Brian Cox - Academia.edu (original) (raw)

Papers by Brian Cox

JNCI Monographs, 1997

This meta-analysis assesses the effectiveness of breast screening by year from the start of scree... more This meta-analysis assesses the effectiveness of breast screening by year from the start of screening for women aged 40-49 at study entry. Data from previous randomized controlled trials on breast cancer screening were combined, and cumulative and yearly breast cancer mortality rates and relative risks (RRs) were calculated for women offered screening compared to those not offered screening. At 7 years of follow-up, no reduction in breast cancer mortality from screening starting at ages 40-49 was found. At 10 years of follow-up, a nonsignificant reduction in breast cancer mortality was seen for women aged 40-49 at entry (RR = 0.93; 95% CI: 0.77-1.11). A nonsignificant excess of breast cancer mortality in those offered screening aged 40-49 was observed during the early years of follow-up in several trials. While the favorable effect of screening was observed within the first 5 years of study entry for women aged 50 or more, no similar effect was seen for women aged 40-49. The delayed effect for the 40-49 cohort may be attributable to 1) a biological difference in the effects of screening, which may be related to the onset of menopause, and 2) screening that occurred when women were aged 50 or more rather than before that age. [Monogr Natl Cancer Inst 1997;22:69-72]

International Journal of Cancer, 1997

... Occurrence of melanoma was denser for chronically than intermittently exposed sites in both N... more ... Occurrence of melanoma was denser for chronically than intermittently exposed sites in both New Zealand and Canada. The highest incidence rate per unit area was for the ears in men which was more than 5 times the rate for the entire body in each country. ...

Cancer, 1996

... Hendrick E, Rutledge JH, Smith RA. Benefit of mammography screening in women ages 40 to 49 ye... more ... Hendrick E, Rutledge JH, Smith RA. Benefit of mammography screening in women ages 40 to 49 years: current evidence from randomized controlled trials. ... Elwood JM, Cox B, Richardson AK. The effectiveness of breast cancer screening by mammography in younger women. ...

Journal of Global Oncology, 2016

Purpose Cervical cancer is a common cancer among women worldwide. An estimated 528,000 new cases ... more Purpose Cervical cancer is a common cancer among women worldwide. An estimated 528,000 new cases and 266,000 deaths occurred in 2012. More than 85% of invasive cervical cancer cases occur in low- and middle-income countries. Cervical cancer ranks as the most common cancer among women in Ghana. We conducted a retrospective study to assess the descriptive epidemiology of cervical cancer in Ghana. We describe cervical cancer incidence and mortality rates for the regions served by two large hospitals in Ghana. Patients and Methods Information for women diagnosed with invasive cervical cancer between 2010 and 2013 was collected from the Komfo Anokye and Korle Bu Teaching Hospitals through review of medical, computer, and pathology records at the oncology units and the obstetrics and gynecology departments. Telephone interviews were also conducted with patients and relatives. Data were analyzed using summary statistics. Results A total of 1,725 women with cervical cancer were included in ...

Current Oncology Reports, 2011

There has been a great deal of controversy regarding the change in breast cancer screening recomm... more There has been a great deal of controversy regarding the change in breast cancer screening recommendations released by the US Preventive Services Task Force in November 2009. Despite limited new data, the Task Force changed their previous recommendations delaying initial screening of asymptomatic women from age 40 to age 50 and recommending biennial rather than annual breast cancer screening. It

JNCI Monographs, 1997

This meta-analysis assesses the effectiveness of breast screening by year from the start of scree... more This meta-analysis assesses the effectiveness of breast screening by year from the start of screening for women aged 40-49 at study entry. Data from previous randomized controlled trials on breast cancer screening were combined, and cumulative and yearly breast cancer mortality rates and relative risks (RRs) were calculated for women offered screening compared to those not offered screening. At 7 years of follow-up, no reduction in breast cancer mortality from screening starting at ages 40-49 was found. At 10 years of follow-up, a nonsignificant reduction in breast cancer mortality was seen for women aged 40-49 at entry (RR = 0.93; 95% CI: 0.77-1.11). A nonsignificant excess of breast cancer mortality in those offered screening aged 40-49 was observed during the early years of follow-up in several trials. While the favorable effect of screening was observed within the first 5 years of study entry for women aged 50 or more, no similar effect was seen for women aged 40-49. The delayed effect for the 40-49 cohort may be attributable to 1) a biological difference in the effects of screening, which may be related to the onset of menopause, and 2) screening that occurred when women were aged 50 or more rather than before that age. [Monogr Natl Cancer Inst 1997;22:69-72]

International Journal of Cancer, 1997

... Occurrence of melanoma was denser for chronically than intermittently exposed sites in both N... more ... Occurrence of melanoma was denser for chronically than intermittently exposed sites in both New Zealand and Canada. The highest incidence rate per unit area was for the ears in men which was more than 5 times the rate for the entire body in each country. ...

Cancer, 1996

... Hendrick E, Rutledge JH, Smith RA. Benefit of mammography screening in women ages 40 to 49 ye... more ... Hendrick E, Rutledge JH, Smith RA. Benefit of mammography screening in women ages 40 to 49 years: current evidence from randomized controlled trials. ... Elwood JM, Cox B, Richardson AK. The effectiveness of breast cancer screening by mammography in younger women. ...

Journal of Global Oncology, 2016

Purpose Cervical cancer is a common cancer among women worldwide. An estimated 528,000 new cases ... more Purpose Cervical cancer is a common cancer among women worldwide. An estimated 528,000 new cases and 266,000 deaths occurred in 2012. More than 85% of invasive cervical cancer cases occur in low- and middle-income countries. Cervical cancer ranks as the most common cancer among women in Ghana. We conducted a retrospective study to assess the descriptive epidemiology of cervical cancer in Ghana. We describe cervical cancer incidence and mortality rates for the regions served by two large hospitals in Ghana. Patients and Methods Information for women diagnosed with invasive cervical cancer between 2010 and 2013 was collected from the Komfo Anokye and Korle Bu Teaching Hospitals through review of medical, computer, and pathology records at the oncology units and the obstetrics and gynecology departments. Telephone interviews were also conducted with patients and relatives. Data were analyzed using summary statistics. Results A total of 1,725 women with cervical cancer were included in ...

Current Oncology Reports, 2011

There has been a great deal of controversy regarding the change in breast cancer screening recomm... more There has been a great deal of controversy regarding the change in breast cancer screening recommendations released by the US Preventive Services Task Force in November 2009. Despite limited new data, the Task Force changed their previous recommendations delaying initial screening of asymptomatic women from age 40 to age 50 and recommending biennial rather than annual breast cancer screening. It