Andrea Borgonovo - Academia.edu (original) (raw)

Papers by Andrea Borgonovo

Research paper thumbnail of TGF-beta1 and VEGF after fresh frozen bone allograft insertion in oral-maxillo-facial surgery

Histology and histopathology, 2010

Bone regeneration technique using allografts is widely used in oral surgery to repair alveolar de... more Bone regeneration technique using allografts is widely used in oral surgery to repair alveolar defects and to increase alveolar volume for endosseous implant insertions. Bone allografts promote the reabsorption and neo-synthesis of bone tissue, which are regulated by numerous cytokines, proteins and growth factors. In this study, six patients with insufficient alveolar volume for endosseous implant insertions, were treated with bone regeneration technique using Fresh Frozen Bone (FFB) allografts collected from the femoral head or the hip. Samples of bone graft collected during graft insertion surgery and biopsies collected six months later during implantology were fixed, decalcified and analyzed histomorphologically and morphometrically by haematoxylin-eosin staining. In addition, TGF-beta1 and VEGF were analyzed by immunohistochemistry. The histological analysis of FFBs showed wide areas of calcified bone organized in osteons intermingled with areas of non-calcified matrix containi...

Research paper thumbnail of Analysis of Forces Applied During Transalveolar Sinus Lift: A Preliminary Clinical Study

Implant dentistry, Jan 27, 2018

To introduce a novel modality that enables the measurement of forces applied during a transalveol... more To introduce a novel modality that enables the measurement of forces applied during a transalveolar sinus floor elevation (tSFE) and to investigate the influence of anatomical and surgical factors on the necessitated force in sinus membrane detachment. A new endosinus probe, innovated with a calibrated load cell, was used to test the forces needed to perforate ten maxillary sinuses in 5 human cadavers. The same probe was also used to detach the Schneiderian membrane from the bony floor of 21 human subjects undergoing tSFE. The force needed to cause membrane perforation in the cadaver sample was on average 3.46 ± 1.04 N. The maximum force applied in vivo to a sinus membrane without perforation was 2.01 ± 0.67 N on average. Regression analysis showed that smoking (P < 0.001), as well as 3.0 mm osteotomy (P < 0.001), was significantly correlated to increased forces during membrane detachment. The maximum force needed to detach the membrane was found to be, on average, lower than ...

Research paper thumbnail of Microbiological analysis of bacterial plaque on three different threads in oral surgery

Minerva stomatologica, 2017

Suture is the final act of most oral surgery procedures. The quality of healing after the operati... more Suture is the final act of most oral surgery procedures. The quality of healing after the operation depends on its efficiency. Sutures must not cause inflammation - neither directly nor indirectly. The objective of this study is to compare the bacterial colonization on different suture materials after a third molar extraction. Thirty patients were randomly selected among people going under third molar extraction; they were divided into 3 groups and one suture type was used on each group. After 7 days distal stitches were removed by a single operator, placed in physiologic solution and analyzed after 2 or 3 hours. Patients followed the same postsurgical protocols; materials used were: Ethicon Silk® 4/0, B. Braun Dafilon® 4/0, and B. Braun Safil® 4/0. The amount of cocci and bacilli on the sutures analyzed shows that silk (Ethicon Silk) is the higher level of retention material where monofilament (B. Braun Dafilon) is the lower. There is a difference between monofilament and polyglyco...

Research paper thumbnail of Incidence and characteristics of mandibular accessory canals: A radiographic investigation

Journal of Investigative and Clinical Dentistry, 2017

Aim: The aim of the present study was to explore, through tridimensional reconstructions of cone-... more Aim: The aim of the present study was to explore, through tridimensional reconstructions of cone-beam computed tomography (CBCT) scans, the presence and the characteristics of mandibular accessory canals. Methods: For each included participant, the presence of accessory canals was recorded. The diameter of the canal, as well as the distance between the canal walls and the walls of the mandibular bone (lingual, buccal, cranial and caudal), were measured and recorded. Results: Mandibular accessory canals could be found in 8.8% of participants. Retromolar canals were the most frequently found accessory mandibular canals. Conclusions: Accessory mandibular canals were found in a relatively high number of participants through the examination of CBCT scans and tridimensional reconstruction. The presence of such structures should be considered cautiously when planning and performing surgical interventions in mandibular area.

Research paper thumbnail of CBCT evaluation of the tridimensional relationship between impacted lower third molar and the inferior alveolar nerve position

Minerva stomatologica, 2017

The aim of this study is to evaluate if the statistical significant relations between the measure... more The aim of this study is to evaluate if the statistical significant relations between the measures taken exists or not and to show how the 3D reconstruction could be help the oral surgeon in all those instances in which it may have a direct impact on the planning of the surgical steps. Thanks to use of NobelClinician™ Software it was possible to analyze 200 mandibular tomography computerized, random selected, and create a 3D reconstruction of mandibular bone, point out dental structure of wisdom tooth and the way of IAN. Statistical analysis was performed using the Statistical Package for Social Sciences. One way ANOVA test was used to measure the association between each independent variable and the outcome variable, followed by the post-hoc least significant difference (LSD) test for intergroup differences. Two independent variables were significant predictors for risk to have the distance 0 mm from IAN to apex: "Ramus relationship/space available" and "depth"....

