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Bruno Hubesch

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Research paper thumbnail of Phosphorus 31 magnetic resonance spectroscopy of perifused human placental villi under varying oxygen concentrations

American Journal of Obstetrics and Gynecology, 1993

ABSTRACT Initial phosphorus magnetic resonance spectroscopy observations on the oxygen metabolism... more ABSTRACT Initial phosphorus magnetic resonance spectroscopy observations on the oxygen metabolism of placental villi from normal term pregnancies are described. Villi were suspended in medium and perifused within a custom-designed 30 mm nuclear magnetic resonance probe in a superconducting vertical nuclear magnetic resonance magnet where pH, temperature, and oxygenation were monitored. Phosphorus resonances were observed from adenosine triphosphate, phosphomonoesters. inorganic phosphate, and phosphodiesters. No phosphocreatine signal was observed. The placental villus tissue responded to an increase in oxygen concentration of the perifusate with a rise in the adenosine triphosphate level and a concomitant decline in the inorganic phosphate and the phosphomonoester signals. The changes observed reflect continuing dynamic glycolysis and oxidative phosphorylation. The absence of a phosphocreatine peak suggests that aerobic pathways not driven by creatine kinase are important for placental metabolism. Our system demonstrates dynamic oxygen metabolism in perifused viable placental villus tissue by means of magnetic resonance spectroscopy.

Research paper thumbnail of LRI AMBIT chemoinformatic system with IUCLID6 substance database to support read-across of substance endpoint data and category formation

Research paper thumbnail of Reach: Analoge Strukturen suchen

Nachrichten aus der Chemie, 2016

Research paper thumbnail of Easy Chemical Safety Prediction

Research paper thumbnail of Cellulase fabric-conditioning compositions

Research paper thumbnail of Fabric softener compositions

A method for imparting improved properties to the tissue folds reduction and / or ease of ironing... more A method for imparting improved properties to the tissue folds reduction and / or ease of ironing, wherein the method comprises applying the fabric a fabric softening composition comprising: (c) a softening agent cationic fabric; and (d) an emulsified silicone; in which the average droplet size of silicone in the emulsion is at least 0.39 mum and not more than 25 mum, and the silicone is emulsified with an emulsifier comprising one or more cationic surfactants and wherein the viscosity silicone before emulsification of 0.045 m 2 / s (45,000 cSt) 0.75 m2 / s (750,000 cSt).

Research paper thumbnail of Fabric softener compositions

Research paper thumbnail of Stabilised fabric softening compositions

Research paper thumbnail of Concentrated Liquid Fabric Softener Compositions Containing Biodegradable Fabric Softeners

Research paper thumbnail of Laundry composition containing dye fixatives and cellulase

Research paper thumbnail of Laundry Additive Compositions Including Dispersible Polyolefin and Method for Using Same

Research paper thumbnail of Cellulase fabric-conditioning compositions

Research paper thumbnail of Fabric conditioning compositions

Research paper thumbnail of Laundry additive compositions including dispersible polyolefin

Research paper thumbnail of Wrinkle reducing composition

Research paper thumbnail of Wrinkle reducing composition

Research paper thumbnail of Cellulase Fabric-Conditioning Compositions

Research paper thumbnail of Fabric softening compositions

Research paper thumbnail of Wrinkle resistant composition

Research paper thumbnail of Domestic treatment of fabrics with film-forming materials and blowing agents

Research paper thumbnail of Phosphorus 31 magnetic resonance spectroscopy of perifused human placental villi under varying oxygen concentrations

American Journal of Obstetrics and Gynecology, 1993

ABSTRACT Initial phosphorus magnetic resonance spectroscopy observations on the oxygen metabolism... more ABSTRACT Initial phosphorus magnetic resonance spectroscopy observations on the oxygen metabolism of placental villi from normal term pregnancies are described. Villi were suspended in medium and perifused within a custom-designed 30 mm nuclear magnetic resonance probe in a superconducting vertical nuclear magnetic resonance magnet where pH, temperature, and oxygenation were monitored. Phosphorus resonances were observed from adenosine triphosphate, phosphomonoesters. inorganic phosphate, and phosphodiesters. No phosphocreatine signal was observed. The placental villus tissue responded to an increase in oxygen concentration of the perifusate with a rise in the adenosine triphosphate level and a concomitant decline in the inorganic phosphate and the phosphomonoester signals. The changes observed reflect continuing dynamic glycolysis and oxidative phosphorylation. The absence of a phosphocreatine peak suggests that aerobic pathways not driven by creatine kinase are important for placental metabolism. Our system demonstrates dynamic oxygen metabolism in perifused viable placental villus tissue by means of magnetic resonance spectroscopy.

Research paper thumbnail of LRI AMBIT chemoinformatic system with IUCLID6 substance database to support read-across of substance endpoint data and category formation

Research paper thumbnail of Reach: Analoge Strukturen suchen

Nachrichten aus der Chemie, 2016

Research paper thumbnail of Easy Chemical Safety Prediction

Research paper thumbnail of Cellulase fabric-conditioning compositions

Research paper thumbnail of Fabric softener compositions

A method for imparting improved properties to the tissue folds reduction and / or ease of ironing... more A method for imparting improved properties to the tissue folds reduction and / or ease of ironing, wherein the method comprises applying the fabric a fabric softening composition comprising: (c) a softening agent cationic fabric; and (d) an emulsified silicone; in which the average droplet size of silicone in the emulsion is at least 0.39 mum and not more than 25 mum, and the silicone is emulsified with an emulsifier comprising one or more cationic surfactants and wherein the viscosity silicone before emulsification of 0.045 m 2 / s (45,000 cSt) 0.75 m2 / s (750,000 cSt).

Research paper thumbnail of Fabric softener compositions

Research paper thumbnail of Stabilised fabric softening compositions

Research paper thumbnail of Concentrated Liquid Fabric Softener Compositions Containing Biodegradable Fabric Softeners

Research paper thumbnail of Laundry composition containing dye fixatives and cellulase

Research paper thumbnail of Laundry Additive Compositions Including Dispersible Polyolefin and Method for Using Same

Research paper thumbnail of Cellulase fabric-conditioning compositions

Research paper thumbnail of Fabric conditioning compositions

Research paper thumbnail of Laundry additive compositions including dispersible polyolefin

Research paper thumbnail of Wrinkle reducing composition

Research paper thumbnail of Wrinkle reducing composition

Research paper thumbnail of Cellulase Fabric-Conditioning Compositions

Research paper thumbnail of Fabric softening compositions

Research paper thumbnail of Wrinkle resistant composition

Research paper thumbnail of Domestic treatment of fabrics with film-forming materials and blowing agents

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