Betsy Love - Academia.edu (original) (raw)

Papers by Betsy Love

Research paper thumbnail of Vascular Diseases of the Nervous System

Neurology in Clinical Practice, 2012

Research paper thumbnail of Vascular Diseases of the Nervous System

Neurology in Clinical Practice, 2008

Research paper thumbnail of Rare Genetic Disorders Predisposing to Stroke

Stroke in Children and Young Adults, 2009

Research paper thumbnail of Cardiac Disorders and Stroke in Children and Young Adults

Stroke in Children and Young Adults, 2009

Research paper thumbnail of Transesophageal Echocardiography in the Evaluation of Young Adults with Ischemic Stroke: Promises and Concerns

Cerebrovascular Diseases, 1995

Transesophageal echocardiography (TEE) is a valuable and sensitive test to screen for embolic car... more Transesophageal echocardiography (TEE) is a valuable and sensitive test to screen for embolic cardiac lesions. This procedure is recommended for the evaluation of most young adults with ischemic stroke. However, several questions about the role of TEE need to be addressed. Large studies that clarify the influence of the results of TEE on management are needed. Additional data about the

Research paper thumbnail of Diagnosis of Pulmonary Arteriovenous Malformation by Ultrafast Chest Computed Tomography in Rendu-Osler-Weber Syndrome with Cerebral Ischemia—A Case Report

Angiology, 1992

Pulmonary arteriovenous malformations occur in 15-20% of patients with Rendu-Osler-Weber syndrome... more Pulmonary arteriovenous malformations occur in 15-20% of patients with Rendu-Osler-Weber syndrome and can be the source of paradoxical emboli causing cerebral ischemia, septic emboli leading to brain abscesses, or polycythemia causing hyperviscosity and cerebral ischemia. The diagnosis of these malformations may be elusive, since classic clinical or radiologic findings may be absent in some patients. The authors report a patient with Rendu-Osler-Weber syndrome with cerebral ischemia who had normal findings from a pulmonary examination and chest roentgenogram. An ultrafast computed tomography scan of the chest demonstrated, however, a pulmonary arteriovenous malformation in the right upper lobe that was successfully resected. Ultrafast computed tomography of the chest is a relatively noninvasive method of screening for a pulmonary arteriovenous malformation in a patient with Rendu-Osler-Weber syndrome and otherwise unexplained neurologic symptoms.

Research paper thumbnail of Classification ofSubtype of AcuteIschemic Stroke Definitions forUseina Multicenter Clinical Trial

Marsh III, MD; and the TOAST Investigators Background and Purpose: The etiology of ischemic strok... more Marsh III, MD; and the TOAST Investigators Background and Purpose: The etiology of ischemic stroke affects prognosis, outcome, and management.

Research paper thumbnail of Stroke in Children and Young Adults

Stroke in Children and Young Adults, 2009

Research paper thumbnail of Antithrombotic Therapy for Ischemic Cerebrovascular Disease

Seminars in Neurology, 1991

1. Semin Neurol. 1991 Dec;11(4):353-67. Antithrombotic therapy for ischemic cerebrovascular disea... more 1. Semin Neurol. 1991 Dec;11(4):353-67. Antithrombotic therapy for ischemic cerebrovascular disease. Biller J, Love BB, Gordon DL. Department of Neurology, University of Iowa College of Medicine, Iowa City. PMID: 1811292 [PubMed - indexed for MEDLINE]. ...

Research paper thumbnail of Neurovascular System

Textbook of Clinical Neurology, 2007

Research paper thumbnail of Mitochondrial and metabolic causes of stroke

Uncommon Causes of Stroke, 2008

Research paper thumbnail of Stroke in Young Adults

Office Practice of Neurology, 2003

Research paper thumbnail of Antithrombotic Therapy for Ischemic Cerebrovascular Disease

Seminars in Neurology - SEMIN NEUROL, 1991

1. Semin Neurol. 1991 Dec;11(4):353-67. Antithrombotic therapy for ischemic cerebrovascular disea... more 1. Semin Neurol. 1991 Dec;11(4):353-67. Antithrombotic therapy for ischemic cerebrovascular disease. Biller J, Love BB, Gordon DL. Department of Neurology, University of Iowa College of Medicine, Iowa City. PMID: 1811292 [PubMed - indexed for MEDLINE]. ...

Research paper thumbnail of Mortality in Acute Cerebral Infarction in Young Adults A Ten-Year Experience

Angiology, 1991

We reviewed the one-month mortality among 213 patients aged fifteen to forty-five years (mean thi... more We reviewed the one-month mortality among 213 patients aged fifteen to forty-five years (mean thirty-five) with acute cerebral infarction (CI) evaluated during the period July 1, 1977, to February 1, 1988. Atherosclerotic cerebral infarction (ACI) was diagnosed in 59 (27.7%) patients, 53 (24.9%) had non-atherosclerotic vasculopathies (NAV); 46 (21.6%) had cardioembolic infarcts (CEI). Hematologically related disorders were diagnosed in 30 (14.1%) patients; the cause of CI could not be established in 25 (11.7%) patients. Fourteen patients (9 men, 5 women, mean age 34.8 years), (6.6%) died within thirty days of their CI: 7 had CEI (7/46,15.2%); 4 had ACI (4/59, 6.7%); and 3 had NAV (3/53, 5.6%). Our data suggest that young patients with acute CI have a thirty-day mortality rate lower than older patients. Deaths were most common in patients with CEI. Brain edema and herniation accounted for 6 (43%) of the deaths.

