Benjamín Turner - Academia.edu (original) (raw)

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Papers by Benjamín Turner

Maps showing the location of the study site, its topography, and locations of each experimental p... more Maps showing the location of the study site, its topography, and locations of each experimental plot.

ANOVA tables for the factorial, incomplete block design for the eight response variables analyzed... more ANOVA tables for the factorial, incomplete block design for the eight response variables analyzed in this article.

File List Data.txt Description The data.txt file is a tab-delimited ascii file. It contains all r... more File List Data.txt Description The data.txt file is a tab-delimited ascii file. It contains all response variables presented in this article. The first row contains the capitalized variable names used in column definitions below. Column definitions: 1. PLOT – An integer to identify the 32 experimental plots 2. N – A value of 1 (one) identifies an N addition plot. A value of 0 (zero) identifies a plot that did not receive added N. 3. P – A value of 1 (one) identifies a P addition plot. A value of 0 (zero) identifies a plot that did not receive added P. 4. K – A value of 1 (one) identifies a K addition plot. A value of 0 (zero) identifies a plot that did not receive added K. 5. BLOCK – An integer to identify the two blocks within each replicate. In the balanced, incomplete blocks design, one block in each replicate includes the treatments +N, +P, +K and +NPK and the second block in each replicate includes the treatments CONTROL, +NP, +NK and +PK. Values are 0 (zero) or 1 (one). 6. REP...

Associated files for analyses

Detailed model description and results.

Detailed nutrient data for the 12 study species and soil map of the study site.

Nitrogen-to-phosphorus (N:P) ratios in newly mature leaves, old leaves, stems, and roots for each... more Nitrogen-to-phosphorus (N:P) ratios in newly mature leaves, old leaves, stems, and roots for each of the fertilizer treatments.

$Research paper thumbnail of Appendix A. A species list with life-form, total composited litter, number of traps in which litter was found, and the axis 1 score from the PCA of soluble fraction$

A species list with life-form, total composited litter, number of traps in which litter was found... more A species list with life-form, total composited litter, number of traps in which litter was found, and the axis 1 score from the PCA of soluble fraction.

File List supplemental_litter_leaching_20120822.csv (md5: a5b18924aff40de97816e3a41342150a) Descr... more File List supplemental_litter_leaching_20120822.csv (md5: a5b18924aff40de97816e3a41342150a) Description The file contains initial litter quality and water soluble element data listed by species. Initial litter quality data was determined by grinding and homogenizing 10 g of litter (petioles removed) per species. Water soluble element and pH data show the average of three water extracts per species, with the exception of inorganic N that only had two replicates per species. Water soluble element and pH data are from 4 h extracts. All data expressed on a litter mass basis use oven-dried (60°C) mass. Columns are as follows: 1. Species. Species are referenced by species code. See Appendix A for species names. 2. Total Al concentration in the initial litter expressed as mg Al/g litter. 3. Total C concentration in the initial litter expressed as mg C/g litter. 4. Total Ca concentration in the initial litter expressed as mg Ca/g litter. 5. Total K concentration in the initial litter expres...

Supplementary site and species information including Pearson correlation tables and principal com... more Supplementary site and species information including Pearson correlation tables and principal component analyses of environmental variables and seedling traits.

Seedling survival curves for each species at each site in protected and unprotected gardens.

Data from: Lai, H.R., J.S. Hall, S.A. Batterman, B.L. Turner & M. van ... more Data from: Lai, H.R., J.S. Hall, S.A. Batterman, B.L. Turner & M. van Breugel (2018). Nitrogen fixer abundance has no effect on biomass recovery during tropical secondary forest succession. Journal of Ecology Methods and materials;See 'Methods & Materials' section in Lai et al. 2018 for details Summary:1) Nitrogen-fixing trees (N2 fixers) provide new nitrogen critical for rapid biomass accumulation of tropical forests during early secondary succession, but it remains unclear how the abundance of N2 fixers in the forest community affects the growth of non-fixers or the primary productivity of the whole forest. 2) On the one hand, N2 fixers may enhance forest productivity by providing a facilitative effect through the provision of plant-available nitrogen to non-fixing trees. On the other hand, N2 fixers may suppress the growth of non-fixers by growing faster and competing more vigorously for light and other resources. A third alternative is that the growth of N2 fixers themselves accumulate biomass rapidly, while having a neutral effect on non-fixers, leading to an overall increase in forest biomass.3) We examine these alternative hypotheses using five-year tree census data from 88 plots in 44 seasonal tropical moist secondary forests (3–32 years old) across a human-modified landscape in central Panama. We examined whether N2 fixers accumulated biomass more rapidly than non-fixers, and how relative biomass of N2 fixers as a functional group and as individual species influenced the growth of non-fixer and whole stand primary productivity.4) Surprisingly, we found no evidence for either a net competitive or a facilitative effect of N2 fixers as a functional group or individual species on the biomass recovery in these young forests. N2 fixers did not grow faster than non-fixers. Individual mortality rates were lower among N2 fixers, but biomass losses due to mortality were similar between the two groups. Overall, we found no relationship between the relative abundance of N2 fixers [...]

