Michael Bissell - Academia.edu (original) (raw)

Uploads

Papers by Michael Bissell

Research paper thumbnail of Laboratory-Related Measures of Patient Outcomes: An Introduction. Michael G. Bissell, ed. Washington, DC: AACC Press, 2000, 193 pp., <span class="katex"><span class="katex-mathml"><math xmlns="http://www.w3.org/1998/Math/MathML"><semantics><mrow><mn>49</mn><mo stretchy="false">(</mo></mrow><annotation encoding="application/x-tex">49 (</annotation></semantics></math></span><span class="katex-html" aria-hidden="true"><span class="base"><span class="strut" style="height:1em;vertical-align:-0.25em;"></span><span class="mord">49</span><span class="mopen">(</span></span></span></span>39 AACC members). ISBN 1-890883-26-3

Research paper thumbnail of Time series modeling for quality control in clinical chemistry

Clinical Chemistry, 1988

Autocorrelation of clinical chemistry quality-control (Q/C) measurements causes one of the basic ... more Autocorrelation of clinical chemistry quality-control (Q/C) measurements causes one of the basic assumptions underlying the use of Levey-Jennings control charts to be violated and performance to be degraded. This is the requirement that the observations be statistically independent. We present a proposal for a new approach to statistical quality control that removes this difficulty. We propose to replace the current single control chart of raw Q/C data with two charts: (a) a common cause chart, representing a Box-Jenkins ARIMA time-series model of any underlying persisting nonrandomness in the process, and (b) a special cause chart of the residuals from the above model, which, being free of such persisting nonrandomness, fulfills the criteria for use of the standard Levey-Jennings plotting format and standard control rules. We provide a comparison of the performance of our proposed approach with that of current practice.

Research paper thumbnail of Clinical Application of Capillary Isoelectric Focusing on Fused Silica Capillary for Determination of Hemoglobin Variants

Research paper thumbnail of Micellar electrokinetic capillary chromatographic separation of steroids in urine by trioctylphosphine oxide and cationic surfactant

Journal of Chromatography B: Biomedical Sciences and Applications, 1995

Research paper thumbnail of Apparatus and method for interfacing an open capillary and detector for conducting off-column analyses

Research paper thumbnail of Case studies in ethics. Manager in the middle

Clinical leadership & management review : the journal of CLMA

Research paper thumbnail of Application of SELDI-TOF mass spectrometry in clinical evaluation of thrombotic thrombocytopenic purpura

Spectroscopy, 2006

Surface Enhanced Laser Desorption/Ionization Time Of Flight (SELDI-TOF) mass spectrometry is char... more Surface Enhanced Laser Desorption/Ionization Time Of Flight (SELDI-TOF) mass spectrometry is characterized by integration of mass spectrometry with surface chemistry, which gives rise to rapid purification and subsequent determination of protein/peptide analytes. There are several surface matrices, named proteinChips, available for analyzing a particular analyte or a subset of biomolecules in biological samples. Each proteinChip has a unique surface property suitable for fractionation of a specific group of molecules. This article demonstrates the application of SELDI-TOF for the analysis of a cleaved peptide (Mr7739 daltons) from von Willebrand Factor by a metalloproteinase, ADAMTS13. Deficiency of ADAMTS13 is a known primary risk factor for the devastating hematological disorder, Thrombotic thrombocytopenic purpura (TTP). Rapid determination of ADAMTS13 activity helps clinicians tremendously in making the correct diagnosis and initiating timely therapy. Most patients with TTP are ...

Research paper thumbnail of Accuracy of Portable Blood Glucose Monitoring: Effect of Glucose Level and Prandial State

American Journal of Clinical Pathology, 1991

Glucose was determined on capillary and venous blood samples from 274 adult diabetics by three di... more Glucose was determined on capillary and venous blood samples from 274 adult diabetics by three different methodologies: the Glucoscan 2000 and Accu-Check II portable glucose meters (capillary) and the Kodak Ektachem 700 analyzer (venous). Both glucose meters correlated significantly with the Ektachem results. A significant positive bias was found for the Glucoscan compared with Ektachem, not found with the Accu-Check II. The Accu-Check performed better than the Glucoscan at venous plasma glucose levels less than 1 g/L. The mean error of Glucoscan determinations was significantly greater and biased positive when the measurement was performed within 4 hours of eating, whereas no such effect was seen with Accu-Check error. Multiple regression analysis revealed that the Glucoscan measurement was independently influenced by both venous plasma glucose and prandial state, whereas the Accu-Check II measurement was not dependent on either variable. The within-run precision for both glucose meters were comparable.