Research paper thumbnail of Sinus presurgical evaluation: a literature review and a new classification proposal

Minerva stomatologica, Jan 15, 2017

Presurgical evaluation with cone beam computed tomography (CBCT) or computed tomography (CT) has ... more Presurgical evaluation with cone beam computed tomography (CBCT) or computed tomography (CT) has become an essential tool for diagnosis and surgical planning, including maxillary sinus floor elevation. Before performing a sinus lift, the clinician's attention should not be only directed to the patency of the ostium through CBCT or CT, because many anatomical features could influence the surgical approach of sinus floor elevation. The goal of this article was to facilitate the communication between clinicians regarding the type of maxillary sinus, encourage in-depth analysis prior to surgery and reduce the risk of complications due to possible underestimation of important parameters. An electronic search was conducted in Pubmed, Embase, Medline and Scopus, matching the following keywords: "sinus lift", "CBCT", "CT", "presurgical" and "evaluation". Clinical Oral Implant Research, Implant Dentistry, International Journal of Periodon...

Research paper thumbnail of Infection Related Inferior Alveolar Nerve Paresthesia in the Lower Premolar Teeth

Case Reports in Dentistry, 2016

Introduction. The aim of this paper was to describe two cases of IAN infection-induced paresthesi... more Introduction. The aim of this paper was to describe two cases of IAN infection-induced paresthesia and to discuss the most appropriate treatment solutions.Methods. For two patients, periapical lesions that induced IAN paresthesia were revealed. In the first case, the tooth was previously endodontically treated, whereas in the second case the lesion was due to pulp necrosis.Results. For the first patient, a progressive healing was observed only after the tooth extraction. In the second patient, the paresthesia had resolved after endodontic treatment.Conclusions. The endodontic-related paresthesia is a rare complication that can be the result of a combination of etiopathogenic mechanisms such as mechanical pressure on the nerve fibers due to the expanding infectious process and the production of microbial toxins. Paresthesia resulting from periapical lesions usually subsides through elimination of infection by root canal treatment. However, if there are no signs of enhancement, the im...

Research paper thumbnail of Zirconia Implants in Esthetic Areas: 4-Year Follow-Up Evaluation Study

International Journal of Dentistry, 2015

Objectives.The aim is to evaluate the survival and success rates, as well as the marginal bone lo... more Objectives.The aim is to evaluate the survival and success rates, as well as the marginal bone loss (MBL) and periodontal indexes of zirconia implants positioned in the esthetic jaw areas.Materials and Method.13 patients were selected and 20 one-piece zirconia implants were used for the rehabilitation of single tooth or partially edentulous ridge in the esthetic jaw areas. Six months after surgery and then once a year, a clinical-radiographic evaluation was performed in order to estimate peri-implant tissue health and marginal bone loss.Results.The survival and success rates were 100%. The average marginal bone loss from baseline to 48 months after surgery was +2.1 mm. Four years after surgery, the median and the mode for visible Plaque Index and Bleeding On Probing resulted 1 whereas Probing Pocket Depth amounted to 3 mm (SD = ±0.49 mm).Conclusion.One-piece zirconia dental implants are characterized by high biocompatibility, low plaque adhesion, and absence of microgap that can be ...

Research paper thumbnail of Radiotrasparenza dell’angolo mandibolare. Due casi di lacuna di Stafne

Dental Cadmos, 2011

ObjectivesTo describe two Stafne bone cavity cases, focusing on instrumental investigations besid... more ObjectivesTo describe two Stafne bone cavity cases, focusing on instrumental investigations besides pathogenesis, in order to reach correct differential diagnosis and therapy.

Research paper thumbnail of Cisti del dotto nasopalatino di notevoli dimensioni: presentazione di un caso clinico e follow-up

Dental Cadmos, 2011

ABSTRACT Objectives The main objective of this article is to describe the surgical approach used ... more ABSTRACT Objectives The main objective of this article is to describe the surgical approach used for the enucleation of an unusually large nasopalatine cyst and the long-term results obtained.

