LET) cancer radiotherapy, but little is known about the effects of high LET charged particles on the ovary. We hypothesized that lower LET (16.5 keV/µm) oxygen particles would be less damaging to the ovary than we previously found for iron (LET=179 keV/µm). Adult female mice were irradiated with 0, 5, 30, or 50 cGy oxygen ions or 50 cGy oxygen plus dietary supplementation with the antioxidant alpha lipoic acid (ALA). 6h after irradiation, percentages of ovarian follicles immunopositive for γH2AX, a marker of DNA double strand breaks, 4-HNE, a marker of oxidative lipid damage, and PUMA, a proapoptotic BCL-2 family protein, were dose-dependently increased in irradiated mice compared to controls. One week after irradiation, numbers of primordial, primary, and secon...

Research paper thumbnail of Budget Adjustments and Spending Patterns: A Transaction Cycle View

Journal of Information Systems, 2017

Organizational- and departmental-level budgeting suffer from various shortcomings, such as asymme... more Organizational- and departmental-level budgeting suffer from various shortcomings, such as asymmetric ratcheting. In this regard, we theorize, and propose, budgeting at the transaction-cycle level for effective budget designs. The transaction-cycle level budget requires management justification for resource assignment to business processes, often spanning multiple departments. The transaction-cycle typology consists of five cycles: production, expenditure, financial, revenue, and human-resources. In order to distinguish among transaction cycles, we use their relative positions within the value chain and technology content in their business processes. As a proof-of-concept, we develop theoretical arguments for asymmetric ratcheting in operating budgets at the transaction-cycle level in hospitals, and empirically examine this phenomenon using longitudinal archival data. Our hypotheses examine budgetary responses to overspending and underspending variances in operating budgets for fixe...