Research paper thumbnail of Newborn screening: speaking out on state program

Clinical leadership & management review : the journal of CLMA, Jan 30, 2006

Research paper thumbnail of Regulatory issues in accreditation of toxicology laboratories

Clinics in laboratory medicine, 2012

Clinical toxicology laboratories and forensic toxicology laboratories operate in a highly regulat... more Clinical toxicology laboratories and forensic toxicology laboratories operate in a highly regulated environment. This article outlines major US legal/regulatory issues and requirements relevant to accreditation of toxicology laboratories (state and local regulations are not covered in any depth). The most fundamental regulatory distinction involves the purposes for which the laboratory operates: clinical versus nonclinical. The applicable regulations and the requirements and options for operations depend most basically on this consideration, with clinical toxicology laboratories being directly subject to federal law including mandated options for accreditation and forensic toxicology laboratories being subject to degrees of voluntary or state government–required accreditation.

Research paper thumbnail of Toxicology testing

Clinics in laboratory medicine, 2012

Research paper thumbnail of STAT Turnaround Time: Satellite and Point-to-Point Testing

Laboratory Medicine, 1996

Research paper thumbnail of Beware of unwritten institutional policies

Clinical leadership & management review : the journal of CLMA, Jan 28, 2007

Research paper thumbnail of Answering questions from the public

Clinical leadership & management review : the journal of CLMA, Jan 30, 2007

Research paper thumbnail of Prototype integration of protein electrophoresis laboratory results in an information warehouse to improve workflow and data analysis

AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium, 2006

This poster demonstrates our efforts to enhance workflow and clinical analysis of protein electro... more This poster demonstrates our efforts to enhance workflow and clinical analysis of protein electrophoresis (PEP) data through integration with the Information Warehouse (IW) at The Ohio State University Medical Center (OSUMC). A new desktop application has been developed with the aim of enabling more efficient and accurate gel analysis by clinical pathologists. This tool gives the pathologists the ability to perform their analysis conveniently from anywhere on the OSUMC network along with the aid of numerical analysis algorithms, image enhancement techniques, and access to historical PEP results for the given patient.

Research paper thumbnail of There is no such thing as free pizza

Clinical leadership & management review : the journal of CLMA, Jan 28, 2006

For many years, it has been standard practice in the United States to allow pharmaceutical repres... more For many years, it has been standard practice in the United States to allow pharmaceutical representatives to provide drug samples, pens, note pads, visual aids, t-shirts, etc., and pay for attendee meals in conjunction with teaching conferences for hospital physicians. The "gifts" typically aren't as luxurious in the clinical laboratory, but even so, is any vendor freebie too much?

Research paper thumbnail of Bad blood" in the cytology lab

Clinical leadership & management review : the journal of CLMA, Jan 27, 2005

Research paper thumbnail of Blowing the whistle on poor laboratory performances

Clinical leadership & management review : the journal of CLMA, Jan 27, 2005

Research paper thumbnail of Learning from adverse events in clinical studies: a proposal

Clinical leadership & management review : the journal of CLMA

Research paper thumbnail of Information systems and human error in the lab

Clinical leadership & management review : the journal of CLMA

Health system costs in clinical laboratories are incurred daily due to human error. Indeed, a maj... more Health system costs in clinical laboratories are incurred daily due to human error. Indeed, a major impetus for automating clinical laboratories has always been the opportunity it presents to simultaneously reduce cost and improve quality of operations by decreasing human error. But merely automating these processes is not enough. To the extent that introduction of these systems results in operators having less practice in dealing with unexpected events or becoming deskilled in problemsolving, however new kinds of error will likely appear. Clinical laboratories could potentially benefit by integrating findings on human error from modern behavioral science into their operations. Fully understanding human error requires a deep understanding of human information processing and cognition. Predicting and preventing negative consequences requires application of this understanding to laboratory operations. Although the occurrence of a particular error at a particular instant cannot be abso...

