Brian Cohn - Academia.edu (original) (raw)

Papers by Brian Cohn

Research paper thumbnail of Does Intravascular Temperature Management Improve Outcomes Compared With Surface Cooling in Comatose Adults After Cardiac Arrest?

Annals of Emergency Medicine, 2021

TAKE-HOME MESSAGE Although intravascular temperature management does not improve survival compare... more TAKE-HOME MESSAGE Although intravascular temperature management does not improve survival compared with surfacecooling methods in post-cardiac arrest patients, it may improve neurologic outcomes.

Research paper thumbnail of Does Albumin Infusion Reduce Renal Impairment and Mortality in Patients With Spontaneous Bacterial Peritonitis?

Annals of Emergency Medicine, 2016

Albumin administration within 6 hours of diagnosis has been shown to decrease the risk of both re... more Albumin administration within 6 hours of diagnosis has been shown to decrease the risk of both renal impairment and mortality in patients with spontaneous bacterial peritonitis.

Research paper thumbnail of Can Children With Uncomplicated Acute Appendicitis Be Treated With Antibiotics Instead of an Appendectomy?

Annals of emergency medicine, Jan 25, 2015

Editor's note: Emergency physicians must often make decisions about patient management without cl... more Editor's note: Emergency physicians must often make decisions about patient management without clear-cut data of sufficient quality to support clinical guidelines or evidence-based reviews. Topics in the Best Available Evidence section must be relevant to emergency physicians, are formally peer reviewed, and must have a sufficient literature base to draw a reasonable conclusion but not such a large literature base that a traditional "evidence-based" review, meta-analysis, or systematic review can be performed. Emergency physicians must often make decisions about patient management without clear-cut data of sufficient quality to support clinical guidelines or evidence-based reviews. Topics in the Best Available Evidence section must be relevant to emergency physicians, are formally peer reviewed, and must have a sufficient literature base to draw a reasonable conclusion but not such a large literature base that a traditional "evidence-based" review, meta-analysis, or systematic review can be performed.

Research paper thumbnail of Are prophylactic antibiotics necessary for anterior nasal packing in epistaxis?

Annals of emergency medicine, 2015

Editor's Note: Emergency physicians must often make decisions about patient management without cl... more Editor's Note: Emergency physicians must often make decisions about patient management without clear-cut data of sufficient quality to support clinical guidelines or evidence-based reviews. Topics in the Best Available Evidence section must be relevant to emergency physicians, are formally peer reviewed, and must have a sufficient literature base to draw a reasonable conclusion but not such a large literature base that a traditional "evidence-based" review, meta-analysis, or systematic review can be performed. Pepper et al 8 This was a prospective before-and-after study of all subjects admitted to the otolaryngology service of a tertiary care center in

Research paper thumbnail of Can procalcitonin differentiate sepsis from systemic inflammatory response syndrome without infection?

Annals of emergency medicine, 2014

Procalcitonin must be used cautiously, in conjunction with the clinical picture, when differentia... more Procalcitonin must be used cautiously, in conjunction with the clinical picture, when differentiating sepsis from noninfectious systemic inflammatory response syndrome.

Research paper thumbnail of Can Anticoagulated Patients be Discharged Home Safely from the Emergency Department after Minor Head Injury?

The Journal of Emergency Medicine, 2014

Research paper thumbnail of Is Emergency Department Cardioversion of Recent-onset Atrial Fibrillation Safe and Effective?

The Journal of Emergency Medicine, 2013

Atrial fibrillation (AF) is a very common dysrhythmia presenting to Emergency Departments (EDs). ... more Atrial fibrillation (AF) is a very common dysrhythmia presenting to Emergency Departments (EDs). Controversy exists regarding the optimal clinical therapy for these patients, which typically focuses on rhythm rate-control and admission or cardioversion and discharge home. Is ED cardioversion of recent-onset atrial fibrillation safe, effective, and does it result in positive meaningful patient outcomes? Five observation studies with nearly 1600 ED patients with atrial fibrillation treated with either rate-control or cardioversion were reviewed and results compiled. Overall, ED cardioversion for recent-onset AF seems safe and effective, with success rates ranging from 85.5% to 97% in these studies. Although further research should seek to identify patients at low risk for thromboembolic complication, more rigorously assess patient satisfaction, and show cost savings, emergency physicians should feel comfortable using this approach in select patients. ED cardioversion for recent-onset AF seems safe and effective.

Research paper thumbnail of Does the Absence of Cardiac Activity on Ultrasonography Predict Failed Resuscitation in Cardiac Arrest?

