Borhane Mahjoub - Academia.edu (original) (raw)

Papers by Borhane Mahjoub

The circularity of the bioeconomy is related to the sustainable valorisation of bioresources. Org... more The circularity of the bioeconomy is related to the sustainable valorisation of bioresources. Organic wastes are increasingly becoming a valuable resource and have the potential to significantly spur the transition towards a sustainable and circular bioeconomy. Important progress has recently been realized to produce new value-added products and energy from different kinds of organic waste feedstock. There is still a large potential in exploitation of waste and side streams in specialised high value circles. To accomplish this bioeconomical circularity, larger research and innovation efforts are still required and more cross-sectoral collaboration is needed, both on the local, regional and international levels. The entire economy must be involved, and a wide range of policy instruments must be used for the transition process, including systemic change, as well as a better regulation and governance.

HAL (Le Centre pour la Communication Scientifique Directe), 2016

La population générale est exposée aux HAP principalement par l'ingestion de nourriture (en ... more La population générale est exposée aux HAP principalement par l'ingestion de nourriture (en particulier les viandes ou aliments fumés, frits ou cuits sur charbon de bois) et par l'inhalation de fumée de tabac 5,6 . Les patients psoriasiques se traitant avec des onguents ou des ...

Les stations d'épuration (STEPs) sont des sources majeures de contaminants des ressources en eaux... more Les stations d'épuration (STEPs) sont des sources majeures de contaminants des ressources en eaux et de l'environnement. Les hydrocarbures aromatiques polycycliques (HAPs) sont persistants, bioaccumulables, toxiques, cancérogènes, mutagènes, et certains sont dotés d'un pouvoir perturbateur endocrinien. La présence et la distribution des 16 HAPs de l'USEPA ont été étudiées dans des ressources en eau utilisées pour l'irrigation en Tunisie (des eaux usées traitées (EUT), des eaux de surface et des eaux souterraines). L'analyse a montré que la somme des HAPs varie entre 0,47 et 2,47 µg/l dans les EUT, entre 0,30 et 3,93 µg/l dans les eaux de surface et entre 0,12 et 2,80 µg/l dans les eaux souterraines. Les concentrations des HAPs dans les ressources en eau a montré une distribution temporelle et spatiale en faveur de la saison sèche et des points de rejets des effluents des EUT.

L'ensemble des pays industrialises comptent sur leurs territoires de nombreux sites potentiel... more L'ensemble des pays industrialises comptent sur leurs territoires de nombreux sites potentiellement pollues par le goudron de houille. A long terme, la mobilite des polluants dans le sol est principalement controlee par la dissolution dans l'eau des composes du goudron ainsi que par les phenomenes d'adsorption 1 desorption et de biodegradation de ces polluants dans le sol. Trois polluants modeles ainsi que plusieurs fractions de sols et des sols de reference ont ete selectionnes lors de notre etude qui s'est deroulee en 2 principales etapes: - Etude des equilibres et des cinetiques de partage des polluants organiques entre le goudron de houille et l'eau -Etude de l'adsorption et de la desorption des polluants organiques dans le sol, en considerant les cinetiques de transfert a court et a long terme. Les resultats experimentaux nous montrent que le goudron de houille ne possede pas un comportement ideal decrit par la loi de Raoult. Les principaux mecanismes de transfert goudron/eau identifies sont la solubilisation quasi-instantanee des polluants proches de l'interface PLA/eau, et la diffusion lente des polluants au sein de la PLNA et a l'interface. Les resultats montrent de plus que plusieurs facteurs peuvent modifier la vitesse et l'ampleur du relargage (temperature, pH, force ionique, vieillissement de l'interface. . . ). Les resultats de la seconde partie de l'etude montrent une diminution de la mobilite des polluants avec l'augmentation de la duree de contact polluant/sol. Nous avons de plus observe que la succession des cycles de gel/degel tendait a limiter l'effet du vieillissement. La retention a cinetique lente du polluant par le sol ou l'argile est tres probablement due a la lente diffusion moleculaire au sein des micropores des agregats ou bien au sein de la matiere organique du sol

