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Papers by Bello Samuel
International Journal of Innovative Science and Research Technology, 2020
The benefit of food as medicine is that healing and health promotion begins as soon as the next m... more The benefit of food as medicine is that healing and health promotion begins as soon as the next meal and this is known some decades ago as the significance of diet in health improvement, and prevention of diseases came to vanguard. Type 2 (non-insulin dependent) diabetes mellitus is a complex, multi-faceted disease particularized by high blood glucose (hyperglycemia), insulin resistance, pancreatic beta-cell dysfunction and altered insulin secretion. Recent data indicates a disturbing increase in the rate of hitches among individuals having type 2 diabetes mellitus despite the availability of several pharmacological involvements such as oral hypoglycemic agents and insulin therapy for its control. As a response to this, functional foods for example whole grains, cinnamon, legumes, nuts were developed, which are now vital substitutes for enhancing nutrition and public health. Therefore, investigation into the advantages of functional foods on type 2 diabetes mellitus is essential and...
GSC Biological and Pharmaceutical Sciences, 2020
GSC Biological and Pharmaceutical Sciences
Neurodegenerative diseases are age related decline in the functionality of neurons and nerve cell... more Neurodegenerative diseases are age related decline in the functionality of neurons and nerve cells hampering healthy ageing and associated with features such as learning shortfall, memory mishap, subjective decay and long term dementia. Biochemical underlying hallmarks include oxidative stress as a result of ROS generation and mitochondrial dysfunction, cholinesterase malfunction and inflammation of neurons. Neurodegenerative diseases represent a major threat to ageing population, as it is projected that in 2050, one in eighty-five individuals would have Alzheimer’s disease. In this review, various functional foods were elucidated to possess bioactive compounds that exhibit neuroprotective activities via their: antioxidant, anti-amyloid aggregation, modification of monoamines and acetylcholinesterase inhibition amongst others. Lately, illuminating directions are towards frugal functional foods and bioactive compounds that would help the global populace as medicinal foods in the prevention, treatment and management of neurodegenerative diseases. This review attempts to evaluate the various functional foods, their bioactive compounds, their possible mechanism of action in the attempt to ensure healthy ageing, novel drug development and frugal neurodegenerative diseases management. Keywords: Neurodegenerative diseases; Functional foods; Bioactive compounds; Alzheimer’s disease; Parkinson’s disease; Mechanism of action.
International Journal of Innovative Science and Research Technology, 2020
The benefit of food as medicine is that healing and health promotion begins as soon as the next m... more The benefit of food as medicine is that healing and health promotion begins as soon as the next meal and this is known some decades ago as the significance of diet in health improvement, and prevention of diseases came to vanguard. Type 2 (non-insulin dependent) diabetes mellitus is a complex, multi-faceted disease particularized by high blood glucose (hyperglycemia), insulin resistance, pancreatic beta-cell dysfunction and altered insulin secretion. Recent data indicates a disturbing increase in the rate of hitches among individuals having type 2 diabetes mellitus despite the availability of several pharmacological involvements such as oral hypoglycemic agents and insulin therapy for its control. As a response to this, functional foods for example whole grains, cinnamon, legumes, nuts were developed, which are now vital substitutes for enhancing nutrition and public health. Therefore, investigation into the advantages of functional foods on type 2 diabetes mellitus is essential and...
GSC Biological and Pharmaceutical Sciences, 2020
GSC Biological and Pharmaceutical Sciences
Neurodegenerative diseases are age related decline in the functionality of neurons and nerve cell... more Neurodegenerative diseases are age related decline in the functionality of neurons and nerve cells hampering healthy ageing and associated with features such as learning shortfall, memory mishap, subjective decay and long term dementia. Biochemical underlying hallmarks include oxidative stress as a result of ROS generation and mitochondrial dysfunction, cholinesterase malfunction and inflammation of neurons. Neurodegenerative diseases represent a major threat to ageing population, as it is projected that in 2050, one in eighty-five individuals would have Alzheimer’s disease. In this review, various functional foods were elucidated to possess bioactive compounds that exhibit neuroprotective activities via their: antioxidant, anti-amyloid aggregation, modification of monoamines and acetylcholinesterase inhibition amongst others. Lately, illuminating directions are towards frugal functional foods and bioactive compounds that would help the global populace as medicinal foods in the prevention, treatment and management of neurodegenerative diseases. This review attempts to evaluate the various functional foods, their bioactive compounds, their possible mechanism of action in the attempt to ensure healthy ageing, novel drug development and frugal neurodegenerative diseases management. Keywords: Neurodegenerative diseases; Functional foods; Bioactive compounds; Alzheimer’s disease; Parkinson’s disease; Mechanism of action.