Research paper thumbnail of Clinical evaluation of zirconium dental implants placed in esthetic areas: a case series study

The European journal of esthetic dentistry : official journal of the European Academy of Esthetic Dentistry, 2013

The purpose of this study was to evaluate the esthetic result of monophasic zirconium dental impl... more The purpose of this study was to evaluate the esthetic result of monophasic zirconium dental implants, placed in the highly esthetic areas of the jaws. In this case series the results of 12 monophasic zirconium dental implants placed in highly esthetic areas of 8 patients (6 male and 2 female). For each implant the Pink Esthetic Score (PES) and the White Esthetic Score (WES) were evaluated. All implants were inserted in fresh postextraction sites. The esthetic parameters PES/ WES has given a total average value of 15.5 ± 1.5. Analyzing the two indices individually, the PES has given a value equal to 7.5 ± 1 and the WES has given a value equal to 8 ± 1.13. Both values obtained indicate the achievement of an absolutely satisfactory esthetic result. Within the limits of this study, the zirconium dental implants seems to give excellent results with regard to the esthetic result and for the maintenance of peri-implant soft tissues.

Research paper thumbnail of Behavior of endosseous one-piece yttrium stabilized zirconia dental implants placed in posterior areas

Minerva stomatologica

Considering that zirconia dental implants are indicated for the rehabilitation of highly esthetic... more Considering that zirconia dental implants are indicated for the rehabilitation of highly esthetic areas, the aim of this work was to investigate the functional behavior of these implants positioned in the posterior regions of the jaws. The study included 6 patients with 14 zirconia implants positioned in posterior (molar) areas of the jaws. Immediately after surgery, all implants were restored with temporary crowns or bridges. Clinical radiographic evaluation was performed 6 months after surgery and subsequently every year. At these follow-up visits, periodontal indexes were recorded and peri-apical radiographs were taken in order to calculate marginal bone loss. The success and survival rates were 100%. The modified bleeding index (mBI) and modified plaque index (mPLI) were respectively equal to 0.57±0.51 and 0.29 ± 0.47 at 4-year follow-up. The overall mean probing depth of the implants was 3.13±0.87 mm. The mean marginal bone loss was +0.665 mm 4 years after surgery. Considering ...

Research paper thumbnail of An uncommon clinical feature of IAN injury after third molar removal: a delayed paresthesia case series and literature review

Quintessence international (Berlin, Germany : 1985), 2012

After an inferior alveolar nerve (IAN) injury, the onset of altered sensation usually begins imme... more After an inferior alveolar nerve (IAN) injury, the onset of altered sensation usually begins immediately after surgery. However, it sometimes begins after several days, which is referred to as delayed paresthesia. The authors considered three different etiologies that likely produce inflammation along the nerve trunk and cause delayed paresthesia: compression of the clot, fibrous reorganization of the clot, and nerve trauma caused by bone fragments during clot organization. The aim of this article was to evaluate the etiology of IAN delayed paresthesia, analyze the literature, present a case series related to three different causes of this pathology, and compare delayed paresthesia with the classic immediate symptomatic paresthesia.

Research paper thumbnail of Esthetic Rehabilitation of a Severely Compromised Anterior Area: Combined Periodontal and Restorative Approach

Case Reports in Dentistry, 2014

The complete oral rehabilitation of patients demanding a beautiful and attractive smile involves ... more The complete oral rehabilitation of patients demanding a beautiful and attractive smile involves a multidisciplinary approach that includes the change of both the morphological aspect of the teeth and the architecture of gum tissues. This clinical report describes a successful interdisciplinary approach for the treatment of an esthetically compromised dentition. In a first phase, the periodontal plastic surgery was performed for root coverage and, in particular, it was decided for the execution of a coronally advanced flap for the treatment of multiple recession defects. Once complete healing of soft tissues was obtained, six lithium disilicate veneers were placed over the anterior maxillary teeth. Lithium disilicate is a glass-based ceramic which presents excellent aesthetics and allows the passage of light without creating unnatural reflections. This feature has made it possible to recreate a natural aspect of teeth that in combination with the harmonic architecture of soft tissue...

Research paper thumbnail of Treatment of the Atrophic Upper Jaw: Rehabilitation of Two Complex Cases

Case Reports in Dentistry, 2013

In reconstructive surgery, the fresh frozen homologous bone (FFB) represents a valid alternative ... more In reconstructive surgery, the fresh frozen homologous bone (FFB) represents a valid alternative to the autologous bone, because FFB allows bone regeneration thanks to its osteoinductive and osteoconductive properties. The purpose of this work is to describe the surgical-implant-prosthetic treatment of two complex cases using FFB. In particular, fresh frozen homologous bone grafts were used to correct the severe atrophy of the maxilla, and, then, once the graft integration was obtained, implant therapy was performed and implants placed in native bone were immediately loaded.