Water Research, Oct 1, 2000

ÐOn some abandoned manufactured-gas plant sites the presence of a particular non-aqueous phase li... more ÐOn some abandoned manufactured-gas plant sites the presence of a particular non-aqueous phase liquid (NAPL), namely coal tar, represents a potential source of groundwater pollution. The aim of this study was to characterise the phase partition of aromatic pollutants between coal tar and water. Batch trials have been carried out in order to evaluate the state of phase partition equilibrium of pollutants between coal tar and water, under variable experimental conditions (temperature, pH, ionic strength, coal tar composition). The experimental results clearly show that coal tar cannot be considered as an ideal solution with regards to phase partition of pollutants with water. The main identi®ed mechanisms of phase partition are the quasi instantaneous solubilization of pollutants near the coal tar/water interphase, and the diusion of pollutants within the organic phase or at the interphase which controls the transfer kinetics of pollutants towards the aqueous phase. The dissolution kinetics experimentally observed were therefore correlated to a diusional model of mass transfer. The formation of a ®lm which increased resistance to mass transfer was also observed at the coal tar/water interphase. This ageing phenomenon of the coal tar/water interphase was found to be an important aspect which can have a signi®cant in¯uence on the long term fate of coal tar in soils or subsoils, as well as on soil remediation techniques.

Elsevier eBooks, 2021

Abstract Along with water scarcity and the new risks related to climate change, pollution is a ma... more Abstract Along with water scarcity and the new risks related to climate change, pollution is a major issue affecting this vital resource globally. To face the challenge of treating large volumes of pollutants-loaded municipal wastewaters and industrial effluents, researchers have been investigating the application of different biological, physical, and (electro)chemical water treatment technologies. In this context, the application of adsorption for the removal of toxic or undesirable compounds from (waste)water is widely recognized as a versatile decontamination procedure, which is able to deal with a wide range of pollutants under various process configurations and operating conditions. In this chapter, relevant and recent research investigations conducted in North African countries (Libya, Tunisia, and Morocco) are presented and discussed, including diverse sorbents, adsorption systems, and targeted pollutants. Overall the main objective of this chapter is to showcase the current situation and prospects for the production and utilization of conventional and advanced sorbents for water depollution in North Africa.

Journal of Hazardous Materials, May 20, 2006

Herein, an experimental study coupled with a model in order to assess the non-equilibrium and mul... more Herein, an experimental study coupled with a model in order to assess the non-equilibrium and multi-compound dissolution behaviour of a coal tar containing PAHs and phenols into water, is presented. For this aim, two experimental studies has been carried out: (1) coal tar-water partition equilibrium and (2) dissolution dynamics of coal tar under controlled hydrodynamic conditions in percolation columns packed with glass beads. The dissolution amount of the three target constituents (i.e. phenol, naphthalene and phenanthrene) was monitored by UV detection. The dissolution behaviour was modelled using a predictive fraction approach. The partition coefficients have been estimated from experimental data and the obtained results show that the partition coefficient of each constituent between the aqueous phase and the tar depends on the activities of the constituent in both phases and cannot be estimated only from the solubility of the pure compound in water. The non-equilibrium dissolution model was established, applied for the experimental conditions and validated for three target compounds adjusting the effective interfacial area between tar and water. This parameter is specific of the experimental setup. The global behaviour of coal tar has been modelled taking into account four categories of compounds according to their water solubility and volatilities. The mass transfer parameters have been estimated using available correlations. The results of this paper indicate that a model based on component fractions can be used to assess the non-equilibrium dissolution behaviour of a coal tar.

Journal of Hazardous Materials, Jul 1, 2007

The effects of aging on the extractability of naphthalene and phenanthrene were investigated usin... more The effects of aging on the extractability of naphthalene and phenanthrene were investigated using laboratory batch assays. Experiments have been conducted with three soil matrices: a silty clay and two soils with different organic contents. Aging was conducted under abiotic conditions in water saturated and nonsaturated conditions, under a constant temperature (20 • C). The mobility of sorbed contaminants was evaluated through successive extractions in water, methanol, butanol and dichloromethane. Experimental results showed a reduction of the extractability of both naphthalene and phenanthrene with increasing aging times. The observed effects of aging might be related to slow diffusion of naphthalene and phenanthrene in sorbent microporosity and/or organic phases and possible evolutions of pollutant-sorbent interactions.