Annals of Emergency Medicine, 2013

The absence of cardiac activity on ultrasonography does not universally lead to failure of resusc... more The absence of cardiac activity on ultrasonography does not universally lead to failure of resuscitation in cardiac arrest.

Research paper thumbnail of Does This Patient Have Acute Mesenteric Ischemia?

Annals of Emergency Medicine, 2014

Classic history, physical examination, and laboratory findings are poorly diagnostic of acute mes... more Classic history, physical examination, and laboratory findings are poorly diagnostic of acute mesenteric ischemia, whereas computed tomography (CT) angiography is a reasonable initial imaging modality.

Research paper thumbnail of Is Intravenous Acetylcysteine More Effective Than Oral Administration for the Prevention of Hepatotoxicity in Acetaminophen Overdose?

Annals of Emergency Medicine, 2014

Research paper thumbnail of Can Bedside Oculomotor (HINTS) Testing Differentiate CentralĀ From Peripheral Causes of Vertigo?

Annals of Emergency Medicine, 2014

Editor's Note: Emergency physicians must often make decisions about patient management without cl... more Editor's Note: Emergency physicians must often make decisions about patient management without clear-cut data of sufficient quality to support clinical guidelines or evidence-based reviews. Topics in the Best Available Evidence section must be relevant to emergency physicians, are formally peer reviewed, and must have a sufficient literature base to draw a reasonable conclusion but not such a large literature base that a traditional "evidence-based" review, meta-analysis, or systematic review can be performed.

Research paper thumbnail of Acute myocardial infarction from embolization of Lambl's excrescences: A case report

The American Journal of Emergency Medicine, 2021

While coronary artery embolism remains an infrequent cause of myocardial infarction (MI), it may ... more While coronary artery embolism remains an infrequent cause of myocardial infarction (MI), it may present in patients at otherwise low risk for coronary artery disease. When clinicians apply typical risk stratification in these cases, they may be led away from a full evaluation for acute coronary syndrome (ACS). A diagnosis of MI in an otherwise healthy patient should prompt consideration of embolic sources, including Lambl's excrescences (LEs), and echocardiographic evaluation may be necessary to make a final diagnosis. We present a case of LEs in an otherwise healthy 43-year-old male presenting with chest pain and elevated cardiac enzymes, and also review the cases of this rare event found in the literature.

Research paper thumbnail of Does Intravascular Temperature Management Improve Outcomes Compared With Surface Cooling in Comatose Adults After Cardiac Arrest?

Annals of Emergency Medicine, 2021

TAKE-HOME MESSAGE Although intravascular temperature management does not improve survival compare... more TAKE-HOME MESSAGE Although intravascular temperature management does not improve survival compared with surfacecooling methods in post-cardiac arrest patients, it may improve neurologic outcomes.

Research paper thumbnail of Does Albumin Infusion Reduce Renal Impairment and Mortality in Patients With Spontaneous Bacterial Peritonitis?

Annals of Emergency Medicine, 2016

Albumin administration within 6 hours of diagnosis has been shown to decrease the risk of both re... more Albumin administration within 6 hours of diagnosis has been shown to decrease the risk of both renal impairment and mortality in patients with spontaneous bacterial peritonitis.

Research paper thumbnail of Can Children With Uncomplicated Acute Appendicitis Be Treated With Antibiotics Instead of an Appendectomy?

Annals of emergency medicine, Jan 25, 2015

Editor's note: Emergency physicians must often make decisions about patient management without cl... more Editor's note: Emergency physicians must often make decisions about patient management without clear-cut data of sufficient quality to support clinical guidelines or evidence-based reviews. Topics in the Best Available Evidence section must be relevant to emergency physicians, are formally peer reviewed, and must have a sufficient literature base to draw a reasonable conclusion but not such a large literature base that a traditional "evidence-based" review, meta-analysis, or systematic review can be performed. Emergency physicians must often make decisions about patient management without clear-cut data of sufficient quality to support clinical guidelines or evidence-based reviews. Topics in the Best Available Evidence section must be relevant to emergency physicians, are formally peer reviewed, and must have a sufficient literature base to draw a reasonable conclusion but not such a large literature base that a traditional "evidence-based" review, meta-analysis, or systematic review can be performed.

Research paper thumbnail of Are prophylactic antibiotics necessary for anterior nasal packing in epistaxis?