Supplementary results: seedling performance in relation to the main environmental gradient among ... more Supplementary results: seedling performance in relation to the main environmental gradient among the sites and to a multivariate seedling trait axis.

Raw data used in this study (.xlsx file). Different data types are enclosed in different tabs in ... more Raw data used in this study (.xlsx file). Different data types are enclosed in different tabs in the worksheet.

mBio, 2020

Phosphorus (P) is an essential nutrient that is often in limited supply, with P availability cons... more Phosphorus (P) is an essential nutrient that is often in limited supply, with P availability constraining biomass production in many terrestrial ecosystems. Despite decades of work on plant responses to P deficiency and the importance of soil microbes to terrestrial ecosystem processes, how soil microbes respond to, and cope with, P deficiencies remains poorly understood. We studied 583 soils from two independent sample sets that each span broad natural gradients in extractable soil P and collectively represent diverse biomes, including tropical forests, temperate grasslands, and arid shrublands.

Journal of Ecology, 2019

Edaphic factors and initial conditions can regulate the speed of forest succession. Edaphic facto... more Edaphic factors and initial conditions can regulate the speed of forest succession. Edaphic factors, which include soil chemistry and topography, determine soil resource availability and can filter species as forests mature. Initial plant cover early in succession can determine the rates at which secondary forests change in structure, richness, biomass and composition over time. While some of the effects of edaphic factors and initial conditions on forest succession have been studied, how they simultaneously modify young regenerating tropical forest has rarely been examined. We surveyed 22 young forests plots in Panama for 7 years (11, 6 and 3‐year‐old stands when censuses began). We study how tree and liana species composition change early in succession, as well as how edaphic factors (soil nutrients and topography) and initial conditions (initial basal area and forest canopy cover) influence changes in tree and liana abundance, species richness, biomass and composition throughout ...

Cancer Cell, 2019

Ripretinib (DCC-2618) was designed to inhibit the full spectrum of mutant KIT and PDGFRA kinases ... more Ripretinib (DCC-2618) was designed to inhibit the full spectrum of mutant KIT and PDGFRA kinases found in cancers and myeloproliferative neoplasms, particularly in gastrointestinal stromal tumors (GISTs), in which the heterogeneity of drug-resistant KIT mutations is a major challenge. Ripretinib is a ''switch-control'' kinase inhibitor that forces the activation loop (or activation ''switch'') into an inactive conformation. Ripretinib inhibits all tested KIT and PDGFRA mutants, and notably is a type II kinase inhibitor demonstrated to broadly inhibit activation loop mutations in KIT and PDGFRA, previously thought only achievable with type I inhibitors. Ripretinib shows efficacy in preclinical cancer models, and preliminary clinical data provide proof-of-concept that ripretinib inhibits a wide range of KIT mutants in patients with drug-resistant GISTs.

Cancer Research, 2018

The IDO pathway mediates immunosuppressive effects by metabolizing tryptophan (Trp) into kynureni... more The IDO pathway mediates immunosuppressive effects by metabolizing tryptophan (Trp) into kynurenine (Kyn). The depletion of Trp stimulates downstream signaling through nutrient sensors GCN2 and mTOR, while the production of Kyn stimulates signaling through the aryl-hydrocarbon receptor (AHR) transcription factor. The activation of these signaling pathways has pleiotropic effects on immune cells, including influencing the differentiation of dendritic cells (DCs), helper T cells, and regulatory T cells (Treg) as well as enhancing the proliferation of effector T cells and Treg. Indoximod has been demonstrated to relieve IDO-mediated immunosuppression in vitro and in vivo, by creating an artificial Trp-sufficiency signal that bypasses activation of GCN2 and inhibition of mTOR in conditions of Trp deprivation. We hypothesized that indoximod's activity could also include the disruption of AHR activation by Kyn and other Trp catabolites, causing differential AHR signaling and transcrip...