International Journal of Environment and Waste Management, 2014

ABSTRACT Packed columns were prepared using Posidonia oceanica fibres as adsorbent for the remova... more ABSTRACT Packed columns were prepared using Posidonia oceanica fibres as adsorbent for the removal of a direct dye, Congo red (CR), from aqueous solution. The effects of flow rate, concentration of CR, pH solution and bed depth on breakthrough curves were investigated. The experimental results showed that the breakthrough time decreased with the increase of flow rate, influent concentration and the decrease of bed depth. The amount of sorbed dye decreased by increasing the flow rate and increased by increasing the dye concentration and bed height. The removal of CR by raw Posidonia fibres reached 80% with a dye concentration of 10 mg.l−1 at the flow rate of 0.47 ml.min−1 and at pH 6.5. Thomas, Yoon-Nelson, Adams-Bohart and bed depth/service time analysis (BDST) models were successfully used to analyse experimental data, to predict the breakthrough curves and to determine the characteristic parameters of the column useful for the process design.

Environnement, ingénierie & développement, 2009

HAL is a multidisciplinary open access archive for the deposit and dissemination of scientific re... more HAL is a multidisciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L'archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d'enseignement et de recherche français ou étrangers, des laboratoires publics ou privés. Distributed under a Creative Commons Attribution| 4.0 International License Élimination du chrome hexavalent des solutions aqueuses par adsorption sur feuilles brutes de Posidonia oceanica (L.) : cinétiques, équilibres et modélisation

International Journal of Biological Macromolecules, Jul 1, 2018

Mounting evidence indicates soluble Aβ 42 oligomers as the most toxic species causing neuronal de... more Mounting evidence indicates soluble Aβ 42 oligomers as the most toxic species causing neuronal death which leads to the onset and progression of Alzheimer disease (AD). Recently, it has been found that neurotoxic Aβ 42 oligomers grow from monomeric species or arise following secondary nucleation by preformed mature fibrils. Thus, the use of natural compounds such as polyphenols to hinder the growth or to remodel Aβ 42 fibrils is one of the most promising strategies for AD treatment. In our previous study, we showed that 1, 2, 4trihydroxynaphthalene-2-O-β-D-glucopyranoside (THNG) inhibits Aβ 42 aggregation during the early steps of the aggregation process, inhibits its conformational change to a β-sheet-rich structure, decreases its polymerization, inhibits its fibrillogenisis and reduces oxidative stress and aggregate cytotoxicity. Here, we used different spectroscopic and cell culture methods to check the effect of THNG on fibrils disaggregation. We showed that THNG binds to mature Aβ 42 fibrils, rearrange their secondary structure, and remodels them into non-amyloid, less toxic, species by inhibiting their interaction with the plasma membrane. Our findings reveal that THNG is a good agent to remodel amyloid fibrils and could be used as a starting molecular scaffold to design new anti-AD drugs.

Biofactors, Mar 26, 2018

Presently, misfolding and aggregation of amyloid-β (Aβ ) are considered early events in Alzheimer... more Presently, misfolding and aggregation of amyloid-β (Aβ ) are considered early events in Alzheimer's disease (AD) pathogenesis. The use of natural products to inhibit the aggregation process and to protect cells from cytotoxicity of early aggregate grown at the onset of the aggregation path is one of the promising strategies against AD. Recently, we have purified a new powerful antioxidant and inhibitor of Aβ aggregation from the leaves of Lawsonia inermis. The new compound was identified as a new Lawsoniaside; 1,2,4-trihydroxynaphthalene-2-O-β-D-glucopyranoside (THNG). Herein, we show that THNG interferes with Aβ aggregation, inhibits its conformational change to a β-sheet-rich structure, decreases its polymerization into large fibrillar species, reduces oxidative stress, and aggregate cytotoxicity. These results indicate that THNG has great potential as a neuroprotective and therapeutic agent against AD. © 2018 BioFactors, 44(3):272-280, 2018.

