Bernard Fanthome - Academia.edu (original) (raw)
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Papers by Bernard Fanthome
Journal of Ayurveda and Integrative Medicine, 2019
Background: Urolithiasis is a growing problem worldwide. Many a times, asymptomatic stones are ke... more Background: Urolithiasis is a growing problem worldwide. Many a times, asymptomatic stones are kept under observation. Many herbal preparations are available for the same, but they lack proper scientific documentation. Objective: To study the anti-urolithiatic effect of an herbal preparation, Subap Plus (IP) capsules in patients with asymptomatic renal calculi of size ranging from 4 to 9 mm. Material and methods: This was a prospective, randomized, double-blind, placebo-controlled clinical trial conducted in a tertiary care hospital in Pune, India. Patients with asymptomatic renal calculi of 4e9 mm size were randomized (1:1, block randomization) to one of the group Subap Plus (treatment group) or placebo (placebo group). The study outcome included change in visual analog scale (VAS), change in the surface area and density of calculi and their expulsion. Statistical analysis was performed using student's t-test and Chi-square test. Results: A total of 120 patients were screened and 84 were enrolled who met the eligibility criteria, of which 65 patients completed the trial (treatment, n ¼ 34; placebo, n ¼ 31). The VAS score significantly decreased in the treatment group (6.9e1.8) than placebo group (7.2e6.8) (p < 0.001). The surface area and density were decreased by 47.58% (p < 0.008) and 43.01% (p < 0.001), respectively, in the treatment group than the placebo group. The expulsion of calculi was significantly higher in the treatment group than placebo group (20.59 vs. 3.23%, p < 0.03). Conclusion: Patients treated with herbal formulation showed better expulsion rate and reduction in surface area and density than the placebo group.
Journal of Ayurveda and Integrative Medicine
Indian Journal of Pathology and Microbiology
006495 Malik A;Borole A;Fanthome B;Veniyoor A;Misra R N INHS Asvini, Western Naval Command Hospit... more 006495 Malik A;Borole A;Fanthome B;Veniyoor A;Misra R N INHS Asvini, Western Naval Command Hospital, Mumbai , Prognostic correlation of tumor growth fraction and hormonal receptor status in breast carcinoma , 2007,50(1),142
Journal of Cancer Research and Therapeutics, 2012
Follicular dendritic cell sarcoma (FDCS) is a spindle cell neoplasm of histiocytic-dendritic cell... more Follicular dendritic cell sarcoma (FDCS) is a spindle cell neoplasm of histiocytic-dendritic cells origin. It is known to occur in lymph nodes and rarely has been reported in extranodal tissues like head and neck, mediastinum and gastrointestinal tract. We herein report the first FDCS arising from anal canal in a 56-year-old man. The tumor was composed of bland short spindle cells in focal whorl formation with interspersed few lymphocytes. The tumor cells were classically positive for CD21, CD23, CD35 and vimentin. Despite its misleading morphology, immunohistochemistry helped us to reach a conclusive diagnosis for relevant therapy.
Journal of Ayurveda and Integrative Medicine, 2019
Background: Urolithiasis is a growing problem worldwide. Many a times, asymptomatic stones are ke... more Background: Urolithiasis is a growing problem worldwide. Many a times, asymptomatic stones are kept under observation. Many herbal preparations are available for the same, but they lack proper scientific documentation. Objective: To study the anti-urolithiatic effect of an herbal preparation, Subap Plus (IP) capsules in patients with asymptomatic renal calculi of size ranging from 4 to 9 mm. Material and methods: This was a prospective, randomized, double-blind, placebo-controlled clinical trial conducted in a tertiary care hospital in Pune, India. Patients with asymptomatic renal calculi of 4e9 mm size were randomized (1:1, block randomization) to one of the group Subap Plus (treatment group) or placebo (placebo group). The study outcome included change in visual analog scale (VAS), change in the surface area and density of calculi and their expulsion. Statistical analysis was performed using student's t-test and Chi-square test. Results: A total of 120 patients were screened and 84 were enrolled who met the eligibility criteria, of which 65 patients completed the trial (treatment, n ¼ 34; placebo, n ¼ 31). The VAS score significantly decreased in the treatment group (6.9e1.8) than placebo group (7.2e6.8) (p < 0.001). The surface area and density were decreased by 47.58% (p < 0.008) and 43.01% (p < 0.001), respectively, in the treatment group than the placebo group. The expulsion of calculi was significantly higher in the treatment group than placebo group (20.59 vs. 3.23%, p < 0.03). Conclusion: Patients treated with herbal formulation showed better expulsion rate and reduction in surface area and density than the placebo group.
Journal of Ayurveda and Integrative Medicine
Indian Journal of Pathology and Microbiology
006495 Malik A;Borole A;Fanthome B;Veniyoor A;Misra R N INHS Asvini, Western Naval Command Hospit... more 006495 Malik A;Borole A;Fanthome B;Veniyoor A;Misra R N INHS Asvini, Western Naval Command Hospital, Mumbai , Prognostic correlation of tumor growth fraction and hormonal receptor status in breast carcinoma , 2007,50(1),142
Journal of Cancer Research and Therapeutics, 2012
Follicular dendritic cell sarcoma (FDCS) is a spindle cell neoplasm of histiocytic-dendritic cell... more Follicular dendritic cell sarcoma (FDCS) is a spindle cell neoplasm of histiocytic-dendritic cells origin. It is known to occur in lymph nodes and rarely has been reported in extranodal tissues like head and neck, mediastinum and gastrointestinal tract. We herein report the first FDCS arising from anal canal in a 56-year-old man. The tumor was composed of bland short spindle cells in focal whorl formation with interspersed few lymphocytes. The tumor cells were classically positive for CD21, CD23, CD35 and vimentin. Despite its misleading morphology, immunohistochemistry helped us to reach a conclusive diagnosis for relevant therapy.