Research paper thumbnail of Evaluation of the Success Criteria for Zirconia Dental Implants: A Four-Year Clinical and Radiological Study

International Journal of Dentistry, 2013

Objectives. The aim was to evaluate survival and success rates, soft tissue health, and radiograp... more Objectives. The aim was to evaluate survival and success rates, soft tissue health, and radiographic marginal bone loss (MBL) of zirconia implants placed in the esthetic and posterior areas of the jaws and in association with multiple or single implant restorations after at least 6 months of definitive restoration.Material and Methods. 35 one-piece zirconium implants were utilized for single or partially edentulous ridges rehabilitation. All implants received immediate temporary restorations and six months after surgery were definitively restored. Every 6 months after implant placement, a clinical-radiographic evaluation was performed. For each radiograph, the measurements of MBL were calculated.Results. The results showed that the mean MBL at 48-month followup was 1.631 mm. The mean MBL during the first year of loading was not more significant for implants placed in the first molar regions than for those positioned in other areas. Moreover, no differences in marginal bone level cha...

Research paper thumbnail of Rare Bilateral Nasopalatine Duct Cysts: A Case Report

The Open Dentistry Journal, 2010

The nasopalatine duct cyst (NPDC) is the most common of the non-odontogenic cyst of the jaws. Thi... more The nasopalatine duct cyst (NPDC) is the most common of the non-odontogenic cyst of the jaws. This cysts are usually central or unilateral with no prevalence of side occurrence. The NPDC is the most frequent developmental, nonodontogenic cyst of the jaws. This cyst originates from epithelial remnants from the nasopalatine duct. The cells could be activated spontaneously during life, or are eventually stimulated by the irritating action of various agents (infection, etc.). Generally, patients present without clinical signs and symptoms. Therefore, the tentative diagnosis "nasopalatine duct cyst" is often based on a coincidental radiological finding on a routine panoramic view or occlusal radiograph. The definite diagnosis should be based on clinical, radiological and above all histopathologic findings. The therapy of nasopalatine duct cysts consists of an enucleation of the cystic tissue, only in rare cases a marsupialization needs to be performed. This report describes the...

Research paper thumbnail of Multiple teeth replacement with endosseous one-piece yttrium-stabilized zirconia dental implants

Medicina Oral Patología Oral y Cirugia Bucal, 2012

Objectives: The purpose of this study is to clinically and radiographically evaluate survival and... more Objectives: The purpose of this study is to clinically and radiographically evaluate survival and success rate of multiple zirconia dental implants positioned in each patient during a follow-up period of at least 12 months up to 48 months. Study Design: Eight patients were treated for multiple edentulism with 29 zirconia dental implants. All implants received immediate temporary restorations and 6 months after surgery were definitively restored. 6 months to 4 years after implant insertion, a clinical-radiographic evaluation was performed in order to estimate peri-implant tissues health and peri-implant marginal bone loss. Results: Survival rate within follow-up period was therefore 100%. The average marginal bone loss (MBL) from baseline to 6 months was +1.375±0.388 mm; from 6 months to 1 year was +0.22±0.598 mm; from 1 year to 2 years was-0.368±0.387 mm; from 2 years to 3 years was-0.0669±0.425 mm; from 3 years to 4 years +0.048±0.262 mm. The mean marginal bone loss at 4 years from the implants insertion was +1.208 mm. Conclusions: According to several studies, when using a radiographic criterion for implant success, marginal bone loss below 0.9-1.6 mm during the first year in function can be considered acceptable. In our work, radiographic measurements of MBL showed values not exceeding 1.6 mm during the first year of loading and also 1 year up to 4 years after surgery further marginal bone loss was minimal and not significant. This peri-implant bone preservation may be associated to the absence of micro-gap between fixture and abutment since zirconia dental implants are one-piece implant. Moreover, zirconia is characterized by high biocompatibility and it accumulates significantly fewer bacteria than titanium.

Research paper thumbnail of Classification of Sinus Membrane Perforations Occurring During Transcrestal Sinus Floor Elevation and Related Treatment

The International Journal of Periodontics & Restorative Dentistry, 2020

Research paper thumbnail of Crestal sinus lift by using a mini-invasive procedure: a case series

Minerva stomatologica, 2016

The aim of this study was to present a case series treated with an atraumatic procedure for maxil... more The aim of this study was to present a case series treated with an atraumatic procedure for maxillary sinus lift by crestal approach. This technique avoids the use of classical osteotomes, thus decreasing complications due to percussive and vibratory forces. Three cases of partial edentulism in the distal maxillae with inadequate bone volume are treated by using SinCrest® procedure (Meta, Reggio Emilia, Italy). With the guide of surgical templates, the sinus lift was performed, and implants were placed during the same procedure. After 6 months an X-ray was taken to check the success of the operation. SinCrest® allows the operator to advance progressively, maintaining the correct axis for implant placement. The plane tip of drills prevents accidental perforations of Schneiderian mucose, and the stops, available in different lengths, avoid the overtreatment. The manual screwing of SinCrest® osteotome ensures precision during the cortical approach, while the built-in probe allows to ch...