Research paper thumbnail of Laboratory-Related Measures of Patient Outcomes: An Introduction. Michael G. Bissell, ed. Washington, DC: AACC Press, 2000, 193 pp., <span class="katex"><span class="katex-mathml"><math xmlns="http://www.w3.org/1998/Math/MathML"><semantics><mrow><mn>49</mn><mo stretchy="false">(</mo></mrow><annotation encoding="application/x-tex">49 (</annotation></semantics></math></span><span class="katex-html" aria-hidden="true"><span class="base"><span class="strut" style="height:1em;vertical-align:-0.25em;"></span><span class="mord">49</span><span class="mopen">(</span></span></span></span>39 AACC members). ISBN 1-890883-26-3

Research paper thumbnail of Time series modeling for quality control in clinical chemistry

Clinical Chemistry, 1988

Autocorrelation of clinical chemistry quality-control (Q/C) measurements causes one of the basic ... more Autocorrelation of clinical chemistry quality-control (Q/C) measurements causes one of the basic assumptions underlying the use of Levey-Jennings control charts to be violated and performance to be degraded. This is the requirement that the observations be statistically independent. We present a proposal for a new approach to statistical quality control that removes this difficulty. We propose to replace the current single control chart of raw Q/C data with two charts: (a) a common cause chart, representing a Box-Jenkins ARIMA time-series model of any underlying persisting nonrandomness in the process, and (b) a special cause chart of the residuals from the above model, which, being free of such persisting nonrandomness, fulfills the criteria for use of the standard Levey-Jennings plotting format and standard control rules. We provide a comparison of the performance of our proposed approach with that of current practice.

Research paper thumbnail of Clinical Application of Capillary Isoelectric Focusing on Fused Silica Capillary for Determination of Hemoglobin Variants

Research paper thumbnail of Micellar electrokinetic capillary chromatographic separation of steroids in urine by trioctylphosphine oxide and cationic surfactant

Journal of Chromatography B: Biomedical Sciences and Applications, 1995

Research paper thumbnail of Apparatus and method for interfacing an open capillary and detector for conducting off-column analyses

Research paper thumbnail of Case studies in ethics. Manager in the middle

Clinical leadership & management review : the journal of CLMA

Research paper thumbnail of Application of SELDI-TOF mass spectrometry in clinical evaluation of thrombotic thrombocytopenic purpura

Spectroscopy, 2006

Surface Enhanced Laser Desorption/Ionization Time Of Flight (SELDI-TOF) mass spectrometry is char... more Surface Enhanced Laser Desorption/Ionization Time Of Flight (SELDI-TOF) mass spectrometry is characterized by integration of mass spectrometry with surface chemistry, which gives rise to rapid purification and subsequent determination of protein/peptide analytes. There are several surface matrices, named proteinChips, available for analyzing a particular analyte or a subset of biomolecules in biological samples. Each proteinChip has a unique surface property suitable for fractionation of a specific group of molecules. This article demonstrates the application of SELDI-TOF for the analysis of a cleaved peptide (Mr7739 daltons) from von Willebrand Factor by a metalloproteinase, ADAMTS13. Deficiency of ADAMTS13 is a known primary risk factor for the devastating hematological disorder, Thrombotic thrombocytopenic purpura (TTP). Rapid determination of ADAMTS13 activity helps clinicians tremendously in making the correct diagnosis and initiating timely therapy. Most patients with TTP are ...

Research paper thumbnail of Accuracy of Portable Blood Glucose Monitoring: Effect of Glucose Level and Prandial State

American Journal of Clinical Pathology, 1991

Glucose was determined on capillary and venous blood samples from 274 adult diabetics by three di... more Glucose was determined on capillary and venous blood samples from 274 adult diabetics by three different methodologies: the Glucoscan 2000 and Accu-Check II portable glucose meters (capillary) and the Kodak Ektachem 700 analyzer (venous). Both glucose meters correlated significantly with the Ektachem results. A significant positive bias was found for the Glucoscan compared with Ektachem, not found with the Accu-Check II. The Accu-Check performed better than the Glucoscan at venous plasma glucose levels less than 1 g/L. The mean error of Glucoscan determinations was significantly greater and biased positive when the measurement was performed within 4 hours of eating, whereas no such effect was seen with Accu-Check error. Multiple regression analysis revealed that the Glucoscan measurement was independently influenced by both venous plasma glucose and prandial state, whereas the Accu-Check II measurement was not dependent on either variable. The within-run precision for both glucose meters were comparable.