Annals of emergency medicine, 2015

Editor's Note: Emergency physicians must often make decisions about patient management without cl... more Editor's Note: Emergency physicians must often make decisions about patient management without clear-cut data of sufficient quality to support clinical guidelines or evidence-based reviews. Topics in the Best Available Evidence section must be relevant to emergency physicians, are formally peer reviewed, and must have a sufficient literature base to draw a reasonable conclusion but not such a large literature base that a traditional "evidence-based" review, meta-analysis, or systematic review can be performed. Pepper et al 8 This was a prospective before-and-after study of all subjects admitted to the otolaryngology service of a tertiary care center in

Research paper thumbnail of Can procalcitonin differentiate sepsis from systemic inflammatory response syndrome without infection?

Annals of emergency medicine, 2014

Procalcitonin must be used cautiously, in conjunction with the clinical picture, when differentia... more Procalcitonin must be used cautiously, in conjunction with the clinical picture, when differentiating sepsis from noninfectious systemic inflammatory response syndrome.

Research paper thumbnail of Can Anticoagulated Patients be Discharged Home Safely from the Emergency Department after Minor Head Injury?

The Journal of Emergency Medicine, 2014

Research paper thumbnail of Is Emergency Department Cardioversion of Recent-onset Atrial Fibrillation Safe and Effective?

The Journal of Emergency Medicine, 2013

Atrial fibrillation (AF) is a very common dysrhythmia presenting to Emergency Departments (EDs). ... more Atrial fibrillation (AF) is a very common dysrhythmia presenting to Emergency Departments (EDs). Controversy exists regarding the optimal clinical therapy for these patients, which typically focuses on rhythm rate-control and admission or cardioversion and discharge home. Is ED cardioversion of recent-onset atrial fibrillation safe, effective, and does it result in positive meaningful patient outcomes? Five observation studies with nearly 1600 ED patients with atrial fibrillation treated with either rate-control or cardioversion were reviewed and results compiled. Overall, ED cardioversion for recent-onset AF seems safe and effective, with success rates ranging from 85.5% to 97% in these studies. Although further research should seek to identify patients at low risk for thromboembolic complication, more rigorously assess patient satisfaction, and show cost savings, emergency physicians should feel comfortable using this approach in select patients. ED cardioversion for recent-onset AF seems safe and effective.

Research paper thumbnail of Does the Absence of Cardiac Activity on Ultrasonography Predict Failed Resuscitation in Cardiac Arrest?

Annals of Emergency Medicine, 2013

The absence of cardiac activity on ultrasonography does not universally lead to failure of resusc... more The absence of cardiac activity on ultrasonography does not universally lead to failure of resuscitation in cardiac arrest.

Research paper thumbnail of Does This Patient Have Acute Mesenteric Ischemia?

Annals of Emergency Medicine, 2014

Classic history, physical examination, and laboratory findings are poorly diagnostic of acute mes... more Classic history, physical examination, and laboratory findings are poorly diagnostic of acute mesenteric ischemia, whereas computed tomography (CT) angiography is a reasonable initial imaging modality.

Research paper thumbnail of Is Intravenous Acetylcysteine More Effective Than Oral Administration for the Prevention of Hepatotoxicity in Acetaminophen Overdose?

Annals of Emergency Medicine, 2014

Research paper thumbnail of Can Bedside Oculomotor (HINTS) Testing Differentiate CentralĀ From Peripheral Causes of Vertigo?

Annals of Emergency Medicine, 2014

Editor's Note: Emergency physicians must often make decisions about patient management without cl... more Editor's Note: Emergency physicians must often make decisions about patient management without clear-cut data of sufficient quality to support clinical guidelines or evidence-based reviews. Topics in the Best Available Evidence section must be relevant to emergency physicians, are formally peer reviewed, and must have a sufficient literature base to draw a reasonable conclusion but not such a large literature base that a traditional "evidence-based" review, meta-analysis, or systematic review can be performed.

Research paper thumbnail of Acute myocardial infarction from embolization of Lambl's excrescences: A case report

The American Journal of Emergency Medicine, 2021

While coronary artery embolism remains an infrequent cause of myocardial infarction (MI), it may ... more While coronary artery embolism remains an infrequent cause of myocardial infarction (MI), it may present in patients at otherwise low risk for coronary artery disease. When clinicians apply typical risk stratification in these cases, they may be led away from a full evaluation for acute coronary syndrome (ACS). A diagnosis of MI in an otherwise healthy patient should prompt consideration of embolic sources, including Lambl's excrescences (LEs), and echocardiographic evaluation may be necessary to make a final diagnosis. We present a case of LEs in an otherwise healthy 43-year-old male presenting with chest pain and elevated cardiac enzymes, and also review the cases of this rare event found in the literature.