Research paper thumbnail of TGF-beta1 and VEGF after fresh frozen bone allograft insertion in oral-maxillo-facial surgery

Histology and histopathology, 2010

Bone regeneration technique using allografts is widely used in oral surgery to repair alveolar de... more Bone regeneration technique using allografts is widely used in oral surgery to repair alveolar defects and to increase alveolar volume for endosseous implant insertions. Bone allografts promote the reabsorption and neo-synthesis of bone tissue, which are regulated by numerous cytokines, proteins and growth factors. In this study, six patients with insufficient alveolar volume for endosseous implant insertions, were treated with bone regeneration technique using Fresh Frozen Bone (FFB) allografts collected from the femoral head or the hip. Samples of bone graft collected during graft insertion surgery and biopsies collected six months later during implantology were fixed, decalcified and analyzed histomorphologically and morphometrically by haematoxylin-eosin staining. In addition, TGF-beta1 and VEGF were analyzed by immunohistochemistry. The histological analysis of FFBs showed wide areas of calcified bone organized in osteons intermingled with areas of non-calcified matrix containi...

Research paper thumbnail of Analysis of Forces Applied During Transalveolar Sinus Lift: A Preliminary Clinical Study

Implant dentistry, Jan 27, 2018

To introduce a novel modality that enables the measurement of forces applied during a transalveol... more To introduce a novel modality that enables the measurement of forces applied during a transalveolar sinus floor elevation (tSFE) and to investigate the influence of anatomical and surgical factors on the necessitated force in sinus membrane detachment. A new endosinus probe, innovated with a calibrated load cell, was used to test the forces needed to perforate ten maxillary sinuses in 5 human cadavers. The same probe was also used to detach the Schneiderian membrane from the bony floor of 21 human subjects undergoing tSFE. The force needed to cause membrane perforation in the cadaver sample was on average 3.46 ± 1.04 N. The maximum force applied in vivo to a sinus membrane without perforation was 2.01 ± 0.67 N on average. Regression analysis showed that smoking (P < 0.001), as well as 3.0 mm osteotomy (P < 0.001), was significantly correlated to increased forces during membrane detachment. The maximum force needed to detach the membrane was found to be, on average, lower than ...

Research paper thumbnail of Microbiological analysis of bacterial plaque on three different threads in oral surgery

Minerva stomatologica, 2017

Suture is the final act of most oral surgery procedures. The quality of healing after the operati... more Suture is the final act of most oral surgery procedures. The quality of healing after the operation depends on its efficiency. Sutures must not cause inflammation - neither directly nor indirectly. The objective of this study is to compare the bacterial colonization on different suture materials after a third molar extraction. Thirty patients were randomly selected among people going under third molar extraction; they were divided into 3 groups and one suture type was used on each group. After 7 days distal stitches were removed by a single operator, placed in physiologic solution and analyzed after 2 or 3 hours. Patients followed the same postsurgical protocols; materials used were: Ethicon Silk® 4/0, B. Braun Dafilon® 4/0, and B. Braun Safil® 4/0. The amount of cocci and bacilli on the sutures analyzed shows that silk (Ethicon Silk) is the higher level of retention material where monofilament (B. Braun Dafilon) is the lower. There is a difference between monofilament and polyglyco...

Research paper thumbnail of Incidence and characteristics of mandibular accessory canals: A radiographic investigation

Journal of Investigative and Clinical Dentistry, 2017

Aim: The aim of the present study was to explore, through tridimensional reconstructions of cone-... more Aim: The aim of the present study was to explore, through tridimensional reconstructions of cone-beam computed tomography (CBCT) scans, the presence and the characteristics of mandibular accessory canals. Methods: For each included participant, the presence of accessory canals was recorded. The diameter of the canal, as well as the distance between the canal walls and the walls of the mandibular bone (lingual, buccal, cranial and caudal), were measured and recorded. Results: Mandibular accessory canals could be found in 8.8% of participants. Retromolar canals were the most frequently found accessory mandibular canals. Conclusions: Accessory mandibular canals were found in a relatively high number of participants through the examination of CBCT scans and tridimensional reconstruction. The presence of such structures should be considered cautiously when planning and performing surgical interventions in mandibular area.

Research paper thumbnail of CBCT evaluation of the tridimensional relationship between impacted lower third molar and the inferior alveolar nerve position

Minerva stomatologica, 2017

The aim of this study is to evaluate if the statistical significant relations between the measure... more The aim of this study is to evaluate if the statistical significant relations between the measures taken exists or not and to show how the 3D reconstruction could be help the oral surgeon in all those instances in which it may have a direct impact on the planning of the surgical steps. Thanks to use of NobelClinician™ Software it was possible to analyze 200 mandibular tomography computerized, random selected, and create a 3D reconstruction of mandibular bone, point out dental structure of wisdom tooth and the way of IAN. Statistical analysis was performed using the Statistical Package for Social Sciences. One way ANOVA test was used to measure the association between each independent variable and the outcome variable, followed by the post-hoc least significant difference (LSD) test for intergroup differences. Two independent variables were significant predictors for risk to have the distance 0 mm from IAN to apex: "Ramus relationship/space available" and "depth"....