Research paper thumbnail of Newborn screening: speaking out on state program

Clinical leadership & management review : the journal of CLMA, Jan 30, 2006

Research paper thumbnail of Regulatory issues in accreditation of toxicology laboratories

Clinics in laboratory medicine, 2012

Clinical toxicology laboratories and forensic toxicology laboratories operate in a highly regulat... more Clinical toxicology laboratories and forensic toxicology laboratories operate in a highly regulated environment. This article outlines major US legal/regulatory issues and requirements relevant to accreditation of toxicology laboratories (state and local regulations are not covered in any depth). The most fundamental regulatory distinction involves the purposes for which the laboratory operates: clinical versus nonclinical. The applicable regulations and the requirements and options for operations depend most basically on this consideration, with clinical toxicology laboratories being directly subject to federal law including mandated options for accreditation and forensic toxicology laboratories being subject to degrees of voluntary or state government–required accreditation.

Research paper thumbnail of Toxicology testing

Clinics in laboratory medicine, 2012

Research paper thumbnail of STAT Turnaround Time: Satellite and Point-to-Point Testing

Laboratory Medicine, 1996

Research paper thumbnail of Beware of unwritten institutional policies

Clinical leadership & management review : the journal of CLMA, Jan 28, 2007

Research paper thumbnail of Answering questions from the public

Clinical leadership & management review : the journal of CLMA, Jan 30, 2007

Research paper thumbnail of Prototype integration of protein electrophoresis laboratory results in an information warehouse to improve workflow and data analysis

AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium, 2006

This poster demonstrates our efforts to enhance workflow and clinical analysis of protein electro... more This poster demonstrates our efforts to enhance workflow and clinical analysis of protein electrophoresis (PEP) data through integration with the Information Warehouse (IW) at The Ohio State University Medical Center (OSUMC). A new desktop application has been developed with the aim of enabling more efficient and accurate gel analysis by clinical pathologists. This tool gives the pathologists the ability to perform their analysis conveniently from anywhere on the OSUMC network along with the aid of numerical analysis algorithms, image enhancement techniques, and access to historical PEP results for the given patient.

Research paper thumbnail of There is no such thing as free pizza

Clinical leadership & management review : the journal of CLMA, Jan 28, 2006

For many years, it has been standard practice in the United States to allow pharmaceutical repres... more For many years, it has been standard practice in the United States to allow pharmaceutical representatives to provide drug samples, pens, note pads, visual aids, t-shirts, etc., and pay for attendee meals in conjunction with teaching conferences for hospital physicians. The "gifts" typically aren't as luxurious in the clinical laboratory, but even so, is any vendor freebie too much?

Research paper thumbnail of Bad blood" in the cytology lab

Clinical leadership & management review : the journal of CLMA, Jan 27, 2005

Research paper thumbnail of Blowing the whistle on poor laboratory performances

Clinical leadership & management review : the journal of CLMA, Jan 27, 2005

Research paper thumbnail of Learning from adverse events in clinical studies: a proposal

Clinical leadership & management review : the journal of CLMA

Research paper thumbnail of Information systems and human error in the lab

Clinical leadership & management review : the journal of CLMA

Health system costs in clinical laboratories are incurred daily due to human error. Indeed, a maj... more Health system costs in clinical laboratories are incurred daily due to human error. Indeed, a major impetus for automating clinical laboratories has always been the opportunity it presents to simultaneously reduce cost and improve quality of operations by decreasing human error. But merely automating these processes is not enough. To the extent that introduction of these systems results in operators having less practice in dealing with unexpected events or becoming deskilled in problemsolving, however new kinds of error will likely appear. Clinical laboratories could potentially benefit by integrating findings on human error from modern behavioral science into their operations. Fully understanding human error requires a deep understanding of human information processing and cognition. Predicting and preventing negative consequences requires application of this understanding to laboratory operations. Although the occurrence of a particular error at a particular instant cannot be abso...