Natural Product Research, Dec 29, 2017

Mounting evidence indicates free radicals as toxic species causing damage to human cells leading ... more Mounting evidence indicates free radicals as toxic species causing damage to human cells leading to the pathogenesis of many diseases such as neurodegenerative disease. Plant derived antioxidants are considered as promising strategy to prevent free radical toxicity. In this study, the crude extract (CE), 50%MeOH, Petroleum Ether (PE) and Ethyl acetate (EA) fractions of Lawsonia inermis leaves were investigated for their antioxidant activity and their ability to counteract amyloid-β 42 (Aβ 42) aggregation. Elution of the most bioactive fraction (EA) on silica gel column chromatography led to six sub-fractions. The most active sub-fraction (1) was further resolved on silica gel column chromatography. A new compound with powerful antioxidant and anti-Aβ 42 aggregation properties was purified and characterized by spectroscopic methods as 1,2,4-trihydroxynaphthalene-2-O-β-D-glucopyranoside (THNG). This finding suggests that the antioxidant and anti-Aβ 42 aggregation activities of L. inermis leaves are strongly correlated to this compound.

Clean-soil Air Water, Mar 17, 2017

The emergence of new kinds of pollutants including pharmaceuticals drugs, endocrine disrupting co... more The emergence of new kinds of pollutants including pharmaceuticals drugs, endocrine disrupting compounds, radionuclides, flame retardants, surfactants and microbial toxins, to name a few, is posing new and serious challenges to the conventional wastewater treatment techniques, to the extent that the treatment plants are becoming indirect source of pollution. Thus, in order to meet these new environmental threats, tremendous research and development efforts were and are being made to optimize the efficiency of several remediation techniques. In this review, recent and valuable research works will be presented and discussed concerning the remediation of emerging pollutants in contaminated wastewaters and aquatic environments through biomass-based technologies, including bio-adsorption using both terrestrial and marine bioresources and agro-industrial wastes along with derived activated carbons. Phytoremediation, microbial remediation using bacteria, fungi, yeasts was also reported, in addition to some interesting combination scenarios such as biodegradtion/filtration, adsorption/biodegradation and adsorption/ozonation. Eco-friendliness, efficiency, cost-effectiveness were the main criteria of choice among the rich literature, in order to prove that renewable biomass and its derived products could be the "sustainable core" for single or hybrid water treatment techniques, targeting emerging pollutants.

RSC green chemistry series, 2013

Degradation and pollution of soil and water, the most important natural resources sustaining terr... more Degradation and pollution of soil and water, the most important natural resources sustaining terrestrial life, can provoke disastrous consequences for the environment and, therefore, on human health and food security. Utilising plants for soil decontamination is a practical, cost-effective and in many cases an urgent option. Indeed, plants with their innate ability to degrade organic compounds or accumulate heavy metals are already being investigated by phytoremediation research teams. Unique remediation features possessed by plants are readily illustrated by the three common remediation strategies to treat contaminated soil: immobilisation, removal and destruction. Phytoremediation has become a well-established, multifaceted technology capitalising on four main aspects of phytoremediation: phytostabilisation, phytodegradation, phytovolatilisation and phytoextraction. Successful treatment of soils with mixed pollutants requires a combination of plant species with appropriate remediation properties and the inclusion of plant species hosting rhizosphere communities active against specific contaminants. Thus, the major contribution that has emerged from the field of phytoremediation is the biosystem-based approach for soil remediation through joint actions of several different organisms functioning in union or in sequence, with the central role played by plants. Knowledge of fundamental properties, along with consistent endeavour in the research and development field, should further enhance the place of phytoremediation in any sustainable soil treatment strategy.

Current opinion in green and sustainable chemistry, Oct 1, 2020

Abstract The circularity of the bioeconomy is related to the sustainable valorisation of bioresou... more Abstract The circularity of the bioeconomy is related to the sustainable valorisation of bioresources. Organic wastes (OW) are increasingly becoming a valuable resource and have the potential to significantly spur the transition towards a sustainable and circular bioeconomy. Important progress has recently been realized to produce new value-added products and energy from different kinds of OW feedstock. There is still a large potential in exploitation of waste and side streams in specialised high value circles. To accomplish this bioeconomical circularity, larger research and innovation efforts are still required and more cross-sectoral collaboration is needed, both on the local, regional and international levels. The entire economy must be involved and a wide range of policy instruments must be employed for the transition process, including systemic change as well as a better regulation and governance.

Sorbents Materials for Controlling Environmental Pollution

CLEAN - Soil, Air, Water, 2017