Research paper thumbnail of Sinus presurgical evaluation: a literature review and a new classification proposal

Minerva stomatologica, Jan 15, 2017

Presurgical evaluation with cone beam computed tomography (CBCT) or computed tomography (CT) has ... more Presurgical evaluation with cone beam computed tomography (CBCT) or computed tomography (CT) has become an essential tool for diagnosis and surgical planning, including maxillary sinus floor elevation. Before performing a sinus lift, the clinician's attention should not be only directed to the patency of the ostium through CBCT or CT, because many anatomical features could influence the surgical approach of sinus floor elevation. The goal of this article was to facilitate the communication between clinicians regarding the type of maxillary sinus, encourage in-depth analysis prior to surgery and reduce the risk of complications due to possible underestimation of important parameters. An electronic search was conducted in Pubmed, Embase, Medline and Scopus, matching the following keywords: "sinus lift", "CBCT", "CT", "presurgical" and "evaluation". Clinical Oral Implant Research, Implant Dentistry, International Journal of Periodon...

Research paper thumbnail of Infection Related Inferior Alveolar Nerve Paresthesia in the Lower Premolar Teeth

Case Reports in Dentistry, 2016

Introduction. The aim of this paper was to describe two cases of IAN infection-induced paresthesi... more Introduction. The aim of this paper was to describe two cases of IAN infection-induced paresthesia and to discuss the most appropriate treatment solutions.Methods. For two patients, periapical lesions that induced IAN paresthesia were revealed. In the first case, the tooth was previously endodontically treated, whereas in the second case the lesion was due to pulp necrosis.Results. For the first patient, a progressive healing was observed only after the tooth extraction. In the second patient, the paresthesia had resolved after endodontic treatment.Conclusions. The endodontic-related paresthesia is a rare complication that can be the result of a combination of etiopathogenic mechanisms such as mechanical pressure on the nerve fibers due to the expanding infectious process and the production of microbial toxins. Paresthesia resulting from periapical lesions usually subsides through elimination of infection by root canal treatment. However, if there are no signs of enhancement, the im...

Research paper thumbnail of Zirconia Implants in Esthetic Areas: 4-Year Follow-Up Evaluation Study

International Journal of Dentistry, 2015

Objectives.The aim is to evaluate the survival and success rates, as well as the marginal bone lo... more Objectives.The aim is to evaluate the survival and success rates, as well as the marginal bone loss (MBL) and periodontal indexes of zirconia implants positioned in the esthetic jaw areas.Materials and Method.13 patients were selected and 20 one-piece zirconia implants were used for the rehabilitation of single tooth or partially edentulous ridge in the esthetic jaw areas. Six months after surgery and then once a year, a clinical-radiographic evaluation was performed in order to estimate peri-implant tissue health and marginal bone loss.Results.The survival and success rates were 100%. The average marginal bone loss from baseline to 48 months after surgery was +2.1 mm. Four years after surgery, the median and the mode for visible Plaque Index and Bleeding On Probing resulted 1 whereas Probing Pocket Depth amounted to 3 mm (SD = ±0.49 mm).Conclusion.One-piece zirconia dental implants are characterized by high biocompatibility, low plaque adhesion, and absence of microgap that can be ...

Research paper thumbnail of Radiotrasparenza dell’angolo mandibolare. Due casi di lacuna di Stafne

Dental Cadmos, 2011

ObjectivesTo describe two Stafne bone cavity cases, focusing on instrumental investigations besid... more ObjectivesTo describe two Stafne bone cavity cases, focusing on instrumental investigations besides pathogenesis, in order to reach correct differential diagnosis and therapy.

Research paper thumbnail of Cisti del dotto nasopalatino di notevoli dimensioni: presentazione di un caso clinico e follow-up

Dental Cadmos, 2011

ABSTRACT Objectives The main objective of this article is to describe the surgical approach used ... more ABSTRACT Objectives The main objective of this article is to describe the surgical approach used for the enucleation of an unusually large nasopalatine cyst and the long-term results obtained.