Research paper thumbnail of Design of the trial of Org 10172 in acute stroke treatment (TOAST)

Controlled Clinical Trials, 1997

TOAST is a multicenter, randomized, placebo-controlled clinical trial testing the usefulness of a... more TOAST is a multicenter, randomized, placebo-controlled clinical trial testing the usefulness of a new antithrombotic drug in improving the outcome of persons with acute ischemic stroke. Until recently, no clinical trial testing a treatment for ischemic stroke had demonstrated efficacy in outcome. Design problems of previously conducted trials with inconclusive results may partly explain their failures. During the design of TOAST, the investigators addressed several issues so the trial could test the treatment accurately. We report the strategies used in designing, implementing, and coordinating the trial.

Research paper thumbnail of Adverse Haematological Effects of Ticlopidine

Research paper thumbnail of Design of the trial of Org 10172 in acute stroke treatment (TOAST)

Controlled Clinical Trials, 1997

TOAST is a multicenter, randomized, placebo-controlled clinical trial testing the usefulness of a... more TOAST is a multicenter, randomized, placebo-controlled clinical trial testing the usefulness of a new antithrombotic drug in improving the outcome of persons with acute ischemic stroke. Until recently, no clinical trial testing a treatment for ischemic stroke had demonstrated efficacy in outcome. Design problems of previously conducted trials with inconclusive results may partly explain their failures. During the design of TOAST, the investigators addressed several issues so the trial could test the treatment accurately. We report the strategies used in designing, implementing, and coordinating the trial.

Research paper thumbnail of Transesophageal Echocardiography in the Evaluation of Young Adults with Ischemic Stroke: Promises and Concerns

Cerebrovascular Diseases, 1995

Transesophageal echocardiography (TEE) is a valuable and sensitive test to screen for embolic car... more Transesophageal echocardiography (TEE) is a valuable and sensitive test to screen for embolic cardiac lesions. This procedure is recommended for the evaluation of most young adults with ischemic stroke. However, several questions about the role of TEE need to be addressed. Large studies that clarify the influence of the results of TEE on management are needed. Additional data about the

Research paper thumbnail of Cigarette Smoking

Archives of Neurology, 1990

Research paper thumbnail of Vascular Diseases of the Nervous System

Neurology in Clinical Practice, 2012

Research paper thumbnail of Vascular Diseases of the Nervous System

Neurology in Clinical Practice, 2008

Research paper thumbnail of Rare Genetic Disorders Predisposing to Stroke

Stroke in Children and Young Adults, 2009

Research paper thumbnail of Cardiac Disorders and Stroke in Children and Young Adults

Stroke in Children and Young Adults, 2009

Research paper thumbnail of Transesophageal Echocardiography in the Evaluation of Young Adults with Ischemic Stroke: Promises and Concerns

Cerebrovascular Diseases, 1995

Transesophageal echocardiography (TEE) is a valuable and sensitive test to screen for embolic car... more Transesophageal echocardiography (TEE) is a valuable and sensitive test to screen for embolic cardiac lesions. This procedure is recommended for the evaluation of most young adults with ischemic stroke. However, several questions about the role of TEE need to be addressed. Large studies that clarify the influence of the results of TEE on management are needed. Additional data about the

Research paper thumbnail of Diagnosis of Pulmonary Arteriovenous Malformation by Ultrafast Chest Computed Tomography in Rendu-Osler-Weber Syndrome with Cerebral Ischemia—A Case Report

Angiology, 1992

Pulmonary arteriovenous malformations occur in 15-20% of patients with Rendu-Osler-Weber syndrome... more Pulmonary arteriovenous malformations occur in 15-20% of patients with Rendu-Osler-Weber syndrome and can be the source of paradoxical emboli causing cerebral ischemia, septic emboli leading to brain abscesses, or polycythemia causing hyperviscosity and cerebral ischemia. The diagnosis of these malformations may be elusive, since classic clinical or radiologic findings may be absent in some patients. The authors report a patient with Rendu-Osler-Weber syndrome with cerebral ischemia who had normal findings from a pulmonary examination and chest roentgenogram. An ultrafast computed tomography scan of the chest demonstrated, however, a pulmonary arteriovenous malformation in the right upper lobe that was successfully resected. Ultrafast computed tomography of the chest is a relatively noninvasive method of screening for a pulmonary arteriovenous malformation in a patient with Rendu-Osler-Weber syndrome and otherwise unexplained neurologic symptoms.

Research paper thumbnail of Classification ofSubtype of AcuteIschemic Stroke Definitions forUseina Multicenter Clinical Trial

Marsh III, MD; and the TOAST Investigators Background and Purpose: The etiology of ischemic strok... more Marsh III, MD; and the TOAST Investigators Background and Purpose: The etiology of ischemic stroke affects prognosis, outcome, and management.