Research paper thumbnail of Clinical evaluation of zirconium dental implants placed in esthetic areas: a case series study

The European journal of esthetic dentistry : official journal of the European Academy of Esthetic Dentistry, 2013

The purpose of this study was to evaluate the esthetic result of monophasic zirconium dental impl... more The purpose of this study was to evaluate the esthetic result of monophasic zirconium dental implants, placed in the highly esthetic areas of the jaws. In this case series the results of 12 monophasic zirconium dental implants placed in highly esthetic areas of 8 patients (6 male and 2 female). For each implant the Pink Esthetic Score (PES) and the White Esthetic Score (WES) were evaluated. All implants were inserted in fresh postextraction sites. The esthetic parameters PES/ WES has given a total average value of 15.5 ± 1.5. Analyzing the two indices individually, the PES has given a value equal to 7.5 ± 1 and the WES has given a value equal to 8 ± 1.13. Both values obtained indicate the achievement of an absolutely satisfactory esthetic result. Within the limits of this study, the zirconium dental implants seems to give excellent results with regard to the esthetic result and for the maintenance of peri-implant soft tissues.

Research paper thumbnail of Behavior of endosseous one-piece yttrium stabilized zirconia dental implants placed in posterior areas

Minerva stomatologica

Considering that zirconia dental implants are indicated for the rehabilitation of highly esthetic... more Considering that zirconia dental implants are indicated for the rehabilitation of highly esthetic areas, the aim of this work was to investigate the functional behavior of these implants positioned in the posterior regions of the jaws. The study included 6 patients with 14 zirconia implants positioned in posterior (molar) areas of the jaws. Immediately after surgery, all implants were restored with temporary crowns or bridges. Clinical radiographic evaluation was performed 6 months after surgery and subsequently every year. At these follow-up visits, periodontal indexes were recorded and peri-apical radiographs were taken in order to calculate marginal bone loss. The success and survival rates were 100%. The modified bleeding index (mBI) and modified plaque index (mPLI) were respectively equal to 0.57±0.51 and 0.29 ± 0.47 at 4-year follow-up. The overall mean probing depth of the implants was 3.13±0.87 mm. The mean marginal bone loss was +0.665 mm 4 years after surgery. Considering ...

Research paper thumbnail of An uncommon clinical feature of IAN injury after third molar removal: a delayed paresthesia case series and literature review

Quintessence international (Berlin, Germany : 1985), 2012

After an inferior alveolar nerve (IAN) injury, the onset of altered sensation usually begins imme... more After an inferior alveolar nerve (IAN) injury, the onset of altered sensation usually begins immediately after surgery. However, it sometimes begins after several days, which is referred to as delayed paresthesia. The authors considered three different etiologies that likely produce inflammation along the nerve trunk and cause delayed paresthesia: compression of the clot, fibrous reorganization of the clot, and nerve trauma caused by bone fragments during clot organization. The aim of this article was to evaluate the etiology of IAN delayed paresthesia, analyze the literature, present a case series related to three different causes of this pathology, and compare delayed paresthesia with the classic immediate symptomatic paresthesia.

Research paper thumbnail of Esthetic Rehabilitation of a Severely Compromised Anterior Area: Combined Periodontal and Restorative Approach

Case Reports in Dentistry, 2014

The complete oral rehabilitation of patients demanding a beautiful and attractive smile involves ... more The complete oral rehabilitation of patients demanding a beautiful and attractive smile involves a multidisciplinary approach that includes the change of both the morphological aspect of the teeth and the architecture of gum tissues. This clinical report describes a successful interdisciplinary approach for the treatment of an esthetically compromised dentition. In a first phase, the periodontal plastic surgery was performed for root coverage and, in particular, it was decided for the execution of a coronally advanced flap for the treatment of multiple recession defects. Once complete healing of soft tissues was obtained, six lithium disilicate veneers were placed over the anterior maxillary teeth. Lithium disilicate is a glass-based ceramic which presents excellent aesthetics and allows the passage of light without creating unnatural reflections. This feature has made it possible to recreate a natural aspect of teeth that in combination with the harmonic architecture of soft tissue...

Research paper thumbnail of Treatment of the Atrophic Upper Jaw: Rehabilitation of Two Complex Cases

Case Reports in Dentistry, 2013

In reconstructive surgery, the fresh frozen homologous bone (FFB) represents a valid alternative ... more In reconstructive surgery, the fresh frozen homologous bone (FFB) represents a valid alternative to the autologous bone, because FFB allows bone regeneration thanks to its osteoinductive and osteoconductive properties. The purpose of this work is to describe the surgical-implant-prosthetic treatment of two complex cases using FFB. In particular, fresh frozen homologous bone grafts were used to correct the severe atrophy of the maxilla, and, then, once the graft integration was obtained, implant therapy was performed and implants placed in native bone were immediately loaded.