Research paper thumbnail of Stroke in Children and Young Adults

Stroke in Children and Young Adults, 2009

Research paper thumbnail of Antithrombotic Therapy for Ischemic Cerebrovascular Disease

Seminars in Neurology, 1991

1. Semin Neurol. 1991 Dec;11(4):353-67. Antithrombotic therapy for ischemic cerebrovascular disea... more 1. Semin Neurol. 1991 Dec;11(4):353-67. Antithrombotic therapy for ischemic cerebrovascular disease. Biller J, Love BB, Gordon DL. Department of Neurology, University of Iowa College of Medicine, Iowa City. PMID: 1811292 [PubMed - indexed for MEDLINE]. ...

Research paper thumbnail of Neurovascular System

Textbook of Clinical Neurology, 2007

Research paper thumbnail of Mitochondrial and metabolic causes of stroke

Uncommon Causes of Stroke, 2008

Research paper thumbnail of Stroke in Young Adults

Office Practice of Neurology, 2003

Research paper thumbnail of Antithrombotic Therapy for Ischemic Cerebrovascular Disease

Seminars in Neurology - SEMIN NEUROL, 1991

1. Semin Neurol. 1991 Dec;11(4):353-67. Antithrombotic therapy for ischemic cerebrovascular disea... more 1. Semin Neurol. 1991 Dec;11(4):353-67. Antithrombotic therapy for ischemic cerebrovascular disease. Biller J, Love BB, Gordon DL. Department of Neurology, University of Iowa College of Medicine, Iowa City. PMID: 1811292 [PubMed - indexed for MEDLINE]. ...

Research paper thumbnail of Mortality in Acute Cerebral Infarction in Young Adults A Ten-Year Experience

Angiology, 1991

We reviewed the one-month mortality among 213 patients aged fifteen to forty-five years (mean thi... more We reviewed the one-month mortality among 213 patients aged fifteen to forty-five years (mean thirty-five) with acute cerebral infarction (CI) evaluated during the period July 1, 1977, to February 1, 1988. Atherosclerotic cerebral infarction (ACI) was diagnosed in 59 (27.7%) patients, 53 (24.9%) had non-atherosclerotic vasculopathies (NAV); 46 (21.6%) had cardioembolic infarcts (CEI). Hematologically related disorders were diagnosed in 30 (14.1%) patients; the cause of CI could not be established in 25 (11.7%) patients. Fourteen patients (9 men, 5 women, mean age 34.8 years), (6.6%) died within thirty days of their CI: 7 had CEI (7/46,15.2%); 4 had ACI (4/59, 6.7%); and 3 had NAV (3/53, 5.6%). Our data suggest that young patients with acute CI have a thirty-day mortality rate lower than older patients. Deaths were most common in patients with CEI. Brain edema and herniation accounted for 6 (43%) of the deaths.

Research paper thumbnail of Design of the trial of Org 10172 in acute stroke treatment (TOAST)

Controlled Clinical Trials, 1997

TOAST is a multicenter, randomized, placebo-controlled clinical trial testing the usefulness of a... more TOAST is a multicenter, randomized, placebo-controlled clinical trial testing the usefulness of a new antithrombotic drug in improving the outcome of persons with acute ischemic stroke. Until recently, no clinical trial testing a treatment for ischemic stroke had demonstrated efficacy in outcome. Design problems of previously conducted trials with inconclusive results may partly explain their failures. During the design of TOAST, the investigators addressed several issues so the trial could test the treatment accurately. We report the strategies used in designing, implementing, and coordinating the trial.

Research paper thumbnail of Adverse Haematological Effects of Ticlopidine

Research paper thumbnail of Design of the trial of Org 10172 in acute stroke treatment (TOAST)

Controlled Clinical Trials, 1997

TOAST is a multicenter, randomized, placebo-controlled clinical trial testing the usefulness of a... more TOAST is a multicenter, randomized, placebo-controlled clinical trial testing the usefulness of a new antithrombotic drug in improving the outcome of persons with acute ischemic stroke. Until recently, no clinical trial testing a treatment for ischemic stroke had demonstrated efficacy in outcome. Design problems of previously conducted trials with inconclusive results may partly explain their failures. During the design of TOAST, the investigators addressed several issues so the trial could test the treatment accurately. We report the strategies used in designing, implementing, and coordinating the trial.

Research paper thumbnail of Transesophageal Echocardiography in the Evaluation of Young Adults with Ischemic Stroke: Promises and Concerns

Cerebrovascular Diseases, 1995

Transesophageal echocardiography (TEE) is a valuable and sensitive test to screen for embolic car... more Transesophageal echocardiography (TEE) is a valuable and sensitive test to screen for embolic cardiac lesions. This procedure is recommended for the evaluation of most young adults with ischemic stroke. However, several questions about the role of TEE need to be addressed. Large studies that clarify the influence of the results of TEE on management are needed. Additional data about the

Research paper thumbnail of Cigarette Smoking

Archives of Neurology, 1990