Research paper thumbnail of Evaluation of the Success Criteria for Zirconia Dental Implants: A Four-Year Clinical and Radiological Study

International Journal of Dentistry, 2013

Objectives. The aim was to evaluate survival and success rates, soft tissue health, and radiograp... more Objectives. The aim was to evaluate survival and success rates, soft tissue health, and radiographic marginal bone loss (MBL) of zirconia implants placed in the esthetic and posterior areas of the jaws and in association with multiple or single implant restorations after at least 6 months of definitive restoration.Material and Methods. 35 one-piece zirconium implants were utilized for single or partially edentulous ridges rehabilitation. All implants received immediate temporary restorations and six months after surgery were definitively restored. Every 6 months after implant placement, a clinical-radiographic evaluation was performed. For each radiograph, the measurements of MBL were calculated.Results. The results showed that the mean MBL at 48-month followup was 1.631 mm. The mean MBL during the first year of loading was not more significant for implants placed in the first molar regions than for those positioned in other areas. Moreover, no differences in marginal bone level cha...

Research paper thumbnail of Rare Bilateral Nasopalatine Duct Cysts: A Case Report

The Open Dentistry Journal, 2010

The nasopalatine duct cyst (NPDC) is the most common of the non-odontogenic cyst of the jaws. Thi... more The nasopalatine duct cyst (NPDC) is the most common of the non-odontogenic cyst of the jaws. This cysts are usually central or unilateral with no prevalence of side occurrence. The NPDC is the most frequent developmental, nonodontogenic cyst of the jaws. This cyst originates from epithelial remnants from the nasopalatine duct. The cells could be activated spontaneously during life, or are eventually stimulated by the irritating action of various agents (infection, etc.). Generally, patients present without clinical signs and symptoms. Therefore, the tentative diagnosis "nasopalatine duct cyst" is often based on a coincidental radiological finding on a routine panoramic view or occlusal radiograph. The definite diagnosis should be based on clinical, radiological and above all histopathologic findings. The therapy of nasopalatine duct cysts consists of an enucleation of the cystic tissue, only in rare cases a marsupialization needs to be performed. This report describes the...

Research paper thumbnail of Multiple teeth replacement with endosseous one-piece yttrium-stabilized zirconia dental implants

Medicina Oral Patología Oral y Cirugia Bucal, 2012

Objectives: The purpose of this study is to clinically and radiographically evaluate survival and... more Objectives: The purpose of this study is to clinically and radiographically evaluate survival and success rate of multiple zirconia dental implants positioned in each patient during a follow-up period of at least 12 months up to 48 months. Study Design: Eight patients were treated for multiple edentulism with 29 zirconia dental implants. All implants received immediate temporary restorations and 6 months after surgery were definitively restored. 6 months to 4 years after implant insertion, a clinical-radiographic evaluation was performed in order to estimate peri-implant tissues health and peri-implant marginal bone loss. Results: Survival rate within follow-up period was therefore 100%. The average marginal bone loss (MBL) from baseline to 6 months was +1.375±0.388 mm; from 6 months to 1 year was +0.22±0.598 mm; from 1 year to 2 years was-0.368±0.387 mm; from 2 years to 3 years was-0.0669±0.425 mm; from 3 years to 4 years +0.048±0.262 mm. The mean marginal bone loss at 4 years from the implants insertion was +1.208 mm. Conclusions: According to several studies, when using a radiographic criterion for implant success, marginal bone loss below 0.9-1.6 mm during the first year in function can be considered acceptable. In our work, radiographic measurements of MBL showed values not exceeding 1.6 mm during the first year of loading and also 1 year up to 4 years after surgery further marginal bone loss was minimal and not significant. This peri-implant bone preservation may be associated to the absence of micro-gap between fixture and abutment since zirconia dental implants are one-piece implant. Moreover, zirconia is characterized by high biocompatibility and it accumulates significantly fewer bacteria than titanium.

Research paper thumbnail of Classification of Sinus Membrane Perforations Occurring During Transcrestal Sinus Floor Elevation and Related Treatment

The International Journal of Periodontics & Restorative Dentistry, 2020

Research paper thumbnail of Crestal sinus lift by using a mini-invasive procedure: a case series

Minerva stomatologica, 2016

The aim of this study was to present a case series treated with an atraumatic procedure for maxil... more The aim of this study was to present a case series treated with an atraumatic procedure for maxillary sinus lift by crestal approach. This technique avoids the use of classical osteotomes, thus decreasing complications due to percussive and vibratory forces. Three cases of partial edentulism in the distal maxillae with inadequate bone volume are treated by using SinCrest® procedure (Meta, Reggio Emilia, Italy). With the guide of surgical templates, the sinus lift was performed, and implants were placed during the same procedure. After 6 months an X-ray was taken to check the success of the operation. SinCrest® allows the operator to advance progressively, maintaining the correct axis for implant placement. The plane tip of drills prevents accidental perforations of Schneiderian mucose, and the stops, available in different lengths, avoid the overtreatment. The manual screwing of SinCrest® osteotome ensures precision during the cortical approach, while the built-in